Jun Guo

2024

Roles for Bile Acid Signaling and Nonsense-Mediated Ribonucleic Acid Decay in Small Bowel Resection-Associated Liver Injury

Tecos, M. E., Steinberger, A. E., Guo, J., Rubin, D. C., Davidson, N. O. & Warner, B. W., Jan 2024, In: Journal of Surgical Research. 293, p. 433-442 10 p.

Research output: Contribution to journal › Article › peer-review

Open Access

1 Scopus citations

2023

Disruption of Enterohepatic Circulation of Bile Acids Ameliorates Small Bowel Resection Associated Hepatic Injury

Tecos, M. E., Steinberger, A. E., Guo, J., Rubin, D. C., Davidson, N. O. & Warner, B. W., Jun 2023, In: Journal of Pediatric Surgery. 58, 6, p. 1074-1078 5 p.

Research output: Contribution to journal › Article › peer-review

Open Access

3 Scopus citations

Intestinal Knockout of Peroxisome Proliferator-Activated Receptor-Alpha Affects Structural Adaptation but not Liver Injury Following Massive Enterectomy

Phelps, H. M., Swanson, K. A., Steinberger, A. E., Guo, J., King, A. C., Siddappa, C. M., Davidson, N. O., Rubin, D. C. & Warner, B. W., Jun 2023, In: Journal of Pediatric Surgery. 58, 6, p. 1170-1177 8 p.

Research output: Contribution to journal › Article › peer-review

Open Access

2022

A novel maladaptive unfolded protein response as a mechanism for small bowel resection-induced liver injury

Steinberger, A. E., Tecos, M. E., Phelps, H. M., Rubin, D. C., Davidson, N. O., Guo, J. & Warner, B. W., Sep 2022, In: American Journal of Physiology - Gastrointestinal and Liver Physiology. 323, 3, p. G165-G176

Research output: Contribution to journal › Article › peer-review

Open Access

6 Scopus citations

Distal Small Bowel Resection Yields Enhanced Intestinal and Colonic Adaptation

Tecos, M. E., Steinberger, A. E., Guo, J. & Warner, B. W., May 2022, In: Journal of Surgical Research. 273, p. 100-109 10 p.

Research output: Contribution to journal › Article › peer-review

Open Access

6 Scopus citations

2020

Adaptation of extracellular matrix to massive small bowel resection in mice

Seiler, K. M., Goo, W. H., Zhang, Q., Courtney, C., Bajinting, A., Guo, J. & Warner, B. W., Jun 2020, In: Journal of Pediatric Surgery. 55, 6, p. 1107-1112 6 p.

Research output: Contribution to journal › Article › peer-review

Open Access

3 Scopus citations

Alterations in pancreatic islet cell function in response to small bowel resection

Courtney, C. M., Shyr, Z. A., Yan, Z., Onufer, E. J., Steinberger, A. E., Tecos, M. E., Barron, L. K., Guo, J., Remedi, M. S. & Warner, B. W., Jul 2020, In: American Journal of Physiology - Gastrointestinal and Liver Physiology. 319, 1, p. G36-G42

Research output: Contribution to journal › Article › peer-review

Open Access

1 Scopus citations

EGFR in enterocytes & endothelium and HIF1α in enterocytes are dispensable for massive small bowel resection induced angiogenesis

Onufer, E. J., Aladegbami, B., Imai, T., Seiler, K., Bajinting, A., Courtney, C., Sutton, S., Bustos, A., Yao, J., Yeh, C. H., Sescleifer, A., Wang, L. V., Guo, J. & Warner, B. W., Sep 2020, In: PloS one. 15, 9 September, e0236964.

Research output: Contribution to journal › Article › peer-review

Open Access

4 Scopus citations

Patient-derived small intestinal myofibroblasts direct perfused, physiologically responsive capillary development in a microfluidic Gut-on-a-Chip Model

Seiler, K. M., Bajinting, A., Alvarado, D. M., Traore, M. A., Binkley, M. M., Goo, W. H., Lanik, W. E., Ou, J., Ismail, U., Iticovici, M., King, C. R., VanDussen, K. L., Swietlicki, E. A., Gazit, V., Guo, J., Luke, C. J., Stappenbeck, T., Ciorba, M. A., George, S. C. & Meacham, J. M. & 3 others, Rubin, D. C., Good, M. & Warner, B. W., Dec 1 2020, In: Scientific reports. 10, 1, 3842.

