Research output per year
Research output per year
- 49 results
Search results
-
2024
Microbial co-occurrences on catheters from long-term catheterized patients
Nye, T. M., Zou, Z., Obernuefemann, C. L. P., Pinkner, J. S., Lowry, E., Kleinschmidt, K., Bergeron, K., Klim, A., Dodson, K. W., Flores-Mireles, A. L., Walker, J. N., Wong, D. G., Desai, A., Caparon, M. G. & Hultgren, S. J., Dec 2024, In: Nature communications. 15, 1, 61.Research output: Contribution to journal › Article › peer-review
Open Access10 Scopus citations -
2023
Structure–function correlates of fibrinogen binding by Acinetobacter adhesins critical in catheter-associated urinary tract infections
Tamadonfar, K. O., Di Venanzio, G., Pinkner, J. S., Dodson, K. W., Kalas, V., Zimmerman, M. I., Villicana, J. B., Bowman, G. R., Feldman, M. F. & Hultgren, S. J., Jan 24 2023, In: Proceedings of the National Academy of Sciences of the United States of America. 120, 4, e2212694120.Research output: Contribution to journal › Article › peer-review
Open Access4 Scopus citations -
2022
Establishing the role of the gut microbiota in susceptibility to recurrent urinary tract infections
Worby, C. J., Olson, B. S., Dodson, K. W., Earl, A. M. & Hultgren, S. J., Mar 1 2022, In: Journal of Clinical Investigation. 132, 5, e158497.Research output: Contribution to journal › Review article › peer-review
Open Access22 Scopus citations -
Longitudinal multi-omics analyses link gut microbiome dysbiosis with recurrent urinary tract infections in women
Worby, C. J., Schreiber, H. L., Straub, T. J., van Dijk, L. R., Bronson, R. A., Olson, B. S., Pinkner, J. S., Obernuefemann, C. L. P., Muñoz, V. L., Paharik, A. E., Azimzadeh, P. N., Walker, B. J., Desjardins, C. A., Chou, W. C., Bergeron, K., Chapman, S. B., Klim, A., Manson, A. L., Hannan, T. J. & Hooton, T. M. & 5 others, , May 2022, In: Nature microbiology. 7, 5, p. 630-639 10 p.Research output: Contribution to journal › Article › peer-review
Open Access69 Scopus citations -
Ring-fused 2-pyridones effective against multidrug-resistant Gram-positive pathogens and synergistic with standard-of-care antibiotics
Nye, T. M., Tukenmez, H., Singh, P., Flores-Mireles, A. L., Obernuefemann, C. L. P., Pinkner, J. S., Sarkar, S., Bonde, M., Lindgren, A. E. G., Dodson, K. W., Johansson, J., Almqvist, F., Caparon, M. G. & Hultgren, S. J., Oct 25 2022, In: Proceedings of the National Academy of Sciences of the United States of America. 119, 43, e2210912119.Research output: Contribution to journal › Article › peer-review
Open Access8 Scopus citations -
2021
Limited effects of long-term daily cranberry consumption on the gut microbiome in a placebo-controlled study of women with recurrent urinary tract infections
Straub, T. J., Chou, W. C., Manson, A. L., Schreiber, H. L., Walker, B. J., Desjardins, C. A., Chapman, S. B., Kaspar, K. L., Kahsai, O. J., Traylor, E., Dodson, K. W., Hullar, M. A. J., Hultgren, S. J., Khoo, C. & Earl, A. M., Dec 2021, In: BMC Microbiology. 21, 1, 53.Research output: Contribution to journal › Article › peer-review
Open Access22 Scopus citations -
2020
Adaptation of arginine synthesis among uropathogenic branches of the escherichia coli phylogeny reveals adjustment to the urinary tract habitat
Hibbing, M. E., Dodson, K. W., Kalas, V., Chen, S. L. & Hultgren, S. J., Sep 1 2020, In: mBio. 11, 5, p. 1-15 15 p., e02318-20.Research output: Contribution to journal › Article › peer-review
Open Access12 Scopus citations -
2018
Functional role of the type 1 pilus rod structure in mediating host-pathogen interactions
Spaulding, C. N., Schreiber, H. L., Zheng, W., Dodson, K. W., Hazen, J. E., Conover, M. S., Wang, F., Svenmarker, P., Luna-Rico, A., Francetic, O., Andersson, M., Hultgren, S. & Egelman, E. H., Jan 18 2018, In: eLife. 7, e31662.Research output: Contribution to journal › Article › peer-review
