John Rice

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John Rice

Professor of Mathematics in Psychiatry, Professor of Biostatistics, Professor of Genetics

 https://orcid.org/0000-0002-2765-3824

    Willing to Mentor

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    PhD/MSTP Students

    • 42060
      Citations
    1978 …2023

    Research activity per year

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    Search results

    • Functional impact of global rare copy number variation in autism spectrum disorders

      Pinto, D., Pagnamenta, A. T., Klei, L., Anney, R., Merico, D., Regan, R., Conroy, J., Magalhaes, T. R., Correia, C., Abrahams, B. S., Almeida, J., Bacchelli, E., Bader, G. D., Bailey, A. J., Baird, G., Battaglia, A., Berney, T., Bolshakova, N., Bölte, S., Bolton, P. F., & 157 othersBourgeron, T., Brennan, S., Brian, J., Bryson, S. E., Carson, A. R., Casallo, G., Casey, J., Chung, B. H. Y., Cochrane, L., Corsello, C., Crawford, E. L., Crossett, A., Cytrynbaum, C., Dawson, G., De Jonge, M., Delorme, R., Drmic, I., Duketis, E., Duque, F., Estes, A., Farrar, P., Fernandez, B. A., Folstein, S. E., Fombonne, E., Freitag, C. M., Gilbert, J., Gillberg, C., Glessner, J. T., Goldberg, J., Green, A., Green, J., Guter, S. J., Hakonarson, H., Heron, E. A., Hill, M., Holt, R., Howe, J. L., Hughes, G., Hus, V., Igliozzi, R., Kim, C., Klauck, S. M., Kolevzon, A., Korvatska, O., Kustanovich, V., Lajonchere, C. M., Lamb, J. A., Laskawiec, M., Leboyer, M., Le Couteur, A., Leventhal, B. L., Lionel, A. C., Liu, X. Q., Lord, C., Lotspeich, L., Lund, S. C., Maestrini, E., Mahoney, W., Mantoulan, C., Marshall, C. R., McConachie, H., McDougle, C. J., McGrath, J., McMahon, W. M., Merikangas, A., Migita, O., Minshew, N. J., Mirza, G. K., Munson, J., Nelson, S. F., Noakes, C., Noor, A., Nygren, G., Oliveira, G., Papanikolaou, K., Parr, J. R., Parrini, B., Paton, T., Pickles, A., Pilorge, M., Piven, J., Ponting, C. P., Posey, D. J., Poustka, A., Poustka, F., Prasad, A., Ragoussis, J., Renshaw, K., Rickaby, J., Roberts, W., Roeder, K., Roge, B., Rutter, M. L., Bierut, L. J., Rice, J. P., Salt, J., Sansom, K., Sato, D., Segurado, R., Sequeira, A. F., Senman, L., Shah, N., Sheffield, V. C., Soorya, L., Sousa, I., Stein, O., Sykes, N., Stoppioni, V., Strawbridge, C., Tancredi, R., Tansey, K., Thiruvahindrapduram, B., Thompson, A. P., Thomson, S., Tryfon, A., Tsiantis, J., Van Engeland, H., Vincent, J. B., Volkmar, F., Wallace, S., Wang, K., Wang, Z., Wassink, T. H., Webber, C., Weksberg, R., Wing, K., Wittemeyer, K., Wood, S., Wu, J., Yaspan, B. L., Zurawiecki, D., Zwaigenbaum, L., Buxbaum, J. D., Cantor, R. M., Cook, E. H., Coon, H., Cuccaro, M. L., Devlin, B., Ennis, S., Gallagher, L., Geschwind, D. H., Gill, M., Haines, J. L., Hallmayer, J., Miller, J., Monaco, A. P., Nurnberger, J. I., Paterson, A. D., Pericak-Vance, M. A., Schellenberg, G. D., Szatmari, P., Vicente, A. M., Vieland, V. J., Wijsman, E. M., Scherer, S. W., Sutcliffe, J. S. & Betancur, C., Jul 15 2010, In: Nature. 466, 7304, p. 368-372 5 p.

      Research output: Contribution to journal › Article › peer-review

      Open Access
      1155 Scopus citations

    • Functional variant in a bitter-taste receptor (hTAS2R16) influences risk of alcohol dependence

      Hinrichs, A. L., Wang, J. C., Bufe, B., Kwon, J. M., Budde, J., Allen, R., Bertelsen, S., Evans, W., Dick, D., Rice, J., Foroud, T., Nurnberger, J., Tischfield, J. A., Kuperman, S., Crowe, R., Hesselbrock, V., Schuckit, M., Almasy, L., Porjesz, B., Edenberg, H. J., & 4 othersBegleiter, H., Meyerhof, W., Bierut, L. J. & Goate, A. M., Jan 2006, In: American journal of human genetics. 78, 1, p. 103-111 9 p.

      Research output: Contribution to journal › Article › peer-review

      Open Access
      87 Scopus citations

    • Functional variants in TAS2R38 and TAS2R16 influence alcohol consumption in high-risk families of African-American origin

      Wang, J. C., Hinrichs, A. L., Bertelsen, S., Stock, H., Budde, J. P., Dick, D. M., Bucholz, K. K., Rice, J., Saccone, N., Edenberg, H. J., Hesselbrock, V., Kuperman, S., Schuckit, M. A., Bierut, L. J. & Goate, A. M., Feb 2007, In: Alcoholism: Clinical and Experimental Research. 31, 2, p. 209-215 7 p.

      Research output: Contribution to journal › Article › peer-review

      89 Scopus citations

    • Further analyses of the NIMH bipolar dataset: Follow up on suggestive linkage results on 1p and 10p

      Corbett, J., Rice, J., Saccone, N., Goate, A., Reich, T., Foroud, T., Nurnberger, J., Edenberg, H., DePaulo, J. R. & Gershon, E., Aug 7 2000, In: American Journal of Medical Genetics - Neuropsychiatric Genetics. 96, 4, p. 469 1 p.

      Research output: Contribution to journal › Article › peer-review

    • Further evidence for an association between the gamma-aminobutyric acid receptor A, subunit 4 genes on chromosome 4 and Fagerström Test for Nicotine Dependence

      Agrawal, A., Pergadia, M. L., Balasubramanian, S., Saccone, S. F., Hinrichs, A. L., Saccone, N. L., Breslau, N., Johnson, E. O., Hatsukami, D., Martin, N. G., Montgomery, G. W., Goate, A. M., Rice, J. P., Bierut, L. J. & Madden, P. A. F., Mar 2009, In: Addiction. 104, 3, p. 471-477 7 p.

