Research output per year
Research output per year
- 1 - 50 out of 327 results
Search results
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2024
In chronic kidney disease altered cardiac metabolism precedes cardiac hypertrophy
Williams, M. J., Halabi, C. M., Patel, H. M., Joseph, Z., McCommis, K., Weinheimer, C., Kovacs, A., Lima, F., Finck, B., Malluche, H. & Hruska, K. A., May 2024, In: American Journal of Physiology - Renal Fluid and Electrolyte Physiology. 326, 5, p. F751-F767Research output: Contribution to journal › Article › peer-review
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2023
Acidosis in CKD May Affect Mineralization of Newly Formed Bone According to HR-pQCT and Quantitative Back Scatter Electron Imaging
Williams, M. J. & Hruska, K. A., Apr 1 2023, In: Journal of the American Society of Nephrology. 34, 4, p. 520-523 4 p.Research output: Contribution to journal › Editorial
Open Access -
Updates in the chronic kidney disease-mineral bone disorder show the role of osteocytic proteins, a potential mechanism of the bone—Vascular paradox, a therapeutic target, and a biomarker
Williams, M. J., White, S. C., Joseph, Z. & Hruska, K. A., Jan 26 2023, In: Frontiers in Physiology. 14, 1120308.Research output: Contribution to journal › Review article › peer-review
Open Access6 Scopus citations -
2021
FGF23-an established master regulator of phosphate metabolism
Hruska, K. A. & Williams, M. J., Jan 1 2021, Fibroblast Growth Factor 23. Elsevier, p. 7-21 15 p.Research output: Chapter in Book/Report/Conference proceeding › Chapter › peer-review
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2020
Androgen-Influenced Polarization of Activin A-Producing Macrophages Accompanies Post-pyelonephritic Renal Scarring
Hreha, T. N., Collins, C. A., Daugherty, A. L., Griffith, J. M., Hruska, K. A. & Hunstad, D. A., Jul 28 2020, In: Frontiers in immunology. 11, 1641.Research output: Contribution to journal › Article › peer-review
Open Access16 Scopus citations -
2019
Chronic Kidney Disease-Mineral and Bone Disorders
Hruska, K. A., Williams, M. J. & Sugatani, T., Jan 1 2019, Chronic Renal Disease. Elsevier, p. 551-569 19 p.Research output: Chapter in Book/Report/Conference proceeding › Chapter › peer-review
3 Scopus citations -
New pathogenic insights inform therapeutic target development for renal osteodystrophy
Hruska, K. A. & Mahjoub, M. R., Feb 2019, In: Kidney International. 95, 2, p. 261-263 3 p.Research output: Contribution to journal › Comment/debate
Open Access2 Scopus citations -
Signal regulatory protein alpha initiates cachexia through muscle to adipose tissue crosstalk
Wu, J., Dong, J., Verzola, D., Hruska, K., Garibotto, G., Hu, Z., Mitch, W. E. & Thomas, S. S., Dec 1 2019, In: Journal of Cachexia, Sarcopenia and Muscle. 10, 6, p. 1210-1227 18 p.Research output: Contribution to journal › Article › peer-review
Open Access19 Scopus citations -
Sotatercept Safety and Effects on Hemoglobin, Bone, and Vascular Calcification
Coyne, D. W., Singh, H. N., Smith, W. T., Giuseppi, A. C., Connarn, J. N., Sherman, M. L., Dellanna, F., Malluche, H. H. & Hruska, K. A., Nov 2019, In: Kidney International Reports. 4, 11, p. 1585-1597 13 p.Research output: Contribution to journal › Article › peer-review
Open Access25 Scopus citations -
2018
Androgen exposure potentiates formation of intratubular communities and renal abscesses by Escherichia coli
Olson, P. D., McLellan, L. K., Hreha, T. N., Liu, A., Briden, K. E., Hruska, K. A. & Hunstad, D. A., Sep 2018, In: Kidney International. 94, 3, p. 502-513 12 p.Research output: Contribution to journal › Article › peer-review
Open Access25 Scopus citations -
