Joel Perlmutter

Research output

Research output per year 1978 2006 2007 2008 2012 2013 2014 2015 2016 2017 2018 2019 2020 2021 2022

• 21111 Citations
• 369 Article
• 15 Review article
• 13 Comment/debate
• 12 Editorial
• 17 More
  • 12 Letter
  • 5 Chapter

Research output per year

Research output per year

Search results

• Levodopa and the progression of parkinson’s disease

  The parkinson study group, Dec 9 2004, In: New England Journal of Medicine. 351, 24, p. 2498-2508 11 p.

  Research output: Contribution to journal › Article › peer-review

  • Levodopa 100%
  • Parkinson Disease 75%
  • Placebos 43%
  • Dopamine Plasma Membrane Transport Proteins 22%
  • Mental Status and Dementia Tests 18%
  1397 Scopus citations

• Levodopa challenge neuroimaging of levodopa-related mood fluctuations in Parkinson's disease

  Black, K. J., Hershey, T., Hartlein, J. M., Carl, J. L. & Perlmutter, J. S., Mar 2005, In: Neuropsychopharmacology. 30, 3, p. 590-601 12 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Levodopa 100%
  • Neuroimaging 81%
  • Parkinson Disease 75%
  • Gyrus Cinguli 66%
  • Regional Blood Flow 58%
  53 Scopus citations

• Levodopa-Responsive Hemiparkinsonism Secondary to Cystic Expansion from a Coiled Cerebral Aneurysm

  Norris, S. A., Derdeyn, C. P. & Perlmutter, J. S., Mar 1 2015, In: Journal of Neuroimaging. 25, 2, p. 316-318 3 p.

  Research output: Contribution to journal › Article › peer-review

  • Levodopa 100%
  • Intracranial Aneurysm 97%
  • Cysts 78%
  • Hemifacial Spasm 64%
  • Dihydroxyphenylalanine 58%

• Levodopa responsive parkinsonism in an adult with Huntington's disease

  Racette, B. A. & Perlmutter, J. S., Oct 1998, In: Journal of Neurology Neurosurgery and Psychiatry. 65, 4, p. 577-579 3 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Levodopa 100%
  • Huntington Disease 99%
  • Parkinsonian Disorders 98%
  • Hypokinesia 75%
  • Westphal disease 64%
  47 Scopus citations

• Little Change in Functional Brain Networks Following Acute Levodopa in Drug-Naïve Parkinson's Disease

  White, R. L., Campbell, M. C., Yang, D., Shannon, W., Snyder, A. Z. & Perlmutter, J. S., Mar 1 2020, In: Movement Disorders. 35, 3, p. 499-503 5 p.

  Research output: Contribution to journal › Article › peer-review

  • Levodopa 100%
  • Parkinson Disease 75%
  • Brain 44%
  • Pharmaceutical Preparations 37%
  • Cross-Over Studies 11%
  6 Scopus citations

• Longitudinal studies of botulinum toxin in cervical dystonia: Why do patients discontinue therapy?

  for the Dystonia Coalition Investigators, Jun 1 2018, In: Toxicon. 147, p. 89-95 7 p.

  Research output: Contribution to journal › Article › peer-review

  • Torticollis 100%
  • Botulinum Toxins 88%
  • Toxin 71%
  • Longitudinal Studies 62%
  • Therapeutics 12%
  29 Scopus citations

• Long term treatment and disease severity change brain responses to levodopa in Parkinson's disease

  Hershey, T., Black, K. J., Carl, J. L., McGee-Minnich, L., Snyder, A. Z. & Perlmutter, J. S., Jul 1 2003, In: Journal of Neurology Neurosurgery and Psychiatry. 74, 7, p. 844-851 8 p.

