John Morris

Research output

Research output per year 1984 2005 2006 2010 2011 2013 2015 2016 2017 2018 2019 2020 2021 2022 2023 2023

• 871 Article
• 60 Review article
• 30 Letter
• 29 Comment/debate
• 39 More
  • 23 Editorial
  • 10 Chapter
  • 3 Short survey
  • 1 Book
  • 1 Conference contribution
  • 1 Foreword/postscript

Research output per year

Research output per year

Search results

• 2023

  A data-driven examination of apathy and depressive symptoms in dementia with independent replication

  for the Alzheimer's Disease Neuroimaging Initiative, Jan 1 2023, In: Alzheimer's and Dementia: Diagnosis, Assessment and Disease Monitoring. 15, 1, e12398.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Apathy 100%
  • Dementia 65%
  • Depression 51%
  • Latent Class Analysis 14%
  • Clinical Studies 9%
  1 Scopus citations

• A flexible modeling approach for biomarker-based computation of absolute risk of Alzheimer's disease dementia

  Hartz, S. M., Mozersky, J., Schindler, S., Linnenbringer, E., Wang, J., Gordon, B., Raji, C. A., Moulder, K. L., West, T., Benzinger, T. L. S., Cruchaga, C., Hassenstab, J. J., Bierut, L. J., Xiong, C. & Morris, J., Apr 2023, In: Alzheimer's and Dementia. 19, 4, p. 1452-1465 14 p.

  Research output: Contribution to journal › Article › peer-review

  • dementia 100%
  • Alzheimer Disease 77%
  • Biomarkers 64%
  • Area Under Curve 40%
  • Demography 19%
  1 Scopus citations

• Alzheimer’s disease genetic risk and cognitive reserve in relationship to long-term cognitive trajectories among cognitively normal individuals

  Pettigrew, C., Nazarovs, J., Soldan, A., Singh, V., Wang, J., Hohman, T., Dumitrescu, L., Libby, J., Kunkle, B., Gross, A. L., Johnson, S., Lu, Q., Engelman, C., Masters, C. L., Maruff, P., Laws, S. M., Morris, J. C., Hassenstab, J., Cruchaga, C., Resnick, S. M., & 3 othersKitner-Triolo, M. H., An, Y. & Albert, M., Dec 2023, In: Alzheimer's Research and Therapy. 15, 1, 66.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Cognitive Reserve 100%
  • Apolipoprotein E4 74%
  • Alzheimer Disease 52%
  • Cognition 32%
  • Executive Function 28%
  2 Scopus citations

• A practitioner's guide to geospatial analysis in a neuroimaging context

  Wisch, J. K., Babulal, G. M., Petersen, K., Millar, P. R., Shacham, E., Scroggins, S., Boerwinkle, A. H., Flores, S., Keefe, S., Gordon, B., Morris, J. & Ances, B. M., Jan 1 2023, In: Alzheimer's and Dementia: Diagnosis, Assessment and Disease Monitoring. 15, 1, e12413.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Neuroimaging 100%
  • Brain 54%
  • Geographic Mapping 27%
  • Health 17%
  • Sample Size 16%
  1 Scopus citations

• Association Between Socioeconomic Factors, Race, and Use of a Specialty Memory Clinic

  Lewis, A., Gupta, A., Oh, I., Schindler, S. E., Ghoshal, N., Abrams, Z., Foraker, R., Snider, B. J., Morris, J. C., Balls-Berry, J., Gupta, M., Payne, P. R. O. & Lai, A. M., Oct 3 2023, In: Neurology. 101, 14, p. E1424-E1433

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Memory 100%
  • African Continental Ancestry Group 44%
  • Dementia 28%
  • Social Class 21%
  • Alzheimer Disease 17%
  1 Scopus citations

• Association of Stages of Objective Memory Impairment With Incident Symptomatic Cognitive Impairment in Cognitively Normal Individuals

  Grober, E., Petersen, K. K., Lipton, R. B., Hassenstab, J., Morris, J. C., Gordon, B. A. & Ezzati, A., May 30 2023, In: Neurology. 100, 22, p. E2279-E2289

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Cognitive Dysfunction 100%
  • Memory 88%
  • Mental Status and Dementia Tests 29%
  • Biomarkers 27%
  • Amyloid 13%

• Associations between neuropsychiatric symptoms of affective and vegetative domains and brain morphology in aging people with mild cognitive impairment and Alzheimer's disease

  for the ADNI, Jun 2023, In: International Journal of Geriatric Psychiatry. 38, 6, e5952.

  Research output: Contribution to journal › Article › peer-review

  • Affective Symptoms 100%
  • Cognitive Dysfunction 68%
  • Alzheimer Disease 64%
  • Brain 40%
  • Apathy 21%

• Associations of Stages of Objective Memory Impairment with Cerebrospinal Fluid and Neuroimaging Biomarkers of Alzheimer’s Disease

  Petersen, K. K., Ezzati, A., Lipton, R. B., Gordon, B., Hassenstab, J., Morris, J. & Grober, E., Jan 2023, In: The journal of prevention of Alzheimer's disease. 10, 1, p. 112-119 8 p.

