John Rice

2025

Correction to: Multivariate analysis of 1.5 million people identifies genetic associations with traits related to self-regulation and addiction (Nature Neuroscience, (2021), 24, 10, (1367-1376), 10.1038/s41593-021-00908-3)

COGA Collaborators, Jan 2025, In: Nature neuroscience. 28, 1, p. 213 1 p.

Research output: Contribution to journal › Comment/debate

Open Access

Genomics yields biological and phenotypic insights into bipolar disorder

Genoplan Research Team, Estonian Biobank research team, Bipolar Disorder Working Group of the Psychiatric Genomics Consortium, 23andMe Research Team, Million Veteran Program (MVP), Cooperative Studies Program (CSP) #572, Genomic Psychiatry Cohort (GPC) Investigators, PGC-FG Single cell working group & HUNT All-In Psychiatry, Mar 27 2025, In: Nature. 639, 8056, p. 968-975 8 p., 2417.

Research output: Contribution to journal › Article › peer-review

Open Access

8 Scopus citations

Trans-ancestry genome-wide study of depression identifies 697 associations implicating cell types and pharmacotherapies

Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium, Feb 6 2025, In: Cell. 188, 3, p. 640-652.e9

Research output: Contribution to journal › Article › peer-review

Open Access

3 Scopus citations

2024

Alcohol Use Disorder Polygenic Score Compared with Family History and ADH1B

Lai, D., Zhang, M., Abreu, M., Schwantes-An, T. H., Chan, G., Dick, D. M., Kamarajan, C., Kuang, W., Nurnberger, J. I., Plawecki, M. H., Rice, J., Schuckit, M., Porjesz, B., Liu, Y. & Foroud, T., Dec 30 2024, In: JAMA Network Open. 7, 12, p. e2452705

Research output: Contribution to journal › Article › peer-review

Open Access

Childhood trauma is associated with developmental trajectories of EEG coherence, alcohol-related outcomes, and PTSD symptoms

COGA Investigators, 2024, (Accepted/In press) In: Psychological medicine.

Research output: Contribution to journal › Article › peer-review

Open Access

Potential causal association between gut microbiome and posttraumatic stress disorder

He, Q., Wang, W., Xu, D., Xiong, Y., Tao, C., You, C., Ma, L., Ma, J., Nievergelt, C. M., Maihofer, A. X., Klengel, T., Atkinson, E. G., Chen, C. Y., Choi, K. W., Coleman, J. R. I., Dalvie, S., Duncan, L. E., Logue, M. W., Provost, A. C. & Ratanatharathorn, A. & 165 others, Stein, M. B., Torres, K., Aiello, A. E., Almli, L. M., Amstadter, A. B., Andersen, S. B., Andreassen, O. A., Arbisi, P. A., Ashley-Koch, A. E., Austin, S. B., Avdibegovic, E., Babić, D., Bækvad-Hansen, M., Baker, D. G., Beckham, J. C., Bierut, L. J., Bisson, J. I., Boks, M. P., Bolger, E. A., Børglum, A. D., Bradley, B., Brashear, M., Breen, G., Bryant, R. A., Bustamante, A. C., Bybjerg-Grauholm, J., Calabrese, J. R., Caldas-de-Almeida, J. M., Dale, A. M., Daly, M. J., Daskalakis, N. P., Deckert, J., Delahanty, D. L., Dennis, M. F., Disner, S. G., Domschke, K., Dzubur-Kulenovic, A., Erbes, C. R., Evans, A., Farrer, L. A., Feeny, N. C., Flory, J. D., Forbes, D., Franz, C. E., Galea, S., Garrett, M. E., Gelaye, B., Gelernter, J., Geuze, E., Gillespie, C., Uka, A. G., Gordon, S. D., Guffanti, G., Hammamieh, R., Harnal, S., Hauser, M. A., Heath, A. C., Hemmings, S. M. J., Hougaard, D. M., Jakovljevic, M., Jett, M., Johnson, E. O., Jones, I., Jovanovic, T., Qin, X. J., Junglen, A. G., Karstoft, K. I., Kaufman, M. L., Kessler, R. C., Khan, A., Kimbrel, N. A., King, A. P., Koen, N., Kranzler, H. R., Kremen, W. S., Lawford, B. R., Lebois, L. A. M., Lewis, C. E., Linnstaedt, S. D., Lori, A., Lugonja, B., Luykx, J. J., Lyons, M. J., Maples-Keller, J., Marmar, C., Martin, A. R., Martin, N. G., Maurer, D., Mavissakalian, M. R., McFarlane, A., McGlinchey, R. E., McLaughlin, K. A., McLean, S. A., McLeay, S., Mehta, D., Milberg, W. P., Miller, M. W., Morey, R. A., Morris, C. P., Mors, O., Mortensen, P. B., Neale, B. M., Nelson, E. C., Nordentoft, M., Norman, S. B., O’Donnell, M., Orcutt, H. K., Panizzon, M. S., Peters, E. S., Peterson, A. L., Peverill, M., Pietrzak, R. H., Polusny, M. A., Rice, J. P., Ripke, S., Risbrough, V. B., Roberts, A. L., Rothbaum, A. O., Rothbaum, B. O., Roy-Byrne, P., Ruggiero, K., Rung, A., Rutten, B. P. F., Saccone, N. L., Sanchez, S. E., Schijven, D., Seedat, S., Seligowski, A. V., Seng, J. S., Sheerin, C. M., Silove, D., Smith, A. K., Smoller, J. W., Solovieff, N., Sponheim, S. R., Stein, D. J., Sumner, J. A., Teicher, M. H., Thompson, W. K., Trapido, E., Uddin, M., Ursano, R. J., van den Heuvel, L. L., van Hooff, M., Vermetten, E., Vinkers, C. H., Voisey, J., Wang, Y., Wang, Z., Werge, T., Williams, M. A., Williamson, D. E., Winternitz, S., Wolf, C., Wolf, E. J., Wolff, J. D., Yehuda, R., Young, K. A., Young, R. M. D., Zhao, H., Zoellner, L. A., Liberzon, I., Ressler, K. J., Haas, M. & Koenen, K. C., Dec 2024, In: Translational psychiatry. 14, 1, 67.

