Jun Guo

Research Output

Research Output per year

2005 2020

• 480 Citations
• 38 Article

Research Output per year

Research Output per year

Search results

• 2020

  Adaptation of extracellular matrix to massive small bowel resection in mice

  Seiler, K. M., Goo, W. H., Zhang, Q., Courtney, C., Bajinting, A., Guo, J. & Warner, B. W., Jan 1 2020, (Accepted/In press) In : Journal of Pediatric Surgery.

  Research output: Contribution to journal › Article › peer-review

  • Extracellular Matrix
  • Peroxisome Proliferator-Activated Receptors
  • RNA
  • RNA Sequence Analysis
  • Proteins

• Alterations in pancreatic islet cell function in response to small bowel resection

  Courtney, C. M., Shyr, Z. A., Yan, Z., Onufer, E. J., Steinberger, A. E., Tecos, M. E., Barron, L. K., Guo, J., Remedi, M. S. & Warner, B. W., Jul 1 2020, In : American journal of physiology. Gastrointestinal and liver physiology. 319, 1, p. G36-G42

  Research output: Contribution to journal › Article › peer-review

  • Glucagon-Like Peptide 1
  • Islets of Langerhans
  • Insulin Secretion
  • Insulin
  • Hypertrophy

• EGFR in enterocytes & endothelium and HIF1α in enterocytes are dispensable for massive small bowel resection induced angiogenesis

  Onufer, E. J., Aladegbami, B., Imai, T., Seiler, K., Bajinting, A., Courtney, C., Sutton, S., Bustos, A., Yao, J., Yeh, C. H., Sescleifer, A., Wang, L. V., Guo, J. & Warner, B. W., Sep 2020, In : PloS one. 15, 9 September, e0236964.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • hypoxia-inducible factor 1
  • epidermal growth factor receptors
  • resection
  • Hypoxia-Inducible Factor 1
  • angiogenesis

• Patient-derived small intestinal myofibroblasts direct perfused, physiologically responsive capillary development in a microfluidic Gut-on-a-Chip Model

  Seiler, K. M., Bajinting, A., Alvarado, D. M., Traore, M. A., Binkley, M. M., Goo, W. H., Lanik, W. E., Ou, J., Ismail, U., Iticovici, M., King, C. R., VanDussen, K. L., Swietlicki, E. A., Gazit, V., Guo, J., Luke, C. J., Stappenbeck, T., Ciorba, M. A., George, S. C., Meacham, J. M. & 3 others, Rubin, D. C., Good, M. & Warner, B. W., Dec 1 2020, In : Scientific reports. 10, 1, 3842.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Microfluidics
  • Myofibroblasts
  • Precision Medicine
  • Endothelial Cells
  • Cell Culture Techniques
  2 Scopus citations
• 2019

  Single-Cell Analysis Reveals Regional Reprogramming During Adaptation to Massive Small Bowel Resection in Mice

  Seiler, K. M., Waye, S. E., Kong, W., Kamimoto, K., Bajinting, A., Goo, W. H., Onufer, E. J., Courtney, C., Guo, J., Warner, B. W. & Morris, S. A., 2019, In : CMGH. 8, 3, p. 407-426 20 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Single-Cell Analysis
  • Small Intestine
  • Enterocytes
  • Retinoids
  • SHORT syndrome
  7 Scopus citations
• 2018

  Intestinal epithelial cell-specific Raptor is essential for high fat diet-induced weight gain in mice

  Onufer, E. J., Tay, S., Barron, L. K., Courtney, C. M., Warner, B. W. & Guo, J., Nov 10 2018, In : Biochemical and Biophysical Research Communications. 505, 4, p. 1174-1179 6 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Epithelial Cells
  • Raptors
  • Nutrition
  • Mechanistic Target of Rapamycin Complex 1
  • High Fat Diet
• 2017

  Epithelial cell specific Raptor is required for initiation of type 2 mucosal immunity in small intestine

  Aladegbami, B., Barron, L., Bao, J., Colasanti, J., Erwin, C. R., Warner, B. W. & Guo, J., Dec 1 2017, In : Scientific reports. 7, 1, 5580.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Tritrichomonas
  • Raptors
  • Small Intestine
  • Epithelial Cells
  • Organoids
  7 Scopus citations

• Epithelial IGF1R is dispensable for IGF2 mediated enhanced intestinal adaptation in retinoblastoma-deficient mice

  Sun, R. C., Choi, P. M., Diaz-Miron, J. L., Sommovilla, J., Guo, J., Erwin, C. R. & Warner, B. W., Jun 2017, In : Journal of Pediatric Surgery. 52, 6, p. 1026-1030 5 p.