Correction: Renal scar formation and kidney function following antibiotic-treated murine pyelonephritis (DMM Disease Models and Mechanisms (2018) 10 1371-1379) DOI: 10.1242/dmm.030130)
Olson, P. D., McLellan, L. K., Liu, A., Briden, K. E., Tiemann, K. M., Daugherty, A. L., Hruska, K. A. & Hunstad, D. A., Sep 2018, In: DMM Disease Models and Mechanisms. 11, 9, dmm036798.Research output: Contribution to journal › Comment/debate
Open Access2 Scopus citations -
Exogenous BMP7 in aortae of rats with chronic uremia ameliorates expression of profibrotic genes, but does not reverse established vascular calcification
Gravesen, E., Mace, M. L., Nordholm, A., Hofman-Bang, J., Hruska, K., Nielsen, C. H., Kjær, A., Olgaard, K. & Lewin, E., Jan 2018, In: PloS one. 13, 1, e0190820.Research output: Contribution to journal › Article › peer-review
Open Access17 Scopus citations -
The activin receptor is stimulated in the skeleton, vasculature, heart, and kidney during chronic kidney disease
Williams, M. J., Sugatani, T., Agapova, O. A., Fang, Y., Gaut, J. P., Faugere, M. C., Malluche, H. H. & Hruska, K. A., Jan 2018, In: Kidney International. 93, 1, p. 147-158 12 p.Research output: Contribution to journal › Article › peer-review
Open Access51 Scopus citations -
2017
Crosstalk between kidney and bone – Bench to bedside
Hruska, K. A., Lanske, B. & Moe, O. W., Jul 2017, In: Bone. 100, p. 1-3 3 p.Research output: Contribution to journal › Editorial
3 Scopus citations -
Ligand trap of the activin receptor type IIA inhibits osteoclast stimulation of bone remodeling in diabetic mice with chronic kidney disease
Sugatani, T., Agapova, O. A., Fang, Y., Berman, A. G., Wallace, J. M., Malluche, H. H., Faugere, M. C., Smith, W., Sung, V. & Hruska, K. A., Jan 1 2017, In: Kidney International. 91, 1, p. 86-95 10 p.Research output: Contribution to journal › Article › peer-review
Open Access45 Scopus citations -
Renal scar formation and kidney function following antibiotic-treated murine pyelonephritis
Olson, P. D., McLellan, L. K., Liu, A., Briden, K. E., Tiemann, K. M., Daugherty, A. L., Hruska, K. A. & Hunstad, D. A., Nov 1 2017, In: DMM Disease Models and Mechanisms. 10, 11, p. 1371-1379 9 p.Research output: Contribution to journal › Article › peer-review
Open Access19 Scopus citations -
The chronic kidney disease — Mineral bone disorder (CKD-MBD): Advances in pathophysiology
Hruska, K. A., Sugatani, T., Agapova, O. & Fang, Y., Jul 2017, In: Bone. 100, p. 80-86 7 p.Research output: Contribution to journal › Review article › peer-review
Open Access144 Scopus citations -
2016
Androgens enhance male urinary tract infection severity in a new model
Olson, P. D., Hruska, K. A. & Hunstad, D. A., Jun 2016, In: Journal of the American Society of Nephrology. 27, 6, p. 1625-1634 10 p.Research output: Contribution to journal › Article › peer-review
Open Access59 Scopus citations -
Bone mineral density and progression of subclinical atherosclerosis in African-Americans with type 2 diabetes
Wagenknecht, L. E., Divers, J., Register, T. C., Russell, G. B., Bowden, D. W., Xu, J., Langefeld, C. D., Lenchik, L., Hruska, K. A., Carr, J. J. & Freedman, B. I., Nov 2016, In: Journal of Clinical Endocrinology and Metabolism. 101, 11, p. 4135-4141 7 p.Research output: Contribution to journal › Article › peer-review
Open Access14 Scopus citations -
Fibroblast growth factor-23 and chronic allograft injury in pediatric renal transplant recipients: A Midwest Pediatric Nephrology Consortium study
Seifert, M. E., Ashoor, I. F., Chiang, M. L., Chishti, A. S., Dietzen, D. J., Gipson, D. S., Janjua, H. S., Selewski, D. T. & Hruska, K. A., May 1 2016, In: Pediatric transplantation. 20, 3, p. 378-387 10 p.Research output: Contribution to journal › Article › peer-review
Open Access4 Scopus citations -
