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  • 2023

    Changes over time in endorsement of 11 DSM-IV alcohol use disorder (AUD) criteria in young adults with persistent or recurrent AUD in The Collaborative Study on the Genetics of Alcoholism

    The Collaborative Study on the Genetics of Alcoholism (COGA), May 2023, In: Alcohol: Clinical and Experimental Research. 47, 5, p. 919-929 11 p.

    Research output: Contribution to journalArticlepeer-review

    1 Scopus citations
  • Genetic nurture effects for alcohol use disorder

    COGA Collaborators, Thomas, N. S., Salvatore, J. E., Kuo, S. I. C., Aliev, F., McCutcheon, V. V., Meyers, J. M., Bucholz, K. K., Brislin, S. J., Chan, G., Edenberg, H. J., Kamarajan, C., Kramer, J. R., Kuperman, S., Pandey, G., Plawecki, M. H., Schuckit, M. A., Dick, D. M., Porjesz, B., Hesselbrock, V., & 12 othersForoud, T., Agrawal, A., Liu, Y., Pandey, A., Bierut, L., Rice, J., Tischfield, J., Hart, R., Almasy, L., Goate, A., Slesinger, P. & Scott, D., Feb 2023, In: Molecular Psychiatry. 28, 2, p. 759-766 8 p.

    Research output: Contribution to journalArticlepeer-review

    5 Scopus citations
  • Genetics of vegetarianism: A genome-wide association study

    Yaseen, N. R., Barnes, C. L. K., Sun, L., Takeda, A. & Rice, J. P., Oct 2023, In: PloS one. 18, 10 October, e0291305.

    Research output: Contribution to journalArticlepeer-review

    Open Access
  • Identification of PROK2 gene polymorphisms as predictors of methamphetamine use disorder risk and indicators of craving scale in the Chinese Han population

    Jiang, Z., Zhang, T., Han, W., Xiao, J., Zhang, W., Wang, X., Liu, J., Yang, Y., Yang, C., Guan, F., Li, T. & Rice, J. P., 2023, In: Frontiers in Pharmacology. 14, 1217382.

    Research output: Contribution to journalArticlepeer-review

    Open Access
  • Polygenic risk prediction: why and when out-of-sample prediction R2 can exceed SNP-based heritability

    Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium, Jul 6 2023, In: American journal of human genetics. 110, 7, p. 1207-1215 9 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    1 Scopus citations
  • The Relationship of Attention-Deficit/Hyperactivity Disorder With Posttraumatic Stress Disorder: A Two-Sample Mendelian Randomization and Population-Based Sibling Comparison Study

    Post-Traumatic Stress Disorder Working Group of the Psychiatric Genomics Consortium, Feb 15 2023, In: Biological Psychiatry. 93, 4, p. 362-369 8 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    9 Scopus citations
  • 2022

    Dissecting the Shared Genetic Architecture of Suicide Attempt, Psychiatric Disorders, and Known Risk Factors

    Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium, Bipolar Disorder Working Group of the Psychiatric Genomics Consortium, Eating Disorders Working Group of the Psychiatric Genomics Consortium, German Borderline Genomics Consortium, MVP Suicide Exemplar Workgroup & VA Million Veteran Program, Feb 1 2022, In: Biological Psychiatry. 91, 3, p. 313-327 15 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    79 Scopus citations
  • Enhancing Discovery of Genetic Variants for Posttraumatic Stress Disorder Through Integration of Quantitative Phenotypes and Trauma Exposure Information

