John Dipersio

2024

Blinatumomab consolidation post–autologous stem cell transplantation in patients with diffuse large B-cell lymphoma

Ghobadi, A., Foley, N. C., Cohen, J., Rettig, M. P., Cashen, A. F., Gehrs, L., Christ, S., Street, E., Wallace, N., Ritchey, J., Mehta-Shah, N., Westervelt, P., Fehniger, T. A., Kahl, B., Bartlett, N. L. & DiPersio, J. F., Feb 13 2024, In: Blood Advances. 8, 3, p. 513-522 10 p.

Research output: Contribution to journal › Article › peer-review

Open Access

Control of acute myeloid leukemia and generation of immune memory in vivo using AMV564, a bivalent bispecific CD33 x CD3 T cell engager

Eissenberg, L. G., Ritchey, J. K., Rettig, M. P., Patel, D. A., Vij, K., Gao, F., Smith, V., Han, T. H. & DiPersio, J. F., May 2024, In: PloS one. 19, 5 MAY, e0300174.

Research output: Contribution to journal › Article › peer-review

Open Access

Novel JAK Inhibitors to Reduce Graft-Versus-Host Disease after Allogeneic Hematopoietic Cell Transplantation in a Preclinical Mouse Model

Kim, S., Ruminski, P., Singh, M., Staser, K., Ashami, K., Ritchey, J., Lim, S., DiPersio, J. F. & Choi, J., Apr 2024, In: Molecules. 29, 8, 1801.

Research output: Contribution to journal › Article › peer-review

Open Access

1 Scopus citations

Recruitment and Retention of Hematopoietic Cell Transplantation and Cellular Therapy Physicians: A Report from the ASTCT Talent Acquisition Task Force

Sharma, A., Czechowicz, A., Mavers, M., Chao, N., DiPersio, J., Reddy, P., Perales, M. A. & Smith, M., Jun 2024, In: Transplantation and Cellular Therapy. 30, 6, p. 559-564 6 p.

Research output: Contribution to journal › Article › peer-review

2023

A Multicenter Phase 2 Clinical Trial of 10-Day Decitabine, Dose-Escalated Donor Lymphocyte Infusion, and Ruxolitinib for Relapsed Acute Myeloid Leukemia and Myelodysplastic Syndromes after Allogeneic Hematopoietic Cell Transplantation

Rashidi, A., Huselton, E. J., Stefanski, H. E., DeFor, T. E., Shanley, R., Choi, J., DiPersio, J. F., Juckett, M., Miller, J. S., Weisdorf, D. J. & Schroeder, M. A., May 2023, In: Transplantation and Cellular Therapy. 29, 5, p. 328.e1-328.e6

Research output: Contribution to journal › Article › peer-review

Open Access

2 Scopus citations

Anti-myeloma efficacy of CAR-iNKT is enhanced with a long-acting IL-7, rhIL-7-hyFc

O’Neal, J., Cooper, M. L., Ritchey, J. K., Gladney, S., Niswonger, J., González, L. S., Street, E., Haas, G. J., Carter, A., Amayta, P. N., Gao, F., Lee, B. H., Choi, D., Berrien-Elliott, M., Zhou, A., Fehniger, T. A., Rettig, M. P. & DiPersio, J. F., Oct 24 2023, In: Blood Advances. 7, 20, p. 6009-6022 14 p.

Research output: Contribution to journal › Article › peer-review

Open Access

8 Scopus citations

An “off-the-shelf” CD2 universal CAR-T therapy for T-cell malignancies

Xiang, J., Devenport, J. M., Carter, A. J., Staser, K. W., Kim, M. Y., O’ Neal, J., Ritchey, J. K., Rettig, M. P., Gao, F., Rettig, G., Turk, R., Lee, B. H., Cooper, M. L. & DiPersio, J. F., Dec 2023, In: Leukemia. 37, 12, p. 2448-2456 9 p.

