John Rice

2018

Detecting significant genotype–phenotype association rules in bipolar disorder: market research meets complex genetics

Breuer, R., Mattheisen, M., Frank, J., Krumm, B., Treutlein, J., Kassem, L., Strohmaier, J., Herms, S., Mühleisen, T. W., Degenhardt, F., Cichon, S., Nöthen, M. M., Karypis, G., Kelsoe, J., Greenwood, T., Nievergelt, C., Shilling, P., Shekhtman, T., Edenberg, H. & Craig, D. & 32 others, Szelinger, S., Nurnberger, J., Gershon, E., Alliey-Rodriguez, N., Zandi, P., Goes, F., Schork, N., Smith, E., Koller, D., Zhang, P., Badner, J., Berrettini, W., Bloss, C., Byerley, W., Coryell, W., Foroud, T., Guo, Y., Hipolito, M., Keating, B., Lawson, W., Liu, C., Mahon, P., McInnis, M., Murray, S., Nwulia, E., Potash, J., Rice, J., Scheftner, W., Zöllner, S., McMahon, F. J., Rietschel, M. & Schulze, T. G., Dec 1 2018, In: International Journal of Bipolar Disorders. 6, 1, 24.

Research output: Contribution to journal › Article › peer-review

Open Access

12 Scopus citations

Does Childhood Trauma Moderate Polygenic Risk for Depression? A Meta-analysis of 5765 Subjects From the Psychiatric Genomics Consortium

Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium, Jul 15 2018, In: Biological Psychiatry. 84, 2, p. 138-147 10 p.

Research output: Contribution to journal › Article › peer-review

Open Access

77 Scopus citations

Exome sequencing of a large family identifies potential candidate genes contributing risk to bipolar disorder

Zhang, T., Hou, L., Chen, D. T., McMahon, F. J., Wang, J. C. & Rice, J. P., Mar 1 2018, In: Gene. 645, p. 119-123 5 p.

Research output: Contribution to journal › Article › peer-review

Open Access

27 Scopus citations

Genome-wide association analyses identify 44 risk variants and refine the genetic architecture of major depression

Wray, N. R., Ripke, S., Mattheisen, M., Trzaskowski, M., Byrne, E. M., Abdellaoui, A., Adams, M. J., Agerbo, E., Air, T. M., Andlauer, T. M. F., Bacanu, S. A., Bækvad-Hansen, M., Beekman, A. F. T., Bigdeli, T. B., Binder, E. B., Blackwood, D. R. H., Bryois, J., Buttenschøn, H. N., Bybjerg-Grauholm, J. & Cai, N. & 196 others, Castelao, E., Christensen, J. H., Clarke, T. K., Coleman, J. I. R., Colodro-Conde, L., Couvy-Duchesne, B., Craddock, N., Crawford, G. E., Crowley, C. A., Dashti, H. S., Davies, G., Deary, I. J., Degenhardt, F., Derks, E. M., DIrek, N., Dolan, C. V., Dunn, E. C., Eley, T. C., Eriksson, N., Escott-Price, V., Kiadeh, F. H. F., Finucane, H. K., Forstner, A. J., Frank, J., Gaspar, H. A., Gill, M., Giusti-Rodríguez, P., Goes, F. S., Gordon, S. D., Grove, J., Hall, L. S., Hannon, E., Hansen, C. S., Hansen, T. F., Herms, S., Hickie, I. B., Hoffmann, P., Homuth, G., Horn, C., Hottenga, J. J., Hougaard, D. M., Hu, M., Hyde, C. L., Ising, M., Jansen, R., Jin, F., Jorgenson, E., Knowles, J. A., Kohane, I. S., Kraft, J., Kretzschmar, W. W., Krogh, J., Kutalik, Z., Lane, J. M., Li, Y., Li, Y., Lind, P. A., Liu, X., Lu, L., MacIntyre, D. J., MacKinnon, D. F., Maier, R. M., Maier, W., Marchini, J., Mbarek, H., McGrath, P., McGuffin, P., Medland, S. E., Mehta, D., Middeldorp, C. M., Mihailov, E., Milaneschi, Y., Milani, L., Mill, J., Mondimore, F. M., Montgomery, G. W., Mostafavi, S., Mullins, N., Nauck, M., Ng, B., Nivard, M. G., Nyholt, D. R., O'Reilly, P. F., Oskarsson, H., Owen, M. J., Painter, J. N., Pedersen, C. B., Pedersen, M. G., Peterson, R. E., Pettersson, E., Peyrot, W. J., Pistis, G., Posthuma, D., Purcell, S. M., Quiroz, J. A., Qvist, P., Rice, J. P., Riley, B. P., Rivera, M., Saeed Mirza, S., Saxena, R., Schoevers, R., Schulte, E. C., Shen, L., Shi, J., Shyn, S. I., Sigurdsson, E., Sinnamon, G. B. C., Smit, J. H., Smith, D. J., Stefansson, H., Steinberg, S., Stockmeier, C. A., Streit, F., Strohmaier, J., Tansey, K. E., Teismann, H., Teumer, A., Thompson, W., Thomson, P. A., Thorgeirsson, T. E., Tian, C., Traylor, M., Treutlein, J., Trubetskoy, V., Uitterlinden, A. G., Umbricht, D., Van Der Auwera, S., Van Hemert, A. M., Viktorin, A., Visscher, P. M., Wang, Y., Webb, B. T., Weinsheimer, S. M., Wellmann, J., Willemsen, G., Witt, S. H., Wu, Y., Xi, H. S., Yang, J., Zhang, F., Arolt, V., Baune, B. T., Berger, K., Boomsma, D. I., Cichon, S., Dannlowski, U., De Geus, E. C. J., Depaulo, J. R., Domenici, E., Domschke, K., Esko, T., Grabe, H. J., Hamilton, S. P., Hayward, C., Heath, A. C., Hinds, D. A., Kendler, K. S., Kloiber, S., Lewis, G., Li, Q. S., Lucae, S., Madden, P. F. A., Magnusson, P. K., Martin, N. G., McIntosh, A. M., Metspalu, A., Mors, O., Mortensen, P. B., Müller-Myhsok, B., Nordentoft, M., Nöthen, M. M., O'Donovan, M. C., Paciga, S. A., Pedersen, N. L., Penninx, B. W. J. H., Perlis, R. H., Porteous, D. J., Potash, J. B., Preisig, M., Rietschel, M., Schaefer, C., Schulze, T. G., Smoller, J. W., Stefansson, K., Tiemeier, H., Uher, R., Völzke, H., Weissman, M. M., Werge, T., Winslow, A. R., Lewis, C. M., Levinson, D. F., Breen, G., Børglum, A. D. & Sullivan, P. F., May 1 2018, In: Nature Genetics. 50, 5, p. 668-681 14 p.

Research output: Contribution to journal › Article › peer-review

Open Access

1771 Scopus citations

Genome-wide association study identifies a novel locus for cannabis dependence

Agrawal, A., Chou, Y. L., Carey, C. E., Baranger, D. A. A., Zhang, B., Sherva, R., Wetherill, L., Kapoor, M., Wang, J. C., Bertelsen, S., Anokhin, A. P., Hesselbrock, V., Kramer, J., Lynskey, M. T., Meyers, J. L., Nurnberger, J. I., Rice, J. P., Tischfield, J., Bierut, L. J. & Degenhardt, L. & 16 others, Farrer, L. A., Gelernter, J., Hariri, A. R., Heath, A. C., Kranzler, H. R., Madden, P. A. F., Martin, N. G., Montgomery, G. W., Porjesz, B., Wang, T., Whitfield, J. B., Edenberg, H. J., Foroud, T., Goate, A. M., Bogdan, R. & Nelson, E. C., May 1 2018, In: Molecular Psychiatry. 23, 5, p. 1293-1302 10 p.

