Joel Perlmutter

2021

Quality of life in isolated dystonia: Non-motor manifestations matter

Junker, J., Berman, B. D., Hall, J., Wahba, D. W., Brandt, V., Perlmutter, J. S., Jankovic, J., Malaty, I. A., Wagle Shukla, A., Reich, S. G., Espay, A. J., Duque, K. R., Patel, N., Roze, E., Vidailhet, M., Jinnah, H. A. & Brüggemann, N., Jun 1 2021, In: Journal of Neurology, Neurosurgery and Psychiatry. 92, 6, p. 622-628 7 p.

Research output: Contribution to journal › Article › peer-review

15 Scopus citations

Resting-State Functional Connectivity Predicts STN DBS Clinical Response

Younce, J. R., Campbell, M. C., Hershey, T., Tanenbaum, A. B., Milchenko, M., Ushe, M., Karimi, M., Tabbal, S. D., Kim, A. E., Snyder, A. Z., Perlmutter, J. S. & Norris, S. A., Mar 2021, In: Movement Disorders. 36, 3, p. 662-671 10 p.

Research output: Contribution to journal › Article › peer-review

18 Scopus citations

Revisiting FDA approval of aducanumab

Alexander, G. C., Knopman, D. S., Emerson, S. S., Ovbiagele, B., Kryscio, R. J., Perlmutter, J. S. & Kesselheim, A. S., Aug 26 2021, In: New England Journal of Medicine. 385, 9, p. 769-771 3 p.

Research output: Contribution to journal › Review article › peer-review

76 Scopus citations

Spatially constrained kinetic modeling with dual reference tissues improves ¹⁸F-flortaucipir PET in studies of Alzheimer disease

Zhou, Y., Flores, S., Mansor, S., Hornbeck, R. C., Tu, Z., Perlmutter, J. S., Ances, B., Morris, J. C., Gropler, R. J. & Benzinger, T. L. S., Sep 2021, In: European Journal of Nuclear Medicine and Molecular Imaging. 48, 10, p. 3172-3186 15 p.

Research output: Contribution to journal › Article › peer-review

2 Scopus citations

The Dystonia Coalition: A Multicenter Network for Clinical and Translational Studies

Kilic-Berkmen, G., Wright, L. J., Perlmutter, J. S., Comella, C., Hallett, M., Teller, J., Pirio Richardson, S., Peterson, D. A., Cruchaga, C., Lungu, C. & Jinnah, H. A., Apr 8 2021, In: Frontiers in Neurology. 12, 660909.

Research output: Contribution to journal › Review article › peer-review

Open Access

9 Scopus citations

2020

11C]dihydrotetrabenazine Positron Emission Tomography in Manganese-Exposed Workers

Criswell, S. R., Nielsen, S. S., Warden, M. N., Perlmutter, J. S., Moerlein, S. M., Sheppard, L., Lenox-Krug, J., Checkoway, H. & Racette, B. A., Oct 1 2020, In: Journal of occupational and environmental medicine. 62, 10, p. 788-794 7 p.

Research output: Contribution to journal › Article › peer-review

3 Scopus citations

A clinical trial of isradipine: What went wrong?

Maiti, B. & Perlmutter, J. S., May 5 2020, In: Annals of internal medicine. 172, 9, p. 625-626 2 p.

Research output: Contribution to journal › Editorial

8 Scopus citations

APOE genotype regulates pathology and disease progression in synucleinopathy

Davis, A. A., Inman, C. E., Wargel, Z. M., Dube, U., Freeberg, B. M., Galluppi, A., Haines, J. N., Dhavale, D. D., Miller, R., Choudhury, F. A., Sullivan, P. M., Cruchaga, C., Perlmutter, J. S., Ulrich, J. D., Benitez, B. A., Kotzbauer, P. T. & Holtzman, D. M., Feb 5 2020, In: Science translational medicine. 12, 529, eaay3069.

Research output: Contribution to journal › Article › peer-review

72 Scopus citations

Bilateral subthalamic nucleus deep brain stimulation in elderly patients with parkinson disease: A case-control study

Mitchell, K. T., Younce, J. R., Norris, S. A., Tabbal, S. D., Dowling, J. L., Rich, K. M., Perlmutter, J. S. & Ushe, M., Sep 1 2020, In: Operative Neurosurgery. 19, 3, p. 234-240 7 p.

