Research output per year
Research output per year
- 1 - 50 out of 159 results
Search results
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2025
Association of human leucocyte antigen loci with vaccine-induced immune thrombotic thrombocytopenia: Potential role of the interaction between platelet factor 4-derived peptides and MHC-II
Petito, E., Bury, L., Antunes Heck, L., Sadler, B., De Candia, E., Podda, G. M., Falanga, A., Stefanini, L., Boccatonda, A., Sciancalepore, P., Florio, I., Imbalzano, E., Marcucci, R., Noris, P., Panella, M., Santoro, R. C., Turi, M. C., Vaudo, G., Di Paola, J. & Rondina, M. T. & 1 others, , Jan 2025, In: British Journal of Haematology. 206, 1, p. 290-295 6 p.Research output: Contribution to journal › Article › peer-review
Open Access -
2024
A case report of an unprovoked neonatal pulmonary embolism: management strategies and cardiopulmonary complications
Cowan, A. D., Emelue, E. R., Spyropoulos, G., Thakkar, M., Paola, J. D., Glatz, A. & Rabinowitz, E. J., Nov 1 2024, In: European Heart Journal - Case Reports. 8, 11, ytae527.Research output: Contribution to journal › Article › peer-review
Open Access -
Deletion of tissue factor pathway inhibitor isoform beta or gamma, but not alpha, improves clotting in hemophilic mice
Eldem, I., Antunes-Heck, L., Subramanian, R., Lasky, N. M., Ashworth, K., Di Paola, J. & Girard, T. J., Oct 2024, In: Journal of Thrombosis and Haemostasis. 22, 10, p. 2681-2691 11 p.Research output: Contribution to journal › Article › peer-review
Open Access -
Multiomic profiling reveals metabolic alterations mediating aberrant platelet activity and inflammation in myeloproliferative neoplasms
He, F., Laranjeira, A. B. A., Kong, T., Lin, S., Ashworth, K. J., Liu, A., Lasky, N. M., Fisher, D. A. C., Cox, M. J., Fulbright, M. C., Antunes-Heck, L., Yu, L. Y., Brakhane, M., Gao, B., Sykes, S. M., D’Alessandro, A., Paola, J. D. & Oh, S. T., Feb 10 2024, In: Journal of Clinical Investigation. 134, 3, e172256.Research output: Contribution to journal › Article › peer-review
Open Access3 Scopus citations -
N-Acetyl Cysteine Prevents Arterial Thrombosis in a Dose-Dependent Manner in Vitro and in Mice
Bresette, C. A., Ashworth, K. J., Di Paola, J. & Ku, D. N., Feb 1 2024, In: Arteriosclerosis, thrombosis, and vascular biology. 44, 2, p. E39-E53Research output: Contribution to journal › Article › peer-review
2 Scopus citations -
Nanobody activator improves sensitivity of the von Willebrand factor activity assay to multimer size
Liang, Q., Parker, E. T., Dean, G., Karpen, M. S., Wu, Y., Wang, X., Di Paola, J., Maier, C. L., Meeks, S. L., Lollar, P., Sidonio, R. F. & Li, R., Jul 2024, In: Journal of Thrombosis and Haemostasis. 22, 7, p. 2052-2058 7 p.Research output: Contribution to journal › Article › peer-review
Open Access -
Next generation microfluidics: fulfilling the promise of lab-on-a-chip technologies
Gurkan, U. A., Wood, D. K., Carranza, D., Herbertson, L. H., Diamond, S. L., Du, E., Guha, S., Di Paola, J., Hines, P. C., Papautsky, I., Shevkoplyas, S. S., Sniadecki, N. J., Pamula, V. K., Sundd, P., Rizwan, A., Qasba, P. & Lam, W. A., 2024, (Accepted/In press) In: Lab on a Chip.Research output: Contribution to journal › Review article › peer-review
Open Access16 Scopus citations -
Pediatric aspects of von Willebrand disease
Sidonio, R. F. & Di Paola, J., Jan 1 2024, Textbook of von Willebrand Disease: Basic and Clinical Aspects. wiley, p. 177-183 7 p.Research output: Chapter in Book/Report/Conference proceeding › Chapter › peer-review