  Research output: Contribution to journal › Article › peer-review

  • Neuroimaging 100%
  • Cerebrospinal Fluid 95%
  • Alzheimer Disease 85%
  • Memory 80%
  • Biomarkers 71%

• Author Correction: Predicting Alzheimer’s disease progression using multi-modal deep learning approach (Scientific Reports, (2019), 9, 1, (1952), 10.1038/s41598-018-37769-z)

  Lee, G., Nho, K., Kang, B., Sohn, K. A., Kim, D., Weiner, M. W., Aisen, P., Petersen, R., Jack, C. R., Jagust, W., Trojanowki, J. Q., Toga, A. W., Beckett, L., Green, R. C., Saykin, A. J., Morris, J., Shaw, L. M., Khachaturian, Z., Sorensen, G., Carrillo, M., & 294 othersKuller, L., Raichle, M., Paul, S., Davies, P., Fillit, H., Hefti, F., Holtzman, D., Mesulam, M. M., Potter, W., Snyder, P., Montine, T., Thomas, R. G., Donohue, M., Walter, S., Sather, T., Jiminez, G., Balasubramanian, A. B., Mason, J., Sim, I., Harvey, D., Bernstein, M., Fox, N., Thompson, P., Schuff, N., DeCArli, C., Borowski, B., Gunter, J., Senjem, M., Vemuri, P., Jones, D., Kantarci, K., Ward, C., Koeppe, R. A., Foster, N., Reiman, E. M., Chen, K., Mathis, C., Landau, S., Cairns, N. J., Householder, E., Taylor-Reinwald, L., Lee, V., Korecka, M., Figurski, M., Crawford, K., Neu, S., Foroud, T. M., Potkin, S., Shen, L., Faber, K., Kim, S., Tha, L., Frank, R., Hsiao, J., Kaye, J., Quinn, J., Silbert, L., Lind, B., Carter, R., Dolen, S., Ances, B., Carroll, M., Creech, M. L., Franklin, E., Mintun, M. A., Schneider, S., Oliver, A., Schneider, L. S., Pawluczyk, S., Beccera, M., Teodoro, L., Spann, B. M., Brewer, J., Vanderswag, H., Fleisher, A., Marson, D., Griffith, R., Clark, D., Geldmacher, D., Brockington, J., Roberson, E., Love, M. N., Heidebrink, J. L., Lord, J. L., Mason, S. S., Albers, C. S., Knopman, D., Johnson, K., Grossman, H., Mitsis, E., Shah, R. C., deToledo-Morrell, L., Doody, R. S., Villanueva-Meyer, J., Chowdhury, M., Rountree, S., Dang, M., Duara, R., Varon, D., Greig, M. T., Roberts, P., Stern, Y., Honig, L. S., Bell, K. L., Albert, M., Onyike, C., D’Agostino, D., Kielb, S., Galvin, J. E., Cerbone, B., Michel, C. A., Pogorelec, D. M., Rusinek, H., de Leon, M. J., Glodzik, L., De Santi, S., Womack, K., Womack, K., Quiceno, M., Doraiswamy, P. M., Petrella, J. R., Borges-Neto, S., Wong, T. Z., Coleman, E., Levey, A. I., Lah, J. J., Cella, J. S., Burns, J. M., Swerdlow, R. H., Brooks, W. M., Arnold, S. E., Karlawish, J. H., Wolk, D., Clark, C. M., Apostolova, L., Tingus, K., Woo, E., Silverman, D. H. S., Lu, P. H., Bartzokis, G., Smith, C. D., Jicha, G., Hardy, P., Sinha, P., Oates, E., Conrad, G., Graff-Radford, N. R., Parfitt, F., Kendall, T., Johnson, H., Lopez, O. L., Oakley, M. A., Simpson, D. M., Farlow, M. R., Hake, A. M., Matthews, B. R., Brosch, J. R., Herring, S., Hunt, C., Porsteinsson, A. P., Goldstein, B. S., Martin, K., Makino, K. M., Ismail, M. S., Brand, C., Mulnard, R. A., Thai, G., Mc-Adams-Ortiz, C., van Dyck, C. H., Carson, R. E., MacAvoy, M. G., Varma, P., Chertkow, H., Bergman, H., Hosein, C., Black, S., Stefanovic, B., Caldwell, C., Hsiung, G. Y. R., Feldman, H., Mudge, B., Assaly, M., Finger, E., Pasternack, S., Rachisky, I., Trost, D., Kertesz, A., Bernick, C., Munic, D., Lipowski, K., Weintraub, M., Bonakdarpour, B., Kerwin, D., Wu, C. K., Johnson, N., Sadowsky, C., Villena, T., Turner, R. S., Johnson, K., Reynolds, B., Sperling, R. A., Johnson, K. A., Marshall, G., Yesavage, J., Taylor, J. L., Lane, B., Rosen, A., Tinklenberg, J., Sabbagh, M. N., Belden, C. M., Jacobson, S. A., Sirrel, S. A., Kowall, N., Killiany, R., Budson, A. E., Norbash, A., Johnson, P. L., Obisesan, T. O., Wolday, S., Allard, J., Lerner, A., Ogrocki, P., Tatsuoka, C., Fatica, P., Fletcher, E., Maillard, P., Olichney, J., Carmichael, O., Kittur, S., Borrie, M., Lee, T. Y., Bartha, R., Johnson, S., Asthana, S., Carlsson, C. M., Preda, A., Nguyen, D., Tariot, P., Burke, A., Trncic, N., Fleisher, A., Reeder, S., Bates, V., Capote, H., Rainka, M., Scharre, D. W., Kataki, M., Adeli, A., Zimmerman, E. A., Celmins, D., Brown, A. D., Pearlson, G. D., Blank, K., Anderson, K., Flashman, L. A., Seltzer, M., Hynes, M. L., Santulli, R. B., Sink, K. M., Gordineer, L., Williamson, J. D., Garg, P., Watkins, F., Ott, B. R., Querfurth, H., Tremont, G., Salloway, S., Malloy, P., Correia, S., Rosen, H. J., Miller, B. L., Perry, D., Mintzer, J., Spicer, K., Bachman, D., Finger, E., Pasternak, S., Rachinsky, I., Rogers, J., Drost, D., Pomara, N., Hernando, R., Sarrael, A., Schultz, S. K., Ponto, L. L. B., Shim, H., Smith, K. E., Relkin, N., Chaing, G., Lin, M., Ravdin, L., Smith, A., Raj, B. A. & Fargher, K., Dec 2023, In: Scientific reports. 13, 1, 12466.