Ligand trap for the activin type IIA receptor protects against vascular disease and renal fibrosis in mice with chronic kidney disease
Agapova, O. A., Fang, Y., Sugatani, T., Seifert, M. E. & Hruska, K. A., 2016, In: Kidney International. 89, 6, p. 1231-1243 13 p.Research output: Contribution to journal › Article › peer-review
Open Access63 Scopus citations -
The kidney-vascular-bone axis in the chronic kidney disease-mineral bone disorder
Seifert, M. E. & Hruska, K. A., 2016, In: Transplantation. 100, 3, p. 497-505 9 p.Research output: Contribution to journal › Review article › peer-review
Open Access30 Scopus citations -
2015
Clinical phenotype of APOL1 nephropathy in young relatives of patients with end-stage renal disease
Anyaegbu, E. I., Shaw, A. S., Hruska, K. A. & Jain, S., Jun 1 2015, In: Pediatric Nephrology. 30, 6, p. 983-989 7 p.Research output: Contribution to journal › Article › peer-review
15 Scopus citations -
Disorders of Mineral and Bone Metabolism in Chronic Kidney Disease
Hruska, K. A., Seifert, M. E. & Surendran, K., 2015, Chronic Renal Disease. Elsevier Inc., p. 320-331 12 p.Research output: Chapter in Book/Report/Conference proceeding › Chapter › peer-review
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Pathophysiology of the chronic kidney disease - Mineral bone disorder
Hruska, K. A., Seifert, M. & Sugatani, T., Jul 1 2015, In: Current Opinion in Nephrology and Hypertension. 24, 4, p. 303-309 7 p.Research output: Contribution to journal › Review article › peer-review
Open Access53 Scopus citations -
Plasma FGF23 and Calcified Atherosclerotic Plaque in African Americans with Type 2 Diabetes Mellitus
Freedman, B. I., Divers, J., Russell, G. B., Palmer, N. D., Bowden, D. W., Carr, J. J., Wagenknecht, L. E., Hightower, R. C., Xu, J., Smith, S. C., Langefeld, C. D., Hruska, K. A. & Register, T. C., Dec 1 2015, In: American Journal of Nephrology. 42, 6, p. 391-401 11 p.Research output: Contribution to journal › Article › peer-review
Open Access30 Scopus citations -
SIRT6 deficiency culminates in low-turnover osteopenia
Sugatani, T., Agapova, O., Malluche, H. H. & Hruska, K. A., Dec 1 2015, In: Bone. 81, p. 168-177 10 p.Research output: Contribution to journal › Article › peer-review
Open Access34 Scopus citations -
2014
CKD-induced wingless/integration1 inhibitors and phosphorus cause the CKD-mineral and bone disorder
Fang, Y., Ginsberg, C., Seifert, M., Agapova, O., Sugatani, T., Register, T. C., Freedman, B. I., Monier-Faugere, M. C., Malluche, H. & Hruska, K. A., Aug 1 2014, In: Journal of the American Society of Nephrology. 25, 8, p. 1760-1773 14 p.Research output: Contribution to journal › Article › peer-review
Open Access141 Scopus citations -
Early chronic kidney disease-mineral bone disorder stimulates vascular calcification
Fang, Y., Ginsberg, C., Sugatani, T., Monier-Faugere, M. C., Malluche, H. & Hruska, K. A., Jan 2014, In: Kidney International. 85, 1, p. 142-150 9 p.Research output: Contribution to journal › Article › peer-review
Open Access169 Scopus citations -
Expression of DGCR8-dependent microRNAs is indispensable for osteoclastic development and bone-resorbing activity
Sugatani, T., Hildreth, B. E., Toribio, R. E., Malluche, H. H. & Hruska, K. A., Jun 2014, In: Journal of cellular biochemistry. 115, 6, p. 1043-1047 5 p.Research output: Contribution to journal › Article › peer-review
26 Scopus citations -
HDAC dependent transcriptional repression of Bmp-7 potentiates TGF-β mediated renal fibrosis in obstructive uropathy
Manson, S. R., Song, J. B., Hruska, K. A. & Austin, P. F., Jan 2014, In: Journal of Urology. 191, 1, p. 242-252 11 p.Research output: Contribution to journal › Article › peer-review
Open Access34 Scopus citations -