Research output: Contribution to journal › Article › peer-review

Open Access

9 Scopus citations

The design of studies for investigating linkage and association

Rice, J. P., Saccone, N. L. & Suarez, B. K., Jan 1 2024, Analysis of Multifactorial Disease. CRC Press, p. 37-62 26 p.

Research output: Chapter in Book/Report/Conference proceeding › Chapter › peer-review

2023

Changes over time in endorsement of 11 DSM-IV alcohol use disorder (AUD) criteria in young adults with persistent or recurrent AUD in The Collaborative Study on the Genetics of Alcoholism

The Collaborative Study on the Genetics of Alcoholism (COGA), May 2023, In: Alcohol: Clinical and Experimental Research. 47, 5, p. 919-929 11 p.

Research output: Contribution to journal › Article › peer-review

Open Access

1 Scopus citations

Genetic nurture effects for alcohol use disorder

COGA Collaborators, Thomas, N. S., Salvatore, J. E., Kuo, S. I. C., Aliev, F., McCutcheon, V. V., Meyers, J. M., Bucholz, K. K., Brislin, S. J., Chan, G., Edenberg, H. J., Kamarajan, C., Kramer, J. R., Kuperman, S., Pandey, G., Plawecki, M. H., Schuckit, M. A., Dick, D. M., Porjesz, B. & Hesselbrock, V. & 12 others, Foroud, T., Agrawal, A., Liu, Y., Pandey, A., Bierut, L., Rice, J., Tischfield, J., Hart, R., Almasy, L., Goate, A., Slesinger, P. & Scott, D., Feb 2023, In: Molecular Psychiatry. 28, 2, p. 759-766 8 p.

Research output: Contribution to journal › Article › peer-review

Open Access

14 Scopus citations

Genetics of vegetarianism: A genome-wide association study

Yaseen, N. R., Barnes, C. L. K., Sun, L., Takeda, A. & Rice, J. P., Oct 2023, In: PloS one. 18, 10 October, e0291305.

Research output: Contribution to journal › Article › peer-review

Open Access

4 Scopus citations

Identification of PROK2 gene polymorphisms as predictors of methamphetamine use disorder risk and indicators of craving scale in the Chinese Han population

Jiang, Z., Zhang, T., Han, W., Xiao, J., Zhang, W., Wang, X., Liu, J., Yang, Y., Yang, C., Guan, F., Li, T. & Rice, J. P., 2023, In: Frontiers in Pharmacology. 14, 1217382.

Research output: Contribution to journal › Article › peer-review

Open Access

2 Scopus citations

Multivariate genome-wide association meta-analysis of over 1 million subjects identifies loci underlying multiple substance use disorders

Substance Use Disorder Working Group of the Psychiatric Genomics Consortium, Mar 2023, In: Nature Mental Health. 1, 3, p. 210-223 14 p., 1499.

Research output: Contribution to journal › Article › peer-review

Open Access

87 Scopus citations

Polygenic risk prediction: why and when out-of-sample prediction R² can exceed SNP-based heritability

Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium, Wang, X., Walker, A., Revez, J. A., Ni, G., Adams, M. J., McIntosh, A. M., Wray, N. R., Ripke, S., Mattheisen, M., Trzaskowski, M., Byrne, E. M., Abdellaoui, A., Agerbo, E., Air, T. M., Andlauer, T. F. M., Bacanu, S. A., Bækvad-Hansen, M., Beekman, A. T. F. & Bigdeli, T. B. & 181 others, Binder, E. B., Bryois, J., Buttenschøn, H. N., Bybjerg-Grauholm, J., Cai, N., Castelao, E., Christensen, J. H., Clarke, T. K., Coleman, J. R. I., Colodro-Conde, L., Couvy-Duchesne, B., Craddock, N., Crawford, G. E., Davies, G., Degenhardt, F., Derks, E. M., Direk, N., Dolan, C. V., Dunn, E. C., Eley, T. C., Escott-Price, V., Kiadeh, F. F. H., Finucane, H. K., Foo, J. C., Forstner, A. J., Frank, J., Gaspar, H. A., Gill, M., Goes, F. S., Gordon, S. D., Grove, J., Hall, L. S., Søholm Hansen, C., Hansen, T. F., Herms, S., Hickie, I. B., Hoffmann, P., Homuth, G., Horn, C., Hottenga, J. J., Hougaard, D. M., Howard, D. M., Ising, M., Jansen, R., Jones, I., Jones, L. A., Jorgenson, E., Knowles, J. A., Kohane, I. S., Kraft, J., Kretzschmar, W. W., Kutalik, Z., Li, Y., Lind, P. A., MacIntyre, D. J., MacKinnon, D. F., Maier, R. M., Maier, W., Marchini, J., Mbarek, H., McGrath, P., McGuffin, P., Medland, S. E., Mehta, D., Middeldorp, C. M., Mihailov, E., Milaneschi, Y., Milani, L., Mondimore, F. M., Montgomery, G. W., Mostafavi, S., Mullins, N., Nauck, M., Ng, B., Nivard, M. G., Nyholt, D. R., O'Reilly, P. F., Oskarsson, H., Owen, M. J., Painter, J. N., Bøcker Pedersen, C., Giørtz Pedersen, M., Peterson, R. E., Peyrot, W. J., Pistis, G., Posthuma, D., Quiroz, J. A., Qvist, P., Rice, J. P., Riley, B. P., Rivera, M., Saeed Mirza, S., Schoevers, R., Schulte, E. C., Shen, L., Shi, J., Shyn, S. I., Sigurdsson, E., Sinnamon, G. C. B., Smit, J. H., Smith, D. J., Stefansson, H., Steinberg, S., Streit, F., Strohmaier, J., Tansey, K. E., Teismann, H., Teumer, A., Thompson, W., Thomson, P. A., Thorgeirsson, T. E., Traylor, M., Treutlein, J., Trubetskoy, V., Uitterlinden, A. G., Umbricht, D., Van der Auwera, S., van Hemert, A. M., Viktorin, A., Visscher, P. M., Wang, Y., Webb, B. T., Weinsheimer, S. M., Wellmann, J., Willemsen, G., Witt, S. H., Wu, Y., Xi, H. S., Yang, J., Zhang, F., Arolt, V., Baune, B. T., Berger, K., Boomsma, D. I., Cichon, S., Dannlowski, U., de Geus, E. J. C., DePaulo, J. R., Domenici, E., Domschke, K., Esko, T., Grabe, H. J., Hamilton, S. P., Hayward, C., Heath, A. C., Kendler, K. S., Kloiber, S., Lewis, G., Li, Q. S., Lucae, S., Madden, P. A. F., Magnusson, P. K., Martin, N. G., Metspalu, A., Mors, O., Bo Mortensen, P., Müller-Myhsok, B., Nordentoft, M., Nöthen, M. M., O'Donovan, M. C., Paciga, S. A., Pedersen, N. L., Penninx, B. W. J. H., Perlis, R. H., Porteous, D. J., Potash, J. B., Preisig, M., Rietschel, M., Schaefer, C., Schulze, T. G., Smoller, J. W., Stefansson, K., Tiemeier, H., Uher, R., Völzke, H., Weissman, M. M., Werge, T., Lewis, C. M., Levinson, D. F., Breen, G. & Børglum, A. D., Jul 6 2023, In: American journal of human genetics. 110, 7, p. 1207-1215 9 p.

Research output: Contribution to journal › Article › peer-review

Open Access

7 Scopus citations

The collaborative study on the genetics of alcoholism: Genetics

Johnson, E. C., Salvatore, J. E., Lai, D., Merikangas, A. K., Nurnberger, J. I., Tischfield, J. A., Xuei, X., Kamarajan, C., Wetherill, L., Rice, J. P., Kramer, J. R., Kuperman, S., Foroud, T., Slesinger, P. A., Goate, A. M., Porjesz, B., Dick, D. M., Edenberg, H. J. & Agrawal, A., Oct 2023, In: Genes, Brain and Behavior. 22, 5, e12856.

Research output: Contribution to journal › Review article › peer-review

Open Access

12 Scopus citations

The Collaborative Study on the Genetics of Alcoholism: Overview

COGA Collaborators, Agrawal, A., Brislin, S. J., Bucholz, K. K., Dick, D., Hart, R. P., Johnson, E. C., Meyers, J., Salvatore, J., Slesinger, P., Liu, Y., Plawecki, M. H., Kamarajan, C., Pandey, A., Bierut, L., Rice, J., Schuckit, M., Scott, D., Bauer, L. & Wetherill, L. & 31 others, Xuei, X., Lai, D., O'Connor, S., Chan, G., Chorlian, D. B., Zhang, J., Barr, P., Kinreich, S., Pandey, G., Mullins, N., Anokhin, A., Hartz, S., McCutcheon, V., Saccone, S., Moore, J., Aliev, F., Pang, Z., Kuo, S., Chin, H., Parsian, A., Almasy, L., Foroud, T., Goate, A., Hesselbrock, V., Kramer, J., Kuperman, S., Merikangas, A. K., Nurnberger, J. I., Tischfield, J., Edenberg, H. J. & Porjesz, B., Oct 2023, In: Genes, Brain and Behavior. 22, 5, e12864.