      Research output: Contribution to journal › Article › peer-review

      21 Scopus citations

    • Gamma-aminobutyric acid receptor genes and nicotine dependence: Evidence for association from a case-control study

      Agrawal, A., Pergadia, M. L., Saccone, S. F., Hinrichs, A. L., Lessov-Schlaggar, C. N., Saccone, N. L., Neuman, R. J., Breslau, N., Johnson, E., Hatsukami, D., Montgomery, G. W., Heath, A. C., Martin, N. G., Goate, A. M., Rice, J. P., Bierut, L. J. & Madden, P. A. F., Jun 2008, In: Addiction. 103, 6, p. 1027-1038 12 p.

      Research output: Contribution to journal › Article › peer-review

      42 Scopus citations

    • General causal models for sex differences in the familial transmission of multifactorial traits: An application to human spatial visualizing ability

      Rice, J., Cloninger, R. & Reich, T., 1980, In: Social biology. 27, 1, p. 36-47 12 p.

      Research output: Contribution to journal › Article › peer-review

      11 Scopus citations

    • Genes associated with alcohol outcomes show enrichment of effects with broad externalizing and impulsivity phenotypes in an independent sample

      COGA Investigators, Jan 1 2015, In: Journal of Studies on Alcohol and Drugs. 76, 1, p. 38-46 9 p.

      Research output: Contribution to journal › Article › peer-review

      11 Scopus citations

    • Genetic analysis of bipolar disorder: Summary of GAW10

      Rice, J., 1997, In: Genetic Epidemiology. 14, 6, p. 549-561 13 p.

      Research output: Contribution to journal › Article › peer-review

    • Genetic analysis of kifafa, a complex familial seizure disorder

      Neuman, R. J., Kwon, J. M., Jilek-Aall, L., Rwiza, H. T., Rice, J. P. & Goodfellow, P. J., 1995, In: American journal of human genetics. 57, 4, p. 902-910 9 p.

      Research output: Contribution to journal › Article › peer-review

      15 Scopus citations

    • Genetic analysis of maximum cigarette-use phenotypes.

      Saccone, N. L., Neuman, R. J., Saccone, S. F. & Rice, J. P., 2003, In: BMC genetics. 4 Suppl 1

      Research output: Contribution to journal › Article › peer-review

      Open Access
      2 Scopus citations

    • Genetic analysis of the affective disorders: Summary of GAW5

      Rice, J. & Risch, N., 1989, In: Genetic Epidemiology. 6, 1, p. 161-177 17 p.

      Research output: Contribution to journal › Article › peer-review

      11 Scopus citations

    • Genetic analysis of the maximum drinks phenotype

      Saccone, S. F., Saccone, N. L., Neuman, R. J. & Rice, J. P., Dec 30 2005, In: BMC genetics. 6, SUPPL.1, S124.

      Research output: Contribution to journal › Article › peer-review

      Open Access
      17 Scopus citations

    • Genetic Analysis Workshop 13: Introduction to Workshop Summaries

      Almasy, L., Cupples, L. A., Daw, E. W., Levy, D., Thomas, D., Rice, J. P., Santangelo, S. & MacCluer, J. W., 2003, In: Genetic Epidemiology. 25, SUPPL. 1, p. S1-S4

      Research output: Contribution to journal › Article › peer-review

      Open Access
      6 Scopus citations

    • Genetic and neurophysiological correlates of the age of onset of alcohol use disorders in adolescents and young adults

      Chorlian, D. B., Rangaswamy, M., Manz, N., Wang, J. C., Dick, D., Almasy, L., Bauer, L., Bucholz, K., Foroud, T., Hesselbrock, V., Kang, S. J., Kramer, J., Kuperman, S., Nurnberger, J., Rice, J., Schuckit, M., Tischfield, J., Edenberg, H. J., Goate, A., Bierut, L., & 1 othersPorjesz, B., Sep 2013, In: Behavior genetics. 43, 5, p. 386-401 16 p.

      Research output: Contribution to journal › Article › peer-review

      21 Scopus citations

    • Genetic association of bipolar disorder with the β3 nicotinic receptor subunit gene

      Hartz, S. M., Lin, P., Edenberg, H. J., Xuei, X., Rochberg, N., Saccone, S., Berrettini, W., Nelson, E., Nurnberger, J., Bierut, L. J., Rice, J. P., Miller, M. J., Bowman, E. S., Rau, N. L., Moe, P. R., Samavedy, N., El-Mallakh, R., Manji, H., Glitz, D. A., Meyer, E. T., & 42 othersSmiley, C., Foroud, T., Flury, L., Dick, D. M., Reich, T., Goate, A., McInnis, M., DePaulo, J. R., MacKinnon, D. F., Mondimore, F. M., Potash, J. B., Zandi, P. P., Avramopoulos, D., Payne, J., Byerley, W., Vinogradov, S., Coryell, W., Crowe, R., Gershon, E., Badner, J., McMahon, F., Liu, C., Sanders, A., Caserta, M., Dinwiddie, S., Nguyen, T., Harakal, D., Kelsoe, J., McKinney, R., Scheftner, W., Kravitz, H. M., Marta, D., Vaughn-Brown, A., Bederow, L., McMahon, F. J., Kassem, L., Detera-Wadleigh, S., Austin, L., Murphy, D. L., Lawson, W. B., Nwulia, E. & Hipolito, M., Apr 2011, In: Psychiatric genetics. 21, 2, p. 77-84 8 p.

      Research output: Contribution to journal › Article › peer-review

      9 Scopus citations

    • Genetic association of major depression with a typical features and obesity-related immunometabolic dysregulations

      CHARGE InflammationWorking Group and the Major Depressive DisorderWorking Group of the Psychiatric Genomics Consortium, Dec 2017, In: JAMA psychiatry. 74, 12, p. 1214-1225 12 p.

      Research output: Contribution to journal › Article › peer-review

      Open Access
      128 Scopus citations

    • Genetic diversity fuels gene discovery for tobacco and alcohol use

      23andMe Research Team, the BioBank Japan Project, Gu, C. C., Rice, J. P., Saccone, N. L. & Bierut, L. J., Dec 22 2022, In: Nature. 612, 7941, p. 720-724 5 p.