  Research output: Contribution to journal › Article › peer-review

  • Somatomedin Receptors
  • Retinoblastoma
  • Somatomedins
  • mouse insulin-like growth factor-1
  • Knockout Mice

• Intestinal Epithelial-Specific mTORC1 Activation Enhances Intestinal Adaptation After Small Bowel Resection

  Barron, L., Sun, R. C., Aladegbami, B., Erwin, C. R., Warner, B. W. & Guo, J., Mar 1 2017, In : CMGH. 3, 2, p. 231-244 14 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Mechanistic Target of Rapamycin Complex 1
  • Raptors
  • Paneth Cells
  • Body Weight
  • Cell Proliferation
  10 Scopus citations

• Toll-like receptor 4 is critical for the development of resection-associated hepatic steatosis

  Barron, L. K., Bao, J. W., Aladegbami, B. G., Colasanti, J. J., Guo, J., Erwin, C. R. & Warner, B. W., Jun 2017, In : Journal of Pediatric Surgery. 52, 6, p. 1014-1019 6 p.

  Research output: Contribution to journal › Article › peer-review

  • Toll-Like Receptor 4
  • Liver
  • Knockout Mice
  • Short Bowel Syndrome
  • Enterocytes
  4 Scopus citations
• 2016

  Liver steatosis induced by small bowel resection is prevented by oral vancomycin

  Barron, L. K., Gayer, C. P., Roberts, A., Golden, J. M., Aladegbami, B. G., Guo, J., Erwin, C. R. & Warner, B. W., Dec 1 2016, In : Surgery (United States). 160, 6, p. 1485-1495 11 p.

  Research output: Contribution to journal › Article › peer-review

  • Fatty Liver
  • Vancomycin
  • Short Bowel Syndrome
  • Liver Diseases
  • Bile Acids and Salts
  7 Scopus citations

• Transgenic Soybean Production of Bioactive Human Epidermal Growth Factor (EGF)

  He, Y., Schmidt, M. A., Erwin, C., Guo, J., Sun, R., Pendarvis, K., Warner, B. W. & Herman, E. M. H., Jun 2016, In : PloS one. 11, 6, e0157034.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Soybeans
  • epidermal growth factor
  • Epidermal Growth Factor
  • genetically modified organisms
  • soybeans
  12 Scopus citations
• 2015

  Both epidermal growth factor and insulin-like growth factor receptors are dispensable for structural intestinal adaptation

  Sun, R. C., Diaz-Miron, J. L., Choi, P. M., Sommovilla, J., Guo, J., Erwin, C. R. & Warner, B. W., Jun 1 2015, In : Journal of Pediatric Surgery. 50, 6, p. 943-947 5 p.

  Research output: Contribution to journal › Article › peer-review

  • Somatomedin Receptors
  • Epidermal Growth Factor
  • ErbB Receptors
  • mouse EGFR protein
  • Epithelial Cells
  7 Scopus citations

• High-Protein Diet Improves Postoperative Weight Gain After Massive Small-Bowel Resection

  Sun, R. C., Choi, P. M., Diaz-Miron, J., Sommovilla, J., Guo, J., Erwin, C. R. & Warner, B. W., 2015, In : Journal of Gastrointestinal Surgery. 19, 3, p. 451-457 7 p.

  Research output: Contribution to journal › Article › peer-review

  • High-Protein Diet
  • Weight Gain
  • Body Composition
  • Short Bowel Syndrome
  • Weights and Measures
  3 Scopus citations

• The effect of impaired angiogenesis on intestinal function following massive small bowel resection

  Diaz-Miron, J., Sun, R., Choi, P., Sommovilla, J., Guo, J., Erwin, C. R., Mei, J., Scott Worthen, G. & Warner, B. W., Jun 1 2015, In : Journal of Pediatric Surgery. 50, 6, p. 948-953 6 p.

