Joe Jez

2025

Expanding the Landscape of Dual Action Antifolate Antibacterials through 2,4-Diamino-1,6-dihydro-1,3,5-triazines

Georgiades, J. D., Berkovich, D. A., McKee, S. R., Smith, A. R., Sankaran, B., Flentie, K. N., Castañeda, C. H., Grohmann, D. G., Rohatgi, R., Lasky, C., Mason, T. A., Champine, J. E., Miller, P. A., Möllmann, U., Moraski, G. C., Franzblau, S. G., Miller, M. J., Stallings, C. L., Jez, J. M. & Hathaway, B. A. & 1 others, Wencewicz, T. A., Mar 14 2025, In: ACS Infectious Diseases. 11, 3, p. 689-702 14 p.

Research output: Contribution to journal › Article › peer-review

2024

4-Aldrithiol-based photometric assay for detection of methylthioalkylmalate synthase activity

Kitainda, V. & Jez, J., Jan 2024, Siderophore and Related Natural Products Biosynthesis. Wencewicz, T. (ed.). Academic Press Inc., p. 229-245 17 p. (Methods in Enzymology; vol. 702).

Research output: Chapter in Book/Report/Conference proceeding › Chapter › peer-review

1 Scopus citations

C₄ grasses employ distinct strategies to acclimate rubisco activase to heat stress

Stainbrook, S. C., Aubuchon, L. N., Chen, A., Johnson, E., Si, A., Walton, L., Ahrendt, A. J., Strenkert, D. & Jez, J. M., Oct 2024, In: Bioscience Reports. 44, 10, BSR20240353.

Research output: Contribution to journal › Article › peer-review

Open Access

Fidelity in plant hormone modifications catalyzed by Arabidopsis GH3 acyl acid amido synthetases

Holland, C. K. & Jez, J. M., Jul 2024, In: Journal of Biological Chemistry. 300, 7, 107421.

Research output: Contribution to journal › Article › peer-review

Open Access

Investigating the biosynthesis and roles of the auxin phenylacetic acid during Pseudomonas syringae-Arabidopsis thaliana pathogenesis

Lee, C. Y., Harper, C. P., Lee, S. G., Qi, Y., Clay, T., Aoi, Y., Jez, J. M., Kasahara, H., Blodgett, J. A. V. & Kunkel, B. N., 2024, In: Frontiers in Plant Science. 15, 1408833.

Research output: Contribution to journal › Article › peer-review

Open Access

Kinetic and catalytic mechanisms of the methionine-derived glucosinolate biosynthesis enzyme methylthioalkylmalate synthase

Kitainda, V. & Jez, J. M., Nov 2024, In: Journal of Biological Chemistry. 300, 11, 107814.

Research output: Contribution to journal › Article › peer-review

Open Access

Structure-function analysis of plant G-protein regulatory mechanisms identifies key Gα-RGS protein interactions

Torres-Rodriguez, M. D., Lee, S. G., Roy Choudhury, S., Paul, R., Selvam, B., Shukla, D., Jez, J. M. & Pandey, S., May 2024, In: Journal of Biological Chemistry. 300, 5, 107252.

Research output: Contribution to journal › Article › peer-review

Open Access

1 Scopus citations

2023

A tale of two switches: Redox regulation of adenosine-5′-phosphosulfate kinase in humans and plants

Morris, J. S. & Jez, J. M., Jul 6 2023, In: Structure. 31, 7, p. 757-759 3 p.

Research output: Contribution to journal › Comment/debate

Open Access

Preface

Jez, J., Jan 2023, Biochemical Pathways and Environmental Responses in Plants: Part B. Jez, J. (ed.). Academic Press Inc., p. xvii-xviii (Methods in Enzymology; vol. 680).

Research output: Chapter in Book/Report/Conference proceeding › Foreword/postscript

Preface

Jez, J., Jan 2023, Biochemical Pathways and Environmental Responses in Plants: Part C. Jez, J. (ed.). Academic Press Inc., p. xv-xvi (Methods in Enzymology; vol. 683).

Research output: Chapter in Book/Report/Conference proceeding › Foreword/postscript

2022

Biochemical and clinical studies of putative allergens to assess what distinguishes them from other non-allergenic proteins in the same family

Glenn, K. C., Silvanovich, A., Lee, S. G., Allen, A., Park, S., Dunn, S. E., Kessenich, C., Meng, C., Vicini, J. L. & Jez, J. M., Oct 2022, In: Transgenic Research. 31, 4-5, p. 507-524 18 p.