    Maihofer, A. X., Choi, K. W., Coleman, J. R. I., Daskalakis, N. P., Denckla, C. A., Ketema, E., Morey, R. A., Polimanti, R., Ratanatharathorn, A., Torres, K., Wingo, A. P., Zai, C. C., Aiello, A. E., Almli, L. M., Amstadter, A. B., Andersen, S. B., Andreassen, O. A., Arbisi, P. A., Ashley-Koch, A. E., Austin, S. B., & 161 othersAvdibegović, E., Borglum, A. D., Babić, D., Bækvad-Hansen, M., Baker, D. G., Beckham, J. C., Bierut, L. J., Bisson, J. I., Boks, M. P., Bolger, E. A., Bradley, B., Brashear, M., Breen, G., Bryant, R. A., Bustamante, A. C., Bybjerg-Grauholm, J., Calabrese, J. R., Caldas-de-Almeida, J. M., Chen, C. Y., Dale, A. M., Dalvie, S., Deckert, J., Delahanty, D. L., Dennis, M. F., Disner, S. G., Domschke, K., Duncan, L. E., Džubur Kulenović, A., Erbes, C. R., Evans, A., Farrer, L. A., Feeny, N. C., Flory, J. D., Forbes, D., Franz, C. E., Galea, S., Garrett, M. E., Gautam, A., Gelaye, B., Gelernter, J., Geuze, E., Gillespie, C. F., Goçi, A., Gordon, S. D., Guffanti, G., Hammamieh, R., Hauser, M. A., Heath, A. C., Hemmings, S. M. J., Hougaard, D. M., Jakovljević, M., Jett, M., Johnson, E. O., Jones, I., Jovanovic, T., Qin, X. J., Karstoft, K. I., Kaufman, M. L., Kessler, R. C., Khan, A., Kimbrel, N. A., King, A. P., Koen, N., Kranzler, H. R., Kremen, W. S., Lawford, B. R., Lebois, L. A. M., Lewis, C., Liberzon, I., Linnstaedt, S. D., Logue, M. W., Lori, A., Lugonja, B., Luykx, J. J., Lyons, M. J., Maples-Keller, J. L., Marmar, C., Martin, N. G., Maurer, D., Mavissakalian, M. R., McFarlane, A., McGlinchey, R. E., McLaughlin, K. A., McLean, S. A., Mehta, D., Mellor, R., Michopoulos, V., Milberg, W., Miller, M. W., Morris, C. P., Mors, O., Mortensen, P. B., Nelson, E. C., Nordentoft, M., Norman, S. B., O'Donnell, M., Orcutt, H. K., Panizzon, M. S., Peters, E. S., Peterson, A. L., Peverill, M., Pietrzak, R. H., Polusny, M. A., Rice, J. P., Risbrough, V. B., Roberts, A. L., Rothbaum, A. O., Rothbaum, B. O., Roy-Byrne, P., Ruggiero, K. J., Rung, A., Rutten, B. P. F., Saccone, N. L., Sanchez, S. E., Schijven, D., Seedat, S., Seligowski, A. V., Seng, J. S., Sheerin, C. M., Silove, D., Smith, A. K., Smoller, J. W., Sponheim, S. R., Stein, D. J., Stevens, J. S., Teicher, M. H., Thompson, W. K., Trapido, E., Uddin, M., Ursano, R. J., van den Heuvel, L. L., Van Hooff, M., Vermetten, E., Vinkers, C. H., Voisey, J., Wang, Y., Wang, Z., Werge, T., Williams, M. A., Williamson, D. E., Winternitz, S., Wolf, C., Wolf, E. J., Yehuda, R., Young, K. A., Young, R. M. D., Zhao, H., Zoellner, L. A., Haas, M., Lasseter, H., Provost, A. C., Salem, R. M., Sebat, J., Shaffer, R. A., Wu, T., Ripke, S., Daly, M. J., Ressler, K. J., Koenen, K. C., Stein, M. B. & Nievergelt, C. M., Apr 1 2022, In: Biological Psychiatry. 91, 7, p. 626-636 11 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    15 Scopus citations
  • Evaluation of Adenosine A2A receptor gene polymorphisms as risk factors of methamphetamine use disorder susceptibility and predictors of craving degree

    Wang, H., Ma, Y., Wang, X., Zhang, W., Han, W., Liu, H., Li, M., Xiao, J., Wei, H., Wang, C., Sindhwani, S., Zhang, T., Guan, F. & Rice, J. P., Oct 2022, In: Psychiatry Research. 316, 114790.

    Research output: Contribution to journalArticlepeer-review

    6 Scopus citations
  • Genetic diversity fuels gene discovery for tobacco and alcohol use

    23andMe Research Team, the BioBank Japan Project, Gu, C. C., Rice, J. P., Saccone, N. L. & Bierut, L. J., Dec 22 2022, In: Nature. 612, 7941, p. 720-724 5 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    54 Scopus citations
  • High Polygenic Risk Scores Are Associated With Early Age of Onset of Alcohol Use Disorder in Adolescents and Young Adults at Risk

    Collaborative Study on the Genetics of Alcoholism, Oct 2022, In: Biological Psychiatry Global Open Science. 2, 4, p. 379-388 10 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    3 Scopus citations
  • Identifying the Common Genetic Basis of Antidepressant Response

    GSRD Consortium & Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium, Apr 2022, In: Biological Psychiatry Global Open Science. 2, 2, p. 115-126 12 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    27 Scopus citations
  • Parsing genetically influenced risk pathways: genetic loci impact problematic alcohol use via externalizing and specific risk

    COGA Collaborators, Dec 2022, In: Translational psychiatry. 12, 1, 420.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    5 Scopus citations
  • Psychological trauma and the genetic overlap between posttraumatic stress disorder and major depressive disorder

    The Million Veteran Program, Post Traumatic Stress Disorder Working Group of the Psychiatric Genomics Consortium, Rice, J. P., Bierut, L. J., Saccone, N. L., Heath, A. C. & Nelson, E. C., Dec 4 2022, In: Psychological medicine. 52, 16, p. 3975-3984 10 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    7 Scopus citations
  • Sex-Dependent Shared and Nonshared Genetic Architecture Across Mood and Psychotic Disorders

    Schizophrenia Working Group of the Psychiatric Genomics Consortium, Bipolar Disorder Working Group of the Psychiatric Genomics Consortium, Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium, Sex Differences Cross-Disorder Analysis Group of the Psychiatric Genomics Consortium & iPSYCH, Jan 1 2022, In: Biological Psychiatry. 91, 1, p. 102-117 16 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    43 Scopus citations
  • Uncovering the genetic architecture of broad antisocial behavior through a genome-wide association study meta-analysis