  Research output: Contribution to journal › Article › peer-review

  • Knockout Mice
  • Fats
  • Weight Gain
  • Capillaries
  • Chemokine CXCL5
  5 Scopus citations
• 2014

  CXCL5 is required for angiogenesis, but not structural adaptation after small bowel resection

  Rowland, K. J., Diaz-Miron, J., Guo, J., Erwin, C. R., Mei, J., Worthen, G. S. & Warner, B. W., Jun 2014, In : Journal of Pediatric Surgery. 49, 6, p. 976-980 5 p.

  Research output: Contribution to journal › Article › peer-review

  • Capillaries
  • Knockout Mice
  • Chemokine CXCL5
  • Blood Vessels
  • Growth
  13 Scopus citations

• Disruption of retinoblastoma protein expression in the intestinal epithelium impairs lipid absorption

  Choi, P. M., Guo, J., Erwin, C. R., Wandu, W. S., Leinicke, J. A., Xie, Y., Davidson, N. O. & Warner, B. W., May 15 2014, In : American Journal of Physiology - Gastrointestinal and Liver Physiology. 306, 10, p. G909-G915

  Research output: Contribution to journal › Article › peer-review

  • Retinoblastoma Protein
  • Intestinal Mucosa
  • Lipids
  • Fats
  • Intestinal Absorption
  7 Scopus citations

• High-Fat Diet Enhances Villus Growth During the Adaptation Response to Massive Proximal Small Bowel Resection

  Choi, P. M., Sun, R. C., Guo, J., Erwin, C. R. & Warner, B. W., Feb 2014, In : Journal of Gastrointestinal Surgery. 18, 2, p. 286-294 9 p.

  Research output: Contribution to journal › Article › peer-review

  • High Fat Diet
  • Growth
  • Diet
  • Small Intestine
  • Fats
  20 Scopus citations

• IGF-2 Is Necessary for Retinoblastoma-Mediated Enhanced Adaptation after Small-Bowel Resection

  Choi, P. M., Sun, R. C., Sommovilla, J., Diaz-Miron, J., Guo, J., Erwin, C. R. & Warner, B. W., 2014, In : Journal of Gastrointestinal Surgery. 18, 11, p. 1887-1893 7 p.

  Research output: Contribution to journal › Article › peer-review

  • Retinoblastoma
  • Somatomedins
  • Enterocytes
  • Growth
  • Retinoblastoma Protein
  4 Scopus citations

• Insulin-like growth factor 2 and its enterocyte receptor are not required for adaptation in response to massive small bowel resection

  Sun, R. C., Choi, P. M., Guo, J., Erwin, C. R. & Warner, B. W., Jun 2014, In : Journal of Pediatric Surgery. 49, 6, p. 966-970 5 p.

  Research output: Contribution to journal › Article › peer-review

  • Enterocytes
  • Somatomedins
  • Intestines
  • Mutant Strains Mice
  • Apoptosis
  6 Scopus citations

• The role of enteral fat as a modulator of body composition after small bowel resection

  Choi, P. M., Sun, R. C., Sommovilla, J., Diaz-Miron, J., Khil, J., Erwin, C. R., Guo, J. & Warner, B. W., Aug 2014, In : Surgery (United States). 156, 2, p. 412-418 7 p.

  Research output: Contribution to journal › Article › peer-review

  • Body Composition
  • Small Intestine
  • Fats
  • Menhaden oil
  • High Fat Diet
  5 Scopus citations
• 2013

  IGF-2 mediates intestinal mucosal hyperplasia in retinoblastoma protein (Rb)-deficient mice

  Choi, P., Guo, J., Erwin, C. R. & Warner, B. W., Jun 2013, In : Journal of Pediatric Surgery. 48, 6, p. 1340-1347 8 p.

  Research output: Contribution to journal › Article › peer-review

  • Retinoblastoma Protein
  • Insulin-Like Growth Factor II
  • Enterocytes
  • Intestinal Mucosa
  • Phenotype
  10 Scopus citations
• 2012

  Deletion of p38-alpha mitogen-activated protein kinase within the intestinal epithelium promotes colon tumorigenesis

  Wakeman, D., Schneider, J. E., Liu, J., Wandu, W. S., Erwin, C. R., Guo, J., Stappenbeck, T. S. & Warner, B. W., Aug 2012, In : Surgery (United States). 152, 2, p. 286-293 8 p.