Research output: Contribution to journal › Article › peer-review

3 Scopus citations

Clinical and Demographic Characteristics of Upper Limb Dystonia

Norris, S. A., Jinnah, H. A., Klein, C., Jankovic, J., Berman, B. D., Roze, E., Mahajan, A., Espay, A. J., Murthy, A. V., Fung, V. S. C., LeDoux, M. S., Chang, F. C. F., Vidailhet, M., Testa, C., Barbano, R., Malaty, I. A., Bäumer, T., Loens, S., Wright, L. J. & Perlmutter, J. S., Nov 2020, In: Movement Disorders. 35, 11, p. 2086-2090 5 p.

Research output: Contribution to journal › Article › peer-review

5 Scopus citations

Cognitive correlates of cerebellar resting-state functional connectivity in Parkinson disease

Maiti, B., Koller, J. M., Snyder, A. Z., Tanenbaum, A. B., Norris, S. A., Campbell, M. C. & Perlmutter, J. S., Jan 28 2020, In: Neurology. 94, 4, p. e384-e396

Research output: Contribution to journal › Article › peer-review

22 Scopus citations

Defining research priorities in dystonia

Lungu, C., Ozelius, L., Standaert, D., Hallett, M., Sieber, B. A., Swanson-Fisher, C., Berman, B. D., Calakos, N., Moore, J. C., Perlmutter, J. S., Pirio Richardson, S. E., Saunders-Pullman, R., Scheinfeldt, L., Sharma, N., Sillitoe, R., Simonyan, K., Starr, P. A., Taylor, A., Vitek, J. & Lungu, C., Mar 24 2020, In: Neurology. 94, 12, p. 526-537 12 p.

Research output: Contribution to journal › Article › peer-review

16 Scopus citations

Dopamine D3 receptor: A neglected participant in Parkinson Disease pathogenesis and treatment?

Yang, P., Perlmutter, J. S., Benzinger, T. L. S., Morris, J. C. & Xu, J., Jan 2020, In: Ageing Research Reviews. 57, 100994.

Research output: Contribution to journal › Review article › peer-review

Open Access

44 Scopus citations

Effects of subthalamic nucleus deep brain stimulation and levodopa on balance in people with parkinson’s disease: A cross sectional study

May, D. S., van Dillen, L. R., Earhart, G. M., Rawson, K. S., Perlmutter, J. S. & Duncan, R. P., Oct 2020, In: Brain Sciences. 10, 10, p. 1-8 8 p., 693.

Research output: Contribution to journal › Article › peer-review

Open Access

2 Scopus citations

Functional genomic analyses uncover APOE-mediated regulation of brain and cerebrospinal fluid beta-amyloid levels in Parkinson disease

Ibanez, L., Bahena, J. A., Yang, C., Dube, U., Farias, F. H. G., Budde, J. P., Bergmann, K., Brenner-Webster, C., Morris, J. C., Perrin, R. J., Cairns, N. J., O’Donnell, J., Álvarez, I., Diez-Fairen, M., Aguilar, M., Miller, R., Davis, A. A., Pastor, P., Kotzbauer, P., Campbell, M. C., & 5 othersPerlmutter, J. S., Rhinn, H., Harari, O., Cruchaga, C. & Benitez, B. A., Dec 2020, In: Acta Neuropathologica Communications. 8, 1, 196.

Research output: Contribution to journal › Article › peer-review

Open Access

6 Scopus citations

It's tricky: Rating alleviating maneuvers in cervical dystonia

Cisneros, E., Stebbins, G. T., Chen, Q., Vu, J. P., Benadof, C. N., Zhang, Z., Barbano, R. L., Fox, S. H., Goetz, C. G., Jankovic, J., Jinnah, H. A., Perlmutter, J. S., Adler, C. H., Factor, S. A., Reich, S. G., Rodriguez, R., Severt, L. L., Stover, N. P., Berman, B. D., Comella, C. L., & 1 othersPeterson, D. A., Dec 15 2020, In: Journal of the Neurological Sciences. 419, 117205.