    COGA Consortium, Spit for Science Working Group, Agrawal, A., Bierut, L., Rice, J. & Bucholz, K. K., Nov 2022, In: Molecular Psychiatry. 27, 11, p. 4453-4463 11 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    14 Scopus citations
  • 2021

    A Comparison of Ten Polygenic Score Methods for Psychiatric Disorders Applied Across Multiple Cohorts

    Schizophrenia Working Group of the Psychiatric Genomics Consortium & Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium, Nov 1 2021, In: Biological Psychiatry. 90, 9, p. 611-620 10 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    73 Scopus citations
  • Association of polygenic score for major depression with response to lithium in patients with bipolar disorder

    Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium, Jun 1 2021, In: Molecular Psychiatry. 26, 6, p. 2457-2470 14 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    34 Scopus citations
  • Bipolar multiplex families have an increased burden of common risk variants for psychiatric disorders

    Bipolar Disorder Working Group of the Psychiatric Genomics Consortium & Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium, Apr 1 2021, In: Molecular Psychiatry. 26, 4, p. 1286-1298 13 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    23 Scopus citations
  • Genome-wide association study of more than 40,000 bipolar disorder cases provides new insights into the underlying biology

    HUNT All-In Psychiatry, Jun 2021, In: Nature Genetics. 53, 6, p. 817-829 13 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    398 Scopus citations
  • Model-based assessment of replicability for genome-wide association meta-analysis

    GWAS and Sequencing Consortium of Alcohol and Nicotine Use (GSCAN), Dec 1 2021, In: Nature communications. 12, 1, 1964.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    15 Scopus citations
  • Multi-omics integration analysis identifies novel genes for alcoholism with potential overlap with neurodegenerative diseases

    The Collaborative Study on the Genetics of Alcoholism (COGA), Dec 1 2021, In: Nature communications. 12, 1, 5071.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    27 Scopus citations
  • Multivariate analysis of 1.5 million people identifies genetic associations with traits related to self-regulation and addiction

    COGA Collaborators, Oct 2021, In: Nature neuroscience. 24, 10, p. 1367-1376 10 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    96 Scopus citations
  • Shared genetic risk between eating disorder- and substance-use-related phenotypes: Evidence from genome-wide association studies