  Research output: Contribution to journal › Article › peer-review

  • Intestinal Mucosa
  • p38 Mitogen-Activated Protein Kinases
  • Colon
  • Carcinogenesis
  • villin
  22 Scopus citations

• P38 MAPK regulates Bax activity and apoptosis in enterocytes at baseline and after intestinal resection

  Wakeman, D., Guo, J., Santos, J. A., Wandu, W. S., Schneider, J. E., Mcmellen, M. E., Leinicke, J. A., Erwin, C. R. & Warner, B. W., May 1 2012, In : American Journal of Physiology - Gastrointestinal and Liver Physiology. 302, 9, p. G997-G1005

  Research output: Contribution to journal › Article › peer-review

  • Enterocytes
  • p38 Mitogen-Activated Protein Kinases
  • Apoptosis
  • Knockout Mice
  • villin
  18 Scopus citations

• Regulation of Retinoblastoma Protein (Rb) by p21 Is Critical for Adaptation to Massive Small Bowel Resection

  Leinicke, J. A., Longshore, S., Wakeman, D., Guo, J. & Warner, B. W., Jan 2012, In : Journal of Gastrointestinal Surgery. 16, 1, p. 148-155 8 p.

  Research output: Contribution to journal › Article › peer-review

  • Retinoblastoma Protein
  • Null Lymphocytes
  • Enterocytes
  • Negative Results
  • Intestines
  11 Scopus citations

• Ret heterozygous mice have enhanced intestinal adaptation after massive small bowel resection

  Hitch, M. C., Leinicke, J. A., Wakeman, D., Guo, J., Erwin, C. R., Rowland, K. J., Merrick, E. C., Heuckeroth, R. O. & Warner, B. W., May 15 2012, In : American Journal of Physiology - Gastrointestinal and Liver Physiology. 302, 10, p. G1143-G1150

  Research output: Contribution to journal › Article › peer-review

  • Enteric Nervous System
  • Enterocytes
  • Glucagon-Like Peptide 2
  • ErbB Receptors
  • Amphiregulin
  13 Scopus citations
• 2010

  Epidermal growth factor receptor signaling modulates chemokine (CXC) ligand 5 expression and is associated with villus angiogenesis after small bowel resection

  McMellen, M. E., Wakeman, D., Erwin, C. R., Guo, J. & Warner, B. W., 2010, In : Surgery. 148, 2, p. 364-370 7 p.

  Research output: Contribution to journal › Article › peer-review

  • CXC Chemokines
  • ErbB Receptors
  • Epidermal Growth Factor
  • Ligands
  • Messenger RNA
  18 Scopus citations

• Extent of small bowel resection does not influence the magnitude of intestinal adaptation in the mouse

  Wakeman, D., Longshore, S. W., McMellen, M. E., Santos, J. A., Guo, J., Erwin, C. R. & Warner, B. W., Jun 2010, In : Journal of Pediatric Surgery. 45, 6, p. 1274-1279 6 p.

  Research output: Contribution to journal › Article › peer-review

  • Ileum
  • Weight Loss
  • Apoptosis
  • Morbidity
  • Mortality
  10 Scopus citations
• 2009

  Intestinal resection induces angiogenesis within adapting intestinal villi

  Martin, C. A., Perrone, E. E., Longshore, S. W., Toste, P., Bitter, K., Nair, R., Guo, J., Erwin, C. R. & Warner, B. W., Jun 2009, In : Journal of Pediatric Surgery. 44, 6, p. 1077-1083 7 p.

  Research output: Contribution to journal › Article › peer-review

  • Capillaries
  • Growth
  • SHORT syndrome
  • Blood Vessels
  • RNA-Directed DNA Polymerase
  22 Scopus citations

• p21^waf1/cip1 deficiency does not perturb the intestinal crypt stem cell population after massive small bowel resection

  Longshore, S. W., Nair, R., Perrone, E. E., Erwin, C. R., Guo, J. & Warner, B. W., Jun 2009, In : Journal of Pediatric Surgery. 44, 6, p. 1065-1071 7 p.

