Research output per year
Research output per year
- 1 - 50 out of 266 results
Search results
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2020
Androgen-Influenced Polarization of Activin A-Producing Macrophages Accompanies Post-pyelonephritic Renal Scarring
Hreha, T. N., Collins, C. A., Daugherty, A. L., Griffith, J. M., Hruska, K. A. & Hunstad, D. A., Jul 28 2020, In: Frontiers in immunology. 11, 1641.Research output: Contribution to journal › Article › peer-review
Open Access8 Scopus citations -
2019
Signal regulatory protein alpha initiates cachexia through muscle to adipose tissue crosstalk
Wu, J., Dong, J., Verzola, D., Hruska, K., Garibotto, G., Hu, Z., Mitch, W. E. & Thomas, S. S., Dec 1 2019, In: Journal of Cachexia, Sarcopenia and Muscle. 10, 6, p. 1210-1227 18 p.Research output: Contribution to journal › Article › peer-review
Open Access17 Scopus citations -
Sotatercept Safety and Effects on Hemoglobin, Bone, and Vascular Calcification
Coyne, D. W., Singh, H. N., Smith, W. T., Giuseppi, A. C., Connarn, J. N., Sherman, M. L., Dellanna, F., Malluche, H. H. & Hruska, K. A., Nov 2019, In: Kidney International Reports. 4, 11, p. 1585-1597 13 p.Research output: Contribution to journal › Article › peer-review
Open Access17 Scopus citations -
2018
Androgen exposure potentiates formation of intratubular communities and renal abscesses by Escherichia coli
Olson, P. D., McLellan, L. K., Hreha, T. N., Liu, A., Briden, K. E., Hruska, K. A. & Hunstad, D. A., Sep 2018, In: Kidney International. 94, 3, p. 502-513 12 p.Research output: Contribution to journal › Article › peer-review
Open Access17 Scopus citations -
Exogenous BMP7 in aortae of rats with chronic uremia ameliorates expression of profibrotic genes, but does not reverse established vascular calcification
Gravesen, E., Mace, M. L., Nordholm, A., Hofman-Bang, J., Hruska, K., Nielsen, C. H., Kjær, A., Olgaard, K. & Lewin, E., Jan 2018, In: PloS one. 13, 1, e0190820.Research output: Contribution to journal › Article › peer-review
Open Access16 Scopus citations -
The activin receptor is stimulated in the skeleton, vasculature, heart, and kidney during chronic kidney disease
Williams, M. J., Sugatani, T., Agapova, O. A., Fang, Y., Gaut, J. P., Faugere, M. C., Malluche, H. H. & Hruska, K. A., Jan 2018, In: Kidney International. 93, 1, p. 147-158 12 p.Research output: Contribution to journal › Article › peer-review
Open Access44 Scopus citations -
2017
Ligand trap of the activin receptor type IIA inhibits osteoclast stimulation of bone remodeling in diabetic mice with chronic kidney disease
Sugatani, T., Agapova, O. A., Fang, Y., Berman, A. G., Wallace, J. M., Malluche, H. H., Faugere, M. C., Smith, W., Sung, V. & Hruska, K. A., Jan 1 2017, In: Kidney International. 91, 1, p. 86-95 10 p.Research output: Contribution to journal › Article › peer-review
Open Access43 Scopus citations -
Renal scar formation and kidney function following antibiotic-treated murine pyelonephritis
Olson, P. D., McLellan, L. K., Liu, A., Briden, K. E., Tiemann, K. M., Daugherty, A. L., Hruska, K. A. & Hunstad, D. A., Nov 1 2017, In: DMM Disease Models and Mechanisms. 10, 11, p. 1371-1379 9 p.Research output: Contribution to journal › Article › peer-review
Open Access17 Scopus citations -
2016
Androgens enhance male urinary tract infection severity in a new model
Olson, P. D., Hruska, K. A. & Hunstad, D. A., Jun 2016, In: Journal of the American Society of Nephrology. 27, 6, p. 1625-1634 10 p.Research output: Contribution to journal › Article › peer-review
47 Scopus citations -
Bone mineral density and progression of subclinical atherosclerosis in African-Americans with type 2 diabetes