Research output: Contribution to journal › Article › peer-review

Open Access

9 Scopus citations

Apolipoprotein M Attenuates Anthracycline Cardiotoxicity and Lysosomal Injury

Guo, Z., Valenzuela Ripoll, C., Picataggi, A., Rawnsley, D., Ozcan, M., Chirinos, J. A., Chendamarai, E., Girardi, A., Riehl, T., Evie, H., Diab, A., Kovacs, A., Hyrc, K., Ma, X., Asnani, A., Shewale, S. V., Scherrer-Crosbie, M., Cowart, L. A., Parks, J. S. & Zhao, L. & 14 others, Gordon, D., Ramirez-Valle, F., Margulies, K. B., Cappola, T. P., Desai, A. A., Pedersen, L. N., Bergom, C., Stitziel, N., Rettig, M., Dipersio, J., Hajny, S., Christoffersen, C., Diwan, A. & Javaheri, A., Mar 2023, In: JACC: Basic to Translational Science. 8, 3, p. 340-355 16 p.

Research output: Contribution to journal › Article › peer-review

Open Access

14 Scopus citations

Baricitinib with cyclosporine eliminates acute graft rejection in fully mismatched skin and heart transplant models

Abboud, R., Kim, S., Staser, K., Jayasinghe, R. G., Lim, S., Amatya, P., Frye, C. C., Kopecky, B., Ritchey, J., Gao, F., Lavine, K., Kreisel, D., DiPersio, J. F. & Choi, J., 2023, In: Frontiers in immunology. 14, 1264496.

Research output: Contribution to journal › Article › peer-review

Open Access

1 Scopus citations

Duvelisib for Critically Ill Patients With Coronavirus Disease 2019: An Investigator-Initiated, Randomized, Placebo-Controlled, Double-Blind Pilot Trial

Goldsmith, S. R., Covut, F., Fiala, M., Xiang, Z., Iqbal, Z., Moore, N., Bradtke, E., Christen, B., Rettig, M. P., Christ, S., Gehrs, L., Street, E., Wallace, N., Ritchey, J., Gao, F., Pachter, J., Parikh, B., Dubberke, E. R. & DiPersio, J. F., Nov 1 2023, In: Open Forum Infectious Diseases. 10, 11, ofad518.

Research output: Contribution to journal › Article › peer-review

Open Access

1 Scopus citations

Epigenetic regulation during cancer transitions across 11 tumour types

Terekhanova, N. V., Karpova, A., Liang, W. W., Strzalkowski, A., Chen, S., Li, Y., Southard-Smith, A. N., Iglesia, M. D., Wendl, M. C., Jayasinghe, R. G., Liu, J., Song, Y., Cao, S., Houston, A., Liu, X., Wyczalkowski, M. A., Lu, R. J. H., Caravan, W., Shinkle, A. & Naser Al Deen, N. & 24 others, Herndon, J. M., Mudd, J., Ma, C., Sarkar, H., Sato, K., Ibrahim, O. M., Mo, C. K., Chasnoff, S. E., Porta-Pardo, E., Held, J. M., Pachynski, R., Schwarz, J. K., Gillanders, W. E., Kim, A. H., Vij, R., DiPersio, J. F., Puram, S. V., Chheda, M. G., Fuh, K. C., DeNardo, D. G., Fields, R. C., Chen, F., Raphael, B. J. & Ding, L., Nov 9 2023, In: Nature. 623, 7986, p. 432-441 10 p.

Research output: Contribution to journal › Article › peer-review

Open Access

19 Scopus citations

First-in-Human Evaluation of Safety and Dosimetry of ⁶⁴Cu-LLP2A for PET Imaging

Laforest, R., Ghai, A., Fraum, T. J., Oyama, R., Frye, J., Kaemmerer, H., Gaehle, G., Voller, T., Mpoy, C., Rogers, B. E., Fiala, M., Shoghi, K. I., Achilefu, S., Rettig, M., Vij, R., DiPersio, J. F., Schwarz, S., Shokeen, M. & Dehdashti, F., Feb 1 2023, In: Journal of Nuclear Medicine. 64, 2

Research output: Contribution to journal › Article › peer-review

Open Access

9 Scopus citations

Flotetuzumab and other T-cell immunotherapies upregulate MHC class II expression on acute myeloid leukemia cells

Rimando, J. C., Chendamarai, E., Rettig, M. P., Jayasinghe, R., Christopher, M. J., Ritchey, J. K., Christ, S., Kim, M. Y., Bonvini, E. & DiPersio, J. F., Apr 6 2023, In: Blood. 141, 14, p. 1718-1723 6 p.