Research output: Contribution to journal › Review article › peer-review

Open Access

8 Scopus citations

The Relationship of Attention-Deficit/Hyperactivity Disorder With Posttraumatic Stress Disorder: A Two-Sample Mendelian Randomization and Population-Based Sibling Comparison Study

Post-Traumatic Stress Disorder Working Group of the Psychiatric Genomics Consortium, Feb 15 2023, In: Biological Psychiatry. 93, 4, p. 362-369 8 p.

Research output: Contribution to journal › Article › peer-review

Open Access

20 Scopus citations

2022

Dissecting the Shared Genetic Architecture of Suicide Attempt, Psychiatric Disorders, and Known Risk Factors

Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium, Bipolar Disorder Working Group of the Psychiatric Genomics Consortium, Eating Disorders Working Group of the Psychiatric Genomics Consortium, German Borderline Genomics Consortium, MVP Suicide Exemplar Workgroup & VA Million Veteran Program, Feb 1 2022, In: Biological Psychiatry. 91, 3, p. 313-327 15 p.

Research output: Contribution to journal › Article › peer-review

Open Access

140 Scopus citations

Enhancing Discovery of Genetic Variants for Posttraumatic Stress Disorder Through Integration of Quantitative Phenotypes and Trauma Exposure Information

Maihofer, A. X., Choi, K. W., Coleman, J. R. I., Daskalakis, N. P., Denckla, C. A., Ketema, E., Morey, R. A., Polimanti, R., Ratanatharathorn, A., Torres, K., Wingo, A. P., Zai, C. C., Aiello, A. E., Almli, L. M., Amstadter, A. B., Andersen, S. B., Andreassen, O. A., Arbisi, P. A., Ashley-Koch, A. E. & Austin, S. B. & 161 others, Avdibegović, E., Borglum, A. D., Babić, D., Bækvad-Hansen, M., Baker, D. G., Beckham, J. C., Bierut, L. J., Bisson, J. I., Boks, M. P., Bolger, E. A., Bradley, B., Brashear, M., Breen, G., Bryant, R. A., Bustamante, A. C., Bybjerg-Grauholm, J., Calabrese, J. R., Caldas-de-Almeida, J. M., Chen, C. Y., Dale, A. M., Dalvie, S., Deckert, J., Delahanty, D. L., Dennis, M. F., Disner, S. G., Domschke, K., Duncan, L. E., Džubur Kulenović, A., Erbes, C. R., Evans, A., Farrer, L. A., Feeny, N. C., Flory, J. D., Forbes, D., Franz, C. E., Galea, S., Garrett, M. E., Gautam, A., Gelaye, B., Gelernter, J., Geuze, E., Gillespie, C. F., Goçi, A., Gordon, S. D., Guffanti, G., Hammamieh, R., Hauser, M. A., Heath, A. C., Hemmings, S. M. J., Hougaard, D. M., Jakovljević, M., Jett, M., Johnson, E. O., Jones, I., Jovanovic, T., Qin, X. J., Karstoft, K. I., Kaufman, M. L., Kessler, R. C., Khan, A., Kimbrel, N. A., King, A. P., Koen, N., Kranzler, H. R., Kremen, W. S., Lawford, B. R., Lebois, L. A. M., Lewis, C., Liberzon, I., Linnstaedt, S. D., Logue, M. W., Lori, A., Lugonja, B., Luykx, J. J., Lyons, M. J., Maples-Keller, J. L., Marmar, C., Martin, N. G., Maurer, D., Mavissakalian, M. R., McFarlane, A., McGlinchey, R. E., McLaughlin, K. A., McLean, S. A., Mehta, D., Mellor, R., Michopoulos, V., Milberg, W., Miller, M. W., Morris, C. P., Mors, O., Mortensen, P. B., Nelson, E. C., Nordentoft, M., Norman, S. B., O'Donnell, M., Orcutt, H. K., Panizzon, M. S., Peters, E. S., Peterson, A. L., Peverill, M., Pietrzak, R. H., Polusny, M. A., Rice, J. P., Risbrough, V. B., Roberts, A. L., Rothbaum, A. O., Rothbaum, B. O., Roy-Byrne, P., Ruggiero, K. J., Rung, A., Rutten, B. P. F., Saccone, N. L., Sanchez, S. E., Schijven, D., Seedat, S., Seligowski, A. V., Seng, J. S., Sheerin, C. M., Silove, D., Smith, A. K., Smoller, J. W., Sponheim, S. R., Stein, D. J., Stevens, J. S., Teicher, M. H., Thompson, W. K., Trapido, E., Uddin, M., Ursano, R. J., van den Heuvel, L. L., Van Hooff, M., Vermetten, E., Vinkers, C. H., Voisey, J., Wang, Y., Wang, Z., Werge, T., Williams, M. A., Williamson, D. E., Winternitz, S., Wolf, C., Wolf, E. J., Yehuda, R., Young, K. A., Young, R. M. D., Zhao, H., Zoellner, L. A., Haas, M., Lasseter, H., Provost, A. C., Salem, R. M., Sebat, J., Shaffer, R. A., Wu, T., Ripke, S., Daly, M. J., Ressler, K. J., Koenen, K. C., Stein, M. B. & Nievergelt, C. M., Apr 1 2022, In: Biological Psychiatry. 91, 7, p. 626-636 11 p.