Research output: Contribution to journal › Article › peer-review

Open Access

33 Scopus citations

2019

Single-Cell Analysis Reveals Regional Reprogramming During Adaptation to Massive Small Bowel Resection in Mice

Seiler, K. M., Waye, S. E., Kong, W., Kamimoto, K., Bajinting, A., Goo, W. H., Onufer, E. J., Courtney, C., Guo, J., Warner, B. W. & Morris, S. A., 2019, In: CMGH. 8, 3, p. 407-426 20 p.

Research output: Contribution to journal › Article › peer-review

Open Access

23 Scopus citations

2018

Intestinal epithelial cell-specific Raptor is essential for high fat diet-induced weight gain in mice

Onufer, E. J., Tay, S., Barron, L. K., Courtney, C. M., Warner, B. W. & Guo, J., Nov 10 2018, In: Biochemical and Biophysical Research Communications. 505, 4, p. 1174-1179 6 p.

Research output: Contribution to journal › Article › peer-review

Open Access

1 Scopus citations

2017

Epithelial cell specific Raptor is required for initiation of type 2 mucosal immunity in small intestine

Aladegbami, B., Barron, L., Bao, J., Colasanti, J., Erwin, C. R., Warner, B. W. & Guo, J., Dec 1 2017, In: Scientific reports. 7, 1, 5580.

Research output: Contribution to journal › Article › peer-review

Open Access

15 Scopus citations

Epithelial IGF1R is dispensable for IGF2 mediated enhanced intestinal adaptation in retinoblastoma-deficient mice

Sun, R. C., Choi, P. M., Diaz-Miron, J. L., Sommovilla, J., Guo, J., Erwin, C. R. & Warner, B. W., Jun 2017, In: Journal of Pediatric Surgery. 52, 6, p. 1026-1030 5 p.

Research output: Contribution to journal › Article › peer-review

Open Access

Intestinal Epithelial-Specific mTORC1 Activation Enhances Intestinal Adaptation After Small Bowel Resection

Barron, L., Sun, R. C., Aladegbami, B., Erwin, C. R., Warner, B. W. & Guo, J., Mar 1 2017, In: CMGH. 3, 2, p. 231-244 14 p.

Research output: Contribution to journal › Article › peer-review

Open Access

26 Scopus citations

Toll-like receptor 4 is critical for the development of resection-associated hepatic steatosis

Barron, L. K., Bao, J. W., Aladegbami, B. G., Colasanti, J. J., Guo, J., Erwin, C. R. & Warner, B. W., Jun 2017, In: Journal of Pediatric Surgery. 52, 6, p. 1014-1019 6 p.

Research output: Contribution to journal › Article › peer-review

Open Access

24 Scopus citations

2016

Liver steatosis induced by small bowel resection is prevented by oral vancomycin

Barron, L. K., Gayer, C. P., Roberts, A., Golden, J. M., Aladegbami, B. G., Guo, J., Erwin, C. R. & Warner, B. W., Dec 1 2016, In: Surgery (United States). 160, 6, p. 1485-1495 11 p.

Research output: Contribution to journal › Article › peer-review

Open Access

13 Scopus citations

Transgenic Soybean Production of Bioactive Human Epidermal Growth Factor (EGF)

He, Y., Schmidt, M. A., Erwin, C., Guo, J., Sun, R., Pendarvis, K., Warner, B. W. & Herman, E. M. H., Jun 2016, In: PloS one. 11, 6, e0157034.

Research output: Contribution to journal › Article › peer-review

Open Access

18 Scopus citations

2015

Both epidermal growth factor and insulin-like growth factor receptors are dispensable for structural intestinal adaptation

Sun, R. C., Diaz-Miron, J. L., Choi, P. M., Sommovilla, J., Guo, J., Erwin, C. R. & Warner, B. W., Jun 1 2015, In: Journal of Pediatric Surgery. 50, 6, p. 943-947 5 p.

Research output: Contribution to journal › Article › peer-review

Open Access

10 Scopus citations

High-Protein Diet Improves Postoperative Weight Gain After Massive Small-Bowel Resection

Sun, R. C., Choi, P. M., Diaz-Miron, J., Sommovilla, J., Guo, J., Erwin, C. R. & Warner, B. W., Mar 2015, In: Journal of Gastrointestinal Surgery. 19, 3, p. 451-457 7 p.