Research output: Contribution to journal › Article › peer-review

Open Access

13 Scopus citations

Genomic landscape of TP53-mutated myeloid malignancies

Abel, H. J., Oetjen, K. A., Miller, C. A., Ramakrishnan, S. M., Day, R. B., Helton, N. M., Fronick, C. C., Fulton, R. S., Heath, S. E., Tarnawsky, S. P., Srivatsan, S. N., Duncavage, E. J., Schroeder, M. C., Payton, J. E., Spencer, D. H., Walter, M. J., Westervelt, P., DiPersio, J. F., Ley, T. J. & Link, D. C., Aug 16 2023, In: Blood Advances. 7, 16, p. 4586-4598 13 p.

Research output: Contribution to journal › Article › peer-review

Open Access

10 Scopus citations

Hematopoietic stem cell mobilization for allogeneic stem cell transplantation by motixafortide, a novel CXCR4 inhibitor

Crees, Z. D., Rettig, M. P., Bashey, A., Devine, S. M., Jaglowski, S., Wan, F., Zhou, A., Harding, M., Vainstein-Haras, A., Sorani, E., Gliko-Kabir, I., Grossman, B. J., Westervelt, P., DiPersio, J. F. & Uy, G. L., Sep 26 2023, In: Blood Advances. 7, 18, p. 5210-5214 5 p.

Research output: Contribution to journal › Article › peer-review

Open Access

6 Scopus citations

Immune Adjuvant Therapy With Interleukin-7 in a Lymphopenic Patient With Aplastic Anemia and Mucormycosis

Crees, Z. D., Patel, D. A., Dram, A., Kim, M., Bern, M. D., Eberly, A. R., Augustin, K., Hotchkiss, R. S. & Dipersio, J. F., Oct 19 2023, In: Critical Care Explorations. 5, 10, p. E0990

Research output: Contribution to journal › Article › peer-review

Open Access

1 Scopus citations

Motixafortide and G-CSF to mobilize hematopoietic stem cells for autologous transplantation in multiple myeloma: a randomized phase 3 trial

Crees, Z. D., Rettig, M. P., Jayasinghe, R. G., Stockerl-Goldstein, K., Larson, S. M., Arpad, I., Milone, G. A., Martino, M., Stiff, P., Sborov, D., Pereira, D., Micallef, I., Moreno-Jiménez, G., Mikala, G., Coronel, M. L. P., Holtick, U., Hiemenz, J., Qazilbash, M. H., Hardy, N. & Latif, T. & 12 others, García-Cadenas, I., Vainstein-Haras, A., Sorani, E., Gliko-Kabir, I., Goldstein, I., Ickowicz, D., Shemesh-Darvish, L., Kadosh, S., Gao, F., Schroeder, M. A., Vij, R. & DiPersio, J. F., Apr 2023, In: Nature medicine. 29, 4, p. 869-879 11 p.

Research output: Contribution to journal › Article › peer-review

Open Access

28 Scopus citations

Phase I-II Trial of Early Azacitidine after Matched Unrelated Donor Hematopoietic Cell Transplantation

Xu, Z., Choi, J., Cooper, M., King, J., Fiala, M. A., Liu, J., Pusic, I., Romee, R., Cashen, A., Jacoby, M. A., Stockerl-Goldstein, K., Abboud, C., Vij, R., Uy, G., Westervelt, P., Walter, M. J., DiPersio, J. F. & Schroeder, M. A., Nov 2023, In: Transplantation and Cellular Therapy. 29, 11, p. 699.e1-699.e9

Research output: Contribution to journal › Article › peer-review

1 Scopus citations

S100A9 upregulated by IFNGR signaling blockade functions as a novel GVHD suppressor without compromising GVL in mice

Kim, S., Lim, S., Kim, B., Ritchey, J., Vij, K., Prior, J., Marsala, L., Stoner, A., Gao, F., Achilefu, S., Cooper, M. L., DiPersio, J. F. & Choi, J., Feb 23 2023, In: Blood. 141, 8, p. 945-950 6 p.