    Munn-Chernoff, M. A., Johnson, E. C., Chou, Y. L., Coleman, J. R. I., Thornton, L. M., Walters, R. K., Yilmaz, Z., Baker, J. H., Hübel, C., Gordon, S., Medland, S. E., Watson, H. J., Gaspar, H. A., Bryois, J., Hinney, A., Leppä, V. M., Mattheisen, M., Ripke, S., Yao, S., Giusti-Rodríguez, P., & 332 othersHanscombe, K. B., Adan, R. A. H., Alfredsson, L., Ando, T., Andreassen, O. A., Berrettini, W. H., Boehm, I., Boni, C., Boraska Perica, V., Buehren, K., Burghardt, R., Cassina, M., Cichon, S., Clementi, M., Cone, R. D., Courtet, P., Crow, S., Crowley, J. J., Danner, U. N., Davis, O. S. P., de Zwaan, M., Dedoussis, G., Degortes, D., DeSocio, J. E., Dick, D. M., Dikeos, D., Dina, C., Dmitrzak-Weglarz, M., Docampo, E., Duncan, L. E., Egberts, K., Ehrlich, S., Escaramís, G., Esko, T., Estivill, X., Farmer, A., Favaro, A., Fernández-Aranda, F., Fichter, M. M., Fischer, K., Föcker, M., Foretova, L., Forstner, A. J., Forzan, M., Franklin, C. S., Gallinger, S., Giegling, I., Giuranna, J., Gonidakis, F., Gorwood, P., Gratacos Mayora, M., Guillaume, S., Guo, Y., Hakonarson, H., Hatzikotoulas, K., Hauser, J., Hebebrand, J., Helder, S. G., Herms, S., Herpertz-Dahlmann, B., Herzog, W., Huckins, L. M., Hudson, J. I., Imgart, H., Inoko, H., Janout, V., Jiménez-Murcia, S., Julià, A., Kalsi, G., Kaminská, D., Karhunen, L., Karwautz, A., Kas, M. J. H., Kennedy, J. L., Keski-Rahkonen, A., Kiezebrink, K., Kim, Y. R., Klump, K. L., Knudsen, G. P. S., La Via, M. C., Le Hellard, S., Levitan, R. D., Li, D., Lilenfeld, L., Lin, B. D., Lissowska, J., Luykx, J., Magistretti, P. J., Maj, M., Mannik, K., Marsal, S., Marshall, C. R., Mattingsdal, M., McDevitt, S., McGuffin, P., Metspalu, A., Meulenbelt, I., Micali, N., Mitchell, K., Monteleone, A. M., Monteleone, P., Nacmias, B., Navratilova, M., Ntalla, I., O'Toole, J. K., Ophoff, R. A., Padyukov, L., Palotie, A., Pantel, J., Papezova, H., Pinto, D., Rabionet, R., Raevuori, A., Ramoz, N., Reichborn-Kjennerud, T., Ricca, V., Ripatti, S., Ritschel, F., Roberts, M., Rotondo, A., Rujescu, D., Rybakowski, F., Santonastaso, P., Scherag, A., Scherer, S. W., Schmidt, U., Schork, N. J., Schosser, A., Seitz, J., Slachtova, L., Slagboom, P. E., Slof-Op't Landt, M. C. T., Slopien, A., Sorbi, S., Świątkowska, B., Szatkiewicz, J. P., Tachmazidou, I., Tenconi, E., Tortorella, A., Tozzi, F., Treasure, J., Tsitsika, A., Tyszkiewicz-Nwafor, M., Tziouvas, K., van Elburg, A. A., van Furth, E. F., Wagner, G., Walton, E., Widen, E., Zeggini, E., Zerwas, S., Zipfel, S., Bergen, A. W., Boden, J. M., Brandt, H., Crawford, S., Halmi, K. A., Horwood, L. J., Johnson, C., Kaplan, A. S., Kaye, W. H., Mitchell, J., Olsen, C. M., Pearson, J. F., Pedersen, N. L., Strober, M., Werge, T., Whiteman, D. C., Woodside, D. B., Grove, J., Henders, A. K., Larsen, J. T., Parker, R., Petersen, L. V., Jordan, J., Kennedy, M. A., Birgegård, A., Lichtenstein, P., Norring, C., Landén, M., Mortensen, P. B., Polimanti, R., McClintick, J. N., Adkins, A. E., Aliev, F., Bacanu, S. A., Batzler, A., Bertelsen, S., Biernacka, J. M., Bigdeli, T. B., Chen, L. S., Clarke, T. K., Degenhardt, F., Docherty, A. R., Edwards, A. C., Foo, J. C., Fox, L., Frank, J., Hack, L. M., Hartmann, A. M., Hartz, S. M., Heilmann-Heimbach, S., Hodgkinson, C., Hoffmann, P., Hottenga, J. J., Konte, B., Lahti, J., Lahti-Pulkkinen, M., Lai, D., Ligthart, L., Loukola, A., Maher, B. S., Mbarek, H., McIntosh, A. M., McQueen, M. B., Meyers, J. L., Milaneschi, Y., Palviainen, T., Peterson, R. E., Ryu, E., Saccone, N. L., Salvatore, J. E., Sanchez-Roige, S., Schwandt, M., Sherva, R., Streit, F., Strohmaier, J., Thomas, N., Wang, J. C., Webb, B. T., Wedow, R., Wetherill, L., Wills, A. G., Zhou, H., Boardman, J. D., Chen, D., Choi, D. S., Copeland, W. E., Culverhouse, R. C., Dahmen, N., Degenhardt, L., Domingue, B. W., Frye, M. A., Gäebel, W., Hayward, C., Ising, M., Keyes, M., Kiefer, F., Koller, G., Kramer, J., Kuperman, S., Lucae, S., Lynskey, M. T., Maier, W., Mann, K., Männistö, S., Müller-Myhsok, B., Murray, A. D., Nurnberger, J. I., Preuss, U., Räikkönen, K., Reynolds, M. D., Ridinger, M., Scherbaum, N., Schuckit, M. A., Soyka, M., Treutlein, J., Witt, S. H., Wodarz, N., Zill, P., Adkins, D. E., Boomsma, D. I., Bierut, L. J., Brown, S. A., Bucholz, K. K., Costello, E. J., de Wit, H., Diazgranados, N., Eriksson, J. G., Farrer, L. A., Foroud, T. M., Gillespie, N. A., Goate, A. M., Goldman, D., Grucza, R. A., Hancock, D. B., Harris, K. M., Hesselbrock, V., Hewitt, J. K., Hopfer, C. J., Iacono, W. G., Johnson, E. O., Karpyak, V. M., Kendler, K. S., Kranzler, H. R., Krauter, K., Lind, P. A., McGue, M., MacKillop, J., Madden, P. A. F., Maes, H. H., Magnusson, P. K. E., Nelson, E. C., Nöthen, M. M., Palmer, A. A., Penninx, B. W. J. H., Porjesz, B., Rice, J. P., Rietschel, M., Riley, B. P., Rose, R. J., Shen, P. H., Silberg, J., Stallings, M. C., Tarter, R. E., Vanyukov, M. M., Vrieze, S., Wall, T. L., Whitfield, J. B., Zhao, H., Neale, B. M., Wade, T. D., Heath, A. C., Montgomery, G. W., Martin, N. G., Sullivan, P. F., Kaprio, J., Breen, G., Gelernter, J., Edenberg, H. J., Bulik, C. M. & Agrawal, A., Jan 2021, In: Addiction Biology. 26, 1, e12880.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    28 Scopus citations
  • 2020

    A large-scale genome-wide association study meta-analysis of cannabis use disorder

