Joan Riley

Associate Professor of Obstetrics and Gynecology, Associate Professor of Medicine, Associate Professor of Pediatrics

    • 3395 Citations

    Research output per year

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    Personal profile

    Research interests

    Pre-eclampsia is a pregnancy-associated complication that affects between 2-10% of all pregnancies and is the leading cause of perinatal morbidity and mortality. The cause of pre-eclampsia is currently unknown however it is thought that placental injury associated with this disorder may be the result of recurrent ischemia and reperfusion (hypoxia and reoxygenation). Toll-like receptors (TLRs) are part of the host innate immune response that are activated by cell stress or cell damage in addition to pathogen-associated molecular patterns (PAMPs). It is documented that certain TLRs are involved in ischemia-reperfusion induced injury in other organ systems such as the heart and liver. We wish to understand the role of TLRs in ischemia-reperfusion induced placental injury associated with pre-eclampsia and identify mechanisms by which TLRs may mediate their effects.

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    Research Output

    • 3395 Citations
    • 24 Article
    • 6 Review article
  • 5 Scopus citations

    Membrane Potential Determined by Flow Cytometry Predicts Fertilizing Ability of Human Sperm

    Molina, L. C. P., Gunderson, S., Riley, J., Lybaert, P., Borrego-Alvarez, A., Jungheim, E. S. & Santi, C. M., Jan 21 2020, In : Frontiers in Cell and Developmental Biology. 7, 387.

    Research output: Contribution to journalArticle

    Open Access
  • 2 Scopus citations

    Recent trends in embryo disposition choices made by patients following in vitro fertilization

    Alexander, V. M., Riley, J. K. & Jungheim, E. S., 2020, (Accepted/In press) In : Journal of Assisted Reproduction and Genetics.

    Research output: Contribution to journalArticle

  • Antenatal pomegranate juice rescues hypoxia-induced fetal growth restriction in pregnant mice while reducing placental cell stress and apoptosis

    Chen, B., Longtine, M. S., Riley, J. K. & Nelson, D. M., Jun 2018, In : Placenta. 66, p. 1-7 7 p.

    Research output: Contribution to journalArticle

  • 5 Scopus citations
  • 13 Scopus citations