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Type 1 VWD classification revisited: novel insights from combined analysis of the LoVIC and WiN studies
Atiq, F., Blok, R., van Kwawegen, C. B., Doherty, D., Lavin, M., van der Bom, J. G., O'Connell, N. M., de Meris, J., Ryan, K., Schols, S. E. M., Byrne, M., Heubel-Moenen, F. C. J. I., van Galen, K. P. M., Preston, R. J. S., Cnossen, M. H., Fijnvandraat, K., Baker, R. I., Meijer, K., James, P. & Di Paola, J. & 3 others, , Apr 4 2024, In: Blood. 143, 14, p. 1414-1424 11 p.Research output: Contribution to journal › Article › peer-review
Open Access12 Scopus citations -
2023
A single F153Sβ3 mutation causes constitutive integrin αIIbβ3 activation in a variant form of Glanzmann thrombasthenia
Koukouritaki, S. B., Thinn, A. M. M., Ashworth, K. J., Fang, J., Slater, H. S., Du, L. M., Nguyen, H. T. T., Pillois, X., Nurden, A. T., Ng, C. J., Paola, J. D., Zhu, J. & Wilcox, D. A., Jul 11 2023, In: Blood Advances. 7, 13, p. 3180-3191 12 p.Research output: Contribution to journal › Article › peer-review
Open Access2 Scopus citations -
Author Correction: SVEP1 is an endogenous ligand for the orphan receptor PEAR1 (Nature Communications, (2023), 14, 1, (850), 10.1038/s41467-023-36486-0)
Elenbaas, J. S., Pudupakkam, U., Ashworth, K. J., Kang, C. J., Patel, V., Santana, K., Jung, I. H., Lee, P. C., Burks, K. H., Amrute, J. M., Mecham, R. P., Halabi, C. M., Alisio, A., Di Paola, J. & Stitziel, N. O., Dec 2023, In: Nature communications. 14, 1, 1511.Research output: Contribution to journal › Comment/debate
Open Access1 Scopus citations -
Building the foundation for a community-generated national research blueprint for inherited bleeding disorders: research priorities for mucocutaneous bleeding disorders
Sidonio,, R. F., Bryant, P. C., Di Paola, J., Hale, S., Heiman, M., Horowitz, G. S., Humphrey, C., Jaffray, J., Joyner, L. C., Kasthuri, R., Konkle, B. A., Kouides, P. A., Montgomery, R., Neeves, K., Randi, A. M., Scappe, N., Tarango, C., Tickle, K., Trapane, P. & Wang, M. & 2 others, , 2023, In: Expert Review of Hematology. 16, sup1, p. 39-54 16 p.Research output: Contribution to journal › Article › peer-review
Open Access11 Scopus citations -
Characterization of copy-number variants in a large cohort of patients with von Willebrand disease reveals a relationship between disrupted regions and disease type
Zimmerman Program Investigators, Sadler, B., Christopherson, P. A., Perry, C. L., Bellissimo, D. B., Haberichter, S. L., Haller, G., Antunes, L., Flood, V. H., Di Paola, J. & Montgomery, R. R., Oct 2023, In: Research and Practice in Thrombosis and Haemostasis. 7, 7, 102232.Research output: Contribution to journal › Article › peer-review
Open Access -
D-dimer predicts venous thromboembolism in multiple myeloma: a nested case-control study
Sanfilippo, K. M., Fiala, M. A., Feinberg, D., Tathireddy, H., Girard, T., Vij, R., Di Paola, J. & Gage, B. F., Nov 2023, In: Research and Practice in Thrombosis and Haemostasis. 7, 8, 102235.Research output: Contribution to journal › Article › peer-review
Open Access3 Scopus citations -
Enhanced VWF clearance in low VWF pathogenesis: limitations of the VWFpp/VWF:Ag ratio and clinical significance
Doherty, D., Lavin, M., Byrne, M., Nolan, M., O'Sullivan, J. M., Ryan, K., O'Connell, N. M., Haberichter, S. L., Christopherson, P. A., Di Paola, J., James, P. D. & O'Donnell, J. S., Feb 14 2023, In: Blood Advances. 7, 3, p. 302-308 7 p.Research output: Contribution to journal › Article › peer-review