Open Access66 Scopus citations -
Structural basis for usher activation and intramolecular subunit transfer in P pilus biogenesis in Escherichia coli
Omattage, N. S., Deng, Z., Pinkner, J. S., Dodson, K. W., Almqvist, F., Yuan, P. & Hultgren, S. J., Dec 1 2018, In: Nature microbiology. 3, 12, p. 1362-1368 7 p.Research output: Contribution to journal › Letter › peer-review
Open Access16 Scopus citations -
2017
Bacterial virulence phenotypes of Escherichia coli and host susceptibility determine risk for urinary tract infections
Schreiber, H. L., Conover, M. S., Chou, W. C., Hibbing, M. E., Manson, A. L., Dodson, K. W., Hannan, T. J., Roberts, P. L., Stapleton, A. E., Hooton, T. M., Livny, J., Earl, A. M. & Hultgren, S. J., Mar 22 2017, In: Science translational medicine. 9, 382, eaaf1283.Research output: Contribution to journal › Article › peer-review
Open Access103 Scopus citations -
Evolutionary fine-tuning of conformational ensembles in FimH during host-pathogen interactions
Kalas, V., Pinkner, J. S., Hannan, T. J., Hibbing, M. E., Dodson, K. W., Holehouse, A. S., Zhang, H., Tolia, N. H., Gross, M. L., Pappu, R. V., Janetka, J. & Hultgren, S. J., Feb 2017, In: Science Advances. 3, 2, e1601944.Research output: Contribution to journal › Article › peer-review
Open Access46 Scopus citations -
Narrowing the spectrum: The new frontier of precision antimicrobials
Paharik, A. E., Schreiber, H. L., Spaulding, C. N., Dodson, K. W. & Hultgren, S. J., Dec 14 2017, In: Genome medicine. 9, 1, 110.Research output: Contribution to journal › Comment/debate
Open Access42 Scopus citations -
One size doesn't fit all: Unraveling the diversity of factors and interactions that drive E. coli urovirulence
Schreiber, H. L., Spaulding, C. N., Dodson, K. W., Livny, J. & Hultgren, S. J., Jan 2017, In: Annals of Translational Medicine. 5, 2, 28.Research output: Contribution to journal › Editorial
Open Access11 Scopus citations -
Selective depletion of uropathogenic E. coli from the gut by a FimH antagonist
Spaulding, C. N., Klein, R. D., Ruer, S., Kau, A. L., Schreiber, H. L., Cusumano, Z. T., Dodson, K. W., Pinkner, J. S., Fremont, D. H., Janetka, J. W., Remaut, H., Gordon, J. I. & Hultgren, S. J., Jun 22 2017, In: Nature. 546, 7659, p. 528-532 5 p.Research output: Contribution to journal › Article › peer-review
Open Access216 Scopus citations -
2016
Inflammation-Induced Adhesin-Receptor Interaction Provides a Fitness Advantage to Uropathogenic E. coli during Chronic Infection
Conover, M. S., Ruer, S., Taganna, J., Kalas, V., De Greve, H., Pinkner, J. S., Dodson, K. W., Remaut, H. & Hultgren, S. J., Oct 12 2016, In: Cell Host and Microbe. 20, 4, p. 482-492 11 p.Research output: Contribution to journal › Article › peer-review
Open Access48 Scopus citations -
Metabolic requirements of Escherichia coli in intracellular bacterial communities during urinary tract infection pathogenesis
Conover, M. S., Hadjifrangiskou, M., Palermo, J. J., Hibbing, M. E., Dodson, K. W. & Hultgren, S. J., Apr 12 2016, In: mBio. 7, 2, e00104-16.Research output: Contribution to journal › Article › peer-review
Open Access87 Scopus citations -
Structure of a Chaperone-Usher Pilus Reveals the Molecular Basis of Rod Uncoiling
Hospenthal, M. K., Redzej, A., Dodson, K., Ukleja, M., Frenz, B., Rodrigues, C., Hultgren, S. J., Dimaio, F., Egelman, E. H. & Waksman, G., Jan 14 2016, In: Cell. 164, 1-2, p. 269-278 10 p.Research output: Contribution to journal › Article › peer-review
Open Access53 Scopus citations -
2015