Research output: Contribution to journal › Article › peer-review

4 Scopus citations

The effect of impaired angiogenesis on intestinal function following massive small bowel resection

Diaz-Miron, J., Sun, R., Choi, P., Sommovilla, J., Guo, J., Erwin, C. R., Mei, J., Scott Worthen, G. & Warner, B. W., Jun 1 2015, In: Journal of Pediatric Surgery. 50, 6, p. 948-953 6 p.

Research output: Contribution to journal › Article › peer-review

Open Access

10 Scopus citations

2014

CXCL5 is required for angiogenesis, but not structural adaptation after small bowel resection

Rowland, K. J., Diaz-Miron, J., Guo, J., Erwin, C. R., Mei, J., Worthen, G. S. & Warner, B. W., Jun 2014, In: Journal of Pediatric Surgery. 49, 6, p. 976-980 5 p.

Research output: Contribution to journal › Article › peer-review

Open Access

19 Scopus citations

Disruption of retinoblastoma protein expression in the intestinal epithelium impairs lipid absorption

Choi, P. M., Guo, J., Erwin, C. R., Wandu, W. S., Leinicke, J. A., Xie, Y., Davidson, N. O. & Warner, B. W., May 15 2014, In: American Journal of Physiology - Gastrointestinal and Liver Physiology. 306, 10, p. G909-G915

Research output: Contribution to journal › Article › peer-review

Open Access

8 Scopus citations

High-Fat Diet Enhances Villus Growth During the Adaptation Response to Massive Proximal Small Bowel Resection

Choi, P. M., Sun, R. C., Guo, J., Erwin, C. R. & Warner, B. W., Feb 2014, In: Journal of Gastrointestinal Surgery. 18, 2, p. 286-294 9 p.

Research output: Contribution to journal › Article › peer-review

Open Access

31 Scopus citations

IGF-2 Is Necessary for Retinoblastoma-Mediated Enhanced Adaptation after Small-Bowel Resection

Choi, P. M., Sun, R. C., Sommovilla, J., Diaz-Miron, J., Guo, J., Erwin, C. R. & Warner, B. W., Nov 2014, In: Journal of Gastrointestinal Surgery. 18, 11, p. 1887-1893 7 p.

Research output: Contribution to journal › Article › peer-review

4 Scopus citations

Insulin-like growth factor 2 and its enterocyte receptor are not required for adaptation in response to massive small bowel resection

Sun, R. C., Choi, P. M., Guo, J., Erwin, C. R. & Warner, B. W., Jun 2014, In: Journal of Pediatric Surgery. 49, 6, p. 966-970 5 p.

Research output: Contribution to journal › Article › peer-review

Open Access

8 Scopus citations

The role of enteral fat as a modulator of body composition after small bowel resection

Choi, P. M., Sun, R. C., Sommovilla, J., Diaz-Miron, J., Khil, J., Erwin, C. R., Guo, J. & Warner, B. W., Aug 2014, In: Surgery (United States). 156, 2, p. 412-418 7 p.

Research output: Contribution to journal › Article › peer-review

Open Access

6 Scopus citations

2013

IGF-2 mediates intestinal mucosal hyperplasia in retinoblastoma protein (Rb)-deficient mice

Choi, P., Guo, J., Erwin, C. R. & Warner, B. W., Jun 2013, In: Journal of Pediatric Surgery. 48, 6, p. 1340-1347 8 p.

Research output: Contribution to journal › Article › peer-review

Open Access

11 Scopus citations

2012

Deletion of p38-alpha mitogen-activated protein kinase within the intestinal epithelium promotes colon tumorigenesis

Wakeman, D., Schneider, J. E., Liu, J., Wandu, W. S., Erwin, C. R., Guo, J., Stappenbeck, T. S. & Warner, B. W., Aug 2012, In: Surgery (United States). 152, 2, p. 286-293 8 p.

Research output: Contribution to journal › Article › peer-review

Open Access

30 Scopus citations

P38 MAPK regulates Bax activity and apoptosis in enterocytes at baseline and after intestinal resection

Wakeman, D., Guo, J., Santos, J. A., Wandu, W. S., Schneider, J. E., Mcmellen, M. E., Leinicke, J. A., Erwin, C. R. & Warner, B. W., May 1 2012, In: American Journal of Physiology - Gastrointestinal and Liver Physiology. 302, 9, p. G997-G1005

Research output: Contribution to journal › Article › peer-review

Open Access

28 Scopus citations

Regulation of Retinoblastoma Protein (Rb) by p21 Is Critical for Adaptation to Massive Small Bowel Resection

Leinicke, J. A., Longshore, S., Wakeman, D., Guo, J. & Warner, B. W., Jan 2012, In: Journal of Gastrointestinal Surgery. 16, 1, p. 148-155 8 p.