Research output: Contribution to journal › Article › peer-review

Open Access

28 Scopus citations

Evaluation of Adenosine A2A receptor gene polymorphisms as risk factors of methamphetamine use disorder susceptibility and predictors of craving degree

Wang, H., Ma, Y., Wang, X., Zhang, W., Han, W., Liu, H., Li, M., Xiao, J., Wei, H., Wang, C., Sindhwani, S., Zhang, T., Guan, F. & Rice, J. P., Oct 2022, In: Psychiatry Research. 316, 114790.

Research output: Contribution to journal › Article › peer-review

7 Scopus citations

Genetic diversity fuels gene discovery for tobacco and alcohol use

23andMe Research Team, the BioBank Japan Project, Gu, C. C., Rice, J. P., Saccone, N. L. & Bierut, L. J., Dec 22 2022, In: Nature. 612, 7941, p. 720-724 5 p.

Research output: Contribution to journal › Article › peer-review

Open Access

200 Scopus citations

High Polygenic Risk Scores Are Associated With Early Age of Onset of Alcohol Use Disorder in Adolescents and Young Adults at Risk

Collaborative Study on the Genetics of Alcoholism, Oct 2022, In: Biological Psychiatry Global Open Science. 2, 4, p. 379-388 10 p.

Research output: Contribution to journal › Article › peer-review

Open Access

12 Scopus citations

Identifying the Common Genetic Basis of Antidepressant Response

GSRD Consortium & Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium, Apr 2022, In: Biological Psychiatry Global Open Science. 2, 2, p. 115-126 12 p.

Research output: Contribution to journal › Article › peer-review

Open Access

63 Scopus citations

Parsing genetically influenced risk pathways: genetic loci impact problematic alcohol use via externalizing and specific risk

COGA Collaborators, Dec 2022, In: Translational psychiatry. 12, 1, 420.

Research output: Contribution to journal › Article › peer-review

Open Access

7 Scopus citations

Psychological trauma and the genetic overlap between posttraumatic stress disorder and major depressive disorder

The Million Veteran Program, Post Traumatic Stress Disorder Working Group of the Psychiatric Genomics Consortium, Rice, J. P., Bierut, L. J., Saccone, N. L., Heath, A. C. & Nelson, E. C., Dec 4 2022, In: Psychological medicine. 52, 16, p. 3975-3984 10 p.

Research output: Contribution to journal › Article › peer-review

Open Access

17 Scopus citations

Sex-Dependent Shared and Nonshared Genetic Architecture Across Mood and Psychotic Disorders

Schizophrenia Working Group of the Psychiatric Genomics Consortium, Bipolar Disorder Working Group of the Psychiatric Genomics Consortium, Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium, Sex Differences Cross-Disorder Analysis Group of the Psychiatric Genomics Consortium & iPSYCH, Jan 1 2022, In: Biological Psychiatry. 91, 1, p. 102-117 16 p.

Research output: Contribution to journal › Article › peer-review

Open Access

67 Scopus citations

Uncovering the genetic architecture of broad antisocial behavior through a genome-wide association study meta-analysis

COGA Consortium, Spit for Science Working Group, Agrawal, A., Bierut, L., Rice, J. & Bucholz, K. K., Nov 2022, In: Molecular Psychiatry. 27, 11, p. 4453-4463 11 p.

Research output: Contribution to journal › Article › peer-review

Open Access

32 Scopus citations

2021

A Comparison of Ten Polygenic Score Methods for Psychiatric Disorders Applied Across Multiple Cohorts

Schizophrenia Working Group of the Psychiatric Genomics Consortium & Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium, Nov 1 2021, In: Biological Psychiatry. 90, 9, p. 611-620 10 p.

Research output: Contribution to journal › Article › peer-review

Open Access

119 Scopus citations

Association of polygenic score for major depression with response to lithium in patients with bipolar disorder

Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium, Jun 1 2021, In: Molecular Psychiatry. 26, 6, p. 2457-2470 14 p.

Research output: Contribution to journal › Article › peer-review

54 Scopus citations

Bipolar multiplex families have an increased burden of common risk variants for psychiatric disorders

Bipolar Disorder Working Group of the Psychiatric Genomics Consortium & Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium, Apr 1 2021, In: Molecular Psychiatry. 26, 4, p. 1286-1298 13 p.

Research output: Contribution to journal › Article › peer-review

Open Access

31 Scopus citations

Correction: Genome-wide gene-environment analyses of major depressive disorder and reported lifetime traumatic experiences in UK Biobank (Molecular Psychiatry, (2020), 25, 7, (1430-1446), 10.1038/s41380-019-0546-6)

on the behalf of Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium, Sep 1 2021, In: Molecular Psychiatry. 26, 9, p. 5465 1 p.

Research output: Contribution to journal › Comment/debate

Open Access

1 Scopus citations

Genome-wide association study of more than 40,000 bipolar disorder cases provides new insights into the underlying biology

HUNT All-In Psychiatry, Jun 2021, In: Nature Genetics. 53, 6, p. 817-829 13 p.

Research output: Contribution to journal › Article › peer-review

Open Access

762 Scopus citations

Model-based assessment of replicability for genome-wide association meta-analysis

GWAS and Sequencing Consortium of Alcohol and Nicotine Use (GSCAN), Dec 1 2021, In: Nature communications. 12, 1, 1964.