Left ventricular mass progression despite stable blood pressure and kidney function in stage 3 chronic kidney disease
Seifert, M. E., De Las Fuentes, L., Ginsberg, C., Rothstein, M., Dietzen, D. J., Cheng, S. C., Ross, W., Windus, D., Dávila-Román, V. G. & Hruska, K. A., Jun 2014, In: American Journal of Nephrology. 39, 5, p. 392-399 8 p.Research output: Contribution to journal › Article › peer-review
Open Access29 Scopus citations -
Sclerostin is positively associated with bone mineral density in men and women and negatively associated with carotid calcified atherosclerotic plaque in men from the African American-diabetes heart study
Register, T. C., Hruska, K. A., Divers, J., Bowden, D. W., Palmer, N. D., Carr, J. J., Wagenknecht, L. E., Hightower, R. C., Xu, J., Smith, S. C., Dietzen, D. J., Langefeld, C. D. & Freedman, B. I., Jan 2014, In: Journal of Clinical Endocrinology and Metabolism. 99, 1, p. 315-321 7 p.Research output: Contribution to journal › Article › peer-review
Open Access48 Scopus citations -
2013
Admixture mapping of coronary artery calcified plaque in African Americans with type 2 diabetes mellitus
Divers, J., Palmer, N. D., Lu, L., Register, T. C., Carr, J. J., Hicks, P. J., Hightower, R. C., Smith, S. C., Xu, J., Cox, A. J., Hruska, K. A., Bowden, D. W., Lewis, C. E., Heiss, G., Province, M. A., Borecki, I. B., Kerr, K. F., Chen, Y. D. I., Palmas, W. & Rotter, J. I. & 6 others, , Feb 2013, In: Circulation: Cardiovascular Genetics. 6, 1, p. 97-105 9 p.Research output: Contribution to journal › Review article › peer-review
Open Access39 Scopus citations -
Buyer beware! doctor be aware! Questions
Anyaegbu, E., Davis, T. K., Kniska, K., Hruska, K. & Beck, A., Sep 2013, In: Pediatric Nephrology. 28, 9, p. 1785 1 p.Research output: Contribution to journal › Comment/debate
Open Access -
Buyer beware! Doctor be aware! - Answers
Anyaegbu, E., Keefe Davis, T., Kniska, K., Hruska, K. & Beck, A., Sep 2013, In: Pediatric Nephrology. 28, 9, p. 1787-1790 4 p.Research output: Contribution to journal › Article › peer-review
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Down-regulation of miR-21 biogenesis by estrogen action contributes to osteoclastic apoptosis
Sugatani, T. & Hruska, K. A., Jun 2013, In: Journal of cellular biochemistry. 114, 6, p. 1217-1222 6 p.Research output: Contribution to journal › Article › peer-review
88 Scopus citations -
Effects of phosphate binder therapy on vascular stiffness in early-stage chronic kidney disease
Seifert, M. E., De Las Fuentes, L., Rothstein, M., Dietzen, D. J., Bierhals, A. J., Cheng, S. C., Ross, W., Windus, D., Dávila-Román, V. G. & Hruska, K. A., Aug 2013, In: American Journal of Nephrology. 38, 2, p. 158-167 10 p.Research output: Contribution to journal › Article › peer-review
Open Access64 Scopus citations -
Pathophysiology of Chronic Kidney Disease Mineral Bone Disorder (CKD-MBD)
Hruska, K. A. & Seifert, M., Jul 19 2013, Primer on the Metabolic Bone Diseases and Disorders of Mineral Metabolism: Eighth Edition. Wiley Blackwell, p. 632-639 8 p.Research output: Chapter in Book/Report/Conference proceeding › Chapter › peer-review
7 Scopus citations -
Phosphate homeostasis in CKD: Report of a scientific symposium sponsored by the national kidney foundation
Block, G. A., Ix, J. H., Ketteler, M., Martin, K. J., Thadhani, R. I., Tonelli, M., Wolf, M., Jüppner, H., Hruska, K. & Wheeler, D. C., Sep 2013, In: American Journal of Kidney Diseases. 62, 3, p. 457-473 17 p.Research output: Contribution to journal › Article › peer-review
69 Scopus citations -
Plasma Dickkopf1 (DKK1) concentrations negatively associate with atherosclerotic calcified plaque in African-Americans with type 2 diabetes