Open Access9 Scopus citations -
Heterogeneity in the half-life of factor VIII concentrate in patients with hemophilia A is due to variability in the clearance of endogenous von Willebrand factor
iPATH study group, May 2023, In: Journal of Thrombosis and Haemostasis. 21, 5, p. 1123-1134 12 p.Research output: Contribution to journal › Article › peer-review
Open Access5 Scopus citations -
Peripheral blood mononuclear cell tissue factor (F3 gene) transcript levels and circulating extracellular vesicles are elevated in severe coronavirus 2019 (COVID-19) disease
Girard, T. J., Antunes, L., Zhang, N., Amrute, J. M., Subramanian, R., Eldem, I., Remy, K., Mazer, M., Erlich, E. C., Cruchaga, C., Steed, A. L., Randolph, G. J. & Di Paola, J., Mar 2023, In: Journal of Thrombosis and Haemostasis. 21, 3, p. 629-638 10 p.Research output: Contribution to journal › Article › peer-review
Open Access21 Scopus citations -
SVEP1 is an endogenous ligand for the orphan receptor PEAR1
Elenbaas, J. S., Pudupakkam, U., Ashworth, K. J., Kang, C. J., Patel, V., Santana, K., Jung, I. H., Lee, P. C., Burks, K. H., Amrute, J. M., Mecham, R. P., Halabi, C. M., Aliso, A., Di Paola, J. & Stitziel, N. O., Dec 2023, In: Nature communications. 14, 1, 850.Research output: Contribution to journal › Article › peer-review
Open Access16 Scopus citations -
What can the plasma proteome tell us about platelets and (vice versa)?
Bruzek, S., Betensky, M., Di Paola, J., Diacovo, T., Goldenberg, N. & Ignjatovic, V., 2023, In: Platelets. 34, 1, 2186707.Research output: Contribution to journal › Review article › peer-review
Open Access2 Scopus citations -
2022
Apolipoprotein A-I, elevated in trauma patients, inhibits platelet activation and decreases clot strength
Jones, W. L., Ramos, C. R., Banerjee, A., Moore, E. E., Hansen, K. C., Coleman, J. R., Kelher, M., Neeves, K. B., Silliman, C. C., Di Paola, J. & Branchford, B., 2022, In: Platelets. 33, 8, p. 1119-1131 13 p.Research output: Contribution to journal › Article › peer-review
Open Access10 Scopus citations -
Genetics of inherited thrombocytopenias
Warren, J. T. & Di Paola, J., Jun 2 2022, In: Blood. 139, 22, p. 3264-3277 14 p.Research output: Contribution to journal › Article › peer-review
Open Access17 Scopus citations -
Germline ETV6 mutation promotes inflammation and disrupts lymphoid development of early hematopoietic progenitors
Zhou, C., Uluisik, R., Rowley, J. W., David, C., Jones, C. L., Scharer, C. D., Noetzli, L., Fisher, M. H., Kirkpatrick, G. D., Bark, K., Boss, J. M., Henry, C. J., Pietras, E. M., Di Paola, J. & Porter, C. C., Aug 1 2022, In: Experimental Hematology. 112-113, p. 24-34 11 p.Research output: Contribution to journal › Article › peer-review
Open Access8 Scopus citations -
Isotopically nonstationary 13C metabolic flux analysis in resting and activated human platelets
Sake, C. L., Metcalf, A. J., Meagher, M., Di Paola, J., Neeves, K. B. & Boyle, N. R., Jan 2022, In: Metabolic Engineering. 69, p. 313-322 10 p.Research output: Contribution to journal › Article › peer-review
Open Access12 Scopus citations -
Molecular pathogenesis and heterogeneity in type 3 VWD families in U.S. Zimmerman program
the Zimmerman Program Investigators, Jul 2022, In: Journal of Thrombosis and Haemostasis. 20, 7, p. 1576-1588 13 p.Research output: Contribution to journal › Article › peer-review
Open Access12 Scopus citations -