Research output: Contribution to journal › Article › peer-review

Open Access

21 Scopus citations

Multi-omics integration analysis identifies novel genes for alcoholism with potential overlap with neurodegenerative diseases

The Collaborative Study on the Genetics of Alcoholism (COGA), Dec 1 2021, In: Nature communications. 12, 1, 5071.

Research output: Contribution to journal › Article › peer-review

Open Access

39 Scopus citations

Multivariate analysis of 1.5 million people identifies genetic associations with traits related to self-regulation and addiction

COGA Collaborators, Oct 2021, In: Nature neuroscience. 24, 10, p. 1367-1376 10 p.

Research output: Contribution to journal › Article › peer-review

Open Access

182 Scopus citations

Shared genetic risk between eating disorder- and substance-use-related phenotypes: Evidence from genome-wide association studies

Munn-Chernoff, M. A., Johnson, E. C., Chou, Y. L., Coleman, J. R. I., Thornton, L. M., Walters, R. K., Yilmaz, Z., Baker, J. H., Hübel, C., Gordon, S., Medland, S. E., Watson, H. J., Gaspar, H. A., Bryois, J., Hinney, A., Leppä, V. M., Mattheisen, M., Ripke, S., Yao, S. & Giusti-Rodríguez, P. & 332 others, Hanscombe, K. B., Adan, R. A. H., Alfredsson, L., Ando, T., Andreassen, O. A., Berrettini, W. H., Boehm, I., Boni, C., Boraska Perica, V., Buehren, K., Burghardt, R., Cassina, M., Cichon, S., Clementi, M., Cone, R. D., Courtet, P., Crow, S., Crowley, J. J., Danner, U. N., Davis, O. S. P., de Zwaan, M., Dedoussis, G., Degortes, D., DeSocio, J. E., Dick, D. M., Dikeos, D., Dina, C., Dmitrzak-Weglarz, M., Docampo, E., Duncan, L. E., Egberts, K., Ehrlich, S., Escaramís, G., Esko, T., Estivill, X., Farmer, A., Favaro, A., Fernández-Aranda, F., Fichter, M. M., Fischer, K., Föcker, M., Foretova, L., Forstner, A. J., Forzan, M., Franklin, C. S., Gallinger, S., Giegling, I., Giuranna, J., Gonidakis, F., Gorwood, P., Gratacos Mayora, M., Guillaume, S., Guo, Y., Hakonarson, H., Hatzikotoulas, K., Hauser, J., Hebebrand, J., Helder, S. G., Herms, S., Herpertz-Dahlmann, B., Herzog, W., Huckins, L. M., Hudson, J. I., Imgart, H., Inoko, H., Janout, V., Jiménez-Murcia, S., Julià, A., Kalsi, G., Kaminská, D., Karhunen, L., Karwautz, A., Kas, M. J. H., Kennedy, J. L., Keski-Rahkonen, A., Kiezebrink, K., Kim, Y. R., Klump, K. L., Knudsen, G. P. S., La Via, M. C., Le Hellard, S., Levitan, R. D., Li, D., Lilenfeld, L., Lin, B. D., Lissowska, J., Luykx, J., Magistretti, P. J., Maj, M., Mannik, K., Marsal, S., Marshall, C. R., Mattingsdal, M., McDevitt, S., McGuffin, P., Metspalu, A., Meulenbelt, I., Micali, N., Mitchell, K., Monteleone, A. M., Monteleone, P., Nacmias, B., Navratilova, M., Ntalla, I., O'Toole, J. K., Ophoff, R. A., Padyukov, L., Palotie, A., Pantel, J., Papezova, H., Pinto, D., Rabionet, R., Raevuori, A., Ramoz, N., Reichborn-Kjennerud, T., Ricca, V., Ripatti, S., Ritschel, F., Roberts, M., Rotondo, A., Rujescu, D., Rybakowski, F., Santonastaso, P., Scherag, A., Scherer, S. W., Schmidt, U., Schork, N. J., Schosser, A., Seitz, J., Slachtova, L., Slagboom, P. E., Slof-Op't Landt, M. C. T., Slopien, A., Sorbi, S., Świątkowska, B., Szatkiewicz, J. P., Tachmazidou, I., Tenconi, E., Tortorella, A., Tozzi, F., Treasure, J., Tsitsika, A., Tyszkiewicz-Nwafor, M., Tziouvas, K., van Elburg, A. A., van Furth, E. F., Wagner, G., Walton, E., Widen, E., Zeggini, E., Zerwas, S., Zipfel, S., Bergen, A. W., Boden, J. M., Brandt, H., Crawford, S., Halmi, K. A., Horwood, L. J., Johnson, C., Kaplan, A. S., Kaye, W. H., Mitchell, J., Olsen, C. M., Pearson, J. F., Pedersen, N. L., Strober, M., Werge, T., Whiteman, D. C., Woodside, D. B., Grove, J., Henders, A. K., Larsen, J. T., Parker, R., Petersen, L. V., Jordan, J., Kennedy, M. A., Birgegård, A., Lichtenstein, P., Norring, C., Landén, M., Mortensen, P. B., Polimanti, R., McClintick, J. N., Adkins, A. E., Aliev, F., Bacanu, S. A., Batzler, A., Bertelsen, S., Biernacka, J. M., Bigdeli, T. B., Chen, L. S., Clarke, T. K., Degenhardt, F., Docherty, A. R., Edwards, A. C., Foo, J. C., Fox, L., Frank, J., Hack, L. M., Hartmann, A. M., Hartz, S. M., Heilmann-Heimbach, S., Hodgkinson, C., Hoffmann, P., Hottenga, J. J., Konte, B., Lahti, J., Lahti-Pulkkinen, M., Lai, D., Ligthart, L., Loukola, A., Maher, B. S., Mbarek, H., McIntosh, A. M., McQueen, M. B., Meyers, J. L., Milaneschi, Y., Palviainen, T., Peterson, R. E., Ryu, E., Saccone, N. L., Salvatore, J. E., Sanchez-Roige, S., Schwandt, M., Sherva, R., Streit, F., Strohmaier, J., Thomas, N., Wang, J. C., Webb, B. T., Wedow, R., Wetherill, L., Wills, A. G., Zhou, H., Boardman, J. D., Chen, D., Choi, D. S., Copeland, W. E., Culverhouse, R. C., Dahmen, N., Degenhardt, L., Domingue, B. W., Frye, M. A., Gäebel, W., Hayward, C., Ising, M., Keyes, M., Kiefer, F., Koller, G., Kramer, J., Kuperman, S., Lucae, S., Lynskey, M. T., Maier, W., Mann, K., Männistö, S., Müller-Myhsok, B., Murray, A. D., Nurnberger, J. I., Preuss, U., Räikkönen, K., Reynolds, M. D., Ridinger, M., Scherbaum, N., Schuckit, M. A., Soyka, M., Treutlein, J., Witt, S. H., Wodarz, N., Zill, P., Adkins, D. E., Boomsma, D. I., Bierut, L. J., Brown, S. A., Bucholz, K. K., Costello, E. J., de Wit, H., Diazgranados, N., Eriksson, J. G., Farrer, L. A., Foroud, T. M., Gillespie, N. A., Goate, A. M., Goldman, D., Grucza, R. A., Hancock, D. B., Harris, K. M., Hesselbrock, V., Hewitt, J. K., Hopfer, C. J., Iacono, W. G., Johnson, E. O., Karpyak, V. M., Kendler, K. S., Kranzler, H. R., Krauter, K., Lind, P. A., McGue, M., MacKillop, J., Madden, P. A. F., Maes, H. H., Magnusson, P. K. E., Nelson, E. C., Nöthen, M. M., Palmer, A. A., Penninx, B. W. J. H., Porjesz, B., Rice, J. P., Rietschel, M., Riley, B. P., Rose, R. J., Shen, P. H., Silberg, J., Stallings, M. C., Tarter, R. E., Vanyukov, M. M., Vrieze, S., Wall, T. L., Whitfield, J. B., Zhao, H., Neale, B. M., Wade, T. D., Heath, A. C., Montgomery, G. W., Martin, N. G., Sullivan, P. F., Kaprio, J., Breen, G., Gelernter, J., Edenberg, H. J., Bulik, C. M. & Agrawal, A., Jan 2021, In: Addiction Biology. 26, 1, e12880.