Research output: Contribution to journal › Article › peer-review

Open Access

31 Scopus citations

Genome-wide interaction study of a proxy for stress-sensitivity and its prediction of major depressive disorder

Generation Scotland & Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium, Dec 2018, In: PloS one. 13, 12, e0209160.

Research output: Contribution to journal › Article › peer-review

Open Access

13 Scopus citations

Genomic Dissection of Bipolar Disorder and Schizophrenia, Including 28 Subphenotypes

Bipolar Disorder and Schizophrenia Working Group of the Psychiatric Genomics Consortium [email protected], Psychosis Endophenotypes International Consortium & Wellcome Trust Case Control Consortium, Jun 14 2018, In: Cell. 173, 7, p. 1705-1715.e16

Research output: Contribution to journal › Article › peer-review

Open Access

440 Scopus citations

Improving genetic prediction by leveraging genetic correlations among human diseases and traits

Maier, R. M., Zhu, Z., Lee, S. H., Trzaskowski, M., Ruderfer, D. M., Stahl, E. A., Ripke, S., Wray, N. R., Yang, J., Visscher, P. M., Robinson, M. R., Forstner, A. J., Mcquillin, A., Trubetskoy, V., Wang, W., Wang, Y., Coleman, J. R. I., Gaspar, H. A., De Leeuw, C. A. & Whitehead Pavlides, J. M. & 221 others, Olde Loohuis, L. M., Pers, T. H., Lee, P. H., Charney, A. W., Dobbyn, A. L., Huckins, L., Boocock, J., Giambartolomei, C., Roussos, P., Mullins, N., Awasthi, S., Agerbo, E., Als, T. D., Pedersen, C. B., Grove, J., Kupka, R., Regeer, E. J., Anjorin, A., Casas, M., Mahon, P. B., Allardyce, J., Escott-Price, V., Forty, L., Fraser, C., Kogevinas, M., Frank, J., Streit, F., Strohmaier, J., Treutlein, J., Witt, S. H., Kennedy, J. L., Strauss, J. S., Garnham, J., O'donovan, C., Slaney, C., Steinberg, S., Thorgeirsson, T. E., Hautzinger, M., Steffens, M., Perlis, R. H., Sánchez-Mora, C., Hipolito, M., Lawson, W. B., Nwulia, E. A., Levy, S. E., Foroud, T. M., Jamain, S., Young, A. H., Mckay, J. D., Albani, D., Zandi, P., Potash, J. B., Zhang, P., Raymond Depaulo, J., Bergen, S. E., Juréus, A., Karlsson, R., Kandaswamy, R., Mcguffin, P., Rivera, M., Lissowska, J., Cruceanu, C., Lucae, S., Cervantes, P., Budde, M., Gade, K., Heilbronner, U., Pedersen, M. G., Morris, D. W., Weickert, C. S., Weickert, T. W., Macintyre, D. J., Lawrence, J., Elvsåshagen, T., Smeland, O. B., Djurovic, S., Xi, S., Green, E. K., Czerski, P. M., Hauser, J., Xu, W., Vedder, H., Oruc, L., Spijker, A. T., Gordon, S. D., Medland, S. E., Curtis, D., Mühleisen, T. W., Badner, J., Scheftner, W. A., Sigurdsson, E., Schork, N. J., Schatzberg, A. F., Bækvad-Hansen, M., Bybjerg-Grauholm, J., Hansen, C. S., Knowles, J. A., Szelinger, S., Montgomery, G. W., Boks, M., Adolfsson, A. N., Hoffmann, P., Bauer, M., Pfennig, A., Leber, M., Kittel-Schneider, S., Reif, A., Del-Favero, J., Fischer, S. B., Herms, S., Reinbold, C. S., Degenhardt, F., Koller, A. C., Maaser, A., Ori, A., Dale, A. M., Fan, C. C., Greenwood, T. A., Nievergelt, C. M., Shehktman, T., Shilling, P. D., Byerley, W., Bunney, W., Alliey-Rodriguez, N., Clarke, T. K., Liu, C., Coryell, W., Akil, H., Burmeister, M., Flickinger, M., Li, J. Z., Mcinnis, M. G., Meng, F., Thompson, R. C., Watson, S. J., Zollner, S., Guan, W., Green, M. J., Craig, D., Sobell, J. L., Milani, L., Gordon-Smith, K., Knott, S. V., Perry, A., Parra, J. G., Mayoral, F., Rivas, F., Rice, J. P., Barchas, J. D., Børglum, A. D., Mortensen, P. B., Mors, O., Grigoroiu-Serbanescu, M., Bellivier, F., Etain, B., Leboyer, M., Ramos-Quiroga, J. A., Agartz, I., Amin, F., Azevedo, M. H., Bass, N., Black, D. W., Blackwood, D. H. R., Bruggeman, R., Buccola, N. G., Choudhury, K., Cloninger, C. R., Corvin, A., Craddock, N., Daly, M. J., Datta, S., Donohoe, G. J., Duan, J., Dudbridge, F., Fanous, A., Freedman, R., Freimer, N. B., Friedl, M., Gill, M., Gurling, H., De Haan, L., Hamshere, M. L., Hartmann, A. M., Holmans, P. A., Kahn, R. S., Keller, M. C., Kenny, E., Kirov, G. K., Krabbendam, L., Krasucki, R., Lencz, T., Levinson, D. F., Lieberman, J. A., Lin, D. Y., Linszen, D. H., Magnusson, P. K. E., Maier, W., Malhotra, A. K., Mattheisen, M., Mattingsdal, M., Mccarroll, S. A., Medeiros, H., Melle, I., Milanova, V., Myin-Germeys, I., Neale, B. M., Ophoff, R. A., Owen, M. J., Pimm, J., Purcell, S. M., Puri, V., Quested, D. J., Rossin, L., Sanders, A. R., Shi, J., Sklar, P., St Clair, D., Stroup, T. S., Van Os, J., Wiersma, D. & Zammit, S., Dec 1 2018, In: Nature communications. 9, 1, 989.

Research output: Contribution to journal › Editorial

Open Access

103 Scopus citations

Largest GWAS of PTSD (N=20 070) yields genetic overlap with schizophrenia and sex differences in heritability

Duncan, L. E., Ratanatharathorn, A., Aiello, A. E., Almli, L. M., Amstadter, A. B., Ashley-Koch, A. E., Baker, D. G., Beckham, J. C., Bierut, L. J., Bisson, J., Bradley, B., Chen, C. Y., Dalvie, S., Farrer, L. A., Galea, S., Garrett, M. E., Gelernter, J. E., Guffanti, G., Hauser, M. A. & Johnson, E. O. & 29 others, Kessler, R. C., Kimbrel, N. A., King, A., Koen, N., Kranzler, H. R., Logue, M. W., Maihofer, A. X., Martin, A. R., Miller, M. W., Morey, R. A., Nugent, N. R., Rice, J. P., Ripke, S., Roberts, A. L., Saccone, N. L., Smoller, J. W., Stein, D. J., Stein, M. B., Sumner, J. A., Uddin, M., Ursano, R. J., Wildman, D. E., Yehuda, R., Zhao, H., Daly, M. J., Liberzon, I., Ressler, K. J., Nievergelt, C. M. & Koenen, K. C., Mar 1 2018, In: Molecular Psychiatry. 23, 3, p. 666-673 8 p.

Research output: Contribution to journal › Article › peer-review

Open Access

290 Scopus citations

Transancestral GWAS of alcohol dependence reveals common genetic underpinnings with psychiatric disorders

23andMe Research Team, Dec 1 2018, In: Nature neuroscience. 21, 12, p. 1656-1669 14 p.

