Research output per year
Research output per year
Personal profile
Research interests
I am a behavioral neuroscientist with training in molecular biology. My research interests revolve around the neurobiology and etiology of neurodevelopmental disorders. I have a strong background in the application of rodent models in behavioral assays to investigate the neurobiological mechanisms related to behavioral disruptions observed in psychiatric disorders. I am interested in determining the underlying mechanisms leading to both central and peripheral defects associated with lysosomal storage diseases (LSDs) and using that information to develop effective therapies for this class of disease.
Fingerprint
Dive into the research topics where Joshua Dearborn is active. These topic labels come from the works of this person. Together they form a unique fingerprint.
- 1 Similar Profiles
Network
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
-
Cross-species efficacy of enzyme replacement therapy for CLN1 disease in mice and sheep
Nelvagal, H. R., Eaton, S. L., Wang, S. H., Eultgen, E. M., Takahashi, K., Le, S. Q., Nesbitt, R., Dearborn, J. T., Siano, N., Puhl, A. C., Dickson, P. I., Thompson, G., Murdoch, F., Brennan, P. M., Gray, M., Greenhalgh, S. N., Tennant, P., Gregson, R., Clutton, E., Nixon, J., & 10 others, Oct 17 2022, In: Journal of Clinical Investigation. 132, 20, e163107.Research output: Contribution to journal › Article › peer-review
Open Access -
Effects of chronic cannabidiol in a mouse model of naturally occurring neuroinflammation, neurodegeneration, and spontaneous seizures
Dearborn, J. T., Nelvagal, H. R., Rensing, N. R., Takahashi, K., Hughes, S. M., Wishart, T. M., Cooper, J. D., Wong, M. & Sands, M. S., Dec 2022, In: Scientific reports. 12, 1, 11286.Research output: Contribution to journal › Article › peer-review
Open Access2 Scopus citations -
A MYT1L syndrome mouse model recapitulates patient phenotypes and reveals altered brain development due to disrupted neuronal maturation
Chen, J., Lambo, M. E., Ge, X., Dearborn, J. T., Liu, Y., McCullough, K. B., Swift, R. G., Tabachnick, D. R., Tian, L., Noguchi, K., Garbow, J. R., Constantino, J. N., Gabel, H. W., Hengen, K. B., Maloney, S. E. & Dougherty, J. D., Dec 1 2021, In: Neuron. 109, 23, p. 3775-3792.e14Research output: Contribution to journal › Article › peer-review
Open Access11 Scopus citations -
Spinal manifestations of CLN1 disease start during the early postnatal period
Nelvagal, H. R., Dearborn, J. T., Ostergaard, J. R., Sands, M. S. & Cooper, J. D., Feb 2021, In: Neuropathology and Applied Neurobiology. 47, 2, p. 251-267 17 p.Research output: Contribution to journal › Article › peer-review
Open Access7 Scopus citations -
Cell-autonomous expression of the acid hydrolase galactocerebrosidase
Mikulka, C. R., Dearborn, J. T., Benitez, B. A., Strickland, A., Liu, L., Milbrandt, J. & Sands, M. S., Apr 21 2020, In: Proceedings of the National Academy of Sciences of the United States of America. 117, 16, p. 9032-9041 10 p.Research output: Contribution to journal › Article › peer-review
Open Access7 Scopus citations