      Research output: Contribution to journal › Article › peer-review

      Open Access
      8 Scopus citations

    • Genetic effects influencing risk for major depressive disorder in China and Europe

      on behalf of the CONVERGE consortium and Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium, 2017, In: Translational psychiatry. 7, 3, e1074.

      Research output: Contribution to journal › Article › peer-review

      Open Access
      45 Scopus citations

    • Genetic linkage and complex diseases: A comment

      Suarez, B. K., Reich, T., Rice, J. P. & Cloninger, C. R., 1990, In: Genetic Epidemiology. 7, 1, p. 37-40 4 p.

      Research output: Contribution to journal › Article › peer-review

    • Genetic linkage findings for DSM-IV nicotine withdrawal in two populations

      Pergadia, M. L., Agrawal, A., Loukola, A., Montgomery, G. W., Broms, U., Saccone, S. F., Wang, J. C., Todorov, A. A., Heikkilä, K., Statham, D. J., Henders, A. K., Campbell, M. J., Rice, J. P., Todd, R. D., Heath, A. C., Goate, A. M., Peltonen, L., Kaprio, J., Martin, N. G. & Madden, P. A. F., Oct 5 2009, In: American Journal of Medical Genetics, Part B: Neuropsychiatric Genetics. 150, 7, p. 950-959 10 p.

      Research output: Contribution to journal › Article › peer-review

      17 Scopus citations

    • Genetic linkage to chromosome 22q12 for a heavy-smoking quantitative trait in two independent samples

      Saccone, S. F., Pergadia, M. L., Loukola, A., Broms, U., Montgomery, G. W., Wang, J. C., Agrawal, A., Dick, D. M., Heath, A. C., Todorov, A. A., Maunu, H., Heikkilä, K., Morley, K. I., Rice, J. P., Todd, R. D., Kaprio, J., Peltonen, L., Martin, N. G., Goate, A. M. & Madden, P. A. F., May 2007, In: American journal of human genetics. 80, 5, p. 856-866 11 p.

      Research output: Contribution to journal › Article › peer-review

      Open Access
      16 Scopus citations

    • Genetic nurture effects for alcohol use disorder

      COGA Collaborators, Thomas, N. S., Salvatore, J. E., Kuo, S. I. C., Aliev, F., McCutcheon, V. V., Meyers, J. M., Bucholz, K. K., Brislin, S. J., Chan, G., Edenberg, H. J., Kamarajan, C., Kramer, J. R., Kuperman, S., Pandey, G., Plawecki, M. H., Schuckit, M. A., Dick, D. M., Porjesz, B., Hesselbrock, V., & 12 othersForoud, T., Agrawal, A., Liu, Y., Pandey, A., Bierut, L., Rice, J., Tischfield, J., Hart, R., Almasy, L., Goate, A., Slesinger, P. & Scott, D., Feb 2023, In: Molecular Psychiatry. 28, 2, p. 759-766 8 p.

      Research output: Contribution to journal › Article › peer-review

      1 Scopus citations

    • Genetic Overlap Between Attention-Deficit/Hyperactivity Disorder and Bipolar Disorder: Evidence From Genome-wide Association Study Meta-analysis

      PGC ADHD Working Group & PGC Bipolar Disorder Working Group, Nov 1 2017, In: Biological Psychiatry. 82, 9, p. 634-641 8 p.

      Research output: Contribution to journal › Article › peer-review

      80 Scopus citations

    • Genetic relationship between five psychiatric disorders estimated from genome-wide SNPs