Dysregulation of escherichia coli α-hemolysin expression alters the course of acute and persistent urinary tract infection
Nagamatsu, K., Hannan, T. J., Guest, R. L., Kostakioti, M., Hadjifrangiskou, M., Binkley, J., Dodson, K., Raivio, T. L. & Hultgren, S. J., Feb 24 2015, In: Proceedings of the National Academy of Sciences of the United States of America. 112, 8, p. E871-E880Research output: Contribution to journal › Article › peer-review
Open Access124 Scopus citations -
Establishment and characterization of UTI and CAUTI in a mouse model
Conover, M. S., Flores-Mireles, A. L., Hibbing, M. E., Dodson, K. & Hultgren, S. J., Jun 23 2015, In: Journal of Visualized Experiments. 2015, 100, e52892.Research output: Contribution to journal › Article › peer-review
Open Access35 Scopus citations -
Fueling the fire with fibers: Bacterial amyloids promote inflammatory disorders
Spaulding, C. N., Dodson, K. W., Chapman, M. R. & Hultgren, S. J., 2015, In: Cell Host and Microbe. 18, 1, p. 1-2 2 p.Research output: Contribution to journal › Short survey › peer-review
Open Access19 Scopus citations -
2014
Pilicide ec240 disrupts virulence circuits in uropathogenic Escherichia coli
Greene, S. E., Pinkner, J. S., Chorell, E., Dodson, K. W., Shaffer, C. L., Conover, M. S., Livny, J., Hadjifrangiskou, M., Almqvist, F. & Hultgren, S. J., Sep 26 2014, In: mBio. 5, 6, e02038-14.Research output: Contribution to journal › Article › peer-review
Open Access67 Scopus citations -
2013
Escherichia coli biofilms have an organized and complex extracellular matrix structure
Hung, C., Zhou, Y., Pinkner, J. S., Dodson, K. W., Crowley, J. R., Heuser, J., Chapman, M. R., Hadjifrangiskou, M., Henderson, J. P. & Hultgren, S. J., Sep 10 2013, In: mBio. 4, 5, e00645-13.Research output: Contribution to journal › Article › peer-review
Open Access188 Scopus citations -
Molecular basis of usher pore gating in Escherichia coli pilus biogenesis
Volkan, E., Kalas, V., Pinkner, J. S., Dodson, K. W., Henderson, N. S., Pham, T., Waksman, G., Delcour, A. H., Thanassi, D. G. & Hultgren, S. J., Dec 17 2013, In: Proceedings of the National Academy of Sciences of the United States of America. 110, 51, p. 20741-20746 6 p.Research output: Contribution to journal › Article › peer-review
Open Access24 Scopus citations -
Positively selected FimH residues enhance virulence during urinary tract infection by altering FimH conformation
Schwartz, D. J., Kalas, V., Pinkner, J. S., Chen, S. L., Spaulding, C. N., Dodson, K. W. & Hultgren, S. J., Sep 24 2013, In: Proceedings of the National Academy of Sciences of the United States of America. 110, 39, p. 15530-15537 8 p.Research output: Contribution to journal › Article › peer-review
Open Access96 Scopus citations -
2012
Combinatorial small-molecule therapy prevents uropathogenic Escherichia coli catheter-associated urinary tract infections in mice
Guiton, P. S., Cusumano, C. K., Kline, K. A., Dodson, K. W., Han, Z., Janetka, J. W., Henderson, J. P., Caparon, M. G. & Hultgren, S. J., Sep 2012, In: Antimicrobial agents and chemotherapy. 56, 9, p. 4738-4745 8 p.Research output: Contribution to journal › Article › peer-review
Open Access92 Scopus citations -
Domain activities of PapC usher reveal the mechanism of action of an Escherichia coli molecular machine
Volkan, E., Ford, B. A., Pinkner, J. S., Dodson, K. W., Henderson, N. S., Thanassi, D. G., Waksman, G. & Hultgren, S. J., Jun 12 2012, In: Proceedings of the National Academy of Sciences of the United States of America. 109, 24, p. 9563-9568 6 p.Research output: Contribution to journal › Article › peer-review
Open Access37 Scopus citations -
The structure of the PapD-PapGII pilin complex reveals an open and flexible p5 pocket