Ristocetin dependent cofactor activity in von Willebrand disease diagnosis: Limitations of relying on a single measure
the Zimmerman Program Investigators, Oct 2022, In: Research and Practice in Thrombosis and Haemostasis. 6, 7, e12807.Research output: Contribution to journal › Article › peer-review
Open Access4 Scopus citations -
Single-cell transcriptional analysis of human endothelial colony-forming cells from patients with low VWF levels
Ng, C. J., Liu, A., Venkataraman, S., Ashworth, K. J., Baker, C. D., O'Rourke, R., Vibhakar, R., Jones, K. L. & Di Paola, J., Apr 7 2022, In: Blood. 139, 14, p. 2240-2251 12 p.Research output: Contribution to journal › Article › peer-review
Open Access13 Scopus citations -
Whole-exome analysis of adolescents with low VWF and heavy menstrual bleeding identifies novel genetic associations
Sadler, B., Minard, C. G., Haller, G., Gurnett, C. A., O'Brien, S. H., Wheeler, A., Jain, S., Sharma, M., Zia, A., Kulkarni, R., Mullins, E., Ragni, M. V., Sidonio, R., Dietrich, J. E., Kouides, P. A., Di Paola, J. & Srivaths, L., Jan 25 2022, In: Blood Advances. 6, 2, p. 420-428 9 p.Research output: Contribution to journal › Article › peer-review
Open Access4 Scopus citations -
2021
Antithrombin deficiency: A pediatric disorder
Smith, N., Warren, B. B., Smith, J., Jacobson, L., Armstrong, J., Kim, J., Di Paola, J. & Manco-Johnson, M., Jun 2021, In: Thrombosis Research. 202, p. 45-51 7 p.Research output: Contribution to journal › Article › peer-review
9 Scopus citations -
ASH ISTH NHF WFH 2021 guidelines on the diagnosis of von Willebrand disease
James, P. D., Connell, N. T., Ameer, B., Di Paola, J., Eikenboom, J., Giraud, N., Haberichter, S., Jacobs-Pratt, V., Konkle, B., McLintock, C., McRae, S., Montgomery, R. R., O'Donnell, J. S., Scappe, N., Sidonio, R., Flood, V. H., Husainat, N., Kalot, M. A. & Mustafa, R. A., 2021, In: Blood Advances. 5, 1, p. 280-300 21 p.Research output: Contribution to journal › Article › peer-review
Open Access310 Scopus citations -
Bleeding assessment tools in the diagnosis of VWD in adults and children: A systematic review and meta-analysis of test accuracy
Kalot, M. A., Husainat, N., Tayiem, S., El Alayli, A., Dimassi, A. B., Diab, O., Abughanimeh, O., Madoukh, B., Qureini, A., Ameer, B., Di Paola, J., Eikenboom, J. C. J., Jacobs-Pratt, V., McLintock, C., Montgomery, R., O'Donnell, J. S., Sidonio, R., Brignardello-Petersen, R., Flood, V. & Connell, N. T. & 2 others, , Dec 14 2021, In: Blood Advances. 5, p. 5023-5031 9 p.Research output: Contribution to journal › Review article › peer-review
Open Access7 Scopus citations -
Diagnostic approach to the patient with a suspected inherited platelet disorder: Who and how to test
Perez Botero, J. & Di Paola, J., Sep 2021, In: Journal of Thrombosis and Haemostasis. 19, 9, p. 2127-2136 10 p.Research output: Contribution to journal › Article › peer-review
Open Access6 Scopus citations -
ETV6-related thrombocytopenia and platelet dysfunction
Di Paola, J. & Fisher, M. H., 2021, In: Platelets. 32, 1, p. 141-143 3 p.Research output: Contribution to journal › Review article › peer-review
4 Scopus citations -
Interleukin-7 Reverses Lymphopenia and Improves T-Cell Function in Coronavirus Disease 2019 Patient With Inborn Error of Toll-Like Receptor 3: A Case Report
Mazer, M. B., Turnbull, I. R., Miles, S., Blood, T. M., Sadler, B., Hess, A., Botney, M. D., Martin, R. S., Bosanquet, J. P., Striker, D. A., Anand, N. S., Morre, M., Caldwell, C. C., Brakenridge, S. C., Moldawer, L. L., Di Paola, J. A., Hotchkiss, R. S. & Remy, K. E., Jul 14 2021, In: Critical Care Explorations. 3, 7, p. E0500Research output: Contribution to journal › Article › peer-review
