Research output per year
Research output per year
Personal profile
Research interests
Our laboratory is interested in the genetics and genomics of behavior in health and disease. We utilize a variety of techniques, including human molecular genetics, informatics, mouse behavior, in vitro neuroscience, and neuroanatomy. We are continuously developing novel methods for transgenesis, gene manipulation, and transcriptional profiling of the brain. These tools help us to develop mouse models for discovery and modeling of genetic variations based on human patient populations, in order to understand the cellular and molecular underpinnings of behavior. We are particularly focused on neurodevelopmental disorders, including the autism spectrum.
Available to Mentor:
- PhD/MSTP Students
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Collaborations and top research areas from the last five years
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Characterization of early markers of disease in the mouse model of mucopolysaccharidosis IIIB
McCullough, K. B., Titus, A., Reardon, K., Conyers, S., Dougherty, J. D., Ge, X., Garbow, J. R., Dickson, P., Yuede, C. M. & Maloney, S. E., Dec 2024, In: Journal of neurodevelopmental disorders. 16, 1, 16.Research output: Contribution to journal › Article › peer-review
Open Access -
Erratum: A MYT1L syndrome mouse model recapitulates patient phenotypes and reveals altered brain development due to disrupted neuronal maturation (Neuron (2021) 109(23) (3775–3792.e14), (S0896627321006814), (10.1016/j.neuron.2021.09.009))
Chen, J., Lambo, M. E., Ge, X., Dearborn, J. T., Liu, Y., McCullough, K. B., Swift, R. G., Tabachnick, D. R., Tian, L., Noguchi, K., Garbow, J. R., Constantino, J. N., Gabel, H. W., Hengen, K. B., Maloney, S. E. & Dougherty, J. D., Jul 3 2024, In: Neuron. 112, 13, p. 2257 1 p.Research output: Contribution to journal › Comment/debate
Open Access -
Examining Sex Differences in Autism Heritability
Sandin, S., Yip, B. H. K., Yin, W., Weiss, L. A., Dougherty, J. D., Fass, S., Constantino, J. N., Hailin, Z., Turner, T. N., Marrus, N., Gutmann, D. H., Sanders, S. J. & Christoffersson, B., Jul 3 2024, In: JAMA psychiatry. 81, 7, p. 673-680 8 p.Research output: Contribution to journal › Article › peer-review
Open Access2 Scopus citations -
Neurodevelopmental Genetic Associations Across the Translational Space-Time Continuum
Gachechiladze, M. A. & Dougherty, J. D., May 1 2024, In: Biological Psychiatry. 95, 9, p. 825-827 3 p.Research output: Contribution to journal › Comment/debate
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Pycallingcards: an integrated environment for visualizing, analyzing, and interpreting Calling Cards data
Guo, J., Zhang, W., Chen, X., Yen, A., Chen, L., Shively, C. A., Li, D., Wang, T., Dougherty, J. D. & Mitra, R. D., Feb 1 2024, In: Bioinformatics. 40, 2, btae070.Research output: Contribution to journal › Article › peer-review
Open Access