Research output: Contribution to journal › Article › peer-review

Open Access

3 Scopus citations

Single-Cell Discovery and Multiomic Characterization of Therapeutic Targets in Multiple Myeloma

Yao, L., Wang, J. T., Jayasinghe, R. G., O’Neal, J., Tsai, C. F., Rettig, M. P., Song, Y., Liu, R., Zhao, Y., Ibrahim, O. M., Fiala, M. A., Fortier, J. M., Chen, S., Gehrs, L., Rodrigues, F. M., Wendl, M. C., Kohnen, D., Shinkle, A., Cao, S. & Foltz, S. M. & 12 others, Zhou, D. C., Storrs, E., Wyczalkowski, M. A., Mani, S., Goldsmith, S. R., Zhu, Y., Hamilton, M., Liu, T., Chen, F., Vij, R., Ding, L. & DiPersio, J. F., Apr 15 2023, In: Cancer research. 83, 8, p. 1214-1233 20 p.

Research output: Contribution to journal › Article › peer-review

Open Access

11 Scopus citations

The menin inhibitor revumenib in KMT2A-rearranged or NPM1-mutant leukaemia

Issa, G. C., Aldoss, I., DiPersio, J., Cuglievan, B., Stone, R., Arellano, M., Thirman, M. J., Patel, M. R., Dickens, D. S., Shenoy, S., Shukla, N., Kantarjian, H., Armstrong, S. A., Perner, F., Perry, J. A., Rosen, G., Bagley, R. G., Meyers, M. L., Ordentlich, P. & Gu, Y. & 4 others, Kumar, V., Smith, S., McGeehan, G. M. & Stein, E. M., Mar 30 2023, In: Nature. 615, 7954, p. 920-924 5 p.

Research output: Contribution to journal › Article › peer-review

Open Access

141 Scopus citations

2022

Ablation of VLA4 in multiple myeloma cells redirects tumor spread and prolongs survival

Hathi, D., Chanswangphuwana, C., Cho, N., Fontana, F., Maji, D., Ritchey, J., O’Neal, J., Ghai, A., Duncan, K., Akers, W. J., Fiala, M., Vij, R., DiPersio, J. F., Rettig, M. & Shokeen, M., Dec 2022, In: Scientific reports. 12, 1, 30.

Research output: Contribution to journal › Article › peer-review

Open Access

12 Scopus citations

A long-acting interleukin-7, rhIL-7-hyFc, enhances CAR T cell expansion, persistence, and anti-tumor activity

Kim, M. Y., Jayasinghe, R., Devenport, J. M., Ritchey, J. K., Rettig, M. P., O’Neal, J., Staser, K. W., Kennerly, K. M., Carter, A. J., Gao, F., Lee, B. H., Cooper, M. L. & DiPersio, J. F., Dec 2022, In: Nature communications. 13, 1, 3296.

Research output: Contribution to journal › Article › peer-review

Open Access

43 Scopus citations

Assessment of Pretreatment and Posttreatment Evolution of Neurofilament Light Chain Levels in Patients Who Develop Immune Effector Cell-Associated Neurotoxicity Syndrome

Butt, O. H., Zhou, A. Y., Caimi, P. F., Luckett, P. H., Wisch, J. K., Derenoncourt, P. R., Lee, K., Wu, G. F., De Lima, M. J. G., Campian, J. L., Frank, M. J., Dipersio, J. F., Ghobadi, A. & Ances, B. M., Nov 17 2022, In: JAMA oncology. 8, 11, p. 1652-1657 6 p.

Research output: Contribution to journal › Article › peer-review

Open Access

4 Scopus citations

Baricitinib prevents GvHD by increasing Tregs via JAK3 and treats established GvHD by promoting intestinal tissue repair via EGFR

Kim, S., Ashami, K., Lim, S., Staser, K., Vij, K., Santhanam, S., Ritchey, J., Peterson, S., Gao, F., Ciorba, M. A., Cooper, M. L., DiPersio, J. F. & Choi, J., Jan 2022, In: Leukemia. 36, 1, p. 292-295 4 p.