Research output: Contribution to journal › Article › peer-review

4 Scopus citations

Little Change in Functional Brain Networks Following Acute Levodopa in Drug-Naïve Parkinson's Disease

White, R. L., Campbell, M. C., Yang, D., Shannon, W., Snyder, A. Z. & Perlmutter, J. S., Mar 1 2020, In: Movement Disorders. 35, 3, p. 499-503 5 p.

Research output: Contribution to journal › Article › peer-review

8 Scopus citations

Microglia implicated in tauopathy in the striatum of neurodegenerative disease patients from genotype to phenotype

Li, H., Knight, W. C., Yang, P., Guo, Y., Perlmutter, J. S., Morris, J. C., Bateman, R. J., Benzinger, T. L. S. & Xu, J., Sep 1 2020, In: International journal of molecular sciences. 21, 17, p. 1-23 23 p., 6047.

Research output: Contribution to journal › Article › peer-review

Open Access

6 Scopus citations

Parkinson disease clinical subtypes: key features & clinical milestones

Campbell, M. C., Myers, P. S., Weigand, A. J., Foster, E. R., Cairns, N. J., Jackson, J. J., Lessov-Schlaggar, C. N. & Perlmutter, J. S., Aug 1 2020, In: Annals of Clinical and Translational Neurology. 7, 8, p. 1272-1283 12 p.

Research output: Contribution to journal › Article › peer-review

Open Access

20 Scopus citations

Parkinson's disease - What's the fus?

Perlmutter, J. S. & Ushe, M., Dec 24 2020, In: New England Journal of Medicine. 383, 26, p. 2582-2584 3 p.

Research output: Contribution to journal › Editorial

2 Scopus citations

Postural directionality and head tremor in cervical dystonia

Chen, Q., Vu, J. P., Cisneros, E., Benadof, C. N., Zhang, Z., Barbano, R. L., Goetz, C. G., Jankovic, J., Jinnah, H. A., Perlmutter, J. S., Appelbaum, M. I., Stebbins, G. T., Comella, C. L. & Peterson, D. A., Jan 1 2020, In: Tremor and Other Hyperkinetic Movements. 10, p. 1-6 6 p.

Research output: Contribution to journal › Article › peer-review

6 Scopus citations

Proteinopathy and longitudinal changes in functional connectivity networks in Parkinson disease

Campbell, M. C., Jackson, J. J., Koller, J. M., Snyder, A. Z., Kotzbauer, P. T. & Perlmutter, J. S., Feb 18 2020, In: Neurology. 94, 7, p. e718-e728

Research output: Contribution to journal › Article › peer-review

16 Scopus citations

Psychometric properties and responsiveness of Neuro-QoL Cognitive Function in persons with Huntington disease (HD)

Carlozzi, N. E., Boileau, N. R., Paulsen, J. S., Downing, N. R., Ready, R., Perlmutter, J. S., Cella, D., Chou, K. L., McCormack, M. K., Barton, S. & Lai, J. S., May 1 2020, In: Quality of Life Research. 29, 5, p. 1393-1403 11 p.

Research output: Contribution to journal › Article › peer-review

5 Scopus citations

Radiolabeled 6-(2, 3-dichlorophenyl)-n4-methylpyrimidine-2, 4-diamine (th287): A potential radiotracer for measuring and imaging mth1

Chen, H., Afrin, S., Guo, Y., Chu, W., Benzinger, T. L. S., Rogers, B. E., Garbow, J. R., Perlmutter, J. S., Zhou, D. & Xu, J., Nov 2 2020, In: International journal of molecular sciences. 21, 22, p. 1-16 16 p., 8860.

Research output: Contribution to journal › Article › peer-review

Open Access

2 Scopus citations

Regional, not global, functional connectivity contributes to isolated focal dystonia

Norris, S. A., Morris, A. E., Campbell, M. C., Karimi, M., Adeyemo, B., Paniello, R. C., Snyder, A. Z., Petersen, S. E., Mink, J. W. & Perlmutter, J. S., Oct 20 2020, In: Neurology. 95, 16, p. E2246-E2258

Research output: Contribution to journal › Article › peer-review

15 Scopus citations

Removal of high frequency contamination from motion estimates in single-band fMRI saves data without biasing functional connectivity

Gratton, C., Dworetsky, A., Coalson, R. S., Adeyemo, B., Laumann, T. O., Wig, G. S., Kong, T. S., Gratton, G., Fabiani, M., Barch, D. M., Tranel, D., Miranda-Dominguez, O., Fair, D. A., Dosenbach, N. U. F., Snyder, A. Z., Perlmutter, J. S., Petersen, S. E. & Campbell, M. C., Aug 15 2020, In: NeuroImage. 217, 116866.