Research output: Contribution to journal › Article › peer-review

Open Access

1 Scopus citations

Chemical inhibition of the auxin inactivation pathway uncovers the roles of metabolic turnover in auxin homeostasis

Fukui, K., Arai, K., Tanaka, Y., Aoi, Y., Kukshal, V., Jez, J. M., Kubes, M. F., Napier, R., Zhao, Y., Kasahara, H. & Hayashi, K. I., Aug 9 2022, In: Proceedings of the National Academy of Sciences of the United States of America. 119, 32, e2206869119.

Research output: Contribution to journal › Article › peer-review

Open Access

25 Scopus citations

Chronologically modified androgen receptor in recurrent castration-resistant prostate cancer and its therapeutic targeting

Sawant, M., Mahajan, K., Renganathan, A., Weimholt, C., Luo, J., Kukshal, V., Jez, J. M., Jeon, M. S., Zhang, B., Li, T., Fang, B., Luo, Y., Lawrence, N. J., Lawrence, H. R., Feng, F. Y. & Mahajan, N. P., Jun 15 2022, In: Science translational medicine. 14, 649, eabg4132.

Research output: Contribution to journal › Article › peer-review

Open Access

18 Scopus citations

Connecting primary and specialized metabolism: Amino acid conjugation of phytohormones by GRETCHEN HAGEN 3 (GH3) acyl acid amido synthetases

Jez, J. M., Apr 2022, In: Current Opinion in Plant Biology. 66, 102194.

Research output: Contribution to journal › Review article › peer-review

Open Access

24 Scopus citations

Distribution and the evolutionary history of G-protein components in plant and algal lineages

Mohanasundaram, B., Dodds, A., Kukshal, V., Jez, J. M. & Pandey, S., Jul 2022, In: Plant Physiology. 189, 3, p. 1519-1535 17 p.

Research output: Contribution to journal › Article › peer-review

Open Access

12 Scopus citations

Enzymatic and structural characterization of HAD5, an essential phosphomannomutase of malaria-causing parasites

Frasse, P. M., Miller, J. J., Polino, A. J., Soleimani, E., Zhu, J. S., Jakeman, D. L., Jez, J. M., Goldberg, D. E. & Odom John, A. R., Feb 1 2022, In: Journal of Biological Chemistry. 298, 2, 101550.

Research output: Contribution to journal › Article › peer-review

Open Access

4 Scopus citations

Orthology-based analysis helps map evolutionary diversification and predict substrate class use of BAHD acyltransferases

Kruse, L. H., Weigle, A. T., Irfan, M., Martínez-Gómez, J., Chobirko, J. D., Schaffer, J. E., Bennett, A. A., Specht, C. D., Jez, J. M., Shukla, D. & Moghe, G. D., Sep 2022, In: Plant Journal. 111, 5, p. 1453-1468 16 p.

Research output: Contribution to journal › Article › peer-review

23 Scopus citations

Point mutations that boost aromatic amino acid production and CO₂ assimilation in plants

Yokoyama, R., de Oliveira, M. V. V., Takeda-Kimura, Y., Ishihara, H., Alseekh, S., Arrivault, S., Kukshal, V., Jez, J. M., Stitt, M., Fernie, A. R. & Maeda, H. A., Jun 2022, In: Science Advances. 8, 23, eabo3416.

Research output: Contribution to journal › Article › peer-review

Open Access

16 Scopus citations

Protein Domains: Structure, Function, and Methods

Korasick, D. A. & Jez, J. M., Jan 1 2022, Encyclopedia of Cell Biology: Volume 1-6, Second Edition. Elsevier, Vol. 1. p. 106-114 9 p.

Research output: Chapter in Book/Report/Conference proceeding › Chapter › peer-review

Two independently evolved natural mutations additively deregulate TyrA enzymes and boost tyrosine production in planta

Lopez-Nieves, S., El-Azaz, J., Men, Y., Holland, C. K., Feng, T., Brockington, S. F., Jez, J. M. & Maeda, H. A., Feb 2022, In: Plant Journal. 109, 4, p. 844-855 12 p.

Research output: Contribution to journal › Article › peer-review

Open Access

10 Scopus citations

2021

A natural single-nucleotide polymorphism variant in sulfite reductase influences sulfur assimilation in maize

Jiang, L., Wang, Y., Xia, A., Wang, Q., Zhang, X., Jez, J. M., Li, Z., Tan, W. & He, Y., Oct 2021, In: New Phytologist. 232, 2, p. 692-704 13 p.