  Research output: Contribution to journal › Article › peer-review

  • Levodopa 100%
  • Parkinson Disease 75%
  • Brain 44%
  • Therapeutics 14%
  • Corpus Striatum 11%
  55 Scopus citations

• Loss of VPS13C Function in Autosomal-Recessive Parkinsonism Causes Mitochondrial Dysfunction and Increases PINK1/Parkin-Dependent Mitophagy

  Lesage, S., Drouet, V., Majounie, E., Deramecourt, V., Jacoupy, M., Nicolas, A., Cormier-Dequaire, F., Hassoun, S. M., Pujol, C., Ciura, S., Erpapazoglou, Z., Usenko, T., Maurage, C. A., Sahbatou, M., Liebau, S., Ding, J., Bilgic, B., Emre, M., Erginel-Unaltuna, N., Guven, G. & 177 others, Tison, F., Tranchant, C., Vidailhet, M., Corvol, J. C., Krack, P., Leutenegger, A. L., Nalls, M. A., Hernandez, D. G., Heutink, P., Gibbs, J. R., Hardy, J., Wood, N. W., Gasser, T., Durr, A., Deleuze, J. F., Tazir, M., Destée, A., Lohmann, E., Kabashi, E., Singleton, A., Corti, O., Brice, A., Tison, F., Vidailhet, M., Corvol, J. C., Agid, Y., Anheim, M., Bonnet, A. M., Borg, M., Broussolle, E., Damier, P., Destée, A., Dürr, A., Durif, F., Krack, P., Klebe, S., Lohmann, E., Martinez, M., Pollak, P., Rascol, O., Tranchant, C., Vérin, M., Viallet, F., Lesage, S., Majounie, E., Tison, F., Vidailhet, M., Corvol, J. C., Nalls, M. A., Hernandez, D. G., Gibbs, J. R., Dürr, A., Arepalli, S., Barker, R. A., Ben-Shlomo, Y., Berg, D., Bettella, F., Bhatia, K., de Bie, R. M. A., Biffi, A., Bloem, B. R., Bochdanovits, Z., Bonin, M., Bras, J. M., Brockmann, K., Brooks, J., Burn, D. J., Charlesworth, G., Chen, H., Chinnery, P. F., Chong, S., Clarke, C. E., Cookson, M. R., Counsell, C., Damier, P., Dartigues, J. F., Deloukas, P., Deuschl, G., Dexter, D. T., van Dijk, K. D., Dillman, A., Dong, J., Durif, F., Edkins, S., Escott-Price, V., Evans, J. R., Foltynie, T., Gao, J., Gardner, M., Goate, A., Gray, E., Guerreiro, R., Harris, C., van Hilten, J. J., Hofman, A., Hollenbeck, A., Holmans, P., Holton, J., Hu, M., Huang, X., Huber, H., Hudson, G., Hunt, S. E., Huttenlocher, J., Illig, T., Jónsson, P. V., Kilarski, L. L., Jansen, I. E., Lambert, J. C., Langford, C., Lees, A., Lichtner, P., Limousin, P., Lopez, G., Lorenz, D., Lubbe, S., Lungu, C., Martinez, M., Mätzler, W., McNeill, A., Moorby, C., Moore, M., Morrison, K. E., Mudanohwo, E., O’sullivan, S. S., Owen, M. J., Pearson, J., Perlmutter, J. S., Pétursson, H., Plagnol, V., Pollak, P., Post, B., Potter, S., Ravina, B., Revesz, T., Riess, O., Rivadeneira, F., Rizzu, P., Ryten, M., Saad, M., Simón-Sánchez, J., Sawcer, S., Schapira, A., Scheffer, H., Schulte, C., Sharma, M., Shaw, K., Sheerin, U. M., Shoulson, I., Shulman, J., Sidransky, E., Spencer, C. C. A., Stefánsson, H., Stefánsson, K., Stockton, J. D., Strange, A., Talbot, K., Tanner, C. M., Tashakkori-Ghanbaria, A., Trabzuni, D., Traynor, B. J., Uitterlinden, A. G., Velseboer, D., Walker, R., Warrenburg, B. V. D., Wickremaratchi, M., Williams-Gray, C. H., Winder-Rhodes, S., Wurster, I., Williams, N., Morris, H. R., Heutink, P., Hardy, J., Wood, N. W., Gasser, T., Singleton, A. B. & Brice, A., Mar 3 2016, In: American journal of human genetics. 98, 3, p. 500-513 14 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Mitophagy 100%
  • Protein Transport 81%
  • Parkinsonian Disorders 80%
  • Exome 35%
  • Consanguinity 18%
  212 Scopus citations

