Personal profile
Research interests
Our group works on the pathophysiology, etiology and treatment of movement disorders including Parkinson disease, dystonia, Tourette's syndrome, essential tremor, and Huntington's disease. We also investigate basal ganglia physiology and pharmacology.
Clinical interests
Parkinson's disease, Huntington's disease, Tourette syndrome, dystonia, hyperkinetic disorders, essential tremor and other movement disorders, imaging research using PET and MR, clinical drug trials
Available to Mentor:
- PhD Students
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Collaborations and top research areas from the last five years
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Brain network pathophysiology in dystonia
Peterson, D. A., Kim, M., Chen, R., Eidelberg, D., Gallea, C., Horn, A. G., Lehericy, S., McIntosh, A. R., Perlmutter, J. S., Sadnicka, A., Sanger, T. D., Santarnecchi, E., Starr, P. A., Teller, J. K., Hallett, M. & Simonyan, K., 2026, In: Dystonia. 4, 15446.Research output: Contribution to journal › Review article › peer-review
Open Access -
Design, synthesis, and characterization of F-18 sigma-1 receptor radiotracers for Alzheimer disease
Jiang, H., Jadhav, S. B., Soda, A. K., Zhou, W., Chen, H., Xu, S., Qiu, L., Huang, T., Xing, Z., Zhao, L., Lee, J. J., Ni, R., Wong, D. F., Peng, G., Perlmutter, J. S., Benzinger, T. L. S. & Tu, Z., Apr 5 2026, In: European Journal of Medicinal Chemistry. 307, 118647.Research output: Contribution to journal › Article › peer-review
Open Access -
Differentiating effects of levodopa and subthalamic nucleus deep brain stimulation on motor features in Parkinson disease
Lee, T. A., Ramesh, D., Ushe, M., Norris, S. A., Tabbal, S. D., Perlmutter, J. S. & Younce, J. R., Jan 1 2026, In: Clinical Parkinsonism and Related Disorders. 14, 100417.Research output: Contribution to journal › Article › peer-review
Open Access -
Discovery and in vivo evaluation of a fluorine-18 pro-drug tracer for imaging sphingosine-1-phosphate receptor 2 in the brain
Qiu, L., Zhou, W., Chen, H., Jiang, H., Lang, J., Xing, Z., Heady, M., Gropler, R. J., Guglielmetti, C., Perlmutter, J. S. & Tu, Z., Mar 2026, In: Bioorganic and Medicinal Chemistry. 134, 118536.Research output: Contribution to journal › Article › peer-review
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Evaluation of [11C]CS1P1 in Healthy Young and Older Adults
Friedrichsen, K. A., Judge, B. A., Jones, L. A., Rajamanickam, J., Qiu, L., Soda, A. K., Rahmani, F., Benzinger, G. R., King, C. R., Chaney, A. M., Nickels, M. L., Gropler, R. J., Raji, C. A., White, R. L., Perlmutter, J. S., Laforest, R., An, H., Tu, Z., Benzinger, T. L. S. & Brier, M. R., Jan 1 2026, In: American Journal of Neuroradiology. 47, 1, p. 175-183 9 p.Research output: Contribution to journal › Article › peer-review
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