      Lee, S. H., Ripke, S., Neale, B. M., Faraone, S. V., Purcell, S. M., Perlis, R. H., Mowry, B. J., Thapar, A., Goddard, M. E., Witte, J. S., Absher, D., Agartz, I., Akil, H., Amin, F., Andreassen, O. A., Anjorin, A., Anney, R., Anttila, V., Arking, D. E., Asherson, P., & 350 othersAzevedo, M. H., Backlund, L., Badner, J. A., Bailey, A. J., Banaschewski, T., Barchas, J. D., Barnes, M. R., Barrett, T. B., Bass, N., Battaglia, A., Bauer, M., Bayés, M., Bellivier, F., Bergen, S. E., Berrettini, W., Betancur, C., Bettecken, T., Biederman, J., Binder, E. B., Black, D. W., Blackwood, D. H. R., Bloss, C. S., Boehnke, M., Boomsma, D. I., Breen, G., Breuer, R., Bruggeman, R., Cormican, P., Buccola, N. G., Buitelaar, J. K., Bunney, W. E., Buxbaum, J. D., Byerley, W. F., Byrne, E. M., Caesar, S., Cahn, W., Cantor, R. M., Casas, M., Chakravarti, A., Chambert, K., Choudhury, K., Cichon, S., Cloninger, C. R., Collier, D. A., Cook, E. H., Coon, H., Cormand, B., Corvin, A., Coryell, W. H., Craig, D. W., Craig, I. W., Crosbie, J., Cuccaro, M. L., Curtis, D., Czamara, D., Datta, S., Dawson, G., Day, R., De Geus, E. J., Degenhardt, F., Djurovic, S., Donohoe, G. J., Doyle, A. E., Duan, J., Dudbridge, F., Duketis, E., Ebstein, R. P., Edenberg, H. J., Elia, J., Ennis, S., Etain, B., Fanous, A., Farmer, A. E., Ferrier, I. N., Flickinger, M., Fombonne, E., Foroud, T., Frank, J., Franke, B., Fraser, C., Freedman, R., Freimer, N. B., Freitag, C. M., Friedl, M., Frisén, L., Gallagher, L., Gejman, P. V., Georgieva, L., Gershon, E. S., Geschwind, D. H., Giegling, I., Gill, M., Gordon, S. D., Gordon-Smith, K., Green, E. K., Greenwood, T. A., Grice, D. E., Gross, M., Grozeva, D., Guan, W., Gurling, H., De Haan, L., Haines, J. L., Hakonarson, H., Hallmayer, J., Hamilton, S. P., Hamshere, M. L., Hansen, T. F., Hartmann, A. M., Hautzinger, M., Heath, A. C., Henders, A. K., Herms, S., Hickie, I. B., Hipolito, M., Hoefels, S., Holmans, P. A., Holsboer, F., Hoogendijk, W. J., Hottenga, J. J., Hultman, C. M., Hus, V., Ingason, A., Ising, M., Jamain, S., Jones, E. G., Jones, I., Jones, L., Tzeng, J. Y., Kähler, A. K., Kahn, R. S., Kandaswamy, R., Keller, M. C., Kennedy, J. L., Kenny, E., Kent, L., Kim, Y., Kirov, G. K., Klauck, S. M., Klei, L., Knowles, J. A., Kohli, M. A., Koller, D. L., Konte, B., Korszun, A., Krabbendam, L., Krasucki, R., Kuntsi, J., Kwan, P., Landén, M., Långström, N., Lathrop, M., Lawrence, J., Lawson, W. B., Leboyer, M., Ledbetter, D. H., Lee, P. H., Lencz, T., Lesch, K. P., Levinson, D. F., Lewis, C. M., Li, J., Lichtenstein, P., Lieberman, J. A., Lin, D. Y., Linszen, D. H., Liu, C., Lohoff, F. W., Loo, S. K., Lord, C., Lowe, J. K., Lucae, S., Macintyre, D. J., Madden, P. A. F., Maestrini, E., Magnusson, P. K. E., Mahon, P. B., Maier, W., Malhotra, A. K., Mane, S. M., Martin, C. L., Martin, N. G., Mattheisen, M., Matthews, K., Mattingsdal, M., Mccarroll, S. A., Mcghee, K. A., Mcgough, J. J., Mcgrath, P. J., Mcguffin, P., Mcinnis, M. G., Mcintosh, A., Mckinney, R., Mclean, A. W., Mcmahon, F. J., Mcmahon, W. M., Mcquillin, A., Medeiros, H., Medland, S. E., Meier, S., Melle, I., Meng, F., Meyer, J., Middeldorp, C. M., Middleton, L., Milanova, V., Miranda, A., Monaco, A. P., Montgomery, G. W., Moran, J. L., Moreno-De-Luca, D., Morken, G., Morris, D. W., Morrow, E. M., Moskvina, V., Muglia, P., Mühleisen, T. W., Muir, W. J., Müller-Myhsok, B., Murtha, M., Myers, R. M., Myin-Germeys, I., Neale, M. C., Nelson, S. F., Nievergelt, C. M., Nikolov, I., Nimgaonkar, V., Nolen, W. A., Nöthen, M. M., Nurnberger, J. I., Nwulia, E. A., Nyholt, D. R., O'dushlaine, C., Oades, R. D., Olincy, A., Oliveira, G., Olsen, L., Ophoff, R. A., Osby, U., Owen, M. J., Palotie, A., Parr, J. R., Paterson, A. D., Pato, C. N., Pato, M. T., Penninx, B. W., Pergadia, M. L., Pericak-Vance, M. A., Pickard, B. S., Pimm, J., Piven, J., Posthuma, D., Potash, J. B., Poustka, F., Propping, P., Puri, V., Quested, D. J., Quinn, E. M., Ramos-Quiroga, J. A., Rasmussen, H. B., Raychaudhuri, S., Rehnström, K., Reif, A., Ribasés, M., Rice, J. P., Rietschel, M., Roeder, K., Roeyers, H., Rossin, L., Rothenberger, A., Rouleau, G., Ruderfer, D., Rujescu, D., Sanders, A. R., Sanders, S. J., Santangelo, S. L., Sergeant, J. A., Schachar, R., Schalling, M., Schatzberg, A. F., Scheftner, W. A., Schellenberg, G. D., Scherer, S. W., Schork, N. J., Schulze, T. G., Schumacher, J., Schwarz, M., Scolnick, E., Scott, L. J., Shi, J., Shilling, P. D., Shyn, S. I., Silverman, J. M., Slager, S. L., Smalley, S. L., Smit, J. H., Smith, E. N., Sonuga-Barke, E. J. S., St. Clair, D., State, M., Steffens, M., Steinhausen, H. C., Strauss, J. S., Strohmaier, J., Stroup, T. S., Sutcliffe, J. S., Szatmari, P., Szelinger, S., Thirumalai, S., Thompson, R. C., Todorov, A. A., Tozzi, F., Treutlein, J., Uhr, M., Van Den Oord, E. J. C. G., Van Grootheest, G., Van Os, J., Vicente, A. M., Vieland, V. J., Vincent, J. B., Visscher, P. M., Walsh, C. A., Wassink, T. H., Watson, S. J., Weissman, M. M., Werge, T., Wienker, T. F., Wijsman, E. M., Willemsen, G., Williams, N., Willsey, A. J., Witt, S. H., Xu, W., Young, A. H., Yu, T. W., Zammit, S., Zandi, P. P., Zhang, P., Zitman, F. G., Zöllner, S., Devlin, B., Kelsoe, J. R., Sklar, P., Daly, M. J., O'donovan, M. C., Craddock, N., Sullivan, P. F., Smoller, J. W., Kendler, K. S. & Wray, N. R., Sep 2013, In: Nature Genetics. 45, 9, p. 984-994 11 p.

      Research output: Contribution to journal › Article › peer-review

      1614 Scopus citations

    • Genetic relationships between suicide attempts, suicidal ideation and major psychiatric disorders: A genome-wide association and polygenic scoring study

      Mullins, N., Perroud, N., Uher, R., Butler, A. W., Cohen-Woods, S., Rivera, M., Malki, K., Euesden, J., Power, R. A., Tansey, K. E., Jones, L., Jones, I., Craddock, N., Owen, M. J., Korszun, A., Gill, M., Mors, O., Preisig, M., Maier, W., Rietschel, M., & 10 othersRice, J. P., Müller-Myhsok, B., Binder, E. B., Lucae, S., Ising, M., Craig, I. W., Farmer, A. E., Mcguffin, P., Breen, G. & Lewis, C. M., Jul 2014, In: American Journal of Medical Genetics, Part B: Neuropsychiatric Genetics. 165, 5, p. 428-437 10 p.

      Research output: Contribution to journal › Article › peer-review

      84 Scopus citations

    • Genetics and personality temperament: Simplicity or complexity?

      Carey, G. & Rice, J., Jan 1983, In: Behavior genetics. 13, 1, p. 43-63 21 p.