Research output: Contribution to journal › Article › peer-review

Open Access

13 Scopus citations

Ret heterozygous mice have enhanced intestinal adaptation after massive small bowel resection

Hitch, M. C., Leinicke, J. A., Wakeman, D., Guo, J., Erwin, C. R., Rowland, K. J., Merrick, E. C., Heuckeroth, R. O. & Warner, B. W., May 15 2012, In: American Journal of Physiology - Gastrointestinal and Liver Physiology. 302, 10, p. G1143-G1150

Research output: Contribution to journal › Article › peer-review

Open Access

14 Scopus citations

2010

Epidermal growth factor receptor signaling modulates chemokine (CXC) ligand 5 expression and is associated with villus angiogenesis after small bowel resection

McMellen, M. E., Wakeman, D., Erwin, C. R., Guo, J. & Warner, B. W., 2010, In: Surgery. 148, 2, p. 364-370 7 p.

Research output: Contribution to journal › Article › peer-review

Open Access

19 Scopus citations

Extent of small bowel resection does not influence the magnitude of intestinal adaptation in the mouse

Wakeman, D., Longshore, S. W., McMellen, M. E., Santos, J. A., Guo, J., Erwin, C. R. & Warner, B. W., Jun 2010, In: Journal of Pediatric Surgery. 45, 6, p. 1274-1279 6 p.

Research output: Contribution to journal › Article › peer-review

12 Scopus citations

2009

Intestinal resection induces angiogenesis within adapting intestinal villi

Martin, C. A., Perrone, E. E., Longshore, S. W., Toste, P., Bitter, K., Nair, R., Guo, J., Erwin, C. R. & Warner, B. W., Jun 2009, In: Journal of Pediatric Surgery. 44, 6, p. 1077-1083 7 p.

Research output: Contribution to journal › Article › peer-review

Open Access

29 Scopus citations

p21^waf1/cip1 deficiency does not perturb the intestinal crypt stem cell population after massive small bowel resection

Longshore, S. W., Nair, R., Perrone, E. E., Erwin, C. R., Guo, J. & Warner, B. W., Jun 2009, In: Journal of Pediatric Surgery. 44, 6, p. 1065-1071 7 p.

Research output: Contribution to journal › Article › peer-review

Open Access

6 Scopus citations

Retinoblastoma protein (pRb), but not p107 or p130, is required for maintenance of enterocyte quiescence and differentiation in small intestine

Guo, J., Longshore, S., Nair, R. & Warner, B. W., Jan 2 2009, In: Journal of Biological Chemistry. 284, 1, p. 134-140 7 p.

Research output: Contribution to journal › Article › peer-review

Open Access

57 Scopus citations

2008

Lessons learned: optimization of a murine small bowel resection model

Taylor, J. A., Martin, C. A., Nair, R., Guo, J., Erwin, C. R. & Warner, B. W., Jun 2008, In: Journal of Pediatric Surgery. 43, 6, p. 1018-1024 7 p.

Research output: Contribution to journal › Article › peer-review

Open Access

16 Scopus citations

Resection-induced intestinal adaptation and the role of enteric smooth muscle

Martin, C. A., Bernabe, K. Q., Taylor, J. A., Nair, R., Paul, R. J., Guo, J., Erwin, C. R. & Warner, B. W., Jun 2008, In: Journal of Pediatric Surgery. 43, 6, p. 1011-1017 7 p.

Research output: Contribution to journal › Article › peer-review

17 Scopus citations

2007

Epidermal growth factor receptor-directed enterocyte proliferation does not induce Wnt pathway transcription

Taylor, J. A., Bernabe, K. Q., Guo, J. & Warner, B. W., Jun 2007, In: Journal of Pediatric Surgery. 42, 6, p. 981-986 6 p.

Research output: Contribution to journal › Article › peer-review

8 Scopus citations

Epidermal growth factor receptor signaling modulates apoptosis via p38α MAPK-dependent activation of Bax in intestinal epithelial cells

Sheng, G., Guo, J. & Warner, B. W., Sep 1 2007, In: American Journal of Physiology - Gastrointestinal and Liver Physiology. 293, 3, p. G599-G606

Research output: Contribution to journal › Article › peer-review

43 Scopus citations

2006

Epidermal Growth Factor Receptor-Mediated Proliferation of Enterocytes Requires p21^waf1/cip1 Expression

Sheng, G., Bernabe, K. Q., Guo, J. & Warner, B. W., Jul 2006, In: Gastroenterology. 131, 1, p. 153-164 12 p.