  Research output: Contribution to journal › Article › peer-review

  • Stem Cells
  • Population
  • Enterocytes
  • Ileum
  • Hematopoietic Stem Cells
  6 Scopus citations

• Retinoblastoma protein (pRb), but not p107 or p130, is required for maintenance of enterocyte quiescence and differentiation in small intestine

  Guo, J., Longshore, S., Nair, R. & Warner, B. W., Jan 2 2009, In : Journal of Biological Chemistry. 284, 1, p. 134-140 7 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Retinoblastoma Protein
  • Enterocytes
  • Small Intestine
  • Epithelial Cells
  • villin
  54 Scopus citations
• 2008

  Lessons learned: optimization of a murine small bowel resection model

  Taylor, J. A., Martin, C. A., Nair, R., Guo, J., Erwin, C. R. & Warner, B. W., Jun 2008, In : Journal of Pediatric Surgery. 43, 6, p. 1018-1024 7 p.

  Research output: Contribution to journal › Article › peer-review

  • Gene Expression
  • Enteral Nutrition
  • Powders
  • Growth
  • Linear Models
  15 Scopus citations

• Resection-induced intestinal adaptation and the role of enteric smooth muscle

  Martin, C. A., Bernabe, K. Q., Taylor, J. A., Nair, R., Paul, R. J., Guo, J., Erwin, C. R. & Warner, B. W., Jun 1 2008, In : Journal of Pediatric Surgery. 43, 6, p. 1011-1017 7 p.

  Research output: Contribution to journal › Article › peer-review

  • Smooth Muscle
  • Ileum
  • mouse EGFR protein
  • Carbachol
  • Intestinal Mucosa
  14 Scopus citations
• 2007

  Epidermal growth factor receptor-directed enterocyte proliferation does not induce Wnt pathway transcription

  Taylor, J. A., Bernabe, K. Q., Guo, J. & Warner, B. W., Jun 1 2007, In : Journal of Pediatric Surgery. 42, 6, p. 981-986 6 p.

  Research output: Contribution to journal › Article › peer-review

  • Catenins
  • Enterocytes
  • Wnt Signaling Pathway
  • ErbB Receptors
  • Epidermal Growth Factor
  8 Scopus citations

• Epidermal growth factor receptor signaling modulates apoptosis via p38α MAPK-dependent activation of Bax in intestinal epithelial cells

  Sheng, G., Guo, J. & Warner, B. W., Sep 1 2007, In : American Journal of Physiology - Gastrointestinal and Liver Physiology. 293, 3, p. G599-G606

  Research output: Contribution to journal › Article › peer-review

  • p38 Mitogen-Activated Protein Kinases
  • ErbB Receptors
  • Epithelial Cells
  • Apoptosis
  • Enterocytes
  42 Scopus citations
• 2006

  Epidermal Growth Factor Receptor-Mediated Proliferation of Enterocytes Requires p21^waf1/cip1 Expression

  Sheng, G., Bernabe, K. Q., Guo, J. & Warner, B. W., Jul 2006, In : Gastroenterology. 131, 1, p. 153-164 12 p.

  Research output: Contribution to journal › Article › peer-review

  • Enterocytes
  • ErbB Receptors
  • Mitogen-Activated Protein Kinases
  • Cell Proliferation
  • Epithelial Cells
  38 Scopus citations

• Roles for p21 ^waf1/cip1 and p27 ^kip1 during the adaptation response to massive intestinal resection

  Stehr, W., Bernal, N. P., Erwin, C. R., Bernabe, K. Q., Guo, J. & Warner, B. W., May 2006, In : American Journal of Physiology - Gastrointestinal and Liver Physiology. 290, 5, p. G933-G941

  Research output: Contribution to journal › Article › peer-review

  • Enterocytes
  • Cyclin-Dependent Kinases
  • Messenger RNA
  • Cyclin-Dependent Kinase Inhibitor p21
  • Laser Capture Microdissection
  13 Scopus citations
• 2005

  Epidermal growth factor-induced rapid retinoblastoma phosphorylation at Ser⁷⁸⁰ and Ser⁷⁹⁵ is mediated by ERK1/2 in small intestine epithelial cells

  Guo, J., Sheng, G. & Warner, B. W., Oct 28 2005, In : Journal of Biological Chemistry. 280, 43, p. 35992-35998 7 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Phosphorylation
  • Epithelial Cells
  • Retinoblastoma
  • Epidermal Growth Factor
  • Small Intestine
  47 Scopus citations