      Research output: Contribution to journal › Article › peer-review

      1 Scopus citations

    • Genetic studies of body mass index yield new insights for obesity biology

      Lifelines Cohort Study & ADIPOGen Consortium; AGEN-BMI Working Group; CARDIOGRAMplusC4D Consortium; CKDGen Consortium; GLGC; ICBP; MAGIC Investigators; MuTHER Consortium; MIGen Consortium; PAGE Consortium; ReproGen Consortium; GENIE Consortium; International Endogene Consortium, Feb 12 2015, In: Nature. 518, 7538, p. 197-206 10 p.

      Research output: Contribution to journal › Article › peer-review

      2753 Scopus citations

    • Genetic variation in the CHRNA5 gene affects mRNA levels and is associated with risk for alcohol dependence

      Wang, J. C., Grucza, R., Cruchaga, C., Hinrichs, A. L., Bertelsen, S., Budde, J. P., Fox, L., Goldstein, E., Reyes, O., Saccone, N., Saccone, S., Xuei, X., Bucholz, K., Kuperman, S., Nurnberger, J., Rice, J. P., Schuckit, M., Tischfield, J., Hesselbrock, V., Porjesz, B., & 3 othersEdenberg, H. J., Bierut, L. J. & Goate, A. M., May 2009, In: Molecular Psychiatry. 14, 5, p. 501-510 10 p.

      Research output: Contribution to journal › Article › peer-review

      Open Access
      105 Scopus citations

    • Genome scan meta-analysis of schizophrenia and bipolar disorder, part III: Bipolar disorder

      Segurado, R., Detera-Wadleigh, S. D., Levinson, D. F., Lewis, C. M., Gill, M., Nurnberger, J. I., Craddock, N., DePaulo, J. R., Baron, M., Gershon, E. S., Ekholm, J., Cichon, S., Turecki, G., Claes, S., Kelsoe, J. R., Schofield, P. R., Badenhop, R. F., Morissette, J., Coon, H., Blackwood, D., & 58 othersMclnnes, L. A., Foroud, T., Edenberg, H. J., Reich, T., Rice, J. P., Goate, A., McInnis, M. G., McMahon, F. J., Badner, J. A., Goldin, L. R., Bennett, P., Willour, V. L., Zandi, P. P., Liu, J., Gilliam, C., Juo, S. H., Berrettini, W. H., Yoshikawa, T., Peltonen, L., Lönnqvist, J., Nöthen, M. M., Schumacher, J., Windemuth, C., Rietschel, M., Propping, P., Maier, W., Alda, M., Grof, P., Rouleau, G. A., Del-Favero, J., Van Broeckhoven, C., Mendlewicz, J., Adolfsson, R., Spence, M. A., Luebbert, H., Adams, L. J., Donald, J. A., Mitchell, P. B., Barden, N., Shink, E., Byerley, W., Muir, W., Visscher, P. M., Macgregor, S., Gurling, H., Kalsi, G., McQuillin, A., Escamilla, M. A., Reus, V. I., Leon, P., Freimer, N. B., Ewald, H., Kruse, T. A., Mors, O., Radhakrishna, U., Blouin, J. L., Antonarakis, S. E. & Akarsu, N., Jul 1 2003, In: American journal of human genetics. 73, 1, p. 49-62 14 p.

      Research output: Contribution to journal › Article › peer-review

      Open Access
      365 Scopus citations

    • Genome screen for platelet monoamine oxidase (MAO) activity

      Saccone, N. L., Rice, J. P., Rochberg, N., Goate, A., Reich, T., Shears, S., Wu, W., Nurnberger, J. I., Foroud, T., Edenberg, H. J. & Li, T. K., Oct 15 1999, In: American Journal of Medical Genetics - Neuropsychiatric Genetics. 88, 5, p. 517-521 5 p.

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      13 Scopus citations

    • Genome-wide association analyses identify 44 risk variants and refine the genetic architecture of major depression

      Wray, N. R., Ripke, S., Mattheisen, M., Trzaskowski, M., Byrne, E. M., Abdellaoui, A., Adams, M. J., Agerbo, E., Air, T. M., Andlauer, T. M. F., Bacanu, S. A., Bækvad-Hansen, M., Beekman, A. F. T., Bigdeli, T. B., Binder, E. B., Blackwood, D. R. H., Bryois, J., Buttenschøn, H. N., Bybjerg-Grauholm, J., Cai, N., & 196 othersCastelao, E., Christensen, J. H., Clarke, T. K., Coleman, J. I. R., Colodro-Conde, L., Couvy-Duchesne, B., Craddock, N., Crawford, G. E., Crowley, C. A., Dashti, H. S., Davies, G., Deary, I. J., Degenhardt, F., Derks, E. M., DIrek, N., Dolan, C. V., Dunn, E. C., Eley, T. C., Eriksson, N., Escott-Price, V., Kiadeh, F. H. F., Finucane, H. K., Forstner, A. J., Frank, J., Gaspar, H. A., Gill, M., Giusti-Rodríguez, P., Goes, F. S., Gordon, S. D., Grove, J., Hall, L. S., Hannon, E., Hansen, C. S., Hansen, T. F., Herms, S., Hickie, I. B., Hoffmann, P., Homuth, G., Horn, C., Hottenga, J. J., Hougaard, D. M., Hu, M., Hyde, C. L., Ising, M., Jansen, R., Jin, F., Jorgenson, E., Knowles, J. A., Kohane, I. S., Kraft, J., Kretzschmar, W. W., Krogh, J., Kutalik, Z., Lane, J. M., Li, Y., Li, Y., Lind, P. A., Liu, X., Lu, L., MacIntyre, D. J., MacKinnon, D. F., Maier, R. M., Maier, W., Marchini, J., Mbarek, H., McGrath, P., McGuffin, P., Medland, S. E., Mehta, DI., Middeldorp, C. M., Mihailov, E., Milaneschi, Y., Milani, L., Mill, J., Mondimore, F. M., Montgomery, G. W., Mostafavi, S., Mullins, N., Nauck, M., Ng, B., Nivard, M. G., Nyholt, D. R., O'Reilly, P. F., Oskarsson, H., Owen, M. J., Painter, J. N., Pedersen, C. B., Pedersen, M. G., Peterson, R. E., Pettersson, E., Peyrot, W. J., Pistis, G., Posthuma, D., Purcell, S. M., Quiroz, J. A., Qvist, P., Rice, J. P., Riley, B. P., Rivera, M., Saeed Mirza, S., Saxena, R., Schoevers, R., Schulte, E. C., Shen, L., Shi, J., Shyn, S. I., Sigurdsson, E., Sinnamon, G. B. C., Smit, J. H., Smith, D. J., Stefansson, H., Steinberg, S., Stockmeier, C. A., Streit, F., Strohmaier, J., Tansey, K. E., Teismann, H., Teumer, A., Thompson, W., Thomson, P. A., Thorgeirsson, T. E., Tian, C., Traylor, M., Treutlein, J., Trubetskoy, V., Uitterlinden, A. G., Umbricht, D., Van Der Auwera, S., Van Hemert, A. M., Viktorin, A., Visscher, P. M., Wang, Y., Webb, B. T., Weinsheimer, S. M., Wellmann, J., Willemsen, G., Witt, S. H., Wu, Y., Xi, H. S., Yang, J., Zhang, F., Arolt, V., Baune, B. T., Berger, K., Boomsma, D. I., Cichon, S., Dannlowski, U., De Geus, E. C. J., Depaulo, J. R., Domenici, E., Domschke, K., Esko, T., Grabe, H. J., Hamilton, S. P., Hayward, C., Heath, A. C., Hinds, D. A., Kendler, K. S., Kloiber, S., Lewis, G., Li, Q. S., Lucae, S., Madden, P. F. A., Magnusson, P. K., Martin, N. G., McIntosh, A. M., Metspalu, A., Mors, O., Mortensen, P. B., Müller-Myhsok, B., Nordentoft, M., Nöthen, M. M., O'Donovan, M. C., Paciga, S. A., Pedersen, N. L., Penninx, B. W. J. H., Perlis, R. H., Porteous, D. J., Potash, J. B., Preisig, M., Rietschel, M., Schaefer, C., Schulze, T. G., Smoller, J. W., Stefansson, K., Tiemeier, H., Uher, R., Völzke, H., Weissman, M. M., Werge, T., Winslow, A. R., Lewis, C. M., Levinson, D. F., Breen, G., Børglum, A. D. & Sullivan, P. F., May 1 2018, In: Nature Genetics. 50, 5, p. 668-681 14 p.

