John Rice

Professor of Mathematics in Psychiatry, Professor of Biostatistics, Professor of Genetics

    • 46329 Citations
    1978 …2020

    Research output per year

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    Personal profile

    Research interests

    Dr. Rice's current research interests include methods development in genetic epidemiology and family study techniques, and the collection and analysis of genome-wide association data on the affective disorders, schizophrenia, smoking and alcoholism. Dr. Rice is the PI in St. Louis for the Collaborative Depression Study (CDS) a five-site study which began in 1978 to collectively follow 955 probands with affective disorders and to assess 612 of their families, and is PI on a multi-site case-control study of Bipolar Disorder and a co-investigator on studies of schizophrenia, alcohol dependence and nicotine dependence. Another area of expertise is in the management and analysis of data from genetic repositories. Dr. Rice maintains the genetic database for the NIMH and NIDA Centers for Genetic Studies. The NIMH repository has existing genetic data on Bipolar Disorder, Schizophrenia, Autism, Major Depression and Alzheimer disease, and these existing datasets are housed in St. Louis.

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    Research Output

    A phenome-wide association and Mendelian Randomisation study of polygenic risk for depression in UK Biobank

    Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium, Dec 1 2020, In : Nature communications. 11, 1, 2301.

    Research output: Contribution to journalArticle

    Open Access
  • Association of polygenic score for major depression with response to lithium in patients with bipolar disorder

    Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium, 2020, (Accepted/In press) In : Molecular Psychiatry.

    Research output: Contribution to journalArticle

  • 1 Scopus citations

    Classical Human Leukocyte Antigen Alleles and C4 Haplotypes Are Not Significantly Associated With Depression

    Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium, Mar 1 2020, In : Biological Psychiatry. 87, 5, p. 419-430 12 p.

    Research output: Contribution to journalArticle

    Open Access
  • 2 Scopus citations

    Correction: Genome-wide gene-environment analyses of major depressive disorder and reported lifetime traumatic experiences in UK Biobank (Molecular Psychiatry, (2020), 10.1038/s41380-019-0546-6)

    on the behalf of Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium, 2020, (Accepted/In press) In : Molecular Psychiatry.

    Research output: Contribution to journalComment/debate

    Open Access
  • Genome-wide gene-environment analyses of major depressive disorder and reported lifetime traumatic experiences in UK Biobank

    Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium, Jul 1 2020, In : Molecular Psychiatry. 25, 7, p. 1430-1446 17 p.

    Research output: Contribution to journalArticle

  • 7 Scopus citations