  Research output: Contribution to journal › Comment/debate

  Open Access

  • Deep Learning 100%
  • Disease Progression 58%
  • Alzheimer Disease 56%

• Biomarker clustering in autosomal dominant Alzheimer's disease

  for the Dominantly Inherited Alzheimer Network (DIAN), Jan 2023, In: Alzheimer's and Dementia. 19, 1, p. 274-284 11 p.

  Research output: Contribution to journal › Article › peer-review

  • dementia 100%
  • Cluster Analysis 88%
  • integrity 85%
  • Alzheimer Disease 77%
  • Biomarkers 64%
  1 Scopus citations

• Brain aerobic glycolysis and resilience in Alzheimer disease

  Goyal, M. S., Blazey, T., Metcalf, N. V., McAvoy, M. P., Strain, J. F., Rahmani, M., Durbin, T. J., Xiong, C., Benzinger, T. L. S., Morris, J. C., Raichle, M. E. & Vlassenko, A. G., Feb 14 2023, In: Proceedings of the National Academy of Sciences of the United States of America. 120, 7, e2212256120.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Glycolysis 100%
  • Alzheimer Disease 73%
  • Amyloid 51%
  • Brain 46%
  • Oxygen Consumption 26%
  5 Scopus citations

• Brain network decoupling with increased serum neurofilament and reduced cognitive function in Alzheimer’s disease

  Dominantly Inherited Alzheimer Network, Jul 1 2023, In: Brain. 146, 7, p. 2928-2943 16 p.

  Research output: Contribution to journal › Article › peer-review

  • Intermediate Filaments 100%
  • Cognition 71%
  • Alzheimer Disease 70%
  • Brain 44%
  • Serum 41%
  1 Scopus citations

• Cerebrospinal fluid proteomics define the natural history of autosomal dominant Alzheimer’s disease

  the Dominantly Inherited Alzheimer Network, Aug 2023, In: Nature medicine. 29, 8, p. 1979-1988 10 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Proteomics 100%
  • Cerebrospinal Fluid 94%
  • Alzheimer Disease 84%
  • Protein 44%
  • Proteins 40%
  1 Scopus citations

• Change in Cerebrospinal Fluid Tau Microtubule Binding Region Detects Symptom Onset, Cognitive Decline, Tangles, and Atrophy in Dominantly Inherited Alzheimer's Disease

  and the Dominantly Inherited Alzheimer Network, Horie, K., Li, Y., Barthelemy, N., Gordon, B., Hassenstab, J., Benzinger, T., Niven, A., Morris, J., Karch, C. M., Xiong, C., Allegri, R., Mendez, P. C., Ikeuchi, T., Kasuga, K., Noble, J., Farlow, M., Chhatwal, J., Day, G., Schofield, P. R., & 11 othersMasters, C. L., Levin, J., Jucker, M., Lee, J. H., Roh, J. H., Sato, C., Sachdev, P., Koyama, A., Reyderman, L., Bateman, R. J. & McDade, E., Jun 2023, In: Annals of neurology. 93, 6, p. 1158-1172 15 p.

  Research output: Contribution to journal › Article › peer-review

  • Microtubules 100%
  • Cerebrospinal Fluid 89%
  • Atrophy 89%
  • Cognitive Dysfunction 84%
  • Alzheimer Disease 79%
  1 Scopus citations

• Circular-SWAT for deep learning based diagnostic classification of Alzheimer's disease: application to metabolome data

  Alzheimer's Disease Metabolomics Consortium (ADMC) & Alzheimer’s Disease Neuroimaging Initiative (ADNI), Nov 2023, In: EBioMedicine. 97, 104820.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Deep Learning 100%
  • Metabolome 82%
  • Alzheimer Disease 56%
  • Lipid 50%
  • Application 22%

• Comparing Tau PET Visual Interpretation with Tau PET Quantification, Cerebrospinal Fluid Biomarkers, and Longitudinal Clinical Assessment

  Chen, C. D., Ponisio, M. R., Lang, J. A., Flores, S., Schindler, S. E., Fagan, A. M., Morris, J. C. & Benzinger, T. L. S., 2023, In: Journal of Alzheimer's Disease. 93, 2, p. 765-777 13 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • 7-(6-fluoropyridin-3-yl)-5H-pyrido(4,3-b)indole 100%
  • quantification 63%
  • dementia 56%
  • Cerebrospinal Fluid 49%
  • Biomarkers 36%
  1 Scopus citations

• Cortical atrophy and leukoaraiosis, imaging markers of cerebrovascular small vessel disease, are associated with driving behavior changes among cognitively normal older adults