Wagenknecht, L. E., Divers, J., Register, T. C., Russell, G. B., Bowden, D. W., Xu, J., Langefeld, C. D., Lenchik, L., Hruska, K. A., Carr, J. J. & Freedman, B. I., Nov 2016, In: Journal of Clinical Endocrinology and Metabolism. 101, 11, p. 4135-4141 7 p.Research output: Contribution to journal › Article › peer-review
Open Access13 Scopus citations -
Fibroblast growth factor-23 and chronic allograft injury in pediatric renal transplant recipients: A Midwest Pediatric Nephrology Consortium study
Seifert, M. E., Ashoor, I. F., Chiang, M. L., Chishti, A. S., Dietzen, D. J., Gipson, D. S., Janjua, H. S., Selewski, D. T. & Hruska, K. A., May 1 2016, In: Pediatric transplantation. 20, 3, p. 378-387 10 p.Research output: Contribution to journal › Article › peer-review
3 Scopus citations -
Ligand trap for the activin type IIA receptor protects against vascular disease and renal fibrosis in mice with chronic kidney disease
Agapova, O. A., Fang, Y., Sugatani, T., Seifert, M. E. & Hruska, K. A., 2016, In: Kidney International. 89, 6, p. 1231-1243 13 p.Research output: Contribution to journal › Article › peer-review
Open Access54 Scopus citations -
2015
Clinical phenotype of APOL1 nephropathy in young relatives of patients with end-stage renal disease
Anyaegbu, E. I., Shaw, A. S., Hruska, K. A. & Jain, S., Jun 1 2015, In: Pediatric Nephrology. 30, 6, p. 983-989 7 p.Research output: Contribution to journal › Article › peer-review
15 Scopus citations -
Plasma FGF23 and Calcified Atherosclerotic Plaque in African Americans with Type 2 Diabetes Mellitus
Freedman, B. I., Divers, J., Russell, G. B., Palmer, N. D., Bowden, D. W., Carr, J. J., Wagenknecht, L. E., Hightower, R. C., Xu, J., Smith, S. C., Langefeld, C. D., Hruska, K. A. & Register, T. C., Dec 1 2015, In: American Journal of Nephrology. 42, 6, p. 391-401 11 p.Research output: Contribution to journal › Article › peer-review
Open Access27 Scopus citations -
SIRT6 deficiency culminates in low-turnover osteopenia
Sugatani, T., Agapova, O., Malluche, H. H. & Hruska, K. A., Dec 1 2015, In: Bone. 81, p. 168-177 10 p.Research output: Contribution to journal › Article › peer-review
26 Scopus citations -
2014
CKD-induced wingless/integration1 inhibitors and phosphorus cause the CKD-mineral and bone disorder
Fang, Y., Ginsberg, C., Seifert, M., Agapova, O., Sugatani, T., Register, T. C., Freedman, B. I., Monier-Faugere, M. C., Malluche, H. & Hruska, K. A., Aug 1 2014, In: Journal of the American Society of Nephrology. 25, 8, p. 1760-1773 14 p.Research output: Contribution to journal › Article › peer-review
Open Access132 Scopus citations -
Early chronic kidney disease-mineral bone disorder stimulates vascular calcification
Fang, Y., Ginsberg, C., Sugatani, T., Monier-Faugere, M. C., Malluche, H. & Hruska, K. A., Jan 2014, In: Kidney International. 85, 1, p. 142-150 9 p.Research output: Contribution to journal › Article › peer-review
Open Access156 Scopus citations -
Expression of DGCR8-dependent microRNAs is indispensable for osteoclastic development and bone-resorbing activity
Sugatani, T., Hildreth, B. E., Toribio, R. E., Malluche, H. H. & Hruska, K. A., Jun 2014, In: Journal of cellular biochemistry. 115, 6, p. 1043-1047 5 p.Research output: Contribution to journal › Article › peer-review
24 Scopus citations -
HDAC dependent transcriptional repression of Bmp-7 potentiates TGF-β mediated renal fibrosis in obstructive uropathy
Manson, S. R., Song, J. B., Hruska, K. A. & Austin, P. F., Jan 2014, In: Journal of Urology. 191, 1, p. 242-252 11 p.Research output: Contribution to journal › Article › peer-review
32 Scopus citations -
Left ventricular mass progression despite stable blood pressure and kidney function in stage 3 chronic kidney disease