Research output: Contribution to journal › Article › peer-review

Open Access

37 Scopus citations

2020

A large-scale genome-wide association study meta-analysis of cannabis use disorder

Psychiatric Genomics Consortium Substance Use Disorders Workgroup, Dec 1 2020, In: The Lancet Psychiatry. 7, 12, p. 1032-1045 14 p.

Research output: Contribution to journal › Article › peer-review

Open Access

194 Scopus citations

A phenome-wide association and Mendelian Randomisation study of polygenic risk for depression in UK Biobank

Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium, Dec 1 2020, In: Nature communications. 11, 1, 2301.

Research output: Contribution to journal › Article › peer-review

Open Access

79 Scopus citations

Classical Human Leukocyte Antigen Alleles and C4 Haplotypes Are Not Significantly Associated With Depression

Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium, Mar 1 2020, In: Biological Psychiatry. 87, 5, p. 419-430 12 p.

Research output: Contribution to journal › Article › peer-review

Open Access

24 Scopus citations

Genome-wide gene-environment analyses of major depressive disorder and reported lifetime traumatic experiences in UK Biobank

Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium, Jul 1 2020, In: Molecular Psychiatry. 25, 7, p. 1430-1446 17 p.

Research output: Contribution to journal › Article › peer-review

Open Access

111 Scopus citations

Meta-analysis of up to 622,409 individuals identifies 40 novel smoking behaviour associated genetic loci

Understanding Society Scientific Group, EPIC-CVD, GSCAN, Consortium for Genetics of Smoking Behaviour, CHD Exome+ consortium, Oct 1 2020, In: Molecular Psychiatry. 25, 10, p. 2392-2409 18 p.

Research output: Contribution to journal › Article › peer-review

Open Access

84 Scopus citations

Polygenic risk for anxiety influences anxiety comorbidity and suicidal behavior in bipolar disorder

Bipolar Genome Study Consortium (BiGS), Dec 1 2020, In: Translational psychiatry. 10, 1, 298.