  Babulal, G. M., Chen, L., Carr, D. B., Johnson, A. M., Shimony, J. S., Doherty, J., Murphy, S., Walker, A., Domash, H., Hornbeck, R., Keefe, S., Flores, S., Raji, C. A., Morris, J. C., Ances, B. M. & Benzinger, T. L. S., May 15 2023, In: Journal of the Neurological Sciences. 448, 120616.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Leukoaraiosis 100%
  • Cerebral Small Vessel Diseases 95%
  • Atrophy 56%
  • Magnetic Resonance Imaging 17%
  • Population Growth 16%
  1 Scopus citations

• Cross-sectional and longitudinal comparisons of biomarkers and cognition among asymptomatic middle-aged individuals with a parental history of either autosomal dominant or late-onset Alzheimer's disease

  and Dominantly Inherited Alzheimer Network (DIAN), Xiong, C., McCue, L. M., Buckles, V., Grant, E., Agboola, F., Coble, D., Bateman, R. J., Fagan, A. M., Benzinger, T. L. S., Hassenstab, J., Schindler, S. E., McDade, E., Moulder, K., Gordon, B. A., Cruchaga, C., Day, G. S., Ikeuchi, T., Suzuki, K., Allegri, R. F., & 3 othersVöglein, J., Levin, J. & Morris, J. C., Jul 2023, In: Alzheimer's and Dementia. 19, 7, p. 2923-2932 10 p.

  Research output: Contribution to journal › Article › peer-review

  • 2-(4'-(methylamino)phenyl)-6-hydroxybenzothiazole 100%
  • dementia 86%
  • cognition 69%
  • Cognition 67%
  • Alzheimer Disease 66%

• CSF MTBR-tau243 is a specific biomarker of tau tangle pathology in Alzheimer’s disease

  Horie, K., Salvadó, G., Barthélemy, N. R., Janelidze, S., Li, Y., He, Y., Saef, B., Chen, C. D., Jiang, H., Strandberg, O., Pichet Binette, A., Palmqvist, S., Sato, C., Sachdev, P., Koyama, A., Gordon, B. A., Benzinger, T. L. S., Holtzman, D. M., Morris, J. C., Mattsson-Carlgren, N., & 5 othersStomrud, E., Ossenkoppele, R., Schindler, S. E., Hansson, O. & Bateman, R. J., Aug 2023, In: Nature medicine. 29, 8, p. 1954-1963 10 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Microtubules 100%
  • Biological Marker 92%
  • Cerebrospinal Fluid 89%
  • Alzheimer Disease 79%
  • Biomarkers 66%
  6 Scopus citations

• CSF tau phosphorylation occupancies at T217 and T205 represent improved biomarkers of amyloid and tau pathology in Alzheimer’s disease

  Barthélemy, N. R., Saef, B., Li, Y., Gordon, B. A., He, Y., Horie, K., Stomrud, E., Salvadó, G., Janelidze, S., Sato, C., Ovod, V., Henson, R. L., Fagan, A. M., Benzinger, T. L. S., Xiong, C., Morris, J. C., Hansson, O., Bateman, R. J. & Schindler, S. E., Apr 2023, In: Nature Aging. 3, 4, p. 391-401 11 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Amyloid 100%
  • Cerebrospinal Fluid 91%
  • Alzheimer Disease 81%
  • Phosphorylation 72%
  • Biomarkers 68%
  5 Scopus citations

• Differential impacts of road diets on driving behavior among older adults with and without preclinical Alzheimer's pathology

  Wisch, J. K., Kianfar, J., Carr, D. B., Dickerson, A. D., Vivoda, J., Harmon, A., Trani, J. F., Johnson, A. M., Doherty, J. M., Murphy, S. A., Domash, H., Ashraf, S., Aschenbrenner, A. J., Schindler, S. E., Benzinger, T. L. S., Morris, J. C., Ances, B. M. & Babulal, G. M., Oct 2023, In: Transportation Research Part F: Traffic Psychology and Behaviour. 98, p. 18-28 11 p.

  Research output: Contribution to journal › Article › peer-review

  • Alzheimer's Disease 100%
  • traffic behavior 90%
  • Nutrition 87%
  • Pathology 78%
  • Diet 67%

• Effect of exercise engagement and cardiovascular risk on neuronal injury

  Stojanovic, M., Schindler, S. E., Morris, J. C. & Head, D., Oct 2023, In: Alzheimer's and Dementia. 19, 10, p. 4454-4462 9 p.

  Research output: Contribution to journal › Article › peer-review

  • Wounds and Injuries 100%
  • moderator 56%
  • Neurocalcin 52%
  • Neurogranin 50%
  • Synaptosomal-Associated Protein 25 46%

• Erratum: Comparative Analysis of Alzheimer's Disease Cerebrospinal Fluid Biomarkers Measurement by Multiplex SOMAscan Platform and Immunoassay-Based Approach (Journal of Alzheimer's Disease (2022) 89 (193–207) DOI: 10.3233/JAD-220399)

  Timsina, J., Gomez-Fonseca, D., Wang, L., Do, A., Western, D., Alvarez, I., Aguilar, M., Pastor, P., Henson, R. L., Herries, E., Xiong, C., Schindler, S., Fagan, A. M., Bateman, R. J., Farlow, M., Morris, J., Perrin, R. J., Moulder, K., Hassenstab, J., Voglein, J., & 4 othersChhatwal, J., Mori, H., Ju Sung, Y. & Cruchaga, C., 2023, In: Journal of Alzheimer's Disease. 91, 2, p. 911 1 p.