      Research output: Contribution to journal › Article › peer-review

      1371 Scopus citations

    • Genome-wide association analysis accounting for environmental factors through propensity-score matching: Application to stressful live events in major depressive disorder

      Power, R. A., Cohen-Woods, S., Ng, M. Y., Butler, A. W., Craddock, N., Korszun, A., Jones, L., Jones, I., Gill, M., Rice, J. P., Maier, W., Zobel, A., Mors, O., Placentino, A., Rietschel, M., Aitchison, K. J., Tozzi, F., Muglia, P., Breen, G., Farmer, A. E., & 3 othersMcguffin, P., Lewis, C. M. & Uher, R., Sep 2013, In: American Journal of Medical Genetics, Part B: Neuropsychiatric Genetics. 162, 6, p. 521-529 9 p.

      Research output: Contribution to journal › Article › peer-review

      14 Scopus citations

    • Genome-wide association analysis of copy number variation in recurrent depressive disorder

      Rucker, J. J. H., Breen, G., Pinto, D., Pedroso, I., Lewis, C. M., Cohen-Woods, S., Uher, R., Schosser, A., Rivera, M., Aitchison, K. J., Craddock, N., Owen, M. J., Jones, L., Jones, I., Korszun, A., Muglia, P., Barnes, M. R., Preisig, M., Mors, O., Gill, M., & 8 othersMaier, W., Rice, J., Rietschel, M., Holsboer, F., Farmer, A. E., Craig, I. W., Scherer, S. W. & Mcguffin, P., Feb 2013, In: Molecular Psychiatry. 18, 2, p. 183-189 7 p.

      Research output: Contribution to journal › Article › peer-review

      40 Scopus citations

    • Genome-Wide association of bipolar disorder suggests an enrichment of replicable associations in regions near genes

      Smith, E. N., Koller, D. L., Panganiban, C., Szelinger, S., Zhang, P., Badner, J. A., Barrett, T. B., Berrettini, W. H., Bloss, C. S., Byerley, W., Coryell, W., Edenberg, H. J., Foroud, T., Gershon, E. S., Greenwood, T. A., Guo, Y., Hipolito, M., Keating, B. J., Lawson, W. B., Liu, C., & 18 othersMahon, P. B., McInnis, M. G., McMahon, F. J., McKinney, R., Murray, S. S., Nievergelt, C. M., Nurnberger, J. I., Nwulia, E. A., Potash, J. B., Rice, J., Schulze, T. G., Scheftner, W. A., Shilling, P. D., Zandi, P. P., Zöllner, S., Craig, D. W., Schork, N. J. & Kelsoe, J. R., Jun 2011, In: PLoS genetics. 7, 6, e1002134.

      Research output: Contribution to journal › Article › peer-review

      Open Access
      57 Scopus citations

    • Genomewide association scan of suicidal thoughts and behaviour in major depression

      Schosser, A., Butler, A. W., Ising, M., Perroud, N., Uher, R., Ng, M. Y., Cohen-Woods, S., Craddock, N., Owen, M. J., Korszun, A., Jones, L., Jones, I., Gill, M., Rice, J. P., Maier, W., Mors, O., Rietschel, M., Lucae, S., Binder, E. B., Preisig, M., & 10 othersPerry, J., Tozzi, F., Muglia, P., Aitchison, K. J., Breen, G., Craig, I. W., Farmer, A. E., Müller-Myhsok, B., McGuffin, P. & Lewis, C. M., 2011, In: PloS one. 6, 7, e20690.

