Research output per year
Research output per year
Personal profile
Research interests
Understanding the pathophysiology of Alzheimer disease, specifically as it relates to the role of cholesterol metabolism in modulating the immune response in animal models of Alzheimer disease pathology.
Clinical interests
Dementia, cognitive disorders, memory loss, Alzheimer disease, Lewy body dementia, frontotemporal dementia, vascular cognitive impairment, hereditary dementias, geriatric neurology, and neurodegenerative diseases.
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Collaborations and top research areas from the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
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Cholesterol 25-hydroxylase mediates neuroinflammation and neurodegeneration in a mouse model of tauopathy
Toral-Rios, D., Long, J. M., Ulrich, J. D., Yu, J., Strickland, M. R., Han, X., Holtzman, D. M., Cashikar, A. G. & Paul, S. M., Apr 1 2024, In: Journal of Experimental Medicine. 221, 4, e20232000.Research output: Contribution to journal › Article › peer-review
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Cognition Mediates the Association between Cerebrospinal Fluid Biomarkers of Amyloid and P-Tau and Neuropsychiatric Symptoms
Frank, B., Walsh, M., Hurley, L., Groh, J., Blennow, K., Zetterberg, H., Tripodis, Y., Budson, A. E., O'Connor, M. K., Martin, B., Weller, J., McKee, A., Qiu, W., Stein, T. D., Stern, R. A., Mez, J., Henson, R., Long, J., Aschenbrenner, A. J. & Babulal, G. M. & 3 others, , Jul 30 2024, In: Journal of Alzheimer's Disease. 100, 3, p. 1055-1073 19 p.Research output: Contribution to journal › Article › peer-review
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Regulation of astrocyte lipid metabolism and ApoE secretionby the microglial oxysterol, 25-hydroxycholesterol
Cashikar, A. G., Toral-Rios, D., Timm, D., Romero, J., Strickland, M., Long, J. M., Han, X., Holtzman, D. M. & Paul, S. M., Apr 2023, In: Journal of lipid research. 64, 4, 100350.Research output: Contribution to journal › Article › peer-review
Open Access15 Scopus citations -
Preclinical Alzheimer's disease biomarkers accurately predict cognitive and neuropathological outcomes
Long, J. M., Coble, D. W., Xiong, C., Schindler, S. E., Perrin, R. J., Gordon, B. A., Benzinger, T. L. S., Grant, E., Fagan, A. M., Harari, O., Cruchaga, C., Holtzman, D. M. & Morris, J. C., Dec 1 2022, In: Brain. 145, 12, p. 4506-4518 13 p.Research output: Contribution to journal › Article › peer-review
Open Access21 Scopus citations -
Cognitively normal APOE ε4 carriers have specific elevation of CSF SNAP-25
for the Alzheimer's Disease Neuroimaging Initiative, Jun 2021, In: Neurobiology of Aging. 102, p. 64-72 9 p.Research output: Contribution to journal › Article › peer-review
Open Access12 Scopus citations