Seifert, M. E., De Las Fuentes, L., Ginsberg, C., Rothstein, M., Dietzen, D. J., Cheng, S. C., Ross, W., Windus, D., Dávila-Román, V. G. & Hruska, K. A., Jun 2014, In: American Journal of Nephrology. 39, 5, p. 392-399 8 p.Research output: Contribution to journal › Article › peer-review
Open Access27 Scopus citations -
Sclerostin is positively associated with bone mineral density in men and women and negatively associated with carotid calcified atherosclerotic plaque in men from the African American-diabetes heart study
Register, T. C., Hruska, K. A., Divers, J., Bowden, D. W., Palmer, N. D., Carr, J. J., Wagenknecht, L. E., Hightower, R. C., Xu, J., Smith, S. C., Dietzen, D. J., Langefeld, C. D. & Freedman, B. I., Jan 2014, In: Journal of Clinical Endocrinology and Metabolism. 99, 1, p. 315-321 7 p.Research output: Contribution to journal › Article › peer-review
Open Access45 Scopus citations -
2013
Buyer beware! Doctor be aware! - Answers
Anyaegbu, E., Keefe Davis, T., Kniska, K., Hruska, K. & Beck, A., Sep 2013, In: Pediatric Nephrology. 28, 9, p. 1787-1790 4 p.Research output: Contribution to journal › Article › peer-review
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Down-regulation of miR-21 biogenesis by estrogen action contributes to osteoclastic apoptosis
Sugatani, T. & Hruska, K. A., Jun 2013, In: Journal of cellular biochemistry. 114, 6, p. 1217-1222 6 p.Research output: Contribution to journal › Article › peer-review
82 Scopus citations -
Effects of phosphate binder therapy on vascular stiffness in early-stage chronic kidney disease
Seifert, M. E., De Las Fuentes, L., Rothstein, M., Dietzen, D. J., Bierhals, A. J., Cheng, S. C., Ross, W., Windus, D., Dávila-Román, V. G. & Hruska, K. A., Aug 2013, In: American Journal of Nephrology. 38, 2, p. 158-167 10 p.Research output: Contribution to journal › Article › peer-review
Open Access62 Scopus citations -
Phosphate homeostasis in CKD: Report of a scientific symposium sponsored by the national kidney foundation
Block, G. A., Ix, J. H., Ketteler, M., Martin, K. J., Thadhani, R. I., Tonelli, M., Wolf, M., Jüppner, H., Hruska, K. & Wheeler, D. C., Sep 2013, In: American Journal of Kidney Diseases. 62, 3, p. 457-473 17 p.Research output: Contribution to journal › Article › peer-review
67 Scopus citations -
Plasma Dickkopf1 (DKK1) concentrations negatively associate with atherosclerotic calcified plaque in African-Americans with type 2 diabetes
Register, T. C., Hruska, K. A., Divers, J., Bowden, D. W., Palmer, N. D., Carr, J. J., Wagenknecht, L. E., Hightower, R. C., Xu, J., Smith, S. C., Dietzen, D. J., Langefeld, C. D. & Freedman, B. I., Jan 2013, In: Journal of Clinical Endocrinology and Metabolism. 98, 1, p. E60-E65Research output: Contribution to journal › Article › peer-review
Open Access46 Scopus citations -
Relationships between serum adiponectin and bone density, adiposity and calcified atherosclerotic plaque in the african american-diabetes heart study
Register, T. C., Divers, J., Bowden, D. W., Carr, J. J., Lenchik, L., Wagenknecht, L. E., Hightower, R. C., Xu, J., Smith, S. C., Hruska, K. A., Langefeld, C. D. & Freedman, B. I., May 2013, In: Journal of Clinical Endocrinology and Metabolism. 98, 5, p. 1916-1922 7 p.Research output: Contribution to journal › Article › peer-review
Open Access19 Scopus citations -
2012
Relationships between serum MCP-1 and subclinical kidney disease: African American-Diabetes Heart Study
Murea, M., Register, T. C., Divers, J., Bowden, D. W., Carr, J. J., Hightower, C. R., Xu, J., Smith, S. C., Hruska, K. A., Langefeld, C. D. & Freedman, B. I., 2012, In: BMC Nephrology. 13, 1, 148.Research output: Contribution to journal › Article › peer-review
Open Access19 Scopus citations -
Traditional and targeted exome sequencing reveals common, rare and novel functional deleterious variants in RET-signaling complex in a cohort of living US patients with urinary tract malformations