Research output: Contribution to journal › Article › peer-review

Open Access

378 Scopus citations

Voltage-gated calcium channel activity and complex related genes and schizophrenia: A systematic investigation based on Han Chinese population

Zhang, T., Zhu, L., Ni, T., Liu, D., Chen, G., Yan, Z., Lin, H., Guan, F. & Rice, J. P., Nov 2018, In: Journal of Psychiatric Research. 106, p. 99-105 7 p.

Research output: Contribution to journal › Article › peer-review

46 Scopus citations

2017

An Analysis of Two Genome-wide Association Meta-analyses Identifies a New Locus for Broad Depression Phenotype

Direk, N., Williams, S., Smith, J. A., Ripke, S., Air, T., Amare, A. T., Amin, N., Baune, B. T., Bennett, D. A., Blackwood, D. H. R., Boomsma, D., Breen, G., Buttenschøn, H. N., Byrne, E. M., Børglum, A. D., Castelao, E., Cichon, S., Clarke, T. K., Cornelis, M. C. & Dannlowski, U. & 82 others, De Jager, P. L., Demirkan, A., Domenici, E., van Duijn, C. M., Dunn, E. C., Eriksson, J. G., Esko, T., Faul, J. D., Ferrucci, L., Fornage, M., de Geus, E., Gill, M., Gordon, S. D., Grabe, H. J., van Grootheest, G., Hamilton, S. P., Hartman, C. A., Heath, A. C., Hek, K., Hofman, A., Homuth, G., Horn, C., Jan Hottenga, J., Kardia, S. L. R., Kloiber, S., Koenen, K., Kutalik, Z., Ladwig, K. H., Lahti, J., Levinson, D. F., Lewis, C. M., Lewis, G., Li, Q. S., Llewellyn, D. J., Lucae, S., Lunetta, K. L., MacIntyre, D. J., Madden, P., Martin, N. G., McIntosh, A. M., Metspalu, A., Milaneschi, Y., Montgomery, G. W., Mors, O., Mosley, T. H., Murabito, J. M., Müller-Myhsok, B., Nöthen, M. M., Nyholt, D. R., O'Donovan, M. C., Penninx, B. W., Pergadia, M. L., Perlis, R., Potash, J. B., Preisig, M., Purcell, S. M., Quiroz, J. A., Räikkönen, K., Rice, J. P., Rietschel, M., Rivera, M., Schulze, T. G., Shi, J., Shyn, S., Sinnamon, G. C., Smit, J. H., Smoller, J. W., Snieder, H., Tanaka, T., Tansey, K. E., Teumer, A., Uher, R., Umbricht, D., Van der Auwera, S., Ware, E. B., Weir, D. R., Weissman, M. M., Willemsen, G., Yang, J., Zhao, W., Tiemeier, H. & Sullivan, P. F., Sep 1 2017, In: Biological Psychiatry. 82, 5, p. 322-329 8 p.

Research output: Contribution to journal › Article › peer-review

Open Access

58 Scopus citations

A putative causal relationship between genetically determined female body shape and posttraumatic stress disorder

for The Psychiatric Genomics Consortium Posttraumatic Stress Disorder Workgroup, Nov 27 2017, In: Genome medicine. 9, 1, 99.

Research output: Contribution to journal › Article › peer-review

Open Access

22 Scopus citations

Association Between Substance Use Disorder and Polygenic Liability to Schizophrenia

Hartz, S. M., Horton, A. C., Oehlert, M., Carey, C. E., Agrawal, A., Bogdan, R., Chen, L. S., Hancock, D. B., Johnson, E. O., Pato, C. N., Pato, M. T., Rice, J. P. & Bierut, L. J., Nov 15 2017, In: Biological Psychiatry. 82, 10, p. 709-715 7 p.

Research output: Contribution to journal › Article › peer-review

Open Access

52 Scopus citations

Evidence for three genetic loci involved in both anorexia nervosa risk and variation of body mass index

Children's Hospital of Philadelphia/Price Foundation, GCAN, WTCCC3, GIANT, EGG & Price Foundation Collaborative Group, Feb 1 2017, In: Molecular Psychiatry. 22, 2, p. 192-201 10 p.

Research output: Contribution to journal › Article › peer-review

Open Access

50 Scopus citations

Genetic association of major depression with a typical features and obesity-related immunometabolic dysregulations

CHARGE InflammationWorking Group and the Major Depressive DisorderWorking Group of the Psychiatric Genomics Consortium, Dec 2017, In: JAMA psychiatry. 74, 12, p. 1214-1225 12 p.

Research output: Contribution to journal › Article › peer-review

Open Access

151 Scopus citations

Genetic effects influencing risk for major depressive disorder in China and Europe

on behalf of the CONVERGE consortium and Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium, 2017, In: Translational psychiatry. 7, 3, e1074.

Research output: Contribution to journal › Article › peer-review

Open Access

53 Scopus citations

Genetic Overlap Between Attention-Deficit/Hyperactivity Disorder and Bipolar Disorder: Evidence From Genome-wide Association Study Meta-analysis

PGC ADHD Working Group, PGC Bipolar Disorder Working Group, van Hulzen, K. J. E., Scholz, C. J., Franke, B., Ripke, S., Klein, M., McQuillin, A., Sonuga-Barke, E. J. S., Kelsoe, J. R., Landén, M., Andreassen, O. A., Lesch, K. P., Weber, H., Faraone, S. V., Arias-Vasquez, A., Reif, A., Anney, R. J. L., Vasquez, A. A. & Arranz, M. J. & 182 others, Asherson, P., Banaschewski, T. J., Bayés, M., Biederman, J., Buitelaar, J. K., Casas, M., Charach, A., Cormand, B., Crosbie, J., Dalsgaard, S., Daly, M. J., Doyle, A. E., Ebstein, R. P., Elia, J., Freitag, C., Gill, M., Hakonarson, H., Hervas, A., Holmans, P., Kent, L., Kuntsi, J., Lambregts-Rommelse, N., Langley, K., Loo, S. K., Martin, J., McGough, J. J., Medland, S. E., Meyer, J., Mick, E., Miranda, A., Mulas, F., Neale, B. M., Nelson, S. F., O’Donovan, M. C., Oades, R. D., Owen, M. J., Palmason, H., Ramos-Quiroga, J. A., Ribasés, M., Roeyers, H., Romanos, J., Romanos, M., Rothenberger, A., Sánchez-Mora, C., Schachar, R., Sergeant, J., Smalley, S. L., Steinhausen, H. C., Thapar, A., Todorov, A., Walitza, S., Wang, Y., Warnke, A., Williams, N., Zhang-James, Y., Absher, D., Akil, H., Anjorin, A., Backlund, L., Badner, J. A., Barchas, J. D., Barrett, T. B., Bass, N., Bauer, M., Bellivier, F., Bergen, S. E., Berrettini, W., Blackwood, D., Bloss, C. S., Boehnke, M., Breen, G., Breuer, R., Bunney, W. E., Burmeister, M., Byerley, W., Caesar, S., Chambert, K., Cichon, S., Collier, D. A., Corvin, A., Coryell, W., Craddock, N., Craig, D. W., Daly, M., Day, R., Degenhardt, F., Djurovic, S., Dudbridge, F., Edenberg, H. J., Elkin, A., Etain, B., Farmer, A., Ferreira, M., Ferrier, I. N., Flickinger, M., Foroud, T., Frank, J., Fraser, C., Frisén, L., Fullerton, J., Gershon, E. S., Gordon-Smith, K., Green, E. K., Greenwood, T. A., Grozeva, D., Guan, W., Gurling, H., Gustafsson, Ó., Hamshere, M. L., Hautzinger, M., Henry, C., Herms, S., Hipolito, M. M., Hultman, C., Jamain, S., Jones, E. G., Jones, I. R., Jones, L., Kahn, J. P., Kandaswamy, R., Kennedy, J. L., Kirov, G., Koller, D. L., Kwan, P., Langstrom, N., Lathrop, M., Lawrence, J., Lawson, W. B., Leboyer, M., Lee, P. H., Li, J., Lichtenstein, P., Lin, D., Liu, C., Lohoff, F. W., Lucae, S., Mahon, P. B., Maier, S., Maier, W., Martin, N., Mattheisen, M., Matthews, K., Mattingsdal, M., McGhee, K., McGuffin, P., McInnis, M. G., McIntosh, A., McKinney, R., McLean, A. W., McMahon, F. J., Melle, I., Guo Meng, F., Mitchell, P. B., Montgomery, G. W., Moran, J., Morken, G., Morris, D., Moskvina, V., Muglia, P., Mühleisen, T. W., Muir, W. J., Müller-Mysok, B., Myers, R. M., Nievergelt, C. M., Nikolov, I., Nimgaonkar, V., Nöthen, M. M., Nurnberger, J. I., Nwulia, E. A., O'Dushlaine, C., Osby, U., Óskarsson, H., Perlis, R., Petursson, H., Pickard, B. S., Potash, J. B., Propping, P., Purcell, S., Quinn, E., Raychaudhuri, S., Rice, J. & Rietschel, M., Nov 1 2017, In: Biological Psychiatry. 82, 9, p. 634-641 8 p.