• Low Back Pain - Related Disability in Parkinson Disease: Impact on Functional Mobility, Physical Activity, and Quality of Life

  Duncan, R. P., Van Dillen, L. R., Garbutt, J. M., Earhart, G. M. & Perlmutter, J. S., Oct 28 2019, In: Physical therapy. 99, 10, p. 1346-1353 8 p.

  Research output: Contribution to journal › Article › peer-review

  • Low Back Pain 100%
  • Parkinson Disease 84%
  • Exercise 65%
  • Quality of Life 64%
  • Elderly 15%
  6 Scopus citations

• Low nigrostriatal reserve for motor parkinsonism in nonhuman primates

  Tabbal, S. D., Tian, L. L., Karimi, M., Brown, C. A., Loftin, S. K. & Perlmutter, J. S., Oct 2012, In: Experimental Neurology. 237, 2, p. 355-362 8 p.

  Research output: Contribution to journal › Article › peer-review

  • Parkinsonian Disorders 100%
  • Substantia Nigra 97%
  • Corpus Striatum 88%
  • Primates 84%
  • Dopamine 76%
  31 Scopus citations

• LRRK2 gene G2019S mutation and SNPs [haplotypes] in subtypes of Parkinson's disease

  Patra, B., Parsian, A. J., Racette, B. A., Zhao, J. H., Perlmutter, J. S. & Parsian, A., Mar 2009, In: Parkinsonism and Related Disorders. 15, 3, p. 175-180 6 p.

  Research output: Contribution to journal › Article › peer-review

  • Leucine 100%
  • Haplotypes 91%
  • Single Nucleotide Polymorphism 81%
  • Parkinson Disease 81%
  • Phosphotransferases 75%
  10 Scopus citations

• Mapping Go-No-Go performance within the subthalamic nucleus region

  Hershey, T., Campbell, M. C., Videen, T. O., Lugar, H. M., Weaver, P. M., Hartlein, J., Karimi, M., Tabbal, S. D. & Perlmutter, J. S., Dec 2010, In: Brain. 133, 12, p. 3625-3634 10 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Subthalamic Nucleus 100%
  • Deep Brain Stimulation 41%
  • Parkinson Disease 24%
  • Basal Ganglia 7%
  • Motor Cortex 7%
  94 Scopus citations

• Mapping movement, mood, motivation and mentation in the subthalamic nucleus

  Gourisankar, A., Eisenstein, S. A., Trapp, N. T., Koller, J. M., Campbell, M. C., Ushe, M., Perlmutter, J. S., Hershey, T. & Black, K. J., Jul 1 2018, In: Royal Society Open Science. 5, 7, 171177.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Subthalamic Nucleus 100%
  • Deep Brain Stimulation 91%
  • Motivation 63%
  • Parkinson Disease 14%
  • Zona Incerta 8%
  19 Scopus citations

• Measures of growth in children at risk for Huntington disease

  Lee, J. K., Mathews, K., Schlaggar, B., Perlmutter, J., Paulsen, J. S., Epping, E., Burmeister, L. & Nopoulos, P., Aug 14 2012, In: Neurology. 79, 7, p. 668-674 7 p.