Ford, B., Verger, D., Dodson, K., Volkan, E., Kostakioti, M., Elam, J., Pinkner, J., Waksman, G. & Hultgren, S., Dec 2012, In: Journal of bacteriology. 194, 23, p. 6390-6397 8 p.Research output: Contribution to journal › Article › peer-review
Open Access16 Scopus citations -
2010
A tale of two pili: Assembly and function of pili in bacteria
Kline, K. A., Dodson, K. W., Caparon, M. G. & Hultgren, S. J., May 2010, In: Trends in Microbiology. 18, 5, p. 224-232 9 p.Research output: Contribution to journal › Review article › peer-review
Open Access150 Scopus citations -
Structural homology between the C-terminal domain of the PapC usher and its plug
Ford, B., Rêgo, A. T., Ragan, T. J., Pinkner, J., Dodson, K., Driscoll, P. C., Hultgren, S. & Waksman, G., Apr 2010, In: Journal of bacteriology. 192, 7, p. 1824-1831 8 p.Research output: Contribution to journal › Article › peer-review
Open Access24 Scopus citations -
The differential affinity of the usher for chaperone-subunit complexes is required for assembly of complete pili
Li, Q., Ng, T. W., Dodson, K. W., So, S. S. K., Bayle, K. M., Pinkner, J. S., Scarlata, S., Hultgren, S. J. & Thanassi, D. G., Apr 2010, In: Molecular Microbiology. 76, 1, p. 159-172 14 p.Research output: Contribution to journal › Article › peer-review
Open Access26 Scopus citations -
2009
A murine model of urinary tract infection
Hung, C. S., Dodson, K. W. & Hultgren, S. J., 2009, In: Nature Protocols. 4, 8, p. 1230-1243 14 p.Research output: Contribution to journal › Article › peer-review
Open Access240 Scopus citations -
Contribution of autolysin and sortase A during Enterococcus faecalis DNA-dependent biofilm development
Guiton, P. S., Hung, C. S., Kline, K. A., Roth, R., Kau, A. L., Hayes, E., Heuser, J., Dodson, K. W., Caparon, M. G. & Hultgren, S. J., Sep 2009, In: Infection and immunity. 77, 9, p. 3626-3638 13 p.Research output: Contribution to journal › Article › peer-review
Open Access121 Scopus citations -
2007
Adaptor function of PapF depends on donor strand exchange in P-pilus biogenesis of Escherichia coli
Lee, Y. M., Dodson, K. W. & Hultgren, S. J., Jul 2007, In: Journal of bacteriology. 189, 14, p. 5276-5283 8 p.Research output: Contribution to journal › Article › peer-review
Open Access24 Scopus citations -
2004
Intracellular bacterial communities of uropathogenic Escherichia coli in urinary tract pathogenesis
Anderson, G. G., Dodson, K. W., Hooton, T. M. & Hultgren, S. J., Sep 2004, In: Trends in Microbiology. 12, 9, p. 424-430 7 p.Research output: Contribution to journal › Review article › peer-review
155 Scopus citations -
2003
Quantitative studies of the binding of the class II PapG adhesin from uropathogenic Escherichia coli to oligosaccharides
Larsson, A., Ohlsson, J., Dodson, K. W., Hultgren, S. J., Nilsson, U. & Kihlberg, J., May 15 2003, In: Bioorganic and Medicinal Chemistry. 11, 10, p. 2255-2261 7 p.Research output: Contribution to journal › Article › peer-review
45 Scopus citations -
2002
Bacterial outer membrane ushers contain distinct targeting and assembly domains for pilus biogenesis
Thanassi, D. G., Stathopoulos, C., Dodson, K., Geiger, D. & Hultgren, S. J., Nov 2002, In: Journal of bacteriology. 184, 22, p. 6260-6269 10 p.Research output: Contribution to journal › Article › peer-review
Open Access70 Scopus citations -
2001
Structural basis of the interaction of the pyelonephritic E. coli adhesin to its human kidney receptor
Dodson, K. W., Pinkner, J. S., Rose, T., Magnusson, G., Hultgren, S. J. & Waksman, G., Jun 15 2001, In: Cell. 105, 6, p. 733-743 11 p.Research output: Contribution to journal › Article › peer-review
Open Access220 Scopus citations -
2000
Role of intestinal surfactant-like particles as a potential reservoir of uropathogenic Escherichia coli