Chatterjee, R., Ramos, E., Hoffman, M., Vanwinkle, J., Martin, D. R., Davis, T. K., Hoshi, M., Hmiel, S. P., Beck, A., Hruska, K., Coplen, D., Liapis, H., Mitra, R., Druley, T., Austin, P. & Jain, S., Nov 2012, In: Human genetics. 131, 11, p. 1725-1738 14 p.Research output: Contribution to journal › Article › peer-review
76 Scopus citations -
2011
A microRNA expression signature of osteoclastogenesis
Sugatani, T., Vacher, J. & Hruska, K. A., Mar 31 2011, In: Blood. 117, 13, p. 3648-3657 10 p.Research output: Contribution to journal › Article › peer-review
233 Scopus citations -
Endogenous BMP-7 is a critical molecular determinant of the reversibility of obstruction-induced renal injuries
Manson, S. R., Niederhoff, R. A., Hruska, K. A. & Austin, P. F., Dec 2011, In: American Journal of Physiology - Renal Physiology. 301, 6, p. F1293-F1302Research output: Contribution to journal › Article › peer-review
22 Scopus citations -
Relationships between calcified atherosclerotic plaque and bone mineral density in African Americans with type 2 diabetes
Divers, J., Register, T. C., Langefeld, C. D., Wagenknecht, L. E., Bowden, D. W., Carr, J. J., Hightower, R. C., Xu, J., Hruska, K. A. & Freedman, B. I., Jul 2011, In: Journal of Bone and Mineral Research. 26, 7, p. 1554-1560 7 p.Research output: Contribution to journal › Article › peer-review
35 Scopus citations -
RGS4, a GTPase activator, improves renal function in ischemia-reperfusion injury
Siedlecki, A. M., Jin, X., Thomas, W., Hruska, K. A. & Muslin, A. J., Aug 1 2011, In: Kidney International. 80, 3, p. 263-271 9 p.Research output: Contribution to journal › Article › peer-review
Open Access22 Scopus citations -
The BMP-7Smad1/5/8 pathway promotes kidney repair after obstruction induced renal injury
Manson, S. R., Niederhoff, R. A., Hruska, K. A. & Austin, P. F., Jun 2011, In: Journal of Urology. 185, 6 SUPPL., p. 2523-2530 8 p.Research output: Contribution to journal › Article › peer-review
51 Scopus citations -
2010
Cardiovascular risk in chronic kidney disease (CKD): The CKD-mineral bone disorder (CKD-MBD)
Hruska, K. A., Choi, E. T., Memon, I., Davis, T. K. & Mathew, S., Apr 2010, In: Pediatric Nephrology. 25, 4, p. 769-778 10 p.Research output: Contribution to journal › Article › peer-review
60 Scopus citations -
The new kidney disease: Improving global outcomes (KDIGO) guidelines - Expert clinical focus on bone and vascular calcification
London, G., Coyne, D., Hruska, K., Malluche, H. H. & Martin, K. J., Dec 2010, In: Clinical Nephrology. 74, 6, p. 423-432 10 p.Research output: Contribution to journal › Article › peer-review
42 Scopus citations -
2009
Bone morphogenetic protein 7 (BMP7) gene polymorphisms are associated with inverse relationships between vascular calcification and BMD: The diabetes heart study
Freedman, B. I., Bowden, D. W., Ziegler, J. T., Langefeld, C. D., Lehtinen, A. B., Rudock, M. E., Lenchik, L., Hruska, K. A., Register, T. C. & Carr, J. J., Oct 2009, In: Journal of Bone and Mineral Research. 24, 10, p. 1719-1727 9 p.Research output: Contribution to journal › Article › peer-review
Open Access40 Scopus citations -
CKD accelerates development of neointimal hyperplasia in arteriovenous fistulas
Kokubo, T., Ishikawa, N., Uchida, H., Chasnoff, S. E., Xie, X., Mathew, S., Hruska, K. A. & Choi, E. T., Jun 2009, In: Journal of the American Society of Nephrology. 20, 6, p. 1236-1245 10 p.Research output: Contribution to journal › Article › peer-review
Open Access94 Scopus citations -
Impaired micro-RNA pathways diminish osteoclast differentiation and function
Sugatani, T. & Hruska, K. A., Feb 13 2009, In: Journal of Biological Chemistry. 284, 7, p. 4667-4678 12 p.Research output: Contribution to journal › Article › peer-review