Open Access13 Scopus citations -
Laboratory variability in the diagnosis of type 2 VWD variants
the Zimmerman Program Investigators, Jan 2021, In: Journal of Thrombosis and Haemostasis. 19, 1, p. 131-138 8 p.Research output: Contribution to journal › Article › peer-review
Open Access15 Scopus citations -
Management of elective procedures in low von Willebrand factor patients in the LoVIC study
Doherty, D., Lavin, M., O’Sullivan, J. M., Ryan, K., O’Connell, N. M., Dougall, A., Byrne, M., Rafferty, M., Doyle, M. M., Di Paola, J., James, P. D. & O’Donnell, J. S., Mar 2021, In: Journal of Thrombosis and Haemostasis. 19, 3, p. 701-710 10 p.Research output: Contribution to journal › Article › peer-review
Open Access10 Scopus citations -
Negatively charged nanoparticles of multiple materials inhibit shear-induced platelet accumulation
Griffin, M. T., Ashworth, K., Hill, N., von Behren, J., Di Paola, J. & Ku, D. N., Jul 2021, In: Nanomedicine: Nanotechnology, Biology, and Medicine. 35, 102405.Research output: Contribution to journal › Article › peer-review
4 Scopus citations -
Platelet activation contributes to hypoxia-induced inflammation
Delaney, C., Davizon-Castillo, P., Allawzi, A., Posey, J., Gandjeva, A., Neeves, K., Tuder, R. M., Di Paola, J., Stenmark, K. R. & Nozik, E. S., Mar 2021, In: American Journal of Physiology - Lung Cellular and Molecular Physiology. 320, 3, p. L413-L421Research output: Contribution to journal › Article › peer-review
Open Access36 Scopus citations -
Specifications of the variant curation guidelines for ITGA2B/ITGB3: ClinGen Platelet Disorder Variant Curation Panel
Ross, J. E., Zhang, B. M., Lee, K., Mohan, S., Branchford, B. R., Bray, P., Dugan, S. N., Freson, K., Heller, P. G., Kahr, W. H. A., Lambert, M. P., Luchtman-Jones, L., Luo, M., Botero, J. P., Rondina, M. T., Ryan, G., Westbury, S., Bergmeier, W. & Di Paola, J., Jan 26 2021, In: Blood Advances. 5, 2, p. 414-431 18 p.Research output: Contribution to journal › Article › peer-review
Open Access22 Scopus citations -
von Willebrand disease: Proposing definitions for future research
Connell, N. T., James, P. D., Brignardello-Petersen, R., Abdul-Kadir, R., Ameer, B., Arapshian, A., Couper, S., Di Paola, J., Eikenboom, J., Giraud, N., Grow, J. M., Haberichter, S., Jacobs-Pratt, V., Konkle, B. A., Kouides, P., Laffan, M., Lavin, M., Leebeek, F. W. G., McLintock, C. & McRae, S. & 12 others, , Jan 26 2021, In: Blood Advances. 5, 2, p. 565-569 5 p.Research output: Contribution to journal › Comment/debate
28 Scopus citations -
von Willebrand factor antigen levels are associated with burden of rare nonsynonymous variants in the VWF gene
Zimmerman Program Investigators, Jun 10 2021, In: Blood. 137, 23, p. 3277-3283 7 p.Research output: Contribution to journal › Article › peer-review
Open Access15 Scopus citations -
2020
A mathematical model of coagulation under flow identifies factor V as a modifier of thrombin generation in hemophilia A
Link, K. G., Stobb, M. T., Sorrells, M. G., Bortot, M., Ruegg, K., Manco-Johnson, M. J., Di Paola, J. A., Sindi, S. S., Fogelson, A. L., Leiderman, K. & Neeves, K. B., Feb 1 2020, In: Journal of Thrombosis and Haemostasis. 18, 2, p. 306-317 12 p.Research output: Contribution to journal › Article › peer-review
Open Access25 Scopus citations -