Research output: Contribution to journal › Article › peer-review

3 Scopus citations

Beyond X-rays: An overview of emerging structural biology methods

Schaffer, J. E., Kukshal, V., Miller, J. J., Kitainda, V. & Jez, J. M., May 2021, In: Emerging Topics in Life Sciences. 5, 2, p. 221-230 10 p.

Research output: Contribution to journal › Review article › peer-review

10 Scopus citations

Encyclopedia of biological chemistry: Third edition

Jez, J., Jul 29 2021, Elsevier. 4822 p.

Research output: Book/Report › Book › peer-review

1 Scopus citations

Introduction to emerging technologies in plant science

Topp, C. N. & Jez, J. M., May 2021, In: Emerging Topics in Life Sciences. 5, 2, p. 177-178 2 p.

Research output: Contribution to journal › Review article › peer-review

Open Access

2 Scopus citations

Introduction to the encyclopedia of biological chemistry

Jez, J., Cooper, A. J. L., Blankenship, B., Chapman, K., Allewell, N., Zaher, H., Maresca, T. J. & Pandey, S., Jul 29 2021, Encyclopedia of Biological Chemistry: Third Edition. Elsevier, Vol. 1. p. 1-2 2 p.

Research output: Chapter in Book/Report/Conference proceeding › Foreword/postscript

Protecting P-type plasma membrane H⁺-ATPases from ROS

Stainbrook, S. C. & Jez, J. M., Apr 2021, In: Biochemical Journal. 478, 8, p. 1511-1513 3 p.

Research output: Contribution to journal › Review article › peer-review

1 Scopus citations

Structural studies of aliphatic glucosinolate chain-elongation enzymes

Kitainda, V. & Jez, J. M., Sep 2021, In: Antioxidants. 10, 9, 1500.

Research output: Contribution to journal › Review article › peer-review

Open Access

18 Scopus citations

Structure-guided microbial targeting of antistaphylococcal prodrugs

Miller, J. J., Shah, I. T., Hatten, J., Barekatain, Y., Mueller, E. A., Moustafa, A. M., Edwards, R. L., Dowd, C. S., Planet, P. J., Muller, F. L., Jez, J. M. & John, A. R. O., Jul 2021, In: eLife. 10, e66657.

Research output: Contribution to journal › Article › peer-review

Open Access

13 Scopus citations

2020

Investigating the reaction and substrate preference of indole-3-acetaldehyde dehydrogenase from the plant pathogen pseudomonas syringae PtoDC3000

Zhang, K., Lee, J. S., Liu, R., Chan, Z. T., Dawson, T. J., de Togni, E. S., Edwards, C. T., Eng, I. K., Gao, A. R., Goicouria, L. A., Hall, E. M., Hu, K. A., Huang, K., Kizhner, A., Kodama, K. C., Lin, A. Z., Liu, J. Y., Lu, A. Y., Peng, O. W. & Ryu, E. P. & 13 others, Shi, S., Sorkin, M. L., Walker, P. L., Wang, G. J., Xu, M. C., Yang, R. S., Cascella, B., Cruz, W., Holland, C. K., McClerkin, S. A., Kunkel, B. N., Lee, S. G. & Jez, J. M., Dec 2020, In: Bioscience Reports. 40, 12, BSR20202959.

Research output: Contribution to journal › Article › peer-review

Open Access

4 Scopus citations

Natural product biosynthesis: What’s next? An introduction to the JBC Reviews Thematic Series

Nair, S. K. & Jez, J. M., Jan 10 2020, In: Journal of Biological Chemistry. 295, 2, p. 335-336 2 p.

Research output: Contribution to journal › Review article › peer-review

Open Access

9 Scopus citations

Overexpression of ATP sulfurylase improves the sulfur amino acid content, enhances the accumulation of Bowman–Birk protease inhibitor and suppresses the accumulation of the β-subunit of β-conglycinin in soybean seeds

Kim, W. S., Sun-Hyung, J., Oehrle, N. W., Jez, J. M. & Krishnan, H. B., Dec 1 2020, In: Scientific reports. 10, 1, 14989.

Research output: Contribution to journal › Article › peer-review

Open Access

19 Scopus citations

Plants in the real world: An introduction to the JBC reviews thematic series

Jez, J. M., Nov 6 2020, In: Journal of Biological Chemistry. 295, 45, p. 15376-15377 2 p.