Open Access192 Scopus citations -
The Pathogenesis of Vascular Calcification in the Chronic Kidney Disease Mineral Bone Disorder: The Links Between Bone and the Vasculature
Hruska, K. A., Mathew, S., Lund, R. J., Memon, I. & Saab, G., Mar 2009, In: Seminars in Nephrology. 29, 2, p. 156-165 10 p.Research output: Contribution to journal › Article › peer-review
49 Scopus citations -
2008
The mechanism of phosphorus as a cardiovascular risk factor in CKD
Mathew, S., Tustison, K. S., Sugatani, T., Chaudhary, L. R., Rifas, L. & Hruska, K. A., Jun 2008, In: Journal of the American Society of Nephrology. 19, 6, p. 1092-1105 14 p.Research output: Contribution to journal › Article › peer-review
Open Access211 Scopus citations -
Vitamin D receptor activators can protect against vascular calcification
Mathew, S., Lund, R. J., Chaudhary, L. R., Geurs, T. & Hruska, K. A., Aug 2008, In: Journal of the American Society of Nephrology. 19, 8, p. 1509-1519 11 p.Research output: Contribution to journal › Article › peer-review
Open Access206 Scopus citations -
2007
Bone morphogenetic protein-7 delays podocyte injury due to high glucose
De Petris, L., Hruska, K. A., Chiechio, S. & Liapis, H., Dec 2007, In: Nephrology Dialysis Transplantation. 22, 12, p. 3442-3450 9 p.Research output: Contribution to journal › Article › peer-review
Open Access58 Scopus citations -
MicroRNA-223 is a key factor in osteoclast differentiation
Sugatani, T. & Hruska, K. A., Jul 1 2007, In: Journal of cellular biochemistry. 101, 4, p. 996-999 4 p.Research output: Contribution to journal › Article › peer-review
163 Scopus citations -
Renal osteodystrophy, phosphate homeostasis, and vascular calcification
Hruska, K. A., Saab, G., Mathew, S. & Lund, R., Jul 2007, In: Seminars in Dialysis. 20, 4, p. 309-315 7 p.Research output: Contribution to journal › Article › peer-review
86 Scopus citations -
Reversal of the adynamic bone disorder and decreased vascular calcification in chronic kidney disease by sevelamer carbonate therapy
Mathew, S., Lund, R. J., Strebeck, F., Tustison, K. S., Geurs, T. & Hruska, K. A., Jan 2007, In: Journal of the American Society of Nephrology. 18, 1, p. 122-130 9 p.Research output: Contribution to journal › Article › peer-review
Open Access99 Scopus citations -
2005
Akt1/Akt2 and mammalian target of rapamycin/Bim play critical roles in osteoclast differentiation and survival, respectively, whereas Akt is dispensable for cell survival in isolated osteoclast precursors
Sugatani, T. & Hruska, K. A., Feb 4 2005, In: Journal of Biological Chemistry. 280, 5, p. 3583-3589 7 p.Research output: Contribution to journal › Article › peer-review
Open Access177 Scopus citations -
Connections between vascular calcification and progression of chronic kidney disease: Therapeutic alternatives
Hruska, K. A., Mathew, S., Davies, M. R. & Lund, R. J., Dec 2005, In: Kidney International. 68, SUPPL. 99, p. S-142-S-151Research output: Contribution to journal › Article › peer-review
Open Access18 Scopus citations -
In Vivo Transplantation of Neonatal Ovine Neocartilage Allografts
Lu, Y., Bogdanske, J., Kalscheur, V., Davis Adkisson, H., Hruska, K. A., Maloney, W., Grodzinsky Cefalu, A. J., Cheung, R. & Markel, M. D., Jun 1 2005, In: Journal of Knee Surgery. 18, 1, p. 31-42 12 p.Research output: Contribution to journal › Article › peer-review
18 Scopus citations -
Low turnover osteodystrophy and vascular calcification are amenable to skeletal anabolism in an animal model of chronic kidney disease and the metabolic syndrome
Davies, M. R., Lund, R. J., Mathew, S. & Hruska, K. A., 2005, In: Journal of the American Society of Nephrology. 16, 4, p. 917-928 12 p.Research output: Contribution to journal › Article › peer-review
Open Access138 Scopus citations