Research output per year
Research output per year
- 17 results
Search results
-
2024
Cholesterol 25-hydroxylase mediates neuroinflammation and neurodegeneration in a mouse model of tauopathy
Toral-Rios, D., Long, J. M., Ulrich, J. D., Yu, J., Strickland, M. R., Han, X., Holtzman, D. M., Cashikar, A. G. & Paul, S. M., Apr 1 2024, In: Journal of Experimental Medicine. 221, 4, e20232000.Research output: Contribution to journal › Article › peer-review
Open Access5 Scopus citations -
Cognition Mediates the Association between Cerebrospinal Fluid Biomarkers of Amyloid and P-Tau and Neuropsychiatric Symptoms
Frank, B., Walsh, M., Hurley, L., Groh, J., Blennow, K., Zetterberg, H., Tripodis, Y., Budson, A. E., O'Connor, M. K., Martin, B., Weller, J., McKee, A., Qiu, W., Stein, T. D., Stern, R. A., Mez, J., Henson, R., Long, J., Aschenbrenner, A. J. & Babulal, G. M. & 3 others, , Jul 30 2024, In: Journal of Alzheimer's Disease. 100, 3, p. 1055-1073 19 p.Research output: Contribution to journal › Article › peer-review
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Lumipulse-Measured Cerebrospinal Fluid Biomarkers for the Early Detection of Alzheimer Disease
Safransky, M., Groh, J. R., Blennow, K., Zetterberg, H., Tripodis, Y., Martin, B., Weller, J., Asken, B. M., Rabinovici, G. D., Qiu, W. W. Q., Mckee, A. C., Stein, T. D., Mez, J., Henson, R. L., Long, J., Morris, J. C., Perrin, R. J., Schindler, S. E. & Alosco, M. L., Nov 4 2024, In: Neurology. 103, 11, e209866.Research output: Contribution to journal › Article › peer-review
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2023
Regulation of astrocyte lipid metabolism and ApoE secretionby the microglial oxysterol, 25-hydroxycholesterol
Cashikar, A. G., Toral-Rios, D., Timm, D., Romero, J., Strickland, M., Long, J. M., Han, X., Holtzman, D. M. & Paul, S. M., Apr 2023, In: Journal of lipid research. 64, 4, 100350.Research output: Contribution to journal › Article › peer-review
Open Access19 Scopus citations -
2022
Preclinical Alzheimer's disease biomarkers accurately predict cognitive and neuropathological outcomes
Long, J. M., Coble, D. W., Xiong, C., Schindler, S. E., Perrin, R. J., Gordon, B. A., Benzinger, T. L. S., Grant, E., Fagan, A. M., Harari, O., Cruchaga, C., Holtzman, D. M. & Morris, J. C., Dec 1 2022, In: Brain. 145, 12, p. 4506-4518 13 p.Research output: Contribution to journal › Article › peer-review
Open Access24 Scopus citations -
2021
Cognitively normal APOE ε4 carriers have specific elevation of CSF SNAP-25
for the Alzheimer's Disease Neuroimaging Initiative, Jun 2021, In: Neurobiology of Aging. 102, p. 64-72 9 p.Research output: Contribution to journal › Article › peer-review
Open Access13 Scopus citations -
2020
Select Atrophied Regions in Alzheimer disease (SARA): An improved volumetric model for identifying Alzheimer disease dementia
for the Alzheimer's Disease Neuroimaging Initiative (ADNI) and the Dominantly Inherited Alzheimer Network (DIAN), 2020, In: NeuroImage: Clinical. 26, 102248.Research output: Contribution to journal › Article › peer-review
Open Access29 Scopus citations -
2019
Microglia drive APOE-dependent neurodegeneration in a tauopathy mouse model
Shi, Y., Manis, M., Long, J., Wang, K., Sullivan, P. M., Serrano, J. R., Hoyle, R. & Holtzman, D. M., Nov 1 2019, In: Journal of Experimental Medicine. 216, 11, p. 2546-2561 16 p.Research output: Contribution to journal › Article › peer-review
Open Access258 Scopus citations -
Novel upregulation of amyloid-β precursor protein (APP) by microRNA-346 via targeting of APP mRNA 5′-untranslated region: Implications in Alzheimer’s disease
Long, J. M., Maloney, B., Rogers, J. T. & Lahiri, D. K., Mar 1 2019, In: Molecular Psychiatry. 24, 3, p. 345-363 19 p.Research output: Contribution to journal › Article › peer-review
Open Access112 Scopus citations -
2018
Autoimmune Dementia
Long, J. M. & Day, G. S., Jun 1 2018, In: Seminars in Neurology. 38, 3, p. 303-315 13 p.Research output: Contribution to journal › Article › peer-review
18 Scopus citations -
2014
Human primary mixed brain cultures: Preparation, differentiation, characterization and application to neuroscience research
Ray, B., Chopra, N., Long, J. M. & Lahiri, D. K., Sep 16 2014, In: Molecular Brain. 7, 1, 63.Research output: Contribution to journal › Article › peer-review
Open Access36 Scopus citations -
Lessons from a BACE1 inhibitor trial: Off-site but not off base
Lahiri, D. K., Maloney, B., Long, J. M. & Greig, N. H., Oct 1 2014, In: Alzheimer's and Dementia. 10, 5, p. S411-S419Research output: Contribution to journal › Article › peer-review
Open Access75 Scopus citations -
MicroRNA-339-5p down-regulates protein expression of β-site amyloid precursor protein-cleaving enzyme 1 (BACE1) in human primary brain cultures and is reduced in brain tissue specimens of alzheimer disease subjects
Long, J. M., Ray, B. & Lahiri, D. K., Feb 21 2014, In: Journal of Biological Chemistry. 289, 8, p. 5184-5198 15 p.Research output: Contribution to journal › Article › peer-review
Open Access162 Scopus citations -
2012
MicroRNA-153 physiologically inhibits expression of amyloid-β precursor protein in cultured human fetal brain cells and is dysregulated in a subset of Alzheimer disease patients
Long, J. M., Ray, B. & Lahiri, D. K., Sep 7 2012, In: Journal of Biological Chemistry. 287, 37, p. 31298-31310 13 p.Research output: Contribution to journal › Article › peer-review
Open Access179 Scopus citations -
2011
Current drug targets for modulating Alzheimer's amyloid precursor protein: Role of specific micro-RNA species
Long, J. M. & Lahiri, D. K., Aug 2011, In: Current Medicinal Chemistry. 18, 22, p. 3314-3321 8 p.Research output: Contribution to journal › Article › peer-review
27 Scopus citations -
Increased secreted Amyloid precursor protein-α (sappα) in severe Autism: Proposal of a specific, Anabolic pathway and putative biomarker
Ray, B., Long, J. M., Sokol, D. K. & Lahiri, D. K., 2011, In: PloS one. 6, 6, e20405.Research output: Contribution to journal › Article › peer-review
Open Access101 Scopus citations -
MicroRNA-101 downregulates Alzheimer's amyloid-β precursor protein levels in human cell cultures and is differentially expressed
Long, J. M. & Lahiri, D. K., Jan 28 2011, In: Biochemical and Biophysical Research Communications. 404, 4, p. 889-895 7 p.Research output: Contribution to journal › Article › peer-review
Open Access179 Scopus citations