  Research output: Contribution to journal › Article › peer-review

  • Huntington Disease 100%
  • Growth 45%
  • Child 39%
  • Head 32%
  • Body Mass Index 21%
  54 Scopus citations

• Metabolic control of resting hemispheric cerebral blood flow is oxidative, not glycolytic

  Powers, W. J., Videen, T. O., Markham, J., Walter, V. & Perlmutter, J. S., May 2011, In: Journal of Cerebral Blood Flow and Metabolism. 31, 5, p. 1223-1228 6 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Cerebrovascular Circulation 100%
  • Glucose 46%
  • Oxygen 42%
  • Brain 28%
  • Multivariate Analysis 10%
  16 Scopus citations

• Microglia implicated in tauopathy in the striatum of neurodegenerative disease patients from genotype to phenotype

  Li, H., Knight, W. C., Yang, P., Guo, Y., Perlmutter, J. S., Morris, J. C., Bateman, R. J., Benzinger, T. L. S. & Xu, J., Sep 1 2020, In: International journal of molecular sciences. 21, 17, p. 1-23 23 p., 6047.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Microglia 100%
  • Neurodegenerative diseases 75%
  • phenotype 71%
  • Tauopathies 68%
  • Lewy Body Disease 64%
  3 Scopus citations

• Modified high-performance liquid chromatography with electrochemical detection method for plasma measurement of levodopa, 3-O-methyldopa, dopamine, carbidopa and 3,4-dihydroxyphenyl acetic acid

  Karimi, M., Carl, J. L., Loftin, S. & Perlmutter, J. S., May 19 2006, In: Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences. 836, 1-2, p. 120-123 4 p.

  Research output: Contribution to journal › Article › peer-review

  • 3-O-Methyldopa 100%
  • (3,4-dihydroxyphenyl)acetic Acid 98%
  • 3-methoxytyrosine 91%
  • Carbidopa 86%
  • Levodopa 58%
  80 Scopus citations

• Molecular imaging to track Parkinson's disease and atypical parkinsonisms: New imaging frontiers

  on behalf of IPMDS-Neuroimaging Study Group, Feb 1 2017, In: Movement Disorders. 32, 2, p. 181-192 12 p.

  Research output: Contribution to journal › Review article › peer-review

  • Parkinson Disease, Familial, Type 1 100%
  • Molecular Imaging 74%
  • Parkinsonian Disorders 68%
  • Biomarkers 13%
  • Pathology 13%
  56 Scopus citations

• Mood response to deep brain stimulation of the subthalamic nucleus in Parkinson's disease

  Campbell, M. C., Black, K. J., Weaver, P. M., Lugar, H. M., Videen, T. O., Tabbal, S. D., Karimi, M., Perlmutter, J. S. & Hershey, T., 2012, In: Journal of Neuropsychiatry and Clinical Neurosciences. 24, 1, p. 28-36 9 p.

  Research output: Contribution to journal › Article › peer-review

  • Subthalamic Nucleus 100%
  • Deep Brain Stimulation 91%
  • Parkinson Disease 66%
  • Electrodes 22%
  • Thalamic Nuclei 17%
  33 Scopus citations

• Motor asymmetry and substantia nigra volume are related to spatial delayed response performance in Parkinson disease

  Foster, E. R., Black, K. J., Antenor-Dorsey, J. A. V., Perlmutter, J. S. & Hershey, T., Jun 2008, In: Brain and Cognition. 67, 1, p. 1-10 10 p.

  Research output: Contribution to journal › Article › peer-review

  • Parkinson's Disease 100%
  • Substantia Nigra 60%
  • asymmetry 56%
  • Asymmetry 54%
  • Parkinson Disease 47%
  29 Scopus citations

• Moving the u.s. food and drug administration forward

  Perlmutter, J. S., Nov 1 2021, In: Annals of internal medicine. 174, 11, p. 1626-1627 2 p.

  Research output: Contribution to journal › Editorial
  1 Scopus citations

• MPTP-Induced nigrostriatal injury in nonhuman primates

  Perlmutter, J. S. & Tabbal, S. D., 2005, Movement Disorders. Elsevier Inc., p. 139-148 10 p.