Research output: Contribution to journal › Article › peer-review

Open Access

93 Scopus citations

Genomewide Association Study of Alcohol Dependence Identifies Risk Loci Altering Ethanol-Response Behaviors in Model Organisms

Collaborative Study of the Genetics of Alcoholism Consortium & the German Study of the Genetics of Addiction Consortium, May 2017, In: Alcoholism: Clinical and Experimental Research. 41, 5, p. 911-928 18 p.

Research output: Contribution to journal › Article › peer-review

Open Access

38 Scopus citations

Hair Cortisol in Twins: Heritability and Genetic Overlap with Psychological Variables and Stress-System Genes

Rietschel, L., Streit, F., Zhu, G., McAloney, K., Frank, J., Couvy-Duchesne, B., Witt, S. H., Binz, T. M., Bolton, J. L., Hayward, C., Direk, N., Anderson, A., Huffman, J., Wilson, J. F., Campbell, H., Rudan, I., Wright, A., Hastie, N., Wild, S. H. & Velders, F. P. & 215 others, Hofman, A., Uitterlinden, A. G., Lahti, J., Räikkönen, K., Kajantie, E., Widen, E., Palotie, A., Eriksson, J. G., Kaakinen, M., Järvelin, M. R., Timpson, N. J., Davey Smith, G., Ring, S. M., Evans, D. M., St Pourcain, B., Tanaka, T., Milaneschi, Y., Bandinelli, S., Ferrucci, L., Van Der Harst, P., Rosmalen, J. G., Bakker, S. J., Verweij, N., Dullaart, R. P., Mahajan, A., Lindgren, C. M., Morris, A., Lind, L., Ingelsson, E., Anderson, L. N., Pennell, C. E., Lye, S. J., Matthews, S. G., Eriksson, J., Mellstrom, D., Ohlsson, C., Price, J. F., Strachan, M. W., Reynolds, R. M., Tiemeier, H., Ripke, S., Mattheisen, M., Abdellaoui, A., Adams, M. J., Agerbo, E., Air, T. M., Andlauer, T. F., Bacanu, S. A., Bækvad-Hansen, M., Beekman, A. T., Bennett, D. A., Berger, K., Bigdeli, T. B., Bybjerg-Grauholm, J., Byrne, E. M., Cai, N., Castelao, E., Clarke, T. K., Coleman, J. R., Consortium, C., Craddock, N., Dannlowski, U., Davies, G., Davies, G., De Geus, E. J. C., De Jager, P., Deary, I. J., Degenhardt, F., Dunn, E. C., Ehli, E. A., Eley, T. C., Escott-Price, V., Esko, T., Finucane, H. K., Gill, M., Gordon, S. D., Grove, J., Hall, L. S., Hansen, T. F., Søholm Hansen, C., Heath, A. C., Henders, A. K., Herms, S., Hoffmann, P., Homuth, G., Horn, C., Hottenga, J. J., Hougaard, D., Huang, H., Ising, M., Jansen, R., Jorgenson, E., Kloiber, S., Knowles, J. A., Kretzschmar, W. W., Krogh, J., Kutalik, Z., Lang, M., Lewis, G., Li, Y., MacIntyre, D. J., Madden, P. A., Marchine, J., Mbarek, H., McGuffin, P., Mehta, D., Metspalu, A., Middeldorp, C. M., Mihailov, E., Milani, L., Montgomery, G. W., Mostafavi, S., Mullins, N., Nauck, M., Ng, B., Nordentoft, M., Nyholt, D. R., O'Donovan, M. C., O'Reilly, P. F., Oskarsson, H., Owen, M. J., Paciga, S. A., Pedersen, C. B., Pedersen, M. G., Pedersen, N. L., Pergadia, M. L., Peterson, R. E., Pettersson, E., Peyrot, W. J., Porteous, D. J., Posthuma, D., Potash, J. B., Quiroz, J. A., Rice, J. P., Riley, B. P., Rivera, M., Ruderfer, D. M., Saeed Mirza, S., Schoevers, R., Shen, L., Shi, J., Sigurdsson, E., Sinnamon, G. C., Smit, J. H., Smith, D. J., Stephansson, H., Steinberg, S., Strohmaier, J., Tansey, K. E., Teumer, A., Thompson, W., Thomson, P. A., Thorgeirsson, T. E., Treutlein, J., Trzaskowski, M., Umbricht, D., Van Der Auwera, S., Van Grootheest, G., Van Hemert, A. M., Viktorin, A., Völzke, H., Wang, Y., Webb, B. T., Weissman, M. M., Wellmann, J., Willemsen, G., Xi, H. S., Baune, B. T., Blackwood, D. H. R., Boomsma, D. I., Børglum, A. D., Buttenschøn, H. N., Cichon, S., Domenici, E., Flint, J., Grabe, H. J., Hamilton, S. P., Kendler, K. S., Li, Q. S., Lucae, S., Magnusson, P. K., McIntosh, A. M., Mors, O., Bo Mortensen, P., Müller-Myhsok, B., Penninx, B. W., Perlis, R. H., Preisig, M., Schaefer, C., Smoller, J. W., Stephansson, K., Uher, R., Werge, T., Winslow, A. R., Breen, G., Levinson, D. F., Lewis, C. M., Wray, N. R., Sullivan, P. F., McGrath, J., Hickie, I. B., Hansell, N. K., Wright, M. J., Gillespie, N. A., Forstner, A. J., Schulze, T. G., Wüst, S., Nöthen, M. M., Baumgartner, M. R., Walker, B. R., Crawford, A. A., Colodro-Conde, L., Medland, S. E., Martin, N. G. & Rietschel, M., Dec 1 2017, In: Scientific reports. 7, 1, 15351.

Research output: Contribution to journal › Article › peer-review

Open Access

53 Scopus citations

Interaction between the FTO gene, body mass index and depression: Meta-analysis of 13701 individuals

Rivera, M., Locke, A., Corre, T., Czamara, D., Wolf, C., Ching-Lopez, A., Milaneschi, Y., Kloiber, S., Cohen-Woods, S., Rucker, J., Aitchison, K. J., Bergmann, S., Boomsma, D. I., Craddock, N., Gill, M., Holsboer, F., Hottenga, J. J., Korszun, A., Kutalik, Z. & Lucae, S. & 18 others, Maier, W., Mors, O., Muller-Myhsok, B., Owen, M. J., Penninx, B. W. J. H., Preisig, M., Rice, J., Rietschel, M., Tozzi, F., Uher, R., Vollenweider, P., Waeber, G., Willemsen, G., Craig, I. W., Farmer, A. E., Lewis, C. M., Breen, G. & McGuffin, P., Aug 2017, In: British Journal of Psychiatry. 211, 2, p. 70-76 7 p.