    Psychiatric Genomics Consortium Substance Use Disorders Workgroup, Dec 1 2020, In: The Lancet Psychiatry. 7, 12, p. 1032-1045 14 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    127 Scopus citations
  • A phenome-wide association and Mendelian Randomisation study of polygenic risk for depression in UK Biobank

    Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium, Dec 1 2020, In: Nature communications. 11, 1, 2301.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    58 Scopus citations
  • Classical Human Leukocyte Antigen Alleles and C4 Haplotypes Are Not Significantly Associated With Depression

    Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium, Mar 1 2020, In: Biological Psychiatry. 87, 5, p. 419-430 12 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    19 Scopus citations
  • Genome-wide gene-environment analyses of major depressive disorder and reported lifetime traumatic experiences in UK Biobank

    Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium, Jul 1 2020, In: Molecular Psychiatry. 25, 7, p. 1430-1446 17 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    81 Scopus citations
  • Meta-analysis of up to 622,409 individuals identifies 40 novel smoking behaviour associated genetic loci

    Understanding Society Scientific Group, EPIC-CVD, GSCAN, Consortium for Genetics of Smoking Behaviour, CHD Exome+ consortium, Oct 1 2020, In: Molecular Psychiatry. 25, 10, p. 2392-2409 18 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    67 Scopus citations
  • Polygenic risk for anxiety influences anxiety comorbidity and suicidal behavior in bipolar disorder

    Bipolar Genome Study Consortium (BiGS), Dec 1 2020, In: Translational psychiatry. 10, 1, 298.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    16 Scopus citations
  • The Genetics of the Mood Disorder Spectrum: Genome-wide Association Analyses of More Than 185,000 Cases and 439,000 Controls

    Bipolar Disorder Working Group of the Psychiatric Genomics Consortium & Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium, Jul 15 2020, In: Biological Psychiatry. 88, 2, p. 169-184 16 p.

    Research output: Contribution to journalArticlepeer-review

    108 Scopus citations
  • 2019

    Assessment of bidirectional relationships between physical activity and depression among adults a 2-sample Mendelian randomization study

    Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium, Apr 2019, In: JAMA psychiatry. 76, 4, p. 399-408 10 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    334 Scopus citations
  • Association of Whole-Genome and NETRIN1 Signaling Pathway–Derived Polygenic Risk Scores for Major Depressive Disorder and White Matter Microstructure in the UK Biobank

    Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium & 23andMe Research Team, Jan 2019, In: Biological Psychiatry: Cognitive Neuroscience and Neuroimaging. 4, 1, p. 91-100 10 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    16 Scopus citations
  • Efficient region-based test strategy uncovers genetic risk factors for functional outcome in bipolar disorder

    Budde, M., Friedrichs, S., Alliey-Rodriguez, N., Ament, S., Badner, J. A., Berrettini, W. H., Bloss, C. S., Byerley, W., Cichon, S., Comes, A. L., Coryell, W., Craig, D. W., Degenhardt, F., Edenberg, H. J., Foroud, T., Forstner, A. J., Frank, J., Gershon, E. S., Goes, F. S., Greenwood, T. A., & 40 othersGuo, Y., Hipolito, M., Hood, L., Keating, B. J., Koller, D. L., Lawson, W. B., Liu, C., Mahon, P. B., McInnis, M. G., McMahon, F. J., Meier, S. M., Mühleisen, T. W., Murray, S. S., Nievergelt, C. M., Nurnberger, J. I., Nwulia, E. A., Potash, J. B., Quarless, D., Rice, J., Roach, J. C., Scheftner, W. A., Schork, N. J., Shekhtman, T., Shilling, P. D., Smith, E. N., Streit, F., Strohmaier, J., Szelinger, S., Treutlein, J., Witt, S. H., Zandi, P. P., Zhang, P., Zöllner, S., Bickeböller, H., Falkai, P. G., Kelsoe, J. R., Nöthen, M. M., Rietschel, M., Schulze, T. G. & Malzahn, D., Jan 2019, In: European Neuropsychopharmacology. 29, 1, p. 156-170 15 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    7 Scopus citations
  • Exome Chip Meta-analysis Fine Maps Causal Variants and Elucidates the Genetic Architecture of Rare Coding Variants in Smoking and Alcohol Use

    CHD Exome+ Consortium & Consortium for Genetics of Smoking Behaviour, Jun 1 2019, In: Biological Psychiatry. 85, 11, p. 946-955 10 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    47 Scopus citations
  • Genome-wide association study identifies 30 loci associated with bipolar disorder

    eQTLgen Consortium, BIOS Consortium & the Bipolar Disorder Working Group of the Psychiatric Genomics Consortium, May 1 2019, In: Nature Genetics. 51, 5, p. 793-803 11 p.