  Research output: Chapter in Book/Report/Conference proceeding › Chapter › peer-review

  • 4-phenyl-1,2,3,6-tetrahydropyridine 100%
  • Primates 62%
  • Parkinsonian Disorders 61%
  • Wounds and Injuries 32%
  • Dystonia 26%

• MPTP-induced up-regulation of in vivo dopaminergicradioligand-receptor binding in humans

  Perlmutter, J. S., Kilbourn, M. R., Raichle, M. E. & Welch, M. J., Oct 1987, In: Neurology. 37, 10, p. 1575-1579 5 p.

  Research output: Contribution to journal › Article › peer-review

  • Spiperone 100%
  • 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine 91%
  • Up-Regulation 52%
  • MPTP Poisoning 46%
  • spiroperidol receptor 44%
  49 Scopus citations

• MPTP induces dystonia and parkinsonism: Clues to the pathophysiology of dystonia

  Perlmutter, J. S., Tempel, L. W., Black, K. J., Parkinson, D. & Todd, R. D., Nov 1997, In: Neurology. 49, 5, p. 1432-1438 7 p.

  Research output: Contribution to journal › Article › peer-review

  • 4-phenyl-1,2,3,6-tetrahydropyridine 100%
  • Dystonia 78%
  • Parkinsonian Disorders 73%
  • Corpus Striatum 46%
  • Dopamine 40%
  147 Scopus citations

• MRI measures predict progressive supranuclear palsy: Clinically useful?

  Karimi, M. & Perlmutter, J. S., Sep 13 2011, In: Neurology. 77, 11, p. 1028-1029 2 p.

  Research output: Contribution to journal › Editorial
  6 Scopus citations

• Multivariate clustering of progression profiles reveals different depression patterns in prodromal huntington disease

  The PREDICT-HD Investigators and Coordinators of the Huntington Study Group, Nov 2015, In: Neuropsychology. 29, 6, p. 949-960 12 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Huntington Disease 100%
  • Cluster Analysis 80%
  • Depression 59%
  • Disease Progression 15%
  • Neurobehavioral Manifestations 12%
  10 Scopus citations

• Multivariate prediction of motor diagnosis in Huntington's disease: 12 years of PREDICT-HD

  PREDICT-HD Investigators and Coordinators of the Huntington Study Group, Oct 2015, In: Movement Disorders. 30, 12, p. 1664-1672 9 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Cytosine 100%
  • Guanine 99%
  • Adenine 99%
  • Huntington Disease 93%
  • Stroop Test 21%
  27 Scopus citations

• Mutation, sequence analysis, and association studies of α-synuclein in Parkinson's disease

  Parsian, A., Racette, B., Zhang, Z. H., Chakraverty, S., Rundle, M., Goate, A. & Perlmutter, J. S., Dec 1998, In: Neurology. 51, 6, p. 1757-1759 3 p.

  Research output: Contribution to journal › Article › peer-review

  • Synucleins 100%
  • Sequence Analysis 61%
  • Parkinson Disease 55%
  • Mutation 36%
  • Genes 26%
  69 Scopus citations

• Mutational and biochemical analysis of dopamine in dystonia: Evidence for decreased dopamine D₂ receptor inhibition

  Todd, R. D. & Perlmutter, J. S., Jan 1 1998, In: Molecular Neurobiology. 16, 2, p. 135-147 13 p.

  Research output: Contribution to journal › Article › peer-review

  • Dopamine D2 Receptors 100%
  • Dystonia 99%
  • Dopamine 71%
  • Genetic Linkage 15%
  • Putamen 13%
  36 Scopus citations

• Mutations in CIZ1 cause adult onset primary cervical dystonia

  Xiao, J., Uitti, R. J., Zhao, Y., Vemula, S. R., Perlmutter, J. S., Wszolek, Z. K., Maraganore, D. M., Auburger, G., Leube, B., Lehnhoff, K. & Ledoux, M. S., Apr 2012, In: Annals of neurology. 71, 4, p. 458-469 12 p.