  Research output: Contribution to journal › Comment/debate

  Open Access

  • dementia 100%
  • Immunoassay 99%
  • Cerebrospinal Fluid 86%
  • Alzheimer Disease 77%
  • Morus 72%

• Evaluation of the Electronic Clinical Dementia Rating for Dementia Screening

  Nosheny, R. L., Yen, D., Howell, T., Camacho, M., Moulder, K., Gummadi, S., Bui, C., Kannan, S., Ashford, M. T., Knight, K., Mayo, C., McMillan, M., Petersen, R. C., Stricker, N. H., Roberson, E. D., Chambless, C., Gersteneker, A., Martin, R., Kennedy, R., Zhang, Y., & 8 othersKukull, W., Flenniken, D., Fockler, J., Truran, D., Mackin, R. S., Weiner, M. W., Morris, J. C. & Li, Y., Sep 14 2023, In: JAMA Network Open. 6, 9, p. E2333786

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Mental Status and Dementia Tests 100%
  • Dementia 80%
  • Cognitive Dysfunction 9%
  • Alzheimer disease, familial, type 3 9%
  • Alzheimer Disease 9%

• Everyday Driving and Plasma Biomarkers in Alzheimer's Disease: Leveraging Artificial Intelligence to Expand Our Diagnostic Toolkit

  Bayat, S., Roe, C. M., Schindler, S., Murphy, S. A., Doherty, J. M., Johnson, A. M., Walker, A., Ances, B. M., Morris, J. C. & Babulal, G. M., 2023, In: Journal of Alzheimer's Disease. 92, 4, p. 1487-1497 11 p.

  Research output: Contribution to journal › Article › peer-review

  • Artificial Intelligence 100%
  • dementia 75%
  • artificial intelligence 75%
  • diagnostic 63%
  • traffic behavior 59%

• First presentation with neuropsychiatric symptoms in autosomal dominant Alzheimer's disease: The Dominantly Inherited Alzheimer's Network Study

  O'Connor, A., Rice, H., Barnes, J., Ryan, N. S., Liu, K. Y., Allegri, R. F., Berman, S., Ringman, J. M., Cruchaga, C., Farlow, M. R., Hassenstab, J., Lee, J. H., Perrin, R. J., Xiong, C., Gordon, B., Levey, A. I., Goate, A., Graff-Radford, N., Levin, J., Jucker, M., & 13 othersBenzinger, T., McDade, E., Mori, H., Noble, J. M., Schofield, P. R., Martins, R. N., Salloway, S., Chhatwal, J., Morris, J. C., Bateman, R., Howard, R., Reeves, S. & Fox, N. C., May 1 2023, In: Journal of Neurology, Neurosurgery and Psychiatry. 94, 5, p. 403-405 3 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

• Gut microbiome composition may be an indicator of preclinical Alzheimer’s disease

  Ferreiro, A. L., Choi, J. H., Ryou, J., Newcomer, E. P., Thompson, R., Bollinger, R. M., Hall-Moore, C., Ndao, I. M., Sax, L., Benzinger, T. L. S., Stark, S. L., Holtzman, D. M., Fagan, A. M., Schindler, S. E., Cruchaga, C., Butt, O. H., Morris, J. C., Tarr, P. I., Ances, B. M. & Dantas, G., 2023, In: Science translational medicine. 15, 700, eabo2984.

  Research output: Contribution to journal › Article › peer-review

  • Gastrointestinal Microbiome 100%
  • Alzheimer Disease 78%
  • Biomarkers 16%
  • Machine Learning 9%
  • Neuropathology 9%
  7 Scopus citations

• Higher systolic blood pressure in early-mid adulthood is associated with poorer cognitive performance in those with a dominantly inherited Alzheimer's disease mutation but not in non-carriers. Results from the DIAN study

  Dominantly Inherited Alzheimer Network (DIAN), Xu, Y., Aung, H. L., Bateman, R. J., Brooks, W. S., Chhatwal, J., Day, G., Fagan, A. M., Farlow, M. R., Gordon, B., Kehoe, P. G., Levin, J., Mori, H., Morris, J., Wharton, W., Humburg, P., Schofield, P. R. & Peters, R., 2023, (Accepted/In press) In: Alzheimer's and Dementia.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • blood pressure 100%
  • dementia 79%
  • adulthood 67%
  • cognition 64%
  • Alzheimer Disease 61%

• Human striatal glia differentially contribute to AD- and PD-specific neurodegeneration

  Xu, J., Farsad, H. L., Hou, Y., Barclay, K., Lopez, B. A., Yamada, S., Saliu, I. O., Shi, Y., Knight, W. C., Bateman, R. J., Benzinger, T. L. S., Yi, J. J., Li, Q., Wang, T., Perlmutter, J. S., Morris, J. C. & Zhao, G., Mar 2023, In: Nature Aging. 3, 3, p. 346-365 20 p.