Mahmood, A., Engle, M. J., Hultgren, S. J., Goetz, G. S., Dodson, K. & Alpers, D. H., Sep 1 2000, In: Biochimica et Biophysica Acta - General Subjects. 1523, 1, p. 49-55 7 p.Research output: Contribution to journal › Article › peer-review
18 Scopus citations -
1999
Binding of pili from uropathogenic Escherichia coli to membranes secreted by human colonocytes and enterocytes
Goetz, G. S., Mahmood, A., Hultgren, S. J., Engle, M. J., Dodson, K. & Alpers, D. H., Nov 1999, In: Infection and immunity. 67, 11, p. 6161-6163 3 p.Research output: Contribution to journal › Article › peer-review
Open Access28 Scopus citations -
Structural basis of chaperone function and pilus biogenesis
Sauer, F. G., Fütterer, K., Pinkner, J. S., Dodson, K. W., Hultgren, S. J. & Waksman, G., Aug 13 1999, In: Science. 285, 5430, p. 1058-1061 4 p.Research output: Contribution to journal › Article › peer-review
345 Scopus citations -
1998
Periplasmic chaperone recognition motif of subunits mediates quaternary interactions in the pilus
Soto, G. E., Dodson, K. W., Ogg, D., Liu, C., Heuser, J., Knight, S., Kihlberg, J., Jones, C. H. & Hultgren, S. J., Nov 2 1998, In: EMBO Journal. 17, 21, p. 6155-6167 13 p.Research output: Contribution to journal › Article › peer-review
Open Access83 Scopus citations -
1995
Molecular dissection of PapD interaction with PapG reveals two chaperone‐binding sites
Xu, Z., Jones, C. H., Haslam, D., Pinkner, J. S., Dodson, K., Kihlberg, J. & Hultgren, S. J., Jun 1995, In: Molecular Microbiology. 16, 5, p. 1011-1020 10 p.Research output: Contribution to journal › Article › peer-review
26 Scopus citations -
1994
Genetic, biochemical, and structural studies of biogenesis of adhesive pili in bacteria
Kuehn, M. J., Jacob-Dubuisson, F., Dodson, K., Slonim, L., Striker, R. & Hultgren, S. J., Jan 1 1994, In: Methods in enzymology. 236, C, p. 282-306 25 p.Research output: Contribution to journal › Article › peer-review
26 Scopus citations -
1993
Initiation of assembly and association of the structural elements of a bacterial pilus depend on two specialized tip proteins
Jacob-Dubuisson, F., Heuser, J., Dodson, K., Normark, S. & Hultgren, S., 1993, In: EMBO Journal. 12, 3, p. 837-847 11 p.Research output: Contribution to journal › Article › peer-review
122 Scopus citations -
Outer-membrane PapC molecular usher discriminately recognizes periplasmic chaperone-pilus subunit complexes
Dodson, K. W., Jacob-Dubuisson, F., Striker, R. T. & Hultgren, S. J., Apr 15 1993, In: Proceedings of the National Academy of Sciences of the United States of America. 90, 8, p. 3670-3674 5 p.Research output: Contribution to journal › Article › peer-review
178 Scopus citations -
1992
Adhesin presentation in bacteria requires molecular chaperones and ushers
Jones, C. H., Jacob-Dubuisson, F., Dodson, K., Kuehn, M., Slonim, L., Striker, R. & Hultgren, S. J., 1992, In: Infection and immunity. 60, 11, p. 4445-4451 7 p.Research output: Contribution to journal › Short survey › peer-review
42 Scopus citations -
1991
A sequence at the inside end of IS50 down regulates transposition
Dodson, K. W. & Berg, D. E., Mar 1991, In: Plasmid. 25, 2, p. 145-148 4 p.Research output: Contribution to journal › Article › peer-review
2 Scopus citations -
1989
Factors affecting transposition activity of IS50 and Tn5 ends
Dodson, K. W. & Berg, D. E., Mar 30 1989, In: Gene. 76, 2, p. 207-213 7 p.Research output: Contribution to journal › Article › peer-review
27 Scopus citations -
Saturation mutagenesis of the inside end of insertion sequence IS50
Dodson, K. W. & Berg, D. E., Dec 21 1989, In: Gene. 85, 1, p. 75-81 7 p.Research output: Contribution to journal › Article › peer-review
9 Scopus citations