Research output: Contribution to journal › Article › peer-review

15 Scopus citations

CML-046 Dose Modification Dynamics of Ponatinib in Patients With Chronic-Phase Chronic Myeloid Leukemia From the PACE and OPTIC Trials

Apperley, J., Kantarjian, H., Deininger, M., Abruzzese, E., Cortes, J., Chuah, C., DeAngelo, D. J., DiPersio, J., Hochhaus, A., Lipton, J. H., Nicolini, F., Pinilla-Ibarz, J., Rea, D., Rosti, G., Rousselot, P., Mauro, M., Shah, N., Talpaz, M., Vorog, A. & Ren, X. & 1 others, Jabbour, E., Oct 2022, In: Clinical Lymphoma, Myeloma and Leukemia. 22, p. S284-S285

Research output: Contribution to journal › Article › peer-review

1 Scopus citations

Comprehensive Characterization of the Check for updates Multiple Myeloma Immune Microenvironment Using Integrated scRNA-seq, CyTOF, and CITE-seq Analysis

Yao, L., Jayasinghe, R. G., Lee, B. H., Bhasin, S. S., Pilcher, W., Doxie, D. B., Gonzalez-Kozlova, E., Dasari, S., Fiala, M. A., Pita-Juarez, Y., Strausbauch, M., Kelly, G., Thomas, B. E., Kumar, S. K., Cho, H. J., Anderson, E., Wendl, M., Dawson, T., D’souza, D. & Oh, S. T. & 17 others, Cheloni, G., Li, Y., DiPersio, J. F., Rahman, A. H., Dhodapkar, K. M., Kim-Schulze, S., Vij, R., Vlachos, I. S., Mehr, S., Hamilton, M., Auclair, D., Kourelis, T., Avigan, D., Dhodapkar, M. V., Gnjatic, S., Bhasin, M. K. & Ding, L., 2022, In: Cancer research communications. 2, 10, p. 1255-1265 11 p.

Research output: Contribution to journal › Article › peer-review

Open Access

13 Scopus citations

Convergent Clonal Evolution of Signaling Gene Mutations Is a Hallmark of Myelodysplastic Syndrome Progression

Menssen, A. J., Khanna, A., Miller, C. A., Srivatsan, S. N., Chang, G. S., Shao, J., Robinson, J., O’Laughlin, M., Fronick, C. C., Fulton, R. S., Brendel, K., Heath, S. E., Saba, R., Welch, J. S., Spencer, D. H., Payton, J. E., Westervelt, P., DiPersio, J. F., Link, D. C. & Schuelke, M. J. & 4 others, Jacoby, M. A., Duncavage, E. J., Ley, T. J. & Walter, M. J., Jul 1 2022, In: Blood cancer discovery. 3, 4, p. 330-345 16 p.

Research output: Contribution to journal › Article › peer-review

Open Access

11 Scopus citations

CS1 CAR-T targeting the distal domain of CS1 (SLAMF7) shows efficacy in high tumor burden myeloma model despite fratricide of CD8+CS1 expressing CAR-T cells

O’Neal, J., Ritchey, J. K., Cooper, M. L., Niswonger, J., Sofía González, L., Street, E., Rettig, M. P., Gladney, S. W., Gehrs, L., Abboud, R., Prior, J. L., Haas, G. J., Jayasinghe, R. G., Ding, L., Ghobadi, A., Vij, R. & DiPersio, J. F., Jun 2022, In: Leukemia. 36, 6, p. 1625-1634 10 p.

Research output: Contribution to journal › Article › peer-review

Open Access

26 Scopus citations

Focal disruption of DNA methylation dynamics at enhancers in IDH-mutant AML cells

Wilson, E. R., Helton, N. M., Heath, S. E., Fulton, R., Payton, J. E., Welch, J., Walter, M., Westervelt, P., DiPersio, J. F., Link, D. C., Miller, C., Ley, T. J. & Spencer, D., Apr 2022, In: Leukemia. 36, 4, p. 935-945 11 p.

Research output: Contribution to journal › Article › peer-review

Open Access

15 Scopus citations

Genetic and Transcriptional Contributions to Relapse in Normal Karyotype Acute Myeloid Leukemia

Petti, A. A., Khan, S. M., Xu, Z., Helton, N., Fronick, C. C., Fulton, R., Ramakrishnan, S. M., Srivatsan, S. N., Heath, S. E., Westervelt, P., Payton, J. E., Walter, M. J., Link, D. C., DiPersio, J., Miller, C. & Ley, T. J., Jan 1 2022, In: Blood cancer discovery. 3, 1, p. 32-49 18 p.

