Research output per year
Research output per year
Personal profile
Research interests
My focus is on myeloid development and leukemic dysregulation of self-renewal program. Current projects explore the early reprogramming of myeloid differentation by PML-RARA and RARA haploinsufficiency that result from the t(15;17) translocation associated with APL.
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Focal disruption of DNA methylation dynamics at enhancers in IDH-mutant AML cells
Wilson, E. R., Helton, N. M., Heath, S. E., Fulton, R., Payton, J. E., Welch, J., Walter, M., Westervelt, P., DiPersio, J. F., Link, D. C., Miller, C., Ley, T. J. & Spencer, D., Apr 2022, In: Leukemia. 36, 4, p. 935-945 11 p.Research output: Contribution to journal › Article › peer-review
Open Access1 Scopus citations -
Recurrent transcriptional responses in AML and MDS patients treated with decitabine
Upadhyay, P., Beales, J., Shah, N. M., Gruszczynska, A., Miller, C. A., Petti, A. A., Ramakrishnan, S. M., Link, D. C., Ley, T. J. & Welch, J. S., Jul 2022, In: Experimental Hematology. 111, p. 50-65 16 p.Research output: Contribution to journal › Article › peer-review
Open Access -
RXRA DT448/9PP generates a dominant active variant capable of inducing maturation in acute myeloid leukemia cells
di Martino, O., Ferris, M. A., Hadwiger, G., Sarkar, S., Vu, A., Menéndez-Gutiérrez, M. P., Ricote, M. & Welch, J. S., Feb 2022, In: Haematologica. 107, 2, p. 417-426 10 p.Research output: Contribution to journal › Article › peer-review
Open Access1 Scopus citations -
Cytokine exposure mediates transcriptional activation of the orphan nuclear receptor Nur77 in hematopoietic cells
Martino, O. D., Niu, H., Hadwiger, G., Ferris, M. A. & Welch, J. S., Nov 1 2021, In: Journal of Biological Chemistry. 297, 5, 101240.Research output: Contribution to journal › Article › peer-review
Open Access -
Endogenous and combination retinoids are active in myelomonocytic leukemias
di Martino, O., Niu, H., Hadwiger, G., Kuusanmaki, H., Ferris, M. A., Vu, A., Beales, J., Wagner, C., Menéndez-Gutiérrez, M. P., Ricote, M., Heckman, C. & Welch, J. S., Apr 2021, In: Haematologica. 106, 4, p. 1008-1021 14 p.Research output: Contribution to journal › Article › peer-review
Open Access7 Scopus citations