Research output: Contribution to journal › Review article › peer-review

Open Access

47 Scopus citations

Polygenic Scores for Major Depressive Disorder and Risk of Alcohol Dependence

Andersen, A. M., Pietrzak, R. H., Kranzler, H. R., Ma, L., Zhou, H., Liu, X., Kramer, J., Kuperman, S., Edenberg, H. J., Nurnberger, J. I., Rice, J. P., Tischfield, J. A., Goate, A., Foroud, T. M., Meyers, J. L., Porjesz, B., Dick, D. M., Hesselbrock, V., Boerwinkle, E. & Southwick, S. M. & 6 others, Krystal, J. H., Weissman, M. M., Levinson, D. F., Potash, J. B., Gelernter, J. & Han, S., Nov 1 2017, In: JAMA psychiatry. 74, 11, p. 1153-1160 8 p.

Research output: Contribution to journal › Article › peer-review

Open Access

70 Scopus citations

Targeted sequencing identifies genetic polymorphisms of flavin-containing monooxygenase genes contributing to susceptibility of nicotine dependence in European American and African American

Zhang, T. X., Saccone, N. L., Bierut, L. J. & Rice, J. P., Apr 2017, In: Brain and Behavior. 7, 4, e00651.

Research output: Contribution to journal › Article › peer-review

Open Access

12 Scopus citations

The Impact of Peer Substance Use and Polygenic Risk on Trajectories of Heavy Episodic Drinking Across Adolescence and Emerging Adulthood

COGA Investigators, Jan 1 2017, In: Alcoholism: Clinical and Experimental Research. 41, 1, p. 65-75 11 p.

Research output: Contribution to journal › Article › peer-review

Open Access

29 Scopus citations

Variation in SWI/SNF Chromatin Remodeling Complex Proteins is Associated with Alcohol Dependence and Antisocial Behavior in Human Populations

COGA Investigators, Dec 2017, In: Alcoholism: Clinical and Experimental Research. 41, 12, p. 2033-2040 8 p.

Research output: Contribution to journal › Article › peer-review

Open Access

11 Scopus citations

2016

A genome-wide association study of bipolar disorder with comorbid eating disorder replicates the SOX2-OT region

Bipolar Genome Study (BiGS), Jan 1 2016, In: Journal of affective disorders. 189, p. 141-149 9 p., 7712.

Research output: Contribution to journal › Article › peer-review

Open Access

44 Scopus citations

Evidence of CNIH3 involvement in opioid dependence

Nelson, E. C., Agrawal, A., Heath, A. C., Bogdan, R., Sherva, R., Zhang, B., Al-Hasani, R., Bruchas, M. R., Chou, Y. L., Demers, C. H., Carey, C. E., Conley, E. D., Fakira, A. K., Farrer, L. A., Goate, A., Gordon, S., Henders, A. K., Hesselbrock, V., Kapoor, M. & Lynskey, M. T. & 19 others, Madden, P. A. F., Moron, J. A., Rice, J. P., Saccone, N. L., Schwab, S. G., Shand, F. L., Todorov, A. A., Wallace, L., Wang, T., Wray, N. R., Zhou, X., Degenhardt, L., Martin, N. G., Hariri, A. R., Kranzler, H. R., Gelernter, J., Bierut, L. J., Clark, D. J. & Montgomery, G. W., May 1 2016, In: Molecular Psychiatry. 21, 5, p. 608-614 7 p.

Research output: Contribution to journal › Article › peer-review

Open Access

90 Scopus citations

Genome-wide association study of 40,000 individuals identifies two novel loci associated with bipolar disorder

Hou, L., Bergen, S. E., Akula, N., Song, J., Hultman, C. M., Landén, M., Adli, M., Alda, M., Ardau, R., Arias, B., Aubry, J. M., Backlund, L., Badner, J. A., Barrett, T. B., Bauer, M., Baune, B. T., Bellivier, F., Benabarre, A., Bengesser, S. & Berrettini, W. H. & 119 others, Bhattacharjee, A. K., Biernacka, J. M., Birner, A., Bloss, C. S., Brichant-Petitjean, C., Bui, E. T., Byerley, W., Cervantes, P., Chillotti, C., Cichon, S., Colom, F., Coryell, W., Craig, D. W., Cruceanu, C., Czerski, P. M., Davis, T., Dayer, A., Degenhardt, F., Del Zompo, M., DePaulo, J. R., Edenberg, H. J., Étain, B., Falkai, P., Foroud, T., Forstner, A. J., Frisén, L., Frye, M. A., Fullerton, J. M., Gard, S., Garnham, J. S., Gershon, E. S., Goes, F. S., Greenwood, T. A., Grigoroiu-Serbanescu, M., Hauser, J., Heilbronner, U., Heilmann-Heimbach, S., Herms, S., Hipolito, M., Hitturlingappa, S., Hoffmann, P., Hofmann, A., Jamain, S., Jiménez, E., Kahn, J. P., Kassem, L., Kelsoe, J. R., Kittel-Schneider, S., Kliwicki, S., Koller, D. L., König, B., Lackner, N., Laje, G., Lang, M., Lavebratt, C., Lawson, W. B., Leboyer, M., Leckband, S. G., Liu, C., Maaser, A., Mahon, P. B., Maier, W., Maj, M., Manchia, M., Martinsson, L., McCarthy, M. J., McElroy, S. L., McInnis, M. G., McKinney, R., Mitchell, P. B., Mitjans, M., Mondimore, F. M., Monteleone, P., Mühleisen, T. W., Nievergelt, C. M., Nöthen, M. M., Novák, T., Nurnberger, J. I., Nwulia, E. A., Ösby, U., Pfennig, A., Potash, J. B., Propping, P., Reif, A., Reininghaus, E., Rice, J., Rietschel, M., Rouleau, G. A., Rybakowski, J. K., Schalling, M., Scheftner, W. A., Schofield, P. R., Schork, N. J., Schulze, T. G., Schumacher, J., Schweizer, B. W., Severino, G., Shekhtman, T., Shilling, P. D., Simhandl, C., Slaney, C. M., Smith, E. N., Squassina, A., Stamm, T., Stopkova, P., Streit, F., Strohmaier, J., Szelinger, S., Tighe, S. K., Tortorella, A., Turecki, G., Vieta, E., Volkert, J., Witt, S. H., Wright, A., Zandi, P. P., Zhang, P., Zollner, S. & McMahon, F. J., Aug 1 2016, In: Human molecular genetics. 25, 15, p. 3383-3394 12 p.

Research output: Contribution to journal › Article › peer-review

Open Access

133 Scopus citations

Phenotypic association analyses with copy number variation in recurrent depressive disorder

Rucker, J. J. H., Tansey, K. E., Rivera, M., Pinto, D., Cohen-Woods, S., Uher, R., Aitchison, K. J., Craddock, N., Owen, M. J., Jones, L., Jones, I., Korszun, A., Barnes, M. R., Preisig, M., Mors, O., Maier, W., Rice, J., Rietschel, M., Holsboer, F. & Farmer, A. E. & 4 others, Craig, I. W., Scherer, S. W., McGuffin, P. & Breen, G., Feb 15 2016, In: Biological Psychiatry. 79, 4, p. 329-336 8 p.