Research output: Contribution to journal › Article › peer-review

Open Access

40 Scopus citations

Roles for p21 ^waf1/cip1 and p27 ^kip1 during the adaptation response to massive intestinal resection

Stehr, W., Bernal, N. P., Erwin, C. R., Bernabe, K. Q., Guo, J. & Warner, B. W., May 2006, In: American Journal of Physiology - Gastrointestinal and Liver Physiology. 290, 5, p. G933-G941

Research output: Contribution to journal › Article › peer-review

13 Scopus citations

2005

Epidermal growth factor-induced rapid retinoblastoma phosphorylation at Ser⁷⁸⁰ and Ser⁷⁹⁵ is mediated by ERK1/2 in small intestine epithelial cells

Guo, J., Sheng, G. & Warner, B. W., Oct 28 2005, In: Journal of Biological Chemistry. 280, 43, p. 35992-35998 7 p.

Research output: Contribution to journal › Article › peer-review

Open Access

52 Scopus citations

Phosphatidylinositol-4-kinase type II α is a component of adaptor protein-3-derived vesicles

Salazar, G., Craige, B., Wainer, B. H., Guo, J., De Camilli, P. & Faundez, V., Aug 2005, In: Molecular biology of the cell. 16, 8, p. 3692-3704 13 p.

Research output: Contribution to journal › Article › peer-review

Open Access

95 Scopus citations

2004

βIVΣ1 spectrin stabilizes the nodes of Ranvier and axon initial segments

Lacas-Gervais, S., Guo, J., Strenzke, N., Scarfone, E., Kolpe, M., Jahkel, M., De Camilli, P., Moser, T., Rasband, M. N. & Solimena, M., Sep 27 2004, In: Journal of Cell Biology. 166, 7, p. 983-990 8 p.

Research output: Contribution to journal › Article › peer-review

Open Access

122 Scopus citations

2003

Phosphatidylinositol 4-kinase type IIα is responsible for the phosphatidylinositol 4-kinase activity associated with synaptic vesicles

Guo, J., Wenk, M. R., Pellegrini, L., Onofri, F., Benfenati, F. & De Camilli, P., Apr 1 2003, In: Proceedings of the National Academy of Sciences of the United States of America. 100, 7, p. 3995-4000 6 p.

Research output: Contribution to journal › Article › peer-review

Open Access

121 Scopus citations

2002

Recruitment and regulation of phosphatidylinositol phosphate kinase type 1γ by the FERM domain of talin

Di Paolo, G., Pellegrini, L., Letinic, K., Cestra, G., Zoncu, R., Voronov, S., Chang, S., Guo, J., Wenk, M. R. & De Camilli, P., Nov 7 2002, In: Nature. 420, 6911, p. 85-89 5 p.

Research output: Contribution to journal › Article › peer-review

399 Scopus citations

2001

Dephosphorylation of β2-syntrophin and Ca²⁺/μ-calpain-mediated cleavage of ICA512 upon stimulation of insulin secretion

Ort, T., Voronov, S., Guo, J., Zawalich, K., Froehner, S. C., Zawalich, W. & Solimena, M., Aug 1 2001, In: EMBO Journal. 20, 15, p. 4013-4023 11 p.

Research output: Contribution to journal › Article › peer-review

Open Access

107 Scopus citations

Direct binding of β-arrestins to two distinct intracellular domains of the δ opioid receptor

Cen, B., Yu, Q., Guo, J., Wu, Y., Ling, K., Cheng, Z., Ma, L. & Pei, G., 2001, In: Journal of Neurochemistry. 76, 6, p. 1887-1894 8 p.

Research output: Contribution to journal › Article › peer-review

42 Scopus citations

Heterologous Activation of Protein Kinase C Stimulates Phosphorylation of δ-Opioid Receptor at Serine 344, Resulting in β-Arrestin- and Clathrin-mediated Receptor Internalization

Xiang, B., Yu, G. H., Guo, J., Chen, L., Hu, W., Pei, G. & Ma, L., Feb 16 2001, In: Journal of Biological Chemistry. 276, 7, p. 4709-4716 8 p.

Research output: Contribution to journal › Article › peer-review

Open Access

65 Scopus citations

Jun Guo

Research output

Search results