  Research output: Contribution to journal › Article › peer-review

  • Primary Cervical Dystonia 100%
  • Dystonic Disorders 42%
  • Mutation 29%
  • Torticollis 27%
  • Exome 24%
  119 Scopus citations

• N-(3-[¹⁸F]fluoropropyl)-spiperone: The preferred ¹⁸F labeled spiperone analog for positron emission tomographic studies of the dopamine receptor

  Welch, M. J., Katzenellenbogen, J. A., Mathias, C. J., Brodack, J. W., Carlson, K. E., Chi, D. Y., Dence, C. S., Kilbourn, M. R., Perlmutter, J. S., Raichle, M. E. & Ter-Pogossian, M. M., 1988, In: International Journal of Radiation Applications and Instrumentation.. 15, 1, p. 83-93,95-97

  Research output: Contribution to journal › Article › peer-review

  • Spiperone 100%
  • Dopamine Receptors 81%
  • Fluorine-18 73%
  • Electrons 57%
  • Ligands 20%
  61 Scopus citations

• N-alkylated analogues of [F-18]benperidol as dopaminergic D-2 receptor ligands

  Moerlein, S. M., Perlmutter, J. S., Bockhorst, J. L., Parkinson, D. & Welch, M. J., Jan 1 1994, In: Journal of Labelled Compounds and Radiopharmaceuticals. 35, p. 462-463 2 p.

  Research output: Contribution to journal › Article › peer-review

• Neural correlates of STN DBS-induced cognitive variability in Parkinson disease

  Campbell, M. C., Karimi, M., Weaver, P. M., Wu, J., Perantie, D. C., Golchin, N. A., Tabbal, S. D., Perlmutter, J. S. & Hershey, T., Nov 2008, In: Neuropsychologia. 46, 13, p. 3162-3169 8 p.

  Research output: Contribution to journal › Article › peer-review

  • Parkinson Disease 100%
  • Gyrus Cinguli 82%
  • Short-Term Memory 74%
  • Prefrontal Cortex 72%
  • Psychological Inhibition 64%
  63 Scopus citations

• Neuroimaging analysis of the dopamine basis for apathetic behaviors in an MPTP-lesioned primate model

  Tian, L. L., Xia, Y., Flores, H. P., Campbell, M. C., Moerlein, S. M. & Perlmutter, J. S., Jul 2 2015, In: PloS one. 10, 7, e0132064.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • 4-phenyl-1,2,3,6-tetrahydropyridine 100%
  • Positron 78%
  • dopamine 67%
  • positron-emission tomography 64%
  • Dopamine 63%
  18 Scopus citations

• Neuroimaging biomarkers for Parkinson disease: Facts and fantasy

  Perlmutter, J. S. & Norris, S. A., Dec 1 2014, In: Annals of neurology. 76, 6, p. 769-783 15 p.

  Research output: Contribution to journal › Article › peer-review

  • Fantasy 100%
  • Neuroimaging 67%
  • Parkinson Disease 62%
  • Biomarkers 48%
  • Parkinsonian Disorders 40%
  29 Scopus citations

• Neuroinflammation and myelin status in Alzheimer's disease, Parkinson's disease, and normal aging brains: A small sample study

  Han, F., Perrin, R. J., Wang, Q., Wang, Y., Perlmutter, J. S., Morris, J. C., Benzinger, T. L. S. & Xu, J., 2019, In: Parkinson's Disease. 2019, 7975407.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Myelin Sheath 100%
  • White Matter 88%
  • Parkinson Disease 81%
  • Alzheimer Disease 75%
  • Microglia 59%
  14 Scopus citations

• Neurologist-associated reduction in PD-related hospitalizations and health care expenditures

  Willis, A. W., Schootman, M., Pollard, R., Kung, N., Evanoff, B. A., Perlmutter, J. S. & Racette, B. A., Oct 23 2012, In: Neurology. 79, 17, p. 1774-1780 7 p.