Research output: Contribution to journal › Article › peer-review

Open Access

18 Scopus citations

Rare, low frequency and common coding variants in CHRNA5 and their contribution to nicotine dependence in European and African Americans

Olfson, E., Saccone, N. L., Johnson, E. O., Chen, L. S., Culverhouse, R., Doheny, K., Foltz, S. M., Fox, L., Gogarten, S. M., Hartz, S., Hetrick, K., Laurie, C. C., Marosy, B., Amin, N., Arnett, D., Barr, R. G., Bartz, T. M., Bertelsen, S., Borecki, I. B. & Brown, M. R. & 33 others, Chasman, D. I., Van Duijn, C. M., Feitosa, M. F., Fox, E. R., Franceschini, N., Franco, O. H., Grove, M. L., Guo, X., Hofman, A., Kardia, S. L. R., Morrison, A. C., Musani, S. K., Psaty, B. M., Rao, D. C., Reiner, A. P., Rice, K., Ridker, P. M., Rose, L. M., Schick, U. M., Schwander, K., Uitterlinden, A. G., Vojinovic, D., Wang, J. C., Ware, E. B., Wilson, G., Yao, J., Zhao, W., Breslau, N., Hatsukami, D., Stitzel, J. A., Rice, J., Goate, A. & Bierut, L. J., May 1 2016, In: Molecular Psychiatry. 21, 5, p. 601-607 7 p.

Research output: Contribution to journal › Article › peer-review

Open Access

31 Scopus citations

2015

A genetic risk score combining 32 SNPs is associated with body mass index and improves obesity prediction in people with major depressive disorder

Hung, C. F., Breen, G., Czamara, D., Corre, T., Wolf, C., Kloiber, S., Bergmann, S., Craddock, N., Gill, M., Holsboer, F., Jones, L., Jones, I., Korszun, A., Kutalik, Z., Lucae, S., Maier, W., Mors, O., Owen, M. J., Rice, J. & Rietschel, M. & 10 others, Uher, R., Vollenweider, P., Waeber, G., Craig, I. W., Farmer, A. E., Lewis, C. M., Müller-Myhsok, B., Preisig, M., McGuffin, P. & Rivera, M., Apr 17 2015, In: BMC Medicine. 13, 1, 86.

Research output: Contribution to journal › Article › peer-review

Open Access

54 Scopus citations

Erratum: Novel genetic locus implicated for HIV-1 acquisition with putative regulatory links to HIV replication and infectivity: A genome-wide association study (PLoS ONE (2015) 10:3( e0118149) 10.1371/journal.pone.0118149)

Johnson, E. O., Hancock, D. B., Gaddis, N. C., Levy, J. L., Page, G., Novak, S. P., Glasheen, C., Saccone, N. L., Rice, J. P., Moreau, M. P., Doheny, K. F., Romm, J. M., Brooks, A. I. & Kral, A. H., May 29 2015, In: PloS one. 10, 5, e0129671.

Research output: Contribution to journal › Comment/debate

Open Access

Familiality and SNP heritability of age at onset and episodicity in major depressive disorder

Ferentinos, P., Koukounari, A., Power, R., Rivera, M., Uher, R., Craddock, N., Owen, M. J., Korszun, A., Jones, L., Jones, I., Gill, M., Rice, J. P., Ising, M., Maier, W., Mors, O., Rietschel, M., Preisig, M., Binder, E. B., Aitchison, K. J. & Mendlewicz, J. & 9 others, Souery, D., Hauser, J., Henigsberg, N., Breen, G., Craig, I. W., Farmer, A. E., Müller-Myhsok, B., McGuffin, P. & Lewis, C. M., Jul 30 2015, In: Psychological medicine. 45, 10, p. 2215-2225 11 p.

Research output: Contribution to journal › Article › peer-review

Open Access

22 Scopus citations

Genes associated with alcohol outcomes show enrichment of effects with broad externalizing and impulsivity phenotypes in an independent sample

COGA Investigators, Jan 1 2015, In: Journal of Studies on Alcohol and Drugs. 76, 1, p. 38-46 9 p.

Research output: Contribution to journal › Article › peer-review

Open Access

13 Scopus citations

Genetic studies of body mass index yield new insights for obesity biology

Lifelines Cohort Study & ADIPOGen Consortium; AGEN-BMI Working Group; CARDIOGRAMplusC4D Consortium; CKDGen Consortium; GLGC; ICBP; MAGIC Investigators; MuTHER Consortium; MIGen Consortium; PAGE Consortium; ReproGen Consortium; GENIE Consortium; International Endogene Consortium, Feb 12 2015, In: Nature. 518, 7538, p. 197-206 10 p.

Research output: Contribution to journal › Article › peer-review

Open Access

3184 Scopus citations

Integrating mRNA and miRNA weighted gene co-expression networks with eQTLs in the nucleus accumbens of subjects with alcohol dependence

Mamdani, M., Williamson, V., McMichael, G. O., Blevins, T., Aliev, F., Adkins, A., Hack, L., Bigdeli, T., Van Der Vaart, A. D., Web, B. T., Bacanu, S. A., Kalsi, G., Kendler, K. S., Miles, M. F., Dick, D., Riley, B. P., Dumur, C., Vladimirov, V. I., Hesselbrock, V. & Edenberg, H. J. & 29 others, Nurnberger, J., Foroud, T., Kuperman, S., Kramer, J., Porjesz, B., Bierut, L., Goate, A., Rice, J., Bucholz, K., Schuckit, M., Tischfield, J., Almasy, L., Taylor, R., Dick, D., Bauer, L., Koller, D., O'Connor, S., Wetherill, L., Xuei, X., Chan, G., Kang, S., Manz, N., Rangaswamy, M., Rohrbaugh, J., Wang, J. C., Brooks, A., Aliev, F., Parsian, A. & Reilly, M., Sep 18 2015, In: PloS one. 10, 9, e0137671.

Research output: Contribution to journal › Article › peer-review

Open Access

65 Scopus citations

Joint analysis of psychiatric disorders increases accuracy of risk prediction for schizophrenia, bipolar disorder, and major depressive disorder

Cross-Disorder Working Group of the Psychiatric Genomics Consortium, Feb 5 2015, In: American journal of human genetics. 96, 2, p. 283-294 12 p.

Research output: Contribution to journal › Article › peer-review

Open Access

177 Scopus citations

New genetic loci link adipose and insulin biology to body fat distribution

ADIPOGen Consortium; CARDIOGRAMplusC4D Consortium; CKDGen Consortium; GEFOS Consortium; GENIE Consortium; GLGC; ICBP; International Endogene Consortium; LifeLines Cohort Study; MAGIC Investigators; MuTHER Consortium; PAGE Consortium; ReproGen Consortium, Feb 12 2015, In: Nature. 518, 7538, p. 187-196 10 p.

Research output: Contribution to journal › Article › peer-review

Open Access

1144 Scopus citations

Novel genetic locus implicated for HIV-1 acquisition with putative regulatory links to HIV replication and infectivity: A genome-wide association study

Johnson, E. O., Hancock, D. B., Gaddis, N. C., Levy, J. L., Page, G., Novak, S. P., Glasheen, C., Saccone, N. L., Rice, J. P., Moreau, M. P., Doheny, K. F., Romm, J. M., Brooks, A. I., Aouizerat, B. E., Bierut, L. J. & Kral, A. H., Mar 18 2015, In: PloS one. 10, 3, e0118149.

Research output: Contribution to journal › Article › peer-review

Open Access

18 Scopus citations

Psychiatric genome-wide association study analyses implicate neuronal, immune and histone pathways

The Network and Pathway Analysis Subgroup of the Psychiatric Genomics Consortium & International Inflammatory Bowel Disease Genetics Consortium (IIBDGC), Feb 17 2015, In: Nature neuroscience. 18, 2, p. 199-209 11 p.