  Research output: Contribution to journal › Article › peer-review

  • Microglia 100%
  • Corpus Striatum 95%
  • Neuroglia 87%
  • Parkinson Disease 82%
  • Alzheimer Disease 76%
  5 Scopus citations

• Improving Early Recognition of Treatment-Responsive Causes of Rapidly Progressive Dementia: The STAM₃P Score

  Satyadev, N., Tipton, P. W., Martens, Y., Dunham, S. R., Geschwind, M. D., Morris, J., Brier, M. R., Graff-Radford, N. R. & Day, G., 2023, (Accepted/In press) In: Annals of neurology.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Dementia 100%
  • Age of Onset 22%
  • Therapeutics 19%
  • Hashimoto's encephalitis 17%
  • Leukocytosis 13%
  1 Scopus citations

• Increased Cognitive Effort Costs in Healthy Aging and Preclinical Alzheimer’s Disease

  Aschenbrenner, A. J., Crawford, J. L., Peelle, J. E., Fagan, A. M., Benzinger, T. L. S., Morris, J. C., Hassenstab, J. & Braver, T. S., 2023, (Accepted/In press) In: Psychology and Aging.

  Research output: Contribution to journal › Article › peer-review

  • Healthy Aging 100%
  • dementia 80%
  • Alzheimer Disease 62%
  • Costs and Cost Analysis 49%
  • Amyloid 45%
  1 Scopus citations

• Increasing participant diversity in AD research: Plans for digital screening, blood testing, and a community-engaged approach in the Alzheimer's Disease Neuroimaging Initiative 4

  Alzheimer’s Disease Neuroimaging Initiative, Jan 2023, In: Alzheimer's and Dementia. 19, 1, p. 307-317 11 p.

  Research output: Contribution to journal › Review article › peer-review

  Open Access

  • dementia 100%
  • Neuroimaging 90%
  • Alzheimer Disease 77%
  • Biomarkers 64%
  • Clinical Trials 41%
  14 Scopus citations

• Investigating Tau and Amyloid Tracer Skull Binding in Studies of Alzheimer Disease

  Flores, S., Chen, C. D., Su, Y., Dincer, A., Keefe, S. J., McKay, N. S., Paulick, A. M., Perez-Carrillo, G. G., Wang, L., Hornbeck, R. C., Goyal, M., Vlassenko, A., Schwarz, S., Nickels, M. L., Wong, D. F., Tu, Z., McConathy, J. E., Morris, J. C., Benzinger, T. L. S. & Gordon, B. A., Feb 1 2023, In: Journal of Nuclear Medicine. 64, 2

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Skull 100%
  • Amyloid 96%
  • 7-(6-fluoropyridin-3-yl)-5H-pyrido(4,3-b)indole 89%
  • Alzheimer Disease 78%
  • Hyperostosis 14%
  5 Scopus citations

• Investigation of sex differences in mutation carriers of the Dominantly Inherited Alzheimer Network

  Wagemann, O., Li, Y., Hassenstab, J., Aschenbrenner, A. J., McKay, N. S., Gordon, B. A., Benzinger, T. L. S., Xiong, C., Cruchaga, C., Renton, A. E., Perrin, R. J., Berman, S. B., Chhatwal, J. P., Farlow, M. R., Day, G., Ikeuchi, T., Jucker, M., Lopera, F., Mori, H., Noble, J. M., & 8 othersSánchez-Valle, R., Schofield, P. R., Morris, J. C., Daniels, A., Levin, J., Bateman, R. J., McDade, E. & Llibre-Guerra, J. J., 2023, (Accepted/In press) In: Alzheimer's and Dementia.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • dementia 100%
  • Sex Characteristics 93%
  • Mutation 55%
  • cognition 53%
  • Alzheimer Disease 38%

• In vivo cortical diffusion imaging relates to Alzheimer’s disease neuropathology

  Torso, M., Ridgway, G. R., Valotti, M., Hardingham, I., Chance, S. A., Brewer, J., Lopez, O., Hyman, B., Grabowski, T., Sano, M., Chui, H., Albert, M., Morris, J., Kaye, J., Wisniewski, T., Small, S., Trojanowski, J., DeCarli, C., Saykin, A., Bennett, D., & 23 othersRosenberg, R., Kowall, N., Vassar, R., LaFerla, F., Petersen, R., Reiman, E., Miller, B., Levey, A., Van Eldik, L., Asthana, S., Swerdlow, R., Golde, T., Strittmatter, S., Henderson, V., Craft, S., Paulson, H., Seshadri, S., Roberson, E., Sabbagh, M., Rosenberg, G., Jefferson, A., Whitson, H. & Leverenz, J., Dec 2023, In: Alzheimer's Research and Therapy. 15, 1, 165.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Neuropathology 100%
  • Locus Coeruleus 89%
  • Hypopigmentation 82%
  • Alzheimer Disease 69%
  • Diffusion Magnetic Resonance Imaging 52%

• Large multi-ethnic genetic analyses of amyloid imaging identify new genes for Alzheimer disease

  Knight Alzheimer Disease Research Center (Knight ADRC), the Dominantly Inherited Alzheimer Network (DIAN), Alzheimer’s Disease Neuroimaging Initiative (ADNI), ADNI-DOD, A4 Study Team, the Australian Imaging Biomarkers, Lifestyle (AIBL) Study, Ali, M., Archer, D. B., Gorijala, P., Western, D., Timsina, J., Fernández, M. V., Chen, G., Gordon, B., Benzinger, T. L. S., Xiong, C., Morris, J. C., Bateman, R. J., Karch, C. M., McDade, E., Sung, Y. J., & 1 othersCruchaga, C., Dec 2023, In: Acta Neuropathologica Communications. 11, 1, 68.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Amyloid 100%
  • Alzheimer Disease 81%
  • Amyloidosis 58%
  • Genes 42%
  • Brain 38%
  1 Scopus citations