  Research output: Contribution to journal › Article › peer-review

  • Neurologists 100%
  • Health Expenditures 91%
  • Parkinson Disease 75%
  • Hospitalization 66%
  • Delivery of Health Care 54%
  62 Scopus citations

• Neurologist care in Parkinson disease: A utilization, outcomes, and survival study

  Willis, A. W., Schootman, M., Evanoff, B. A., Perlmutter, J. S. & Racette, B. A., Aug 30 2011, In: Neurology. 77, 9, p. 851-857 7 p.

  Research output: Contribution to journal › Article › peer-review

  • Neurologists 100%
  • Parkinson Disease 75%
  • Health Care Outcome Assessment 58%
  • Survival 49%
  • Confidence Intervals 26%
  152 Scopus citations

• Neuropathology of blepharospasm

  Fagan, M., Scorr, L., Bernhardt, D., Hess, E. J., Perlmutter, J. S., Pardo, C. A. & Jinnah, H. A., Dec 2021, In: Experimental Neurology. 346, 113855.

  Research output: Contribution to journal › Article › peer-review

  • Blepharospasm 100%
  • Purkinje Cells 77%
  • Neuropathology 76%
  • Torpedo 32%
  • Torticollis 15%

• New insights into the pathophysiology of Parkinson's disease: the challenge of positron emission tomography

  Perlmutter, J. S., 1988, In: Trends in Neurosciences. 11, 5, p. 203-208 6 p.

  Research output: Contribution to journal › Article › peer-review

  • Positron-Emission Tomography 100%
  • Parkinson Disease 89%
  • Neurotransmitter Receptor 65%
  • Disclosure 59%
  • Research Subjects 53%
  20 Scopus citations

• New measures to capture end of life concerns in Huntington disease: Meaning and Purpose and Concern with Death and Dying from HDQLIFE (a patient-reported outcomes measurement system)

  Carlozzi, N. E., Downing, N. R., McCormack, M. K., Schilling, S. G., Perlmutter, J. S., Hahn, E. A., Lai, J. S., Frank, S., Quaid, K. A., Paulsen, J. S., Cella, D., Goodnight, S. M., Miner, J. A. & Nance, M. A., Oct 1 2016, In: Quality of Life Research. 25, 10, p. 2403-2415 13 p.

  Research output: Contribution to journal › Article › peer-review

  • Huntington Disease 100%
  • Patient Reported Outcome Measures 99%
  • dying 94%
  • death 65%
  • Psychometrics 16%
  20 Scopus citations

• New techniques in neuroimaging: When are pretty pictures clinically useful?

  Perlmutter, J. S., 1993, In: Current opinion in neurology. 6, 6, p. 889-890 2 p.

  Research output: Contribution to journal › Comment/debate
  1 Scopus citations

• No differential regulation of dopamine transporter (DAT) and vesicular monoamine transporter 2 (VMAT2) binding in a primate model of Parkinson disease

  Tian, L. L., Karimi, M., Loftin, S. K., Brown, C. A., Xia, H. C., Xu, J. B., Mach, R. H. & Perlmutter, J. S., Feb 16 2012, In: PloS one. 7, 2, e31439.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Vesicular Monoamine Transport Proteins 100%
  • Parkinson disease 89%
  • monoamines 82%
  • Dopamine Plasma Membrane Transport Proteins 81%
  • Monoamine 76%
  25 Scopus citations

• No genetic association between attention-deficit/hyperactivity disorder (ADHD) and Parkinson’s disease in nine ADHD candidate SNPs

  International Parkinson Disease Genomics Consortium members, Jun 1 2017, In: ADHD Attention Deficit and Hyperactivity Disorders. 9, 2, p. 121-127 7 p.