An international survey to inform priorities for new guidelines on von Willebrand disease
For the VWD working group, Jan 1 2020, In: Haemophilia. 26, 1, p. 106-116 11 p.Research output: Contribution to journal › Article › peer-review
Open Access35 Scopus citations -
ETV6 germline mutations cause HDAC3/ NCOR2 mislocalization and upregulation of interferon response genes
Fisher, M. H., Kirkpatrick, G. D., Stevens, B., Jones, C., Callaghan, M., Rajpurkar, M., Fulbright, J., Cooper, M. A., Rowley, J., Porter, C. C., Gutierrez-Hartmann, A., Jones, K., Jordan, C., Pietras, E. M. & Di Paola, J., Aug 2020, In: JCI Insight. 5, 18, e140332.Research output: Contribution to journal › Article › peer-review
Open Access19 Scopus citations -
Glanzmann thrombasthenia: Genetic basis and clinical correlates
on behalf of the ClinGen Platelet Disorder Variant Curation Expert Panel, 2020, In: Haematologica. 105, 4, p. 888-894 7 p.Research output: Contribution to journal › Review article › peer-review
Open Access89 Scopus citations -
Hemostasis vs. homeostasis: Platelets are essential for preserving vascular barrier function in the absence of injury or inflammation
Gupta, S., Konradt, C., Corken, A., Ware, J., Nieswandt, B., Di Paola, J., Yu, M., Wang, D., Nieman, M. T., Whiteheart, S. W. & Brass, L. F., Sep 29 2020, In: Proceedings of the National Academy of Sciences of the United States of America. 117, 39, p. 24316-24325 10 p.Research output: Contribution to journal › Article › peer-review
Open Access36 Scopus citations -
Hypermethioninemia leads to fatal bleeding and increased mortality in a transgenic I278T mouse model of homocystinuria
Park, I., Johnson, L. K., Cox, A., Branchford, B. R., Di Paola, J., Bublil, E. M. & Majtan, T., Aug 2020, In: Biomedicines. 8, 8, 244.Research output: Contribution to journal › Article › peer-review
Open Access6 Scopus citations -
Pathologic Shear and Elongation Rates Do Not Cause Cleavage of Von Willebrand Factor by ADAMTS13 in a Purified System
Bortot, M., Sharifi, A., Ashworth, K., Walker, F., Cox, A., Ruegg, K., Clendenen, N., Neeves, K. B., Bark, D. & Di Paola, J., Aug 1 2020, In: Cellular and Molecular Bioengineering. 13, 4, p. 379-390 12 p.Research output: Contribution to journal › Article › peer-review
Open Access8 Scopus citations -
Platelet activation in experimental murine neonatal pulmonary hypertension
Davizon-Castillo, P., Allawzi, A., Sorrells, M., Fisher, S., Baltrunaite, K., Neeves, K., Nozik-Grayck, E., DiPaola, J. & Delaney, C., Mar 1 2020, In: Physiological Reports. 8, 5, e14386.Research output: Contribution to journal › Article › peer-review
Open Access12 Scopus citations -
Platelet α-granules are required for occlusive high-shear-rate thrombosis
Kim, D. A., Ashworth, K. J., Di Paola, J. & Ku, D. N., Jul 28 2020, In: Blood Advances. 4, 14, p. 3258-3267 10 p.Research output: Contribution to journal › Article › peer-review
Open Access20 Scopus citations -
Pro-inflammatory cytokine blockade attenuates myeloid expansion in a murine model of rheumatoid arthritis
Hernandez, G., Mills, T. S., Rabe, J. L., Chavez, J. S., Kuldanek, S., Kirkpatrick, G., Noetzli, L., Jubair, W. K., Zanche, M., Myers, J. R., Stevens, B. M., Fleenor, C. J., Adane, B., Dinarello, C. A., Ashton, J., Jordan, C. T., Paola, J. D., Hagman, J. R., Michael Holers, V. & Kuhn, K. A. & 1 others, , Mar 1 2020, In: Haematologica. 105, 3, p. 585-597 13 p.Research output: Contribution to journal › Article › peer-review
Open Access36 Scopus citations