Research output: Contribution to journal › Article › peer-review

Open Access

577 Scopus citations

The association between lower educational attainment and depression owing to shared genetic effects? Results in ∼25 000 subjects

Peyrot, W. J., Lee, S. H., Milaneschi, Y., Abdellaoui, A., Byrne, E. M., Esko, T., De Geus, E. J. C., Hemani, G., Hottenga, J. J., Kloiber, S., Levinson, D. F., Lucae, S., Martin, N. G., Medland, S. E., Metspalu, A., Milani, L., Noethen, M. M., Potash, J. B., Rietschel, M. & Rietveld, C. A. & 300 others, Ripke, S., Shi, J., Willemsen, G., Zhu, Z., Boomsma, D. I., Wray, N. R., Penninx, B. W. J. H., Lewis, C. M., Hamilton, S. P., Weissman, M. M., Breen, G., Blackwood, D. H., Cichon, S., Heath, A. C., Holsboer, F., Madden, P. A., McGuffin, P., Muglia, P., Pergadia, M. L., Lin, D., Müller-Myhsok, B., Steinberg, S., Grabe, H. J., Lichtenstein, P., Magnusson, P., Perlis, R. H., Preisig, M., Smoller, J. W., Stefansson, K., Uher, R., Kutalik, Z., Tansey, K. E., Teumer, A., Viktorin, A., Barnes, M. R., Bettecken, T., Binder, E. B., Breuer, R., Castro, V. M., Churchill, S. E., Coryell, W. H., Craddock, N., Craig, I. W., Czamara, D., Degenhardt, F., Farmer, A. E., Fava, M., Frank, J., Gainer, V. S., Gallagher, P. J., Gordon, S. D., Goryachev, S., Gross, M., Guipponi, M., Henders, A. K., Herms, S., Hickie, I. B., Hoefels, S., Hoogendijk, W., Iosifescu, D. V., Ising, M., Jones, I., Jones, L., Jung-Ying, T., Knowles, J. A., Kohane, I. S., Kohli, M. A., Korszun, A., Landen, M., Lawson, W. B., Lewis, G., Macintyre, D., Maier, W., Mattheisen, M., McGrath, P. J., McIntosh, A., McLean, A., Middeldorp, C. M., Middleton, L., Montgomery, G. M., Murphy, S. N., Nauck, M., Nolen, W. A., Nyholt, D. R., O'Donovan, M., Oskarsson, H., Pedersen, N., Scheftner, W. A., Schulz, A., Schulze, T. G., Shyn, S. I., Sigurdsson, E., Slager, S. L., Smit, J. H., Stefansson, H., Steffens, M., Thorgeirsson, T., Tozzi, F., Treutlein, J., Uhr, M., Van Den Oord, E. J., Van Grootheest, G., Völzke, H., Weilburg, J. B., Willemsen, G., Zitman, F. G., Neale, B., Daly, M., Sullivan, P. F., Agrawal, A., Albrecht, E., Z Alizadeh, B., Allik, J., Amin, N., Attia, J. R., Bandinelli, S., Barnard, J., Bastardot, F., E Baumeister, S., Beauchamp, J., Benjamin, D. J., Benke, K. S., Bennett, D. A., Berger, K., Bielak, L. F., Bierut, L. J., Boatman, J. A., Boyle, P. A., Bültmann, U., Campbell, H., Cesarini, D., Chabris, C. F., Cherkas, L., Chung, M. K., Conley, D., Cucca, F., Davey-Smith, G., Davies, G., De Andrade, M., De Jager, P. L., De Leeuw, C., De Neve, J. E., Deary, I. J., Dedoussis, G. V., Deloukas, P., Derringer, J., Dimitriou, M., Eiriksdottir, G., Eklund, N., Elderson, M. F., Eriksson, J. G., Evans, D. S., Evans, D. M., Faul, J. D., Fehrmann, R., Ferrucci, L., Fischer, K., Franke, L., Garcia, M. E., Gieger, C., Gjessing, H. K., Groenen, P. J. F., Grönberg, H., Gudnason, V., Hägg, S., Hall, P., Harris, J. R., Harris, J. M., Harris, T. B., Hastie, N. D., Hayward, C., Heath, A. C., Hernandez, D. G., Hoffmann, W., Hofman, A., Hofman, A., Holle, R., Holliday, E. G., Holzapfel, C., Iacono, W. G., Ibrahim-Verbaas, C. A., Illig, T., Ingelsson, E., Jacobsson, B., Järvelin, M. R., Jhun, M. A., Johannesson, M., Joshi, P. K., Jugessur, A., Kaakinen, M., Kähönen, M., Kanoni, S., Kaprio, J., Kardia, S. L. R., Karjalainen, J., Kirkpatrick, R. M., Koellinger, P. D., Kolcic, I., Kowgier, M., Kristiansson, K., Krueger, R. F., Kutalik, Z., Lahti, J., Laibson, D., Latvala, A., Launer, L. J., Lawlor, D. A., Lethimäki, T., Li, J., Lichtenstein, P., Lichtner, P. K., Liewald, D. C., Lin, P., Lind, P. A., Liu, Y., Lohman, K., Loitfelder, M., Madden, P. A., Magnusson, P. K. E., Mäkinen, T. E., Vidal, P. M., Martin, N. W., Masala, M., McGue, M., McMahon, G., Meirelles, O., Meyer, M. N., Mielck, A., Milani, L., Miller, M. B., Montgomery, G. W., Mukherjee, S., Myhre, R., Nuotio, M. L., J Oldmeadow, C., Oostra, B. A., Palmer, L. J., Palotie, A., Perola, M., Petrovic, K. E., Peyser, P. A., Polašek, O., Posthuma, D., Preisig, M., Quaye, L., Räikkönen, K., Raitakari, O. T., Realo, A., Reinmaa, E., Rice, J. P., Ring, S. M., Ripatti, S., Rivadeneira, F., Rizzi, T. S., Rudan, I., Rustichini, A., Salomaa, V., Sarin, A. P., Schlessinger, D., Schmidt, H., Schmidt, R., Scott, R. J., Shakhbazov, K., Smith, A. V., Smith, J. A., Snieder, H., St Pourcain, B., Starr, J. M., Sul, J. H., Surakka, I., Svento, R., Tanaka, T., Terracciano, A., Teumer, A., Thurik, A. R., Tiemeier, H., Timpson, N. J., Uitterlinden, A. G., Van Der Loos, M. J. H. M., Van Duijn, C. M., Van Rooij, F. J. A., Van Wagoner, D. R., Vartiainen, E., Viikari, J., Visscher, P. M., Vitart, V., Vollenweider, P. K., Völzke, H., Vonk, J. M., Waeber, G., Weir, D. R., Wellmann, J., Westra, H. J., Wichmann, H. E., Widen, E., Wilson, J. F., Wright, A. F., Yang, J., Yu, L. & Zhao, W., Jun 26 2015, In: Molecular Psychiatry. 20, 6, p. 735-743 9 p.

Research output: Contribution to journal › Article › peer-review

Open Access

57 Scopus citations

2014

An ADH1B variant and peer drinking in progression to adolescent drinking milestones: Evidence of a gene-by-environment interaction

Olfson, E., Edenberg, H. J., Nurnberger, J., Agrawal, A., Bucholz, K. K., Almasy, L. A., Chorlian, D., Dick, D. M., Hesselbrock, V. M., Kramer, J. R., Kuperman, S., Porjesz, B., Schuckit, M. A., Tischfield, J. A., Wang, J. C., Wetherill, L., Foroud, T. M., Rice, J., Goate, A. & Bierut, L. J., Oct 1 2014, In: Alcoholism: Clinical and Experimental Research. 38, 10, p. 2541-2549 9 p.

Research output: Contribution to journal › Article › peer-review

Open Access

32 Scopus citations

Application of noncollapsing methods to the gene-based association test: A comparison study using Genetic Analysis Workshop 18 data

Zhang, T. X., Xie, Y. R. & Rice, J. P., Jun 17 2014, In: BMC Proceedings. 8, S53.