Register, T. C., Hruska, K. A., Divers, J., Bowden, D. W., Palmer, N. D., Carr, J. J., Wagenknecht, L. E., Hightower, R. C., Xu, J., Smith, S. C., Dietzen, D. J., Langefeld, C. D. & Freedman, B. I., Jan 2013, In: Journal of Clinical Endocrinology and Metabolism. 98, 1, p. E60-E65Research output: Contribution to journal › Article › peer-review
Open Access48 Scopus citations -
Relationships between serum adiponectin and bone density, adiposity and calcified atherosclerotic plaque in the african american-diabetes heart study
Register, T. C., Divers, J., Bowden, D. W., Carr, J. J., Lenchik, L., Wagenknecht, L. E., Hightower, R. C., Xu, J., Smith, S. C., Hruska, K. A., Langefeld, C. D. & Freedman, B. I., May 2013, In: Journal of Clinical Endocrinology and Metabolism. 98, 5, p. 1916-1922 7 p.Research output: Contribution to journal › Article › peer-review
Open Access24 Scopus citations -
The chronic kidney disease-mineral bone disorder (CKD-MBD) and vascular calcification
Hruska, K. A., Fang, Y. & Sugatani, T., 2013, Issues in Dialysis. Nova Science Publishers, Inc., p. 207-220 14 p.Research output: Chapter in Book/Report/Conference proceeding › Chapter › peer-review
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2012
Relationships between serum MCP-1 and subclinical kidney disease: African American-Diabetes Heart Study
Murea, M., Register, T. C., Divers, J., Bowden, D. W., Carr, J. J., Hightower, C. R., Xu, J., Smith, S. C., Hruska, K. A., Langefeld, C. D. & Freedman, B. I., 2012, In: BMC Nephrology. 13, 1, 148.Research output: Contribution to journal › Article › peer-review
Open Access24 Scopus citations -
The chronic kidney disease-mineral bone disorder (CKD-MBD) and vascular calcification
Hruska, K. A., Fang, Y. & Sugatani, T., 2012, Issues in Dialysis. Nova Science Publishers, Inc., p. 207-220 14 p.Research output: Chapter in Book/Report/Conference proceeding › Chapter › peer-review
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Traditional and targeted exome sequencing reveals common, rare and novel functional deleterious variants in RET-signaling complex in a cohort of living US patients with urinary tract malformations
Chatterjee, R., Ramos, E., Hoffman, M., Vanwinkle, J., Martin, D. R., Davis, T. K., Hoshi, M., Hmiel, S. P., Beck, A., Hruska, K., Coplen, D., Liapis, H., Mitra, R., Druley, T., Austin, P. & Jain, S., Nov 2012, In: Human genetics. 131, 11, p. 1725-1738 14 p.Research output: Contribution to journal › Article › peer-review
Open Access78 Scopus citations -
2011
A microRNA expression signature of osteoclastogenesis
Sugatani, T., Vacher, J. & Hruska, K. A., Mar 31 2011, In: Blood. 117, 13, p. 3648-3657 10 p.Research output: Contribution to journal › Article › peer-review
Open Access242 Scopus citations -
Cardiovascular risk factors in chronic kidney disease: Does phosphate qualify
Hruska, K., Mathew, S., Lund, R., Fang, Y. & Sugatani, T., Apr 2011, In: Kidney International. 79, SUPPL. 121, p. S9Research output: Contribution to journal › Review article › peer-review
Open Access42 Scopus citations -
Editorial: 50 years of research and discovery in chronic kidney disease and mineral bone disorder: The central role of phosphate
Slatopolsky, E., Moe, S., Bouillon, R., Bushinsky, D., Confavreux, C., Drueke, T., Hruska, K., Jüppner, H., Kuro-O, M., Pollak, M. & Rodriguez, M., Apr 2011, In: Kidney International. 79, SUPPL. 121, p. S1-S2Research output: Contribution to journal › Editorial
Open Access1 Scopus citations -
Endogenous BMP-7 is a critical molecular determinant of the reversibility of obstruction-induced renal injuries
Manson, S. R., Niederhoff, R. A., Hruska, K. A. & Austin, P. F., Dec 2011, In: American Journal of Physiology - Renal Physiology. 301, 6, p. F1293-F1302Research output: Contribution to journal › Article › peer-review
Open Access23 Scopus citations