Research output: Contribution to journal › Article › peer-review

Open Access

11 Scopus citations

Hematopoietic cell transplantation donor-derived memory-like NK cells functionally persist after transfer into patients with leukemia

Berrien-Elliott, M. M., Foltz, J. A., Russler-Germain, D. A., Neal, C. C., Tran, J., Gang, M., Wong, P., Fisk, B., Cubitt, C. C., Marin, N. D., Zhou, A. Y., Jacobs, M. T., Foster, M., Schappe, T., McClain, E., Kersting-Schadek, S., Desai, S., Pence, P., Becker-Hapak, M. & Eisele, J. & 20 others, Mosior, M., Marsala, L., Griffith, O. L., Griffith, M., Khan, S. M., Spencer, D. H., DiPersio, J. F., Romee, R., Uy, G. L., Abboud, C. N., Ghobadi, A., Westervelt, P., Stockerl-Goldstein, K., Schroeder, M. A., Wan, F., Lie, W. R., Soon-Shiong, P., Petti, A., Cashen, A. F. & Fehniger, T. A., Feb 23 2022, In: Science translational medicine. 14, 633, abm1375.

Research output: Contribution to journal › Article › peer-review

61 Scopus citations

Heparanase Blockade as a Novel Dual-Targeting Therapy for COVID-19

Xiang, J., Lu, M., Shi, M., Cheng, X., Kwakwa, K. A., Davis, J. L., Su, X., Bakewell, S. J., Zhang, Y., Fontana, F., Xu, Y., Veis, D. J., DiPersio, J. F., Ratner, L., Sanderson, R. D., Noseda, A., Mollah, S., Li, J. & Weilbaecher, K. N., Apr 2022, In: Journal of virology. 96, 7, e00057-22.

Research output: Contribution to journal › Article › peer-review

Open Access

15 Scopus citations

Liposomal phytohemagglutinin: In vivo T-cell activator as a novel pan-cancer immunotherapy

Alhallak, K., Sun, J., Muz, B., Jeske, A., O’Neal, J., Ritchey, J. K., Achilefu, S., DiPersio, J. F. & Azab, A. K., Feb 2022, In: Journal of Cellular and Molecular Medicine. 26, 3, p. 940-944 5 p.

Research output: Contribution to journal › Article › peer-review

Open Access

7 Scopus citations

Machine learning–based scoring models to predict hematopoietic stem cell mobilization in allogeneic donors

Xiang, J., Shi, M., Fiala, M. A., Gao, F., Rettig, M. P., Uy, G. L., Schroeder, M. A., Weilbaecher, K. N., Stockerl-Goldstein, K. E., Mollah, S. & DiPersio, J. F., Apr 12 2022, In: Blood Advances. 6, 7, p. 1991-2000 10 p.

Research output: Contribution to journal › Article › peer-review

Open Access

15 Scopus citations

NIH SenNet Consortium to map senescent cells throughout the human lifespan to understand physiological health

Stanford TDA, University of Connecticut TMC, University of Michigan TDA, University of Minnesota TMC, University of Pittsburgh TMC, University of Washington TDA, Washington University TMC, Yale TMC, SenNet Consortium, Writing Group, Brown University TDA, Buck Institute for Research on Aging TMC/TDA, Consortium Organization and Data Coordinating Center (CODCC), Columbia TMC, Duke University TMC, Massachusetts General Hospital TDA, Mayo Clinic TDA & National Institute of Health (NIH), Dec 2022, In: Nature Aging. 2, 12, p. 1090-1100 11 p.

Research output: Contribution to journal › Article › peer-review

Open Access

37 Scopus citations

Ponatinib after failure of second-generation tyrosine kinase inhibitor in resistant chronic-phase chronic myeloid leukemia

Kantarjian, H. M., Jabbour, E., Deininger, M., Abruzzese, E., Apperley, J., Cortes, J., Chuah, C., DeAngelo, D. J., DiPersio, J., Hochhaus, A., Lipton, J., Nicolini, F. E., Pinilla-Ibarz, J., Rea, D., Rosti, G., Rousselot, P., Shah, N. P., Talpaz, M., Srivastava, S. & Ren, X. & 1 others, Mauro, M., Nov 2022, In: American journal of hematology. 97, 11, p. 1419-1426 8 p.