Research output: Contribution to journal › Article › peer-review

Open Access

25 Scopus citations

Responsiveness to change over time and test-retest reliability of the PROMIS and Neuro-QoL mental health measures in persons with Huntington disease (HD)

Carlozzi, N. E., Boileau, N. R., Roché, M. W., Ready, R. E., Perlmutter, J. S., Chou, K. L., Barton, S. K., McCormack, M. K., Stout, J. C., Cella, D., Miner, J. A. & Paulsen, J. S., Dec 2020, In: Quality of Life Research. 29, 12, p. 3419-3439 21 p.

Research output: Contribution to journal › Article › peer-review

8 Scopus citations

Safety and tolerability of srx246, a vasopressin 1a antagonist, in irritable huntington’s disease patients—a randomized phase 2 clinical trial

Brownstein, M. J., Simon, N. G., Long, J. D., Yankey, J., Maibach, H. T., Cudkowicz, M., Coffey, C., Conwit, R. A., Lungu, C., Anderson, K. E., Hersch, S. M., Ecklund, D. J., Damiano, E. M., Itzkowitz, D. E., Lu, S., Chase, M. K., Shefner, J. M., McGarry, A., Thornell, B., Gladden, C., & 46 othersCostigan, M., O’suilleabhain, P., Marshall, F. J., Chesire, A. M., Deritis, P., Adams, J. L., Hedera, P., Lowen, K., Diana Rosas, H., Hiller, A. L., Quinn, J., Keith, K., Duker, A. P., Gruenwald, C., Molloy, A., Jacob, C., Factor, S., Sperin, E., Bega, D., Brown, Z. R., Seeberger, L. C., Sung, V. W., Benge, M., Kostyk, S. K., Daley, A. M., Perlman, S., Suski, V., Conlon, P., Barrett, M. J., Lowenhaupt, S., Quigg, M., Perlmutter, J. S., Wright, B. A., Most, E., Schwartz, G. J., Lamb, J., Chuang, R. S., Singer, C., Marder, K., Moran, J. A., Singleton, J. R., Zorn, M., Wall, P. V., Dubinsky, R. M., Gray, C. & Drazinic, C., Nov 2020, In: Journal of Clinical Medicine. 9, 11, p. 1-14 14 p., 3682.

Research output: Contribution to journal › Article › peer-review

Open Access

7 Scopus citations

Structure-activity relationship studies and bioactivity evaluation of 1,2,3-triazole containing analogues as a selective sphingosine kinase-2 inhibitors

Tangadanchu, V. K. R., Jiang, H., Yu, Y., Graham, T. J. A., Liu, H., Rogers, B. E., Gropler, R., Perlmutter, J. & Tu, Z., Nov 15 2020, In: European Journal of Medicinal Chemistry. 206, 112713.

Research output: Contribution to journal › Article › peer-review

4 Scopus citations

The impact of dopamine D₂-like agonist/antagonist on [¹⁸F]VAT PET measurement of VAChT in the brain of nonhuman primates

Liu, H., Luo, Z., Gu, J., Su, Y., Flores, H., Parsons, S. M., Zhou, Y., Perlmutter, J. S. & Tu, Z., Feb 15 2020, In: European Journal of Pharmaceutical Sciences. 143, 105152.

Research output: Contribution to journal › Article › peer-review

3 Scopus citations

The interactions of dopamine and oxidative damage in the striatum of patients with neurodegenerative diseases

Li, H., Yang, P., Knight, W., Guo, Y., Perlmutter, J. S., Benzinger, T. L. S., Morris, J. C. & Xu, J., Jan 1 2020, In: Journal of Neurochemistry. 152, 2, p. 235-251 17 p.