Research output: Contribution to journal › Article › peer-review

Open Access

4 Scopus citations

Genetic relationships between suicide attempts, suicidal ideation and major psychiatric disorders: A genome-wide association and polygenic scoring study

Mullins, N., Perroud, N., Uher, R., Butler, A. W., Cohen-Woods, S., Rivera, M., Malki, K., Euesden, J., Power, R. A., Tansey, K. E., Jones, L., Jones, I., Craddock, N., Owen, M. J., Korszun, A., Gill, M., Mors, O., Preisig, M., Maier, W. & Rietschel, M. & 10 others, Rice, J. P., Müller-Myhsok, B., Binder, E. B., Lucae, S., Ising, M., Craig, I. W., Farmer, A. E., Mcguffin, P., Breen, G. & Lewis, C. M., Jul 2014, In: American Journal of Medical Genetics, Part B: Neuropsychiatric Genetics. 165, 5, p. 428-437 10 p.

Research output: Contribution to journal › Article › peer-review

Open Access

90 Scopus citations

Genome-wide association study identifies new disease loci for isolated clubfoot

Zhang, T. X., Haller, G., Lin, P., Alvarado, D. M., Hecht, J. T., Blanton, S. H., Richards, B. S., Rice, J. P., Dobbs, M. B. & Gurnett, C. A., 2014, In: Journal of Medical Genetics. 51, 5, p. 334-339 6 p.

Research output: Contribution to journal › Article › peer-review

21 Scopus citations

Genome-wide association study of sexual maturation in males and females highlights a role for body mass and menarche loci in male puberty

The ReproGen Consortium, The Early Growth Genetics (EGG) Consortium & The GIANT Consortium, Jan 1 2014, In: Human molecular genetics. 23, 16, p. 4452-4464 13 p.

Research output: Contribution to journal › Article › peer-review

Open Access

74 Scopus citations

Genome-wide survival analysis of age at onset of alcohol dependence in extended high-risk COGA families

Kapoor, M., Wang, J. C., Wetherill, L., Le, N., Bertelsen, S., Hinrichs, A. L., Budde, J., Agrawal, A., Almasy, L., Bucholz, K., Dick, D. M., Harari, O., Xiaoling, X., Hesselbrock, V., Kramer, J., Nurnberger, J. I., Rice, J., Schuckit, M., Tischfield, J. & Porjesz, B. & 4 others, Edenberg, H. J., Bierut, L., Foroud, T. & Goate, A., Sep 1 2014, In: Drug and Alcohol Dependence. 142, p. 56-62 7 p.

Research output: Contribution to journal › Article › peer-review

Open Access

26 Scopus citations

Identification of pathways for bipolar disorder: A meta-analysis

Psychiatric Genomics Consortium Bipolar Group, Jun 1 2014, In: JAMA psychiatry. 71, 6, p. 657-664 8 p.

Research output: Contribution to journal › Article › peer-review

Open Access

183 Scopus citations

Investigating the genetic variation underlying episodicity in major depressive disorder: Suggestive evidence for a bipolar contribution

Ferentinos, P., Rivera, M., Ising, M., Spain, S. L., Cohen-Woods, S., Butler, A. W., Craddock, N., Owen, M. J., Korszun, A., Jones, L., Jones, I., Gill, M., Rice, J. P., Maier, W., Mors, O., Rietschel, M., Lucae, S., Binder, E. B., Preisig, M. & Tozzi, F. & 7 others, Muglia, P., Breen, G., Craig, I. W., Farmer, A. E., Müller-Myhsok, B., McGuffin, P. & Lewis, C. M., Feb 2014, In: Journal of affective disorders. 155, 1, p. 81-89 9 p.

Research output: Contribution to journal › Article › peer-review

18 Scopus citations

Parent-of-origin-specific allelic associations among 106 genomic loci for age at menarche

Perry, J. R. B., Day, F., Elks, C. E., Sulem, P., Thompson, D. J., Ferreira, T., He, C., Chasman, D. I., Esko, T., Thorleifsson, G., Albrecht, E., Ang, W. Q., Corre, T., Cousminer, D. L., Feenstra, B., Franceschini, N., Ganna, A., Johnson, A. D., Kjellqvist, S. & Lunetta, K. L. & 178 others, McMahon, G., Nolte, I. M., Paternoster, L., Porcu, E., Smith, A. V., Stolk, L., Teumer, A., Tšernikova, N., Tikkanen, E., Ulivi, S., Wagner, E. K., Amin, N., Bierut, L. J., Byrne, E. M., Hottenga, J. J., Koller, D. L., Mangino, M., Pers, T. H., Yerges-Armstrong, L. M., Zhao, J. H., Andrulis, I. L., Anton-Culver, H., Atsma, F., Bandinelli, S., Beckmann, M. W., Benitez, J., Blomqvist, C., Bojesen, S. E., Bolla, M. K., Bonanni, B., Brauch, H., Brenner, H., Buring, J. E., Chang-Claude, J., Chanock, S., Chen, J., Chenevix-Trench, G., Collée, J. M., Couch, F. J., Couper, D., Coviello, A. D., Cox, A., Czene, K., D'adamo, A. P., Smith, G. D., De Vivo, I., Demerath, E. W., Dennis, J., Devilee, P., Dieffenbach, A. K., Dunning, A. M., Eiriksdottir, G., Eriksson, J. G., Fasching, P. A., Ferrucci, L., Flesch-Janys, D., Flyger, H., Foroud, T., Franke, L., Garcia, M. E., García-Closas, M., Geller, F., De Geus, E. E. J., Giles, G. G., Gudbjartsson, D. F., Gudnason, V., Guénel, P., Guo, S., Hall, P., Hamann, U., Haring, R., Hartman, C. A., Heath, A. C., Hofman, A., Hooning, M. J., Hopper, J. L., Hu, F. B., Hunter, D. J., Karasik, D., Kiel, D. P., Knight, J. A., Kosma, V. M., Kutalik, Z., Lai, S., Lambrechts, D., Lindblom, A., Mägi, R., Magnusson, P. K., Mannermaa, A., Martin, N. G., Masson, G., McArdle, P. F., McArdle, W. L., Melbye, M., Michailidou, K., Mihailov, E., Milani, L., Milne, R. L., Nevanlinna, H., Neven, P., Nohr, E. A., Oldehinkel, A. J., Oostra, B. A., Palotie, A., Peacock, M., Pedersen, N. L., Peterlongo, P., Peto, J., Pharoah, P. D. P., Postma, D. S., Pouta, A., Pylkäs, K., Radice, P., Ring, S., Rivadeneira, F., Robino, A., Rose, L. M., Rudolph, A., Salomaa, V., Sanna, S., Schlessinger, D., Schmidt, M. K., Southey, M. C., Sovio, U., Stampfer, M. J., Stöckl, D., Storniolo, A. M., Timpson, N. J., Tyrer, J., Visser, J. A., Vollenweider, P., Völzke, H., Waeber, G., Waldenberger, M., Wallaschofski, H., Wang, Q., Willemsen, G., Winqvist, R., Wolffenbuttel, B. H. R., Wright, M. J., Boomsma, D. I., Econs, M. J., Khaw, K. T., Loos, R. J. F., McCarthy, M. I., Montgomery, G. W., Rice, J. P., Streeten, E. A., Thorsteinsdottir, U., Van Duijn, C. M., Alizadeh, B. Z., Bergmann, S., Boerwinkle, E., Boyd, H. A., Crisponi, L., Gasparini, P., Gieger, C., Harris, T. B., Ingelsson, E., Järvelin, M. R., Kraft, P., Lawlor, D., Metspalu, A., Pennell, C. E., Ridker, P. M., Snieder, H., Sørensen, T. I. A., Spector, T. D., Strachan, D. P., Uitterlinden, A. G., Wareham, N. J., Widen, E., Zygmunt, M., Murray, A., Easton, D. F., Stefansson, K., Murabito, J. M. & Ong, K. K., Oct 2 2014, In: Nature. 514, 7520, p. 92-97 6 p.

Research output: Contribution to journal › Article › peer-review

Open Access

431 Scopus citations

John Rice

Research output

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