Research output: Contribution to journal › Article › peer-review

Open Access

23 Scopus citations

Proteomic and phosphoproteomic landscapes of acute myeloid leukemia

Kramer, M. H., Zhang, Q., Sprung, R., Day, R. B., Erdmann-Gilmore, P., Li, Y., Xu, Z., Helton, N. M., George, D. R., Mi, Y., Westervelt, P., Payton, J. E., Ramakrishnan, S. M., Miller, C. A., Link, D. C., DiPersio, J. F., Walter, M. J., Townsend, R. R. & Ley, T. J., Sep 29 2022, In: Blood. 140, 13, p. 1533-1548 16 p.

Research output: Contribution to journal › Article › peer-review

Open Access

38 Scopus citations

Safety analysis of patients who received ruxolitinib for steroid-refractory acute or chronic graft-versus-host disease in an expanded access program

Schroeder, M. A., Hari, P. N., Blithe, A., Paranagama, D., Bhatt, V. & DiPersio, J. F., Jun 2022, In: Bone Marrow Transplantation. 57, 6, p. 975-981 7 p.

Research output: Contribution to journal › Article › peer-review

5 Scopus citations

Systemic IL-15 promotes allogeneic cell rejection in patients treated with natural killer cell adoptive therapy

Berrien-Elliott, M. M., Becker-Hapak, M., Cashen, A. F., Jacobs, M., Wong, P., Foster, M., McClain, E., Desai, S., Pence, P., Cooley, S., Brunstein, C., Gao, F., Abboud, C. N., Uy, G. L., Westervelt, P., Jacoby, M. A., Pusic, I., Stockerl-Goldstein, K. E., Schroeder, M. A. & DiPersio, J. F. & 3 others, Soon-Shiong, P., Miller, J. S. & Fehniger, T. A., Feb 24 2022, In: Blood. 139, 8, p. 1177-1183 7 p.

Research output: Contribution to journal › Article › peer-review

Open Access

59 Scopus citations

The role of allogeneic transplant for adult Ph⁺ ALL in CR1 with complete molecular remission: a retrospective analysis

Ghobadi, A., Slade, M., Kantarjian, H., Alvarenga, J., Aldoss, I., Mohammed, K. A., Jabbour, E., Faramand, R., Shah, B., Locke, F., Fingrut, W., Park, J. H., Short, N. J., Gao, F., Uy, G. L., Westervelt, P., DiPersio, J. F., Champlin, R. E., Al Malki, M. M. & Ravandi, F. & 1 others, Kebriaei, P., Nov 17 2022, In: Blood. 140, 20, p. 2101-2112 12 p.

Research output: Contribution to journal › Article › peer-review

Open Access

33 Scopus citations

Upfront Alternative Donor Transplant versus Immunosuppressive Therapy in Patients with Severe Aplastic Anemia Who Lack a Fully HLA-Matched Related Donor: Systematic Review and Meta-Analysis of Retrospective Studies, on Behalf of the Severe Aplastic Anemia Working Party of the European Group for Blood and Marrow Transplantation

Alotaibi, H., Aljurf, M., de Latour, R., Alfayez, M., Bacigalupo, A., Fakih, R. E., Schrezenmeier, H., Ahmed, S. O., Gluckman, E., Iqbal, S., Höchsmann, B., Halkes, C., de la Fuente, J., Alshehry, N., Cesaro, S., Passweg, J., Dufour, C., Risitano, A. M., DiPersio, J. & Motabi, I., Feb 2022, In: Transplantation and Cellular Therapy. 28, 2, p. 105.e1-105.e7

Research output: Contribution to journal › Article › peer-review

Open Access

10 Scopus citations

2021

3D tissue engineered plasma cultures support leukemic proliferation and induces drug resistance

Alhallak, K., de la Puente, P., Jeske, A., Sun, J., Muz, B., Rettig, M. P., Sahin, I., Weisberg, E. L., Griffin, J. D., Reagan, J. L., DiPersio, J. F. & Azab, A. K., 2021, In: Leukemia and Lymphoma. 62, 10, p. 2457-2465 9 p.

Research output: Contribution to journal › Article › peer-review

7 Scopus citations

Antibody-drug conjugates plus Janus kinase inhibitors enable MHC-mismatched allogeneic hematopoietic stem cell transplantation

Persaud, S. P., Ritchey, J. K., Kim, S., Lim, S., Ruminski, P. G., Cooper, M. L., Rettig, M. P., Choi, J. & DiPersio, J. F., Dec 1 2021, In: Journal of Clinical Investigation. 131, 24, e145501.