Research output: Contribution to journal › Article › peer-review

Open Access

1 Scopus citations

Potent, specific MEPicides for treatment of zoonotic staphylococci

Edwards, R. L., Heueck, I., Lee, S. G., Shah, I. T., Miller, J. J., Jezewski, A. J., Mikati, M. O., Wang, X., Brothers, R. C., Heidel, K. M., Osbourn, D. M., Burnham, C. A. D., Alvarez, S., Fritz, S. A., Dowd, C. S., Jez, J. M. & Odom John, A. R., Jun 2020, In: PLoS pathogens. 16, 6, e1007806.

Research output: Contribution to journal › Article › peer-review

Open Access

12 Scopus citations

Structural and biochemical analysis of phosphoethanolamine methyltransferase from the pine wilt nematode Bursaphelenchus xylophilus

Lee, S. G., Chung, M. S., DeMarsilis, A. J., Holland, C. K., Jaswaney, R. V., Jiang, C., Kroboth, J. H. P., Kulshrestha, K., Marcelo, R. Z. W., Meyyappa, V. M., Nelson, G. B., Patel, J. K., Petronio, A. J., Powers, S. K., Qin, P. R., Ramachandran, M., Rayapati, D., Rincon, J. A., Rocha, A. & Ferreira, J. G. R. N. & 9 others, Steinbrecher, M. K., Yao, K., Zhang, E. J., Zou, A. J., Gang, M., Sparks, M., Cascella, B., Cruz, W. & Jez, J. M., Jul 2020, In: Molecular and Biochemical Parasitology. 238, 111291.

Research output: Contribution to journal › Article › peer-review

Open Access

3 Scopus citations

The plant pathogen enzyme AldC is a long-chain aliphatic aldehyde dehydrogenase

Lee, S. G., Harline, K., Abar, O., Akadri, S. O., Bastian, A. G., Chen, H. Y. S., Duan, M., Focht, C. M., Groziak, A. R., Kao, J., Kottapalli, J. S., Leong, M. C., Lin, J. J., Liu, R., Luo, J. E., Meyer, C. M., Mo, A. F., Pahng, S. H., Penna, V. & Raciti, C. D. & 10 others, Srinath, A., Sudhakar, S., Tang, J. D., Cox, B. R., Holland, C. K., Cascella, B., Cruz, W., McClerkin, S. A., Kunkel, B. N. & Jez, J. M., Oct 2 2020, In: Journal of Biological Chemistry. 295, 40, p. 13914-13926 13 p.

Research output: Contribution to journal › Article › peer-review

Open Access

5 Scopus citations

2019

Bifunctional Substrate Activation via an Arginine Residue Drives Catalysis in Chalcone Isomerases

Burke, J. R., La Clair, J. J., Philippe, R. N., Pabis, A., Corbella, M., Jez, J. M., Cortina, G. A., Kaltenbach, M., Bowman, M. E., Louie, G. V., Woods, K. B., Nelson, A. T., Tawfik, D. S., Kamerlin, S. C. L. & Noel, J. P., Sep 6 2019, In: ACS Catalysis. 9, 9, p. 8388-8396 9 p.

Research output: Contribution to journal › Article › peer-review

Open Access

13 Scopus citations

Brassicaceae-specific Gretchen Hagen 3 acyl acid amido synthetases conjugate amino acids to chorismate, a precursor of aromatic amino acids and salicylic acid

Holland, C. K., Westfall, C. S., Schaffer, J. E., De Santiago, A., Zubieta, C., Alvarez, S. & Jez, J. M., Nov 8 2019, In: Journal of Biological Chemistry. 294, 45, p. 16855-16864 10 p.

Research output: Contribution to journal › Article › peer-review

Open Access

16 Scopus citations

Molecular basis for branched steviol glucoside biosynthesis

Lee, S. G., Salomon, E., Yu, O. & Jez, J. M., 2019, In: Proceedings of the National Academy of Sciences of the United States of America. 116, 26, p. 13131-13136 6 p.

Research output: Contribution to journal › Article › peer-review

Open Access

53 Scopus citations

Molecular basis of the evolution of methylthioalkylmalate synthase and the diversity of methionine-derived glucosinolates

Kumar, R., Lee, S. G., Augustine, R., Reichelt, M., Vassão, D. G., Palavalli, M. H., Allen, A., Gershenzon, J., Jez, J. M. & Bisht, N. C., Jul 2019, In: Plant Cell. 31, 7, p. 1633-1647 15 p.