Research output: Contribution to journal › Article › peer-review

Open Access

9 Scopus citations

2019

Automated production of a sphingosine-1 phosphate receptor 1 (S1P1) PET radiopharmaceutical [¹¹C]CS1P1 for human use

Luo, Z., Gu, J., Dennett, R. C., Gaehle, G. G., Perlmutter, J. S., Chen, D. L., Benzinger, T. L. S. & Tu, Z., Oct 2019, In: Applied Radiation and Isotopes. 152, p. 30-36 7 p.

Research output: Contribution to journal › Article › peer-review

3 Scopus citations

Detecting associations between intact connectomes and clinical covariates using recursive partitioning object-oriented data analysis

Yang, D., Deych, E., Shands, B., Campbell, M. C., Perlmutter, J. S., Petersen, S., Schlaggar, B. L. & Shannon, W., Dec 20 2019, In: Statistics in medicine. 38, 29, p. 5486-5496 11 p.

Research output: Contribution to journal › Article › peer-review

1 Scopus citations

Development of a carbon-11 PET radiotracer for imaging TRPC5 in the brain

Yu, Y., Liang, Q., Liu, H., Luo, Z., Hu, H., Perlmutter, J. S. & Tu, Z., 2019, In: Organic and Biomolecular Chemistry. 17, 22, p. 5586-5594 9 p.

Research output: Contribution to journal › Article › peer-review

9 Scopus citations

Dopamine receptor studies with positron emission tomography

Perlmutter, J. S., Aug 15 2019, Functional Imaging in Movement Disorders. Taylor and Francis, p. 83-99 17 p.

Research output: Chapter in Book/Report/Conference proceeding › Chapter › peer-review

Emergent Functional Network Effects in Parkinson Disease

Gratton, C., Koller, J. M., Shannon, W., Greene, D. J., Maiti, B., Snyder, A. Z., Petersen, S. E., Perlmutter, J. S. & Campbell, M. C., Jun 1 2019, In: Cerebral Cortex. 29, 6, p. 2509-2523 15 p.

Research output: Contribution to journal › Article › peer-review

26 Scopus citations

End-of-life measures in Huntington disease: HDQLIFE Meaning and Purpose, Concern with Death and Dying, and End of Life Planning

Carlozzi, N. E., Boileau, N. R., Paulsen, J. S., Perlmutter, J. S., Lai, J. S., Hahn, E. A., McCormack, M. K., Nance, M. A., Cella, D., Barton, S. K. & Downing, N. R., Oct 1 2019, In: Journal of Neurology. 266, 10, p. 2406-2422 17 p.

Research output: Contribution to journal › Article › peer-review

7 Scopus citations

Erratum: Emergent Functional Network Effects in Parkinson Disease (Cerebral Cortex (2018) (1-15) DOI: 10.1093/cercor/bhy121)

Gratton, C., Koller, J. M., Shannon, W., Greene, D. J., Maiti, B., Snyder, A. Z., Petersen, S. E., Perlmutter, J. S. & Campbell, M. C., Apr 1 2019, In: Cerebral Cortex. 29, 4, p. 1701 1 p.

Research output: Contribution to journal › Comment/debate

Open Access

7 Scopus citations

Exercise and Parkinson Disease: Comparing Tango, Treadmill, and Stretching

Rawson, K. S., McNeely, M. E., Duncan, R. P., Pickett, K. A., Perlmutter, J. S. & Earhart, G. M., Jan 1 2019, In: Journal of Neurologic Physical Therapy. 43, 1, p. 26-32 7 p.

Research output: Contribution to journal › Article › peer-review

Open Access

47 Scopus citations

Head tremor at disease onset: an ataxic phenotype of cervical dystonia

Merola, A., Dwivedi, A. K., Shaikh, A. G., Tareen, T. K., Da Prat, G. A., Kauffman, M. A., Hampf, J., Mahajan, A., Marsili, L., Jankovic, J., Comella, C. L., Berman, B. D., Perlmutter, J. S., Jinnah, H. A. & Espay, A. J., Aug 1 2019, In: Journal of Neurology. 266, 8, p. 1844-1851 8 p.

Research output: Contribution to journal › Article › peer-review

Open Access

21 Scopus citations

How different aspects of motor dysfunction influence day-to-day function in huntington's disease

Carlozzi, N. E., Schilling, S. G., Boileau, N. R., Chou, K. L., Perlmutter, J. S., Frank, S., McCormack, M. K., Stout, J. C., Paulsen, J. S., Lai, J. S. & Dayalu, P., Dec 1 2019, In: Movement Disorders. 34, 12, p. 1910-1914 5 p.

