Joan Riley

Associate Professor of Obstetrics and Gynecology, Associate Professor of Medicine, Associate Professor of Pediatrics

3395 Citations

Research output per year

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Personal profile

Research interests

Pre-eclampsia is a pregnancy-associated complication that affects between 2-10% of all pregnancies and is the leading cause of perinatal morbidity and mortality. The cause of pre-eclampsia is currently unknown however it is thought that placental injury associated with this disorder may be the result of recurrent ischemia and reperfusion (hypoxia and reoxygenation). Toll-like receptors (TLRs) are part of the host innate immune response that are activated by cell stress or cell damage in addition to pathogen-associated molecular patterns (PAMPs). It is documented that certain TLRs are involved in ischemia-reperfusion induced injury in other organ systems such as the heart and liver. We wish to understand the role of TLRs in ischemia-reperfusion induced placental injury associated with pre-eclampsia and identify mechanisms by which TLRs may mediate their effects.

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Research Output

3395 Citations
24 Article
6 Review article

Association of the eukaryotic vaginal virome with prophylactic antibiotic exposure and reproductive outcomes in a subfertile population undergoing in vitro fertilisation: a prospective exploratory study

Eskew, A. M., Stout, M. J., Bedrick, B. S., Riley, J. K., Omurtag, K. R., Jimenez, P. T., Odem, R. R., Ratts, V. S., Keller, S. L., Jungheim, E. S. & Wylie, K. M., Jan 1 2020, In : BJOG: An International Journal of Obstetrics and Gynaecology. 127, 2, p. 208-216 9 p.

Research output: Contribution to journal › Article

5 Scopus citations

Membrane Potential Determined by Flow Cytometry Predicts Fertilizing Ability of Human Sperm

Molina, L. C. P., Gunderson, S., Riley, J., Lybaert, P., Borrego-Alvarez, A., Jungheim, E. S. & Santi, C. M., Jan 21 2020, In : Frontiers in Cell and Developmental Biology. 7, 387.

Research output: Contribution to journal › Article

Open Access

2 Scopus citations

Recent trends in embryo disposition choices made by patients following in vitro fertilization

Alexander, V. M., Riley, J. K. & Jungheim, E. S., 2020, (Accepted/In press) In : Journal of Assisted Reproduction and Genetics.

Research output: Contribution to journal › Article

Antenatal pomegranate juice rescues hypoxia-induced fetal growth restriction in pregnant mice while reducing placental cell stress and apoptosis

Chen, B., Longtine, M. S., Riley, J. K. & Nelson, D. M., Jun 2018, In : Placenta. 66, p. 1-7 7 p.

Research output: Contribution to journal › Article

5 Scopus citations

Is there a role for diet in ameliorating the reproductive sequelae associated with chronic low-grade inflammation in polycystic ovary syndrome and obesity?

Riley, J. K. & Jungheim, E. S., Sep 1 2016, In : Fertility and Sterility. 106, 3, p. 520-527 8 p.

Research output: Contribution to journal › Review article

13 Scopus citations