    Research output: Contribution to journalArticlepeer-review

    851 Scopus citations
  • Genome-wide Burden of Rare Short Deletions Is Enriched in Major Depressive Disorder in Four Cohorts

    Zhang, X., Abdellaoui, A., Rucker, J., de Jong, S., Potash, J. B., Weissman, M. M., Shi, J., Knowles, J. A., Pato, C., Pato, M., Sobell, J., Smit, J. H., Hottenga, J. J., de Geus, E. J. C., Lewis, C. M., Buttenschøn, H. N., Craddock, N., Jones, I., Jones, L., McGuffin, P., & 13 othersMors, O., Owen, M. J., Preisig, M., Rietschel, M., Rice, J. P., Rivera, M., Uher, R., Gejman, P. V., Sanders, A. R., Boomsma, D., Penninx, B. W. J. H., Breen, G. & Levinson, D. F., Jun 15 2019, In: Biological Psychiatry. 85, 12, p. 1065-1073 9 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    23 Scopus citations
  • Identification of common genetic risk variants for autism spectrum disorder

    Autism Spectrum Disorder Working Group of the Psychiatric Genomics Consortium, BUPGEN, Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium & 23andMe Research Team, Mar 1 2019, In: Nature Genetics. 51, 3, p. 431-444 14 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    1069 Scopus citations
  • Integrated analysis of environmental and genetic influences on cord blood DNA methylation in new-borns

    Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium, Dec 1 2019, In: Nature communications. 10, 1, 2548.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    78 Scopus citations
  • International meta-analysis of PTSD genome-wide association studies identifies sex- and ancestry-specific genetic risk loci

    Nievergelt, C. M., Maihofer, A. X., Klengel, T., Atkinson, E. G., Chen, C. Y., Choi, K. W., Coleman, J. R. I., Dalvie, S., Duncan, L. E., Gelernter, J., Levey, D. F., Logue, M. W., Polimanti, R., Provost, A. C., Ratanatharathorn, A., Stein, M. B., Torres, K., Aiello, A. E., Almli, L. M., Amstadter, A. B., & 159 othersAndersen, S. B., Andreassen, O. A., Arbisi, P. A., Ashley-Koch, A. E., Austin, S. B., Avdibegovic, E., Babić, D., Bækvad-Hansen, M., Baker, D. G., Beckham, J. C., Bierut, L. J., Bisson, J. I., Boks, M. P., Bolger, E. A., Børglum, A. D., Bradley, B., Brashear, M., Breen, G., Bryant, R. A., Bustamante, A. C., Bybjerg-Grauholm, J., Calabrese, J. R., Caldas- de- Almeida, J. M., Dale, A. M., Daly, M. J., Daskalakis, N. P., Deckert, J., Delahanty, D. L., Dennis, M. F., Disner, S. G., Domschke, K., Dzubur-Kulenovic, A., Erbes, C. R., Evans, A., Farrer, L. A., Feeny, N. C., Flory, J. D., Forbes, D., Franz, C. E., Galea, S., Garrett, M. E., Gelaye, B., Geuze, E., Gillespie, C., Uka, A. G., Gordon, S. D., Guffanti, G., Hammamieh, R., Harnal, S., Hauser, M. A., Heath, A. C., Hemmings, S. M. J., Hougaard, D. M., Jakovljevic, M., Jett, M., Johnson, E. O., Jones, I., Jovanovic, T., Qin, X. J., Junglen, A. G., Karstoft, K. I., Kaufman, M. L., Kessler, R. C., Khan, A., Kimbrel, N. A., King, A. P., Koen, N., Kranzler, H. R., Kremen, W. S., Lawford, B. R., Lebois, L. A. M., Lewis, C. E., Linnstaedt, S. D., Lori, A., Lugonja, B., Luykx, J. J., Lyons, M. J., Maples-Keller, J., Marmar, C., Martin, A. R., Martin, N. G., Maurer, D., Mavissakalian, M. R., McFarlane, A., McGlinchey, R. E., McLaughlin, K. A., McLean, S. A., McLeay, S., Mehta, D., Milberg, W. P., Miller, M. W., Morey, R. A., Morris, C. P., Mors, O., Mortensen, P. B., Neale, B. M., Nelson, E. C., Nordentoft, M., Norman, S. B., O’Donnell, M., Orcutt, H. K., Panizzon, M. S., Peters, E. S., Peterson, A. L., Peverill, M., Pietrzak, R. H., Polusny, M. A., Rice, J. P., Ripke, S., Risbrough, V. B., Roberts, A. L., Rothbaum, A. O., Rothbaum, B. O., Roy-Byrne, P., Ruggiero, K., Rung, A., Rutten, B. P. F., Saccone, N. L., Sanchez, S. E., Schijven, D., Seedat, S., Seligowski, A. V., Seng, J. S., Sheerin, C. M., Silove, D., Smith, A. K., Smoller, J. W., Sponheim, S. R., Stein, D. J., Stevens, J. S., Sumner, J. A., Teicher, M. H., Thompson, W. K., Trapido, E., Uddin, M., Ursano, R. J., van den Heuvel, L. L., Van Hooff, M., Vermetten, E., Vinkers, C. H., Voisey, J., Wang, Y., Wang, Z., Werge, T., Williams, M. A., Williamson, D. E., Winternitz, S., Wolf, C., Wolf, E. J., Wolff, J. D., Yehuda, R., Young, R. M. D., Young, K. A., Zhao, H., Zoellner, L. A., Liberzon, I., Ressler, K. J., Haas, M. & Koenen, K. C., Dec 1 2019, In: Nature communications. 10, 1, 4558.