Research output: Contribution to journal › Article › peer-review

1 Scopus citations

Low Back Pain - Related Disability in Parkinson Disease: Impact on Functional Mobility, Physical Activity, and Quality of Life

Duncan, R. P., Van Dillen, L. R., Garbutt, J. M., Earhart, G. M. & Perlmutter, J. S., Oct 28 2019, In: Physical therapy. 99, 10, p. 1346-1353 8 p.

Research output: Contribution to journal › Article › peer-review

Open Access

7 Scopus citations

Neuroinflammation and myelin status in Alzheimer's disease, Parkinson's disease, and normal aging brains: A small sample study

Han, F., Perrin, R. J., Wang, Q., Wang, Y., Perlmutter, J. S., Morris, J. C., Benzinger, T. L. S. & Xu, J., 2019, In: Parkinson's Disease. 2019, 7975407.

Research output: Contribution to journal › Article › peer-review

Open Access

23 Scopus citations

Risk of spread in adult-onset isolated focal dystonia: A prospective international cohort study

Berman, B. D., Groth, C. L., Sillau, S. H., Pirio Richardson, S., Norris, S. A., Junker, J., Brüggemann, N., Agarwal, P., Barbano, R. L., Espay, A. J., Vizcarra, J. A., Klein, C., Baümer, T., Loens, S., Reich, S. G., Vidailhet, M., Bonnet, C., Rose, E., Jinnah, H. A. & Perlmutter, J. S., 2019, (Accepted/In press) In: Journal of Neurology, Neurosurgery and Psychiatry. 321794.

Research output: Contribution to journal › Article › peer-review

Open Access

37 Scopus citations

Striatal DAT SPECT: Caveat Emptor!

Perlmutter, J. S. & Stoessl, A. J., Oct 1 2019, In: Movement Disorders. 34, 10, p. 1430-1432 3 p.

Research output: Contribution to journal › Editorial

7 Scopus citations

Thalamic and ventricular volumes predict motor response to deep brain stimulation for Parkinson's disease

Younce, J. R., Campbell, M. C., Perlmutter, J. S. & Norris, S. A., Apr 2019, In: Parkinsonism and Related Disorders. 61, p. 64-69 6 p.

Research output: Contribution to journal › Article › peer-review

16 Scopus citations

2018

[ ¹⁸ F]FDOPA positron emission tomography in manganese-exposed workers

Criswell, S. R., Nielsen, S. S., Warden, M., Perlmutter, J. S., Moerlein, S. M., Flores, H. P., Huang, J., Sheppard, L., Seixas, N., Checkoway, H. & Racette, B. A., Jan 2018, In: NeuroToxicology. 64, p. 43-49 7 p.

Research output: Contribution to journal › Article › peer-review

19 Scopus citations

7T MRI subthalamic nucleus atlas for use with 3T MRI

Milchenko, M., Norris, S. A., Poston, K., Campbell, M. C., Ushe, M., Perlmutter, J. S. & Snyder, A. Z., Jan 1 2018, In: Journal of Medical Imaging. 5, 1, 015002.

Research output: Contribution to journal › Article › peer-review

10 Scopus citations

Agreement between clinician-rated versus patient-reported outcomes in Huntington disease

Carlozzi, N. E., Boileau, N. R., Perlmutter, J. S., Chou, K. L., Stout, J. C., Paulsen, J. S., McCormack, M. K., Cella, D., Nance, M. A., Lai, J. S. & Dayalu, P., Jun 1 2018, In: Journal of Neurology. 265, 6, p. 1443-1453 11 p.

Research output: Contribution to journal › Article › peer-review

7 Scopus citations

A new measure for end of life planning, preparation, and preferences in Huntington disease: HDQLIFE end of life planning

HDQLIFE Site Investigators and Coordinators, Jan 1 2018, In: Journal of Neurology. 265, 1, p. 98-107 10 p.

Research output: Contribution to journal › Article › peer-review

9 Scopus citations

Joel Perlmutter

Research output

Search results