• Location of pathogenic variants in PSEN1 impacts progression of cognitive, clinical, and neurodegenerative measures in autosomal-dominant Alzheimer's disease

  Schultz, S. A., Shirzadi, Z., Schultz, A. P., Liu, L., Fitzpatrick, C. D., McDade, E., Barthelemy, N. R., Renton, A., Esposito, B., Joseph-Mathurin, N., Cruchaga, C., Chen, C. D., Goate, A., Allegri, R. F., Benzinger, T. L. S., Berman, S., Chui, H. C., Fagan, A. M., Farlow, M. R., Fox, N. C., & 27 othersGordon, B. A., Day, G., Graff-Radford, N. R., Hassenstab, J. J., Hanseeuw, B. J., Hofmann, A., Jack, C. R., Jucker, M., Karch, C. M., Koeppe, R. A., Lee, J. H., Levey, A. I., Levin, J., Martins, R. N., Mori, H., Morris, J. C., Noble, J., Perrin, R. J., Rosa-Neto, P., Salloway, S. P., Sanchez-Valle, R., Schofield, P. R., Xiong, C., Johnson, K. A., Bateman, R. J., Sperling, R. A. & Chhatwal, J. P., Aug 2023, In: Aging Cell. 22, 8, e13871.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Alzheimer Disease 100%
  • Cognitive Dysfunction 52%
  • Biomarkers 41%
  • Amyloid Precursor Protein Secretases 39%
  • Spinal Puncture 38%

• Longitudinal Relationships of White Matter Hyperintensities and Alzheimer Disease Biomarkers Across the Adult Life Span

  Luo, J., Ma, Y., Agboola, F. J., Grant, E., Morris, J. C., Mcdade, E., Fagan, A. M., Benzinger, T. L. S., Hassenstab, J., Bateman, R. J., Perrin, R. J., Gordon, B. A., Goyal, M., Strain, J. F., Yakushev, I., Day, G. S. & Xiong, C., Jul 11 2023, In: Neurology. 101, 2, p. E164-E177

  Research output: Contribution to journal › Article › peer-review

  • Leukoencephalopathies 100%
  • Longevity 67%
  • Alzheimer Disease 58%
  • Biomarkers 48%
  • Amyloid 31%
  2 Scopus citations

• Mapping sleep's oscillatory events as a biomarker of Alzheimer's disease

  Pulver, R. L., Kronberg, E., Medenblik, L. M., Kheyfets, V. O., Ramos, A. R., Holtzman, D. M., Morris, J. C., Toedebusch, C. D., Sillau, S. H., Bettcher, B. M., Lucey, B. P. & McConnell, B. V., 2023, (Accepted/In press) In: Alzheimer's and Dementia.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • sleep 100%
  • dementia 93%
  • Amyloid 87%
  • Electroencephalography 78%
  • cognitive impairment 75%

• Medication and Road Test Performance among Cognitively Healthy Older Adults

  Carr, D. B., Beyene, K., Doherty, J., Murphy, S. A., Johnson, A. M., Domash, H., Riley, N., Walker, A., Sabapathy, A., Morris, J. C. & Babulal, G. M., Sep 29 2023, In: JAMA Network Open. 6, 9, p. E2335651

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Histamine Antagonists 100%
  • Cholinergic Antagonists 95%
  • Hypnotics and Sedatives 87%
  • Antidepressive Agents 77%
  • Anti-Inflammatory Agents 63%

• Metabolomic and lipidomic signatures in autosomal dominant and late-onset Alzheimer's disease brains

  for the Dominantly Inherited Alzheimer Network (DIAN) Study Group, the Alzheimer's Disease Neuroimaging Initiative, and the Alzheimer's Disease Metabolomics Consortium (ADMC), Novotny, B. C., Fernandez, M. V., Wang, C., Budde, J. P., Bergmann, K., Eteleeb, A. M., Bradley, J., Webster, C., Ebl, C., Norton, J., Gentsch, J., Dube, U., Wang, F., Morris, J., Bateman, R. J., Perrin, R. J., McDade, E., & 10 othersXiong, C., Chhatwal, J., Goate, A., Farlow, M., Schofield, P., Chui, H., Karch, C. M., Cruchaga, C., Benitez Viloria, B. A. & Harari, O., May 2023, In: Alzheimer's and Dementia. 19, 5, p. 1785-1799 15 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Lipidomics 100%
  • Metabolomics 80%
  • dementia 73%
  • brain 61%
  • Alzheimer Disease 56%
  4 Scopus citations

• Multimodal brain age estimates relate to Alzheimer disease biomarkers and cognition in early stages: a cross-sectional observational study

  Dominantly Inherited Alzheimer Network, Millar, P. R., Gordon, B. A., Luckett, P. H., Benzinger, T. L. S., Cruchaga, C., Fagan, A. M., Hassenstab, J. J., Perrin, R. J., Schindler, S. E., Allegri, R. F., Day, G. S., Farlow, M. R., Mori, H., Nübling, G., Bateman, R. J., Morris, J. C. & Ances, B. M., 2023, In: eLife. 12, e81869.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Biological Marker 100%
  • Cognition 87%
  • Observational Studies 86%
  • Alzheimer Disease 86%
  • Cross-Sectional Studies 72%
  8 Scopus citations

• Neuroinflammation: A Modifiable Pathway Linking Obesity, Alzheimer's disease, and Depression

  Ly, M., Yu, G. Z., Mian, A., Cramer, A., Meysami, S., Merrill, D. A., Samara, A., Eisenstein, S. A., Hershey, T., Babulal, G. M., Lenze, E. J., Morris, J. C., Benzinger, T. L. S. & Raji, C. A., Oct 2023, In: American Journal of Geriatric Psychiatry. 31, 10, p. 853-866 14 p.