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    262 Scopus citations
  • Polygenic risk for circulating reproductive hormone levels and their influence on hippocampal volume and depression susceptibility

    Smeeth, D. M., Dima, D., Jones, L., Jones, I., Craddock, N., Owen, M. J., Rietschel, M., Maier, W., Korszun, A., Rice, J. P., Mors, O., Preisig, M., Uher, R., Lewis, C. M., Thuret, S. & Powell, T. R., Aug 2019, In: Psychoneuroendocrinology. 106, p. 284-292 9 p.

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    15 Scopus citations
  • 2018

    A correction for sample overlap in genome-wide association studies in a polygenic pleiotropy-informed framework

    Schizophrenia and Bipolar Disorder Working Groups of the Psychiatric Genomics Consortium, Jun 25 2018, In: BMC genomics. 19, 1, 494.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    24 Scopus citations
  • Analysis of shared heritability in common disorders of the brain

    The Brainstorm Consortium, Jun 22 2018, In: Science. 360, 6395, 8757.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    1215 Scopus citations
  • Applying polygenic risk scoring for psychiatric disorders to a large family with bipolar disorder and major depressive disorder

    Major Depressive Disorder and Bipolar Disorder Working Groups of the Psychiatric Genomics Consortium, Dec 1 2018, In: Communications Biology. 1, 1, 163.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    14 Scopus citations
  • CYP2A6 metabolism in the development of smoking behaviors in young adults

    Olfson, E., Bloom, J., Bertelsen, S., Budde, J. P., Breslau, N., Brooks, A., Culverhouse, R., Chan, G., Chen, L. S., Chorlian, D., Dick, D. M., Edenberg, H. J., Hartz, S., Hatsukami, D., Hesselbrock, V. M., Johnson, E. O., Kramer, J. R., Kuperman, S., Meyers, J. L., Nurnberger, J., & 8 othersPorjesz, B., Saccone, N. L., Schuckit, M. A., Stitzel, J., Tischfield, J. A., Rice, J. P., Goate, A. & Bierut, L. J., Jan 2018, In: Addiction Biology. 23, 1, p. 437-447 11 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    7 Scopus citations
  • Detecting significant genotype–phenotype association rules in bipolar disorder: market research meets complex genetics

    Breuer, R., Mattheisen, M., Frank, J., Krumm, B., Treutlein, J., Kassem, L., Strohmaier, J., Herms, S., Mühleisen, T. W., Degenhardt, F., Cichon, S., Nöthen, M. M., Karypis, G., Kelsoe, J., Greenwood, T., Nievergelt, C., Shilling, P., Shekhtman, T., Edenberg, H., Craig, D., & 32 othersSzelinger, S., Nurnberger, J., Gershon, E., Alliey-Rodriguez, N., Zandi, P., Goes, F., Schork, N., Smith, E., Koller, D., Zhang, P., Badner, J., Berrettini, W., Bloss, C., Byerley, W., Coryell, W., Foroud, T., Guo, Y., Hipolito, M., Keating, B., Lawson, W., Liu, C., Mahon, P., McInnis, M., Murray, S., Nwulia, E., Potash, J., Rice, J., Scheftner, W., Zöllner, S., McMahon, F. J., Rietschel, M. & Schulze, T. G., Dec 1 2018, In: International Journal of Bipolar Disorders. 6, 1, 24.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    9 Scopus citations
  • Does Childhood Trauma Moderate Polygenic Risk for Depression? A Meta-analysis of 5765 Subjects From the Psychiatric Genomics Consortium

    Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium, Jul 15 2018, In: Biological Psychiatry. 84, 2, p. 138-147 10 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    69 Scopus citations
  • Exome sequencing of a large family identifies potential candidate genes contributing risk to bipolar disorder

    Zhang, T., Hou, L., Chen, D. T., McMahon, F. J., Wang, J. C. & Rice, J. P., Mar 1 2018, In: Gene. 645, p. 119-123 5 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    24 Scopus citations
  • Genome-wide association analyses identify 44 risk variants and refine the genetic architecture of major depression