      Research output: Contribution to journal › Article › peer-review

      Open Access
      90 Scopus citations

    • Genomewide Association Studies: History, Rationale, and Prospects for Psychiatric Disorders

      Cichon, S., Craddock, N., Daly, M., Faraone, S. V., Gejman, P. V., Kelsoe, J., Lehner, T., Levinson, D. F., Moran, A., Sklar, P., Sullivan, P. F., Anney, R., Gill, M., Corvin, A., Buitelaar, J., Franke, B., Elia, J., Hakonarson, H., Kent, L., McGough, J., & 103 othersSmalley, S., Ophoff, R., Mick, E., Santangelo, S., Ferreira, M., Purcell, S., Ruderfer, D., Smoller, J., Perlis, R., Neale, B., Stone, J., Nisenbaum, L., Thapar, A., Moskvina, V., Holmans, P., O'Donovan, M., Owen, M., Todd, R., Todorov, A., Rice, J., Devlin, B., Arking, D., Chakravarti, A., Potash, J. B., Pulver, A., Buxbaum, J. D., Cook, E., Peltonen, L., Suvisaari, J., Piven, J., Lin, D., Sullivan, P., Rouleau, G., Awadalla, P., Schellenberg, G., Scherer, S., Sutcliffe, J., Szatmari, P., Vieland, V., Andreassen, O. A., Frigessi, A., Blackwood, D., Muir, W., Boehnke, M., Burmeister, M., Flickinger, M., Guan, W., Li, J., Scott, L., Breuer, R., Rietschel, M., Schulze, T., Greenwood, T., Schork, N., Gurling, H., Muglia, P., Upmanyu, R., Tozzi, F., Noethen, M., Wienker, T., Steffens, M., Nurnberger, J., Kendler, K., Riley, B., van den Oord, E., Boomsma, D., de Geus, E., Hoogendijk, W., Penninx, B., Willemsen, A. H. M., Posthuma, D., Coryell, W., Hamilton, S., Kloiber, S., Lucae, S., Ripke, S., Lawson, W. B., Lewis, C., McGuffin, P., Martin, N., Wray, N., McGrath, P., Weissman, M. M., Offord, J., Scheftner, W. A., Slager, S., Fanous, A., Hultman, C., Kivikko, S., Laurent, C., Lencz, T., Malhotra, A., Mowry, B., Holliday, E., Sanders, A., Schwab, S., Wildenaver, D., St. Clair, D., Dudbridge, F., Pickering, E., Posthuma, D., Sebat, J. & Tzeng, J. Y., May 2009, In: American Journal of Psychiatry. 166, 5, p. 540-556 17 p.

      Research output: Contribution to journal › Review article › peer-review

      321 Scopus citations

    • Genome-wide association study identifies 30 loci associated with bipolar disorder

      eQTLgen Consortium, BIOS Consortium & the Bipolar Disorder Working Group of the Psychiatric Genomics Consortium, May 1 2019, In: Nature Genetics. 51, 5, p. 793-803 11 p.

      Research output: Contribution to journal › Article › peer-review

      744 Scopus citations

    • Genome-wide association study identifies a novel locus for cannabis dependence

      Agrawal, A., Chou, Y. L., Carey, C. E., Baranger, D. A. A., Zhang, B., Sherva, R., Wetherill, L., Kapoor, M., Wang, J. C., Bertelsen, S., Anokhin, A. P., Hesselbrock, V., Kramer, J., Lynskey, M. T., Meyers, J. L., Nurnberger, J. I., Rice, J. P., Tischfield, J., Bierut, L. J., Degenhardt, L., & 16 othersFarrer, L. A., Gelernter, J., Hariri, A. R., Heath, A. C., Kranzler, H. R., Madden, P. A. F., Martin, N. G., Montgomery, G. W., Porjesz, B., Wang, T., Whitfield, J. B., Edenberg, H. J., Foroud, T., Goate, A. M., Bogdan, R. & Nelson, E. C., May 1 2018, In: Molecular Psychiatry. 23, 5, p. 1293-1302 10 p.

      Research output: Contribution to journal › Article › peer-review

      29 Scopus citations

    • Genome-wide association study identifies new disease loci for isolated clubfoot

      Zhang, T. X., Haller, G., Lin, P., Alvarado, D. M., Hecht, J. T., Blanton, S. H., Richards, B. S., Rice, J. P., Dobbs, M. B. & Gurnett, C. A., 2014, In: Journal of Medical Genetics. 51, 5, p. 334-339 6 p.

      Research output: Contribution to journal › Article › peer-review

      20 Scopus citations

    • Genome-wide association study of 40,000 individuals identifies two novel loci associated with bipolar disorder

      Hou, L., Bergen, S. E., Akula, N., Song, J., Hultman, C. M., Landén, M., Adli, M., Alda, M., Ardau, R., Arias, B., Aubry, J. M., Backlund, L., Badner, J. A., Barrett, T. B., Bauer, M., Baune, B. T., Bellivier, F., Benabarre, A., Bengesser, S., Berrettini, W. H., & 119 othersBhattacharjee, A. K., Biernacka, J. M., Birner, A., Bloss, C. S., Brichant-Petitjean, C., Bui, E. T., Byerley, W., Cervantes, P., Chillotti, C., Cichon, S., Colom, F., Coryell, W., Craig, D. W., Cruceanu, C., Czerski, P. M., Davis, T., Dayer, A., Degenhardt, F., Del Zompo, M., DePaulo, J. R., Edenberg, H. J., Étain, B., Falkai, P., Foroud, T., Forstner, A. J., Frisén, L., Frye, M. A., Fullerton, J. M., Gard, S., Garnham, J. S., Gershon, E. S., Goes, F. S., Greenwood, T. A., Grigoroiu-Serbanescu, M., Hauser, J., Heilbronner, U., Heilmann-Heimbach, S., Herms, S., Hipolito, M., Hitturlingappa, S., Hoffmann, P., Hofmann, A., Jamain, S., Jiménez, E., Kahn, J. P., Kassem, L., Kelsoe, J. R., Kittel-Schneider, S., Kliwicki, S., Koller, D. L., König, B., Lackner, N., Laje, G., Lang, M., Lavebratt, C., Lawson, W. B., Leboyer, M., Leckband, S. G., Liu, C., Maaser, A., Mahon, P. B., Maier, W., Maj, M., Manchia, M., Martinsson, L., McCarthy, M. J., McElroy, S. L., McInnis, M. G., McKinney, R., Mitchell, P. B., Mitjans, M., Mondimore, F. M., Monteleone, P., Mühleisen, T. W., Nievergelt, C. M., Nöthen, M. M., Novák, T., Nurnberger, J. I., Nwulia, E. A., Ösby, U., Pfennig, A., Potash, J. B., Propping, P., Reif, A., Reininghaus, E., Rice, J., Rietschel, M., Rouleau, G. A., Rybakowski, J. K., Schalling, M., Scheftner, W. A., Schofield, P. R., Schork, N. J., Schulze, T. G., Schumacher, J., Schweizer, B. W., Severino, G., Shekhtman, T., Shilling, P. D., Simhandl, C., Slaney, C. M., Smith, E. N., Squassina, A., Stamm, T., Stopkova, P., Streit, F., Strohmaier, J., Szelinger, S., Tighe, S. K., Tortorella, A., Turecki, G., Vieta, E., Volkert, J., Witt, S. H., Wright, A., Zandi, P. P., Zhang, P., Zollner, S. & McMahon, F. J., Aug 1 2016, In: Human molecular genetics. 25, 15, p. 3383-3394 12 p.