Research output: Contribution to journal › Article › peer-review

Open Access

35 Scopus citations

Nucleo-cytoplasmic Partitioning of ARF Proteins Controls Auxin Responses in Arabidopsis thaliana

Powers, S. K., Holehouse, A. S., Korasick, D. A., Schreiber, K. H., Clark, N. M., Jing, H., Emenecker, R., Han, S., Tycksen, E., Hwang, I., Sozzani, R., Jez, J. M., Pappu, R. V. & Strader, L. C., Oct 3 2019, In: Molecular cell. 76, 1, p. 177-190.e5

Research output: Contribution to journal › Article › peer-review

Open Access

163 Scopus citations

Plant nitrilase: A new job for an old enzyme

Jez, J. M., Apr 10 2019, In: Biochemical Journal. 476, 7, p. 1105-1107 3 p.

Research output: Contribution to journal › Review article › peer-review

4 Scopus citations

Structural biology of plant sulfur metabolism: From sulfate to glutathione

Jez, J. M., Aug 19 2019, In: Journal of Experimental Botany. 70, 16, p. 4089-4103 15 p., erz094.

Research output: Contribution to journal › Review article › peer-review

49 Scopus citations

2018

A multisubstrate reductase from Plantago major: structure-function in the short chain reductase superfamily

Fellows, R., Russo, C. M., Silva, C. S., Lee, S. G., Jez, J. M., Chisholm, J. D., Zubieta, C. & Nanao, M. H., Dec 1 2018, In: Scientific reports. 8, 1, 14796.

Research output: Contribution to journal › Article › peer-review

Open Access

12 Scopus citations

Antimalarial agents against both sexual and asexual parasites stages: structure-activity relationships and biological studies of the Malaria Box compound 1-[5-(4-bromo-2-chlorophenyl)furan-2-yl]-N-[(piperidin-4-yl)methyl]methanamine (MMV019918) and analogues

Vallone, A., D'Alessandro, S., Brogi, S., Brindisi, M., Chemi, G., Alfano, G., Lamponi, S., Lee, S. G., Jez, J. M., Koolen, K. J. M., Dechering, K. J., Saponara, S., Fusi, F., Gorelli, B., Taramelli, D., Parapini, S., Caldelari, R., Campiani, G., Gemma, S. & Butini, S., Apr 25 2018, In: European Journal of Medicinal Chemistry. 150, p. 698-718 21 p.

Research output: Contribution to journal › Article › peer-review

Open Access

32 Scopus citations

Arabidopsis: the original plant chassis organism

Holland, C. K. & Jez, J. M., Oct 1 2018, In: Plant Cell Reports. 37, 10, p. 1359-1366 8 p.

Research output: Contribution to journal › Review article › peer-review

14 Scopus citations

Arabidopsis thaliana GH3.15 acyl acid amido synthetase has a highly specific substrate preference for the auxin precursor indole-3-butyric acid

Sherp, A. M., Westfall, C. S., Alvarez, S. & Jez, J. M., Mar 23 2018, In: Journal of Biological Chemistry. 293, 12, p. 4277-4288 12 p.

Research output: Contribution to journal › Article › peer-review

Open Access

36 Scopus citations

Beyond the Teaching Assistantship: CURE Leadership as a Training Platform for Future Faculty

Cascella, B. & Jez, J. M., Jan 9 2018, In: Journal of Chemical Education. 95, 1, p. 3-6 4 p.

Research output: Contribution to journal › Review article › peer-review

Open Access

21 Scopus citations

Impact of overexpression of cytosolic isoform of O-acetylserine sulfhydrylase on soybean nodulation and nodule metabolome

Krishnan, H. B., Song, B., Oehrle, N. W., Cameron, J. C. & Jez, J. M., Dec 1 2018, In: Scientific reports. 8, 1, 2367.

Research output: Contribution to journal › Article › peer-review

Open Access

12 Scopus citations

Improving societies’ harassment policies

Anbar, A., Elgin, S., Jez, J., O’Dowd, D., Shapiro, B. & Zaman, M., Sep 7 2018, In: Science. 361, 6406, p. 984-985 2 p.

Research output: Contribution to journal › Letter › peer-review

Indole-3-acetaldehyde dehydrogenase-dependent auxin synthesis contributes to virulence of Pseudomonas syringae strain DC3000

McClerklin, S. A., Lee, S. G., Harper, C. P., Nwumeh, R., Jez, J. M. & Kunkel, B. N., Jan 2018, In: PLoS pathogens. 14, 1, e1006811.

Research output: Contribution to journal › Article › peer-review

Open Access

122 Scopus citations

Joe Jez

Research output

Search results