• 516 Citations

Research output per year

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Personal profile

Research interests

My primary research interests are mechanisms of age- and trauma-related neurodegeneration using in vivo models to test the efficacy of novel therapeutic compounds to treat disease.

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Research Output

  • 516 Citations
  • 10 Article
  • 2 Review article

Antisense oligonucleotides extend survival and reverse decrement in muscle response in ALS models

McCampbell, A., Cole, T., Wegener, A. J., Tomassy, G. S., Setnicka, A., Farley, B. J., Schoch, K. M., Hoye, M. L., Shabsovich, M., Sun, L., Luo, Y., Zhang, M., Thankamony, S., Salzman, D. W., Cudkowicz, M., Graham, D. L., Bennett, C. F., Kordasiewicz, H. B., Swayze, E. E. & Miller, T. M., Aug 1 2018, In : Journal of Clinical Investigation. 128, 8, p. 3558-3567 10 p.

Research output: Contribution to journalArticle

Open Access
  • 44 Scopus citations

    Protein production is an early biomarker for RNA-targeted therapies

    Self, W. K., Schoch, K. M., Alex, J., Barthélemy, N., Bollinger, J. G., Sato, C., Cole, T., Kordasiewicz, H. B., Swayze, E., Bateman, R. J. & Miller, T. M., Dec 2018, In : Annals of Clinical and Translational Neurology. 5, 12, p. 1492-1504 13 p.

    Research output: Contribution to journalArticle

    Open Access
  • 2 Scopus citations

    Synthesis and in vitro characterization of a P2X7 radioligand [123I]TZ6019 and its response to neuroinflammation in a mouse model of Alzheimer disease

    Jin, H., Han, J., Resing, D., Liu, H., Yue, X., Miller, R. L., Schoch, K. M., Miller, T. M., Perlmutter, J. S., Egan, T. M. & Tu, Z., Feb 5 2018, In : European Journal of Pharmacology. 820, p. 8-17 10 p.

    Research output: Contribution to journalArticle

  • 20 Scopus citations

    Antisense Oligonucleotides: Translation from Mouse Models to Human Neurodegenerative Diseases

    Schoch, K. M. & Miller, T. M., Jun 21 2017, In : Neuron. 94, 6, p. 1056-1070 15 p.

    Research output: Contribution to journalReview article

    Open Access
  • 93 Scopus citations

    MicroRNA profiling reveals marker of motor neuron disease in ALS models

    Hoye, M. L., Koval, E. D., Wegener, A. J., Hyman, T. S., Yang, C., O’Brien, D. R., Miller, R. L., Cole, T., Schoch, K. M., Shen, T., Kunikata, T., Richard, J. P., Gutmann, D. H., Maragakis, N. J., Kordasiewicz, H. B., Dougherty, J. D. & Miller, T. M., May 31 2017, In : Journal of Neuroscience. 37, 22, p. 5574-5586 13 p.

    Research output: Contribution to journalArticle

    Open Access
  • 31 Scopus citations