      Research output: Contribution to journal › Article › peer-review

      Open Access
      117 Scopus citations

    • Genomewide Association Study of Alcohol Dependence Identifies Risk Loci Altering Ethanol-Response Behaviors in Model Organisms

      Collaborative Study of the Genetics of Alcoholism Consortium & the German Study of the Genetics of Addiction Consortium, May 2017, In: Alcoholism: Clinical and Experimental Research. 41, 5, p. 911-928 18 p.

      Research output: Contribution to journal › Article › peer-review

      34 Scopus citations

    • Genome-wide association study of alcohol dependence implicates a region on chromosome 11

      Edenberg, H. J., Koller, D. L., Xuei, X., Wetherill, L., McClintick, J. N., Almasy, L., Bierut, L. J., Bucholz, K. K., Goate, A., Aliev, F., Dick, D., Hesselbrock, V., Hinrichs, A., Kramer, J., Kuperman, S., Nurnberger, J. I., Rice, J. P., Schuckit, M. A., Taylor, R., Todd Webb, B., & 3 othersTischfield, J. A., Porjesz, B. & Foroud, T., May 2010, In: Alcoholism: Clinical and Experimental Research. 34, 5, p. 840-852 13 p.

      Research output: Contribution to journal › Article › peer-review

      Open Access
      92 Scopus citations

    • Genome-wide association study of bipolar disorder in European American and African American individuals

      Smith, E. N., Bloss, C. S., Badner, J. A., Barrett, T., Belmonte, P. L., Berrettini, W., Byerley, W., Coryell, W., Craig, D., Edenberg, H. J., Eskin, E., Foroud, T., Gershon, E., Greenwood, T. A., Hipolito, M., Koller, D. L., Lawson, W. B., Liu, C., Lohoff, F., McInnis, M. G., & 17 othersMcMahon, F. J., Mirel, D. B., Murray, S. S., Nievergelt, C., Nurnberger, J., Nwulia, E. A., Paschall, J., Potash, J. B., Rice, J., Schulze, T. G., Scheftner, W., Panganiban, C., Zaitlen, N., Zandi, P. P., Zöllner, S., Schork, N. J. & Kelsoe, J. R., Aug 2009, In: Molecular Psychiatry. 14, 8, p. 755-763 9 p.

      Research output: Contribution to journal › Article › peer-review

      93 Scopus citations

    • Genome-wide association study of co-occurring anxiety in major depression

      Schosser, A., Butler, A. W., Uher, R., Ng, M. Y., Cohen-Woods, S., Craddock, N., Owen, M. J., Korszun, A., Gill, M., Rice, J., Hauser, J., Henigsberg, N., Maier, W., Mors, O., Placentino, A., Rietschel, M., Souery, D., Preisig, M., Craig, I. W., Farmer, A. E., & 2 othersLewis, C. M. & McGuffin, P., Dec 2013, In: World Journal of Biological Psychiatry. 14, 8, p. 611-621 11 p.

      Research output: Contribution to journal › Article › peer-review

      14 Scopus citations

    • Genome-wide association study of irritable vs. Elated Mania suggests genetic differences between clinical subtypes of bipolar disorder

      Bipolar Genome Study (BiGS) Consortium, Jan 17 2013, In: PloS one. 8, 1, e53804.

      Research output: Contribution to journal › Article › peer-review

      Open Access
      19 Scopus citations

    • Genome-wide association study of more than 40,000 bipolar disorder cases provides new insights into the underlying biology

      HUNT All-In Psychiatry, Jun 2021, In: Nature Genetics. 53, 6, p. 817-829 13 p.

      Research output: Contribution to journal › Article › peer-review

      243 Scopus citations

    • Genome-wide association study of sexual maturation in males and females highlights a role for body mass and menarche loci in male puberty

      The ReproGen Consortium, The Early Growth Genetics (EGG) Consortium & The GIANT Consortium, Jan 1 2014, In: Human molecular genetics. 23, 16, p. 4452-4464 13 p.

      Research output: Contribution to journal › Article › peer-review

      Open Access
      64 Scopus citations

    • Genome-wide association study of theta band event-related oscillations identifies serotonin receptor gene HTR7 influencing risk of alcohol dependence

      Zlojutro, M., Manz, N., Rangaswamy, M., Xuei, X., Flury-Wetherill, L., Koller, D., Bierut, L. J., Goate, A., Hesselbrock, V., Kuperman, S., Nurnberger, J., Rice, J. P., Schuckit, M. A., Foroud, T., Edenberg, H. J., Porjesz, B. & Almasy, L., Jan 2011, In: American Journal of Medical Genetics, Part B: Neuropsychiatric Genetics. 156, 1, p. 44-58 15 p.

      Research output: Contribution to journal › Article › peer-review

      47 Scopus citations

    • Genome-wide Burden of Rare Short Deletions Is Enriched in Major Depressive Disorder in Four Cohorts

      Zhang, X., Abdellaoui, A., Rucker, J., de Jong, S., Potash, J. B., Weissman, M. M., Shi, J., Knowles, J. A., Pato, C., Pato, M., Sobell, J., Smit, J. H., Hottenga, J. J., de Geus, E. J. C., Lewis, C. M., Buttenschøn, H. N., Craddock, N., Jones, I., Jones, L., McGuffin, P., & 13 othersMors, O., Owen, M. J., Preisig, M., Rietschel, M., Rice, J. P., Rivera, M., Uher, R., Gejman, P. V., Sanders, A. R., Boomsma, D., Penninx, B. W. J. H., Breen, G. & Levinson, D. F., Jun 15 2019, In: Biological Psychiatry. 85, 12, p. 1065-1073 9 p.

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      Open Access
      17 Scopus citations