Research output: Contribution to journal › Article › peer-review

Open Access

14 Scopus citations

A phase I trial evaluating the effects of plerixafor, G-CSF, and azacitidine for the treatment of myelodysplastic syndromes

Huselton, E., Rettig, M. P., Fletcher, T., Ritchey, J., Gehrs, L., McFarland, K., Christ, S., Eades, W. C., Trinkaus, K., Romee, R., Kulkarni, S., Ghobadi, A., Abboud, C., Cashen, A. F., Stockerl-Goldstein, K., Uy, G. L., Vij, R., Westervelt, P., DiPersio, J. F. & Schroeder, M. A., 2021, In: Leukemia and Lymphoma. 62, 6, p. 1441-1449 9 p.

Research output: Contribution to journal › Article › peer-review

4 Scopus citations

A pilot study of 3D tissue-engineered bone marrow culture as a tool to predict patient response to therapy in multiple myeloma

Alhallak, K., Jeske, A., de la Puente, P., Sun, J., Fiala, M., Azab, F., Muz, B., Sahin, I., Vij, R., DiPersio, J. F. & Azab, A. K., Dec 2021, In: Scientific reports. 11, 1, 19343.

Research output: Contribution to journal › Article › peer-review

Open Access

7 Scopus citations

BL-8040 CXCR4 antagonist is safe and demonstrates antileukemic activity in combination with cytarabine for the treatment of relapsed/refractory acute myelogenous leukemia: An open-label safety and efficacy phase 2a study

Borthakur, G., Ofran, Y., Tallman, M. S., Foran, J., Uy, G. L., DiPersio, J. F., Showel, M. M., Shimoni, A., Nagler, A., Rowe, J. M., Altman, J. K., Abraham, M., Peled, A., Shaw, S., Bohana-Kashtan, O., Sorani, E., Pereg, Y., Foley-Comer, A., Oberkovitz, G. & Lustig, T. M. & 10 others, Glicko-Kabir, I., Aharon, A., Vainstein-Haras, A., Kadosh, S. E., Samara, E., Al-Rawi, A. N., Pemmaraju, N., Bueso-Ramos, C., Cortes, J. E. & Andreeff, M., Apr 15 2021, In: Cancer. 127, 8, p. 1246-1259 14 p.

Research output: Contribution to journal › Article › peer-review

Open Access

26 Scopus citations

CD7-deleted hematopoietic stem cells can restore immunity after CAR T cell therapy

Kim, M. Y., Cooper, M., Jacobs, M. T., Ritchey, J. K., Hollaway, J., Fehniger, T. A. & DiPersio, J. F., Aug 23 2021, In: JCI Insight. 6, 16, e149819.

Research output: Contribution to journal › Article › peer-review

Open Access

22 Scopus citations

Co-evolution of tumor and immune cells during progression of multiple myeloma

Liu, R., Gao, Q., Foltz, S. M., Fowles, J. S., Yao, L., Wang, J. T., Cao, S., Sun, H., Wendl, M. C., Sethuraman, S., Weerasinghe, A., Rettig, M. P., Storrs, E. P., Yoon, C. J., Wyczalkowski, M. A., McMichael, J. F., Kohnen, D. R., King, J., Goldsmith, S. R. & O’Neal, J. & 9 others, Fulton, R. S., Fronick, C. C., Ley, T. J., Jayasinghe, R. G., Fiala, M. A., Oh, S. T., DiPersio, J. F., Vij, R. & Ding, L., Dec 1 2021, In: Nature communications. 12, 1, 2559.

Research output: Contribution to journal › Article › peer-review

Open Access

75 Scopus citations

Combination of dociparstat sodium (DSTAT), a CXCL12/CXCR4 inhibitor, with azacitidine for the treatment of hypomethylating agent refractory AML and MDS

Huselton, E., Rettig, M. P., Campbell, K., Cashen, A. F., DiPersio, J. F., Gao, F., Jacoby, M. A., Pusic, I., Romee, R., Schroeder, M. A., Uy, G. L., Marcus, S. & Westervelt, P., Nov 2021, In: Leukemia Research. 110, 106713.

Research output: Contribution to journal › Article › peer-review

Open Access

9 Scopus citations

John Dipersio

Research output

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