    Wray, N. R., Ripke, S., Mattheisen, M., Trzaskowski, M., Byrne, E. M., Abdellaoui, A., Adams, M. J., Agerbo, E., Air, T. M., Andlauer, T. M. F., Bacanu, S. A., Bækvad-Hansen, M., Beekman, A. F. T., Bigdeli, T. B., Binder, E. B., Blackwood, D. R. H., Bryois, J., Buttenschøn, H. N., Bybjerg-Grauholm, J., Cai, N., & 196 othersCastelao, E., Christensen, J. H., Clarke, T. K., Coleman, J. I. R., Colodro-Conde, L., Couvy-Duchesne, B., Craddock, N., Crawford, G. E., Crowley, C. A., Dashti, H. S., Davies, G., Deary, I. J., Degenhardt, F., Derks, E. M., DIrek, N., Dolan, C. V., Dunn, E. C., Eley, T. C., Eriksson, N., Escott-Price, V., Kiadeh, F. H. F., Finucane, H. K., Forstner, A. J., Frank, J., Gaspar, H. A., Gill, M., Giusti-Rodríguez, P., Goes, F. S., Gordon, S. D., Grove, J., Hall, L. S., Hannon, E., Hansen, C. S., Hansen, T. F., Herms, S., Hickie, I. B., Hoffmann, P., Homuth, G., Horn, C., Hottenga, J. J., Hougaard, D. M., Hu, M., Hyde, C. L., Ising, M., Jansen, R., Jin, F., Jorgenson, E., Knowles, J. A., Kohane, I. S., Kraft, J., Kretzschmar, W. W., Krogh, J., Kutalik, Z., Lane, J. M., Li, Y., Li, Y., Lind, P. A., Liu, X., Lu, L., MacIntyre, D. J., MacKinnon, D. F., Maier, R. M., Maier, W., Marchini, J., Mbarek, H., McGrath, P., McGuffin, P., Medland, S. E., Mehta, DI., Middeldorp, C. M., Mihailov, E., Milaneschi, Y., Milani, L., Mill, J., Mondimore, F. M., Montgomery, G. W., Mostafavi, S., Mullins, N., Nauck, M., Ng, B., Nivard, M. G., Nyholt, D. R., O'Reilly, P. F., Oskarsson, H., Owen, M. J., Painter, J. N., Pedersen, C. B., Pedersen, M. G., Peterson, R. E., Pettersson, E., Peyrot, W. J., Pistis, G., Posthuma, D., Purcell, S. M., Quiroz, J. A., Qvist, P., Rice, J. P., Riley, B. P., Rivera, M., Saeed Mirza, S., Saxena, R., Schoevers, R., Schulte, E. C., Shen, L., Shi, J., Shyn, S. I., Sigurdsson, E., Sinnamon, G. B. C., Smit, J. H., Smith, D. J., Stefansson, H., Steinberg, S., Stockmeier, C. A., Streit, F., Strohmaier, J., Tansey, K. E., Teismann, H., Teumer, A., Thompson, W., Thomson, P. A., Thorgeirsson, T. E., Tian, C., Traylor, M., Treutlein, J., Trubetskoy, V., Uitterlinden, A. G., Umbricht, D., Van Der Auwera, S., Van Hemert, A. M., Viktorin, A., Visscher, P. M., Wang, Y., Webb, B. T., Weinsheimer, S. M., Wellmann, J., Willemsen, G., Witt, S. H., Wu, Y., Xi, H. S., Yang, J., Zhang, F., Arolt, V., Baune, B. T., Berger, K., Boomsma, D. I., Cichon, S., Dannlowski, U., De Geus, E. C. J., Depaulo, J. R., Domenici, E., Domschke, K., Esko, T., Grabe, H. J., Hamilton, S. P., Hayward, C., Heath, A. C., Hinds, D. A., Kendler, K. S., Kloiber, S., Lewis, G., Li, Q. S., Lucae, S., Madden, P. F. A., Magnusson, P. K., Martin, N. G., McIntosh, A. M., Metspalu, A., Mors, O., Mortensen, P. B., Müller-Myhsok, B., Nordentoft, M., Nöthen, M. M., O'Donovan, M. C., Paciga, S. A., Pedersen, N. L., Penninx, B. W. J. H., Perlis, R. H., Porteous, D. J., Potash, J. B., Preisig, M., Rietschel, M., Schaefer, C., Schulze, T. G., Smoller, J. W., Stefansson, K., Tiemeier, H., Uher, R., Völzke, H., Weissman, M. M., Werge, T., Winslow, A. R., Lewis, C. M., Levinson, D. F., Breen, G., Børglum, A. D. & Sullivan, P. F., May 1 2018, In: Nature Genetics. 50, 5, p. 668-681 14 p.

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    1583 Scopus citations
  • Genome-wide association study identifies a novel locus for cannabis dependence

    Agrawal, A., Chou, Y. L., Carey, C. E., Baranger, D. A. A., Zhang, B., Sherva, R., Wetherill, L., Kapoor, M., Wang, J. C., Bertelsen, S., Anokhin, A. P., Hesselbrock, V., Kramer, J., Lynskey, M. T., Meyers, J. L., Nurnberger, J. I., Rice, J. P., Tischfield, J., Bierut, L. J., Degenhardt, L., & 16 othersFarrer, L. A., Gelernter, J., Hariri, A. R., Heath, A. C., Kranzler, H. R., Madden, P. A. F., Martin, N. G., Montgomery, G. W., Porjesz, B., Wang, T., Whitfield, J. B., Edenberg, H. J., Foroud, T., Goate, A. M., Bogdan, R. & Nelson, E. C., May 1 2018, In: Molecular Psychiatry. 23, 5, p. 1293-1302 10 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    30 Scopus citations