  Research output: Contribution to journal › Review article › peer-review

  • Alzheimer Disease 100%
  • Obesity 89%
  • Depression 84%
  • Metabolically Benign Obesity 27%
  • Pathology 20%
  1 Scopus citations

• Neuroinflammation and amyloid deposition in the progression of mixed Alzheimer and vascular dementia

  Ying, C., Kang, P., Binkley, M. M., Ford, A., Chen, Y., Hassenstab, J., Wang, Q., Strain, J., Morris, J., Lee, J-M., Benzinger, T. & An, H., Jan 2023, In: NeuroImage: Clinical. 38, 103373.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Vascular Dementia 100%
  • (R)-(11C)1-(2-chlorophenyl)-N-methyl-N-(1-methylpropyl)-3-isoquinolinecarboxamide 79%
  • Amyloid 77%
  • Cognitive Dysfunction 67%
  • Alzheimer Disease 63%

• Neuropsychiatric Symptoms and Alzheimer Disease Biomarkers Independently Predict Progression to Incident Cognitive Impairment

  Babulal, G. M., Chen, L., Murphy, S. A., Doherty, J. M., Johnson, A. M. & Morris, J. C., Dec 2023, In: American Journal of Geriatric Psychiatry. 31, 12, p. 1190-1199 10 p.

  Research output: Contribution to journal › Article › peer-review

  • Cognitive Dysfunction 100%
  • Alzheimer Disease 94%
  • Biomarkers 79%
  • Mental Status and Dementia Tests 76%
  • Positron-Emission Tomography 68%

• Outcome measures for Alzheimer's disease: A global inter-societal Delphi consensus

  Ellison, T. S., Cappa, S. F., Garrett, D., Georges, J., Iwatsubo, T., Kramer, J. H., Lehmann, M., Lyketsos, C., Maier, A. B., Merrilees, J., Morris, J. C., Naismith, S. L., Nobili, F., Pahor, M., Pond, D., Robinson, L., Soysal, P., Vandenbulcke, M., Weber, C. J., Visser, P. J., & 2 othersWeiner, M. & Frisoni, G. B., Jun 2023, In: Alzheimer's and Dementia. 19, 6, p. 2707-2729 23 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • measurement method 100%
  • dementia 80%
  • Consensus 76%
  • quality of life 64%
  • Alzheimer Disease 62%

• Pattern and implications of neurological examination findings in autosomal dominant Alzheimer disease

  for the Dominantly Inherited Alzheimer Network, Feb 2023, In: Alzheimer's and Dementia. 19, 2, p. 632-645 14 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Neurologic Examination 100%
  • dementia 93%
  • Alzheimer Disease 71%
  • examination 53%
  • Atrophy 24%
  2 Scopus citations

• Plasma Aβ42/Aβ40 Ratios in Older People with Human Immunodeficiency Virus

  Cooley, S. A., Nelson, B., Boerwinkle, A., Yarasheski, K. E., Kirmess, K. M., Meyer, M. R., Schindler, S. E., Morris, J. C., Fagan, A., Ances, B. M. & O’Halloran, J. A., May 15 2023, In: Clinical Infectious Diseases. 76, 10, p. 1776-1783 8 p.

  Research output: Contribution to journal › Article › peer-review

  • HIV 100%
  • Alzheimer Disease 84%
  • Amyloid 68%
  • Cognition 19%
  • Amyloidosis 13%

• Plasma glial fibrillary acidic protein in autosomal dominant Alzheimer's disease: Associations with Aβ-PET, neurodegeneration, and cognition

  and the Dominantly Inherited Alzheimer Network, Chatterjee, P., Vermunt, L., Gordon, B. A., Pedrini, S., Boonkamp, L., Armstrong, N. J., Xiong, C., Singh, A. K., Li, Y., Sohrabi, H. R., Taddei, K., Molloy, M., Benzinger, T. L. S., Morris, J. C., Karch, C., Berman, S., Chhatwal, J., Cruchaga, C., Graff-Radford, N. R., & 19 othersDay, G. S., Farlow, M., Fox, N., Goate, A., Hassenstab, J., Lee, J. H., Levin, J., McDade, E., Mori, H., Perrin, R., Sanchez-Valle, R., Schofield, P. R., Levey, A., Jucker, M., Masters, C. L., Fagan, A. M., Bateman, R. J., Martins, R. N. & Teunissen, C., Jul 2023, In: Alzheimer's and Dementia. 19, 7, p. 2790-2804 15 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Glial Fibrillary Acidic Protein 100%
  • dementia 90%
  • Blood Proteins 79%
  • cognition 73%
  • Cognition 70%
  5 Scopus citations

• Positron emission tomography and magnetic resonance imaging methods and datasets within the Dominantly Inherited Alzheimer Network (DIAN)

  the Dominantly Inherited Alzheimer Network, Aug 2023, In: Nature neuroscience. 26, 8, p. 1449-1460 12 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Positron-Emission Tomography 100%
  • Datasets 84%
  • Alzheimer Disease 83%
  • Magnetic Resonance Imaging 71%
  • Neuroimaging 38%
  2 Scopus citations