Research output: Contribution to journal › Article › peer-review

Open Access

21 Scopus citations

The Genetics of the Mood Disorder Spectrum: Genome-wide Association Analyses of More Than 185,000 Cases and 439,000 Controls

Bipolar Disorder Working Group of the Psychiatric Genomics Consortium & Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium, Jul 15 2020, In: Biological Psychiatry. 88, 2, p. 169-184 16 p.

Research output: Contribution to journal › Article › peer-review

Open Access

137 Scopus citations

2019

Assessment of bidirectional relationships between physical activity and depression among adults a 2-sample Mendelian randomization study

Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium, Apr 2019, In: JAMA psychiatry. 76, 4, p. 399-408 10 p.

Research output: Contribution to journal › Article › peer-review

Open Access

503 Scopus citations

Association of Whole-Genome and NETRIN1 Signaling Pathway–Derived Polygenic Risk Scores for Major Depressive Disorder and White Matter Microstructure in the UK Biobank

Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium & 23andMe Research Team, Jan 2019, In: Biological Psychiatry: Cognitive Neuroscience and Neuroimaging. 4, 1, p. 91-100 10 p.

Research output: Contribution to journal › Article › peer-review

Open Access

19 Scopus citations

Association studies of up to 1.2 million individuals yield new insights into the genetic etiology of tobacco and alcohol use

23andMe Research Team & HUNT All-In Psychiatry, Feb 1 2019, In: Nature Genetics. 51, 2, p. 237-244 8 p.

Research output: Contribution to journal › Letter › peer-review

Open Access

1263 Scopus citations

Efficient region-based test strategy uncovers genetic risk factors for functional outcome in bipolar disorder

Budde, M., Friedrichs, S., Alliey-Rodriguez, N., Ament, S., Badner, J. A., Berrettini, W. H., Bloss, C. S., Byerley, W., Cichon, S., Comes, A. L., Coryell, W., Craig, D. W., Degenhardt, F., Edenberg, H. J., Foroud, T., Forstner, A. J., Frank, J., Gershon, E. S., Goes, F. S. & Greenwood, T. A. & 40 others, Guo, Y., Hipolito, M., Hood, L., Keating, B. J., Koller, D. L., Lawson, W. B., Liu, C., Mahon, P. B., McInnis, M. G., McMahon, F. J., Meier, S. M., Mühleisen, T. W., Murray, S. S., Nievergelt, C. M., Nurnberger, J. I., Nwulia, E. A., Potash, J. B., Quarless, D., Rice, J., Roach, J. C., Scheftner, W. A., Schork, N. J., Shekhtman, T., Shilling, P. D., Smith, E. N., Streit, F., Strohmaier, J., Szelinger, S., Treutlein, J., Witt, S. H., Zandi, P. P., Zhang, P., Zöllner, S., Bickeböller, H., Falkai, P. G., Kelsoe, J. R., Nöthen, M. M., Rietschel, M., Schulze, T. G. & Malzahn, D., Jan 2019, In: European Neuropsychopharmacology. 29, 1, p. 156-170 15 p.

Research output: Contribution to journal › Article › peer-review

Open Access

9 Scopus citations

Exome Chip Meta-analysis Fine Maps Causal Variants and Elucidates the Genetic Architecture of Rare Coding Variants in Smoking and Alcohol Use

CHD Exome+ Consortium & Consortium for Genetics of Smoking Behaviour, Jun 1 2019, In: Biological Psychiatry. 85, 11, p. 946-955 10 p.

Research output: Contribution to journal › Article › peer-review

Open Access

58 Scopus citations

Genome-wide association study identifies 30 loci associated with bipolar disorder

eQTLgen Consortium, BIOS Consortium & the Bipolar Disorder Working Group of the Psychiatric Genomics Consortium, May 1 2019, In: Nature Genetics. 51, 5, p. 793-803 11 p.

Research output: Contribution to journal › Article › peer-review

Open Access

1016 Scopus citations

Genome-wide Burden of Rare Short Deletions Is Enriched in Major Depressive Disorder in Four Cohorts

Zhang, X., Abdellaoui, A., Rucker, J., de Jong, S., Potash, J. B., Weissman, M. M., Shi, J., Knowles, J. A., Pato, C., Pato, M., Sobell, J., Smit, J. H., Hottenga, J. J., de Geus, E. J. C., Lewis, C. M., Buttenschøn, H. N., Craddock, N., Jones, I., Jones, L. & McGuffin, P. & 13 others, Mors, O., Owen, M. J., Preisig, M., Rietschel, M., Rice, J. P., Rivera, M., Uher, R., Gejman, P. V., Sanders, A. R., Boomsma, D., Penninx, B. W. J. H., Breen, G. & Levinson, D. F., Jun 15 2019, In: Biological Psychiatry. 85, 12, p. 1065-1073 9 p.

Research output: Contribution to journal › Article › peer-review

Open Access

24 Scopus citations

Identification of common genetic risk variants for autism spectrum disorder

Autism Spectrum Disorder Working Group of the Psychiatric Genomics Consortium, BUPGEN, Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium & 23andMe Research Team, Mar 1 2019, In: Nature Genetics. 51, 3, p. 431-444 14 p.

Research output: Contribution to journal › Article › peer-review

Open Access

1437 Scopus citations

John Rice

Research output

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