  Research output: Contribution to journal › Article › peer-review

  • ADHD 100%
  • Attention Deficit Disorder with Hyperactivity 96%
  • Single Nucleotide Polymorphism 79%
  • Parkinson Disease 79%
  • candidacy 71%
  9 Scopus citations

• Non-motor phenotypic subgroups in adult-onset idiopathic, isolated, focal cervical dystonia

  Wadon, M. E., Bailey, G. A., Yilmaz, Z., Hubbard, E., AlSaeed, M., Robinson, A., McLauchlan, D., Barbano, R. L., Marsh, L., Factor, S. A., Fox, S. H., Adler, C. H., Rodriguez, R. L., Comella, C. L., Reich, S. G., Severt, W. L., Goetz, C. G., Perlmutter, J. S., Jinnah, H. A., Harding, K. E. & 2 others, Sandor, C. & Peall, K. J., Aug 2021, In: Brain and Behavior. 11, 8, e2292.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Dystonic Disorders 100%
  • Torticollis 98%
  • Catastrophization 74%
  • Dystonia 64%
  • Sleep 57%

• Non-steady-state measurement of in vivo radioligand binding with positron emission tomography: Specificity analysis and comparison with in vitro binding

  Perlmutter, J. S., Moerlein, S. M., Hwang, D. R. & Todd, R. D., 1991, In: Journal of Neuroscience. 11, 5, p. 1381-1389 9 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Positron-Emission Tomography 100%
  • Ketanserin 60%
  • eticlopride 50%
  • In Vitro Techniques 47%
  • Corpus Striatum 44%
  28 Scopus citations

• Non-steady-state measurement of in vivo receptor binding with positron emission tomography: 'Dose-response' analysis

  Perlmutter, J. S., Kilbourn, M. R., Welch, M. J. & Raichle, M. E., 1989, In: Journal of Neuroscience. 9, 7, p. 2344-2352 9 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  19 Scopus citations

• Normal platelet mitochondrial complex I activity in Huntington's Disease

  Powers, W. J., Haas, R. H., Le, T., Videen, T. O., Hershey, T., McGee-Minnich, L. & Perlmutter, J. S., Jul 2007, In: Neurobiology of Disease. 27, 1, p. 99-101 3 p.

  Research output: Contribution to journal › Article › peer-review

  • Huntington Disease 100%
  • Blood Platelets 70%
  • Corpus Striatum 17%
  • Genes 7%
  25 Scopus citations

• Novel haplotypes in 17q21 are associated with progressive supranuclear palsy

  Pastor, P., Ezquerra, M., Perez, J. C., Chakraverty, S., Norton, J., Racette, B. A., McKeel, D., Perlmutter, J. S., Tolosa, E. & Goate, A. M., Aug 2004, In: Annals of neurology. 56, 2, p. 249-258 10 p.

  Research output: Contribution to journal › Article › peer-review

  • Progressive Supranuclear Palsy 100%
  • Haplotypes 70%
  • Single Nucleotide Polymorphism 20%
  • Neurofibrillary Tangles 15%
  • Parkinsonian Disorders 13%
  55 Scopus citations

• Novel human pathological mutations. Gene symbol: THAP1. Disease: dystonia 6.

  Xiao, J., Zhao, Y., Bastian, R. W., Perlmutter, J. S., Racette, B. A., Tabbal, S. D., Karimi, M., Paniell, R., Blitzer, A., Batish, S. D., Wszolek, Z. K., Uitti, R. J., Van Gerpen, J. A., Hedera, P., Simon, D. K., Tarsy, D., Truong, D. D., Frei, K. P., Pfeiffer, R. F., Gong, S. & 1 others, LeDoux, M. S., Apr 2010, In: Human genetics. 127, 4, p. 469 1 p.

  Research output: Contribution to journal › Article › peer-review

  3 Scopus citations