Jiye Cheng

2024

Deficiency of IL-22–binding protein enhances the ability of the gut microbiota to protect against enteric pathogens

Fachi, J. L., Di Luccia, B., Gilfillan, S., Chang, H. W., Song, C., Cheng, J., Cella, M., Vinolo, M. A., Gordon, J. I. & Colonna, M., May 7 2024, In: Proceedings of the National Academy of Sciences of the United States of America. 121, 19, e2321836121.

Research output: Contribution to journal › Article › peer-review

Open Access

1 Scopus citations

Prevotella copri and microbiota members mediate the beneficial effects of a therapeutic food for malnutrition

Chang, H. W., Lee, E. M., Wang, Y., Zhou, C., Pruss, K. M., Henrissat, S., Chen, R. Y., Kao, C., Hibberd, M. C., Lynn, H. M., Webber, D. M., Crane, M., Cheng, J., Rodionov, D. A., Arzamasov, A. A., Castillo, J. J., Couture, G., Chen, Y., Balcazo, N. P. & Lebrilla, C. B. & 12 others, Terrapon, N., Henrissat, B., Ilkayeva, O., Muehlbauer, M. J., Newgard, C. B., Mostafa, I., Das, S., Mahfuz, M., Osterman, A. L., Barratt, M. J., Ahmed, T. & Gordon, J. I., Apr 2024, In: Nature microbiology. 9, 4, p. 922-937 16 p.

Research output: Contribution to journal › Article › peer-review

Open Access

14 Scopus citations

2023

ApoE isoform- and microbiota-dependent progression of neurodegeneration in a mouse model of tauopathy

Seo, D. O., O'Donnell, D., Jain, N., Ulrich, J. D., Herz, J., Li, Y., Lemieux, M., Cheng, J., Hu, H., Serrano, J. R., Bao, X., Franke, E., Karlsson, M., Meier, M., Deng, S., Desai, C., Dodiya, H., Lelwala-Guruge, J., Handley, S. A. & Kipnis, J. & 3 others, Sisodia, S. S., Gordon, J. I. & Holtzman, D. M., Jan 13 2023, In: Science. 379, 6628, eadd1236.

Research output: Contribution to journal › Article › peer-review

Open Access

104 Scopus citations

2022

An approach for evaluating the effects of dietary fiber polysaccharides on the human gut microbiome and plasma proteome

Delannoy-Bruno, O., Desai, C., Castillo, J. J., Couture, G., Barve, R. A., Lombard, V., Henrissat, B., Cheng, J., Han, N., Hayashi, D. K., Meynier, A., Vinoy, S., Lebrilla, C. B., Marion, S., Heath, A. C., Barratt, M. J. & Gordon, J. I., May 17 2022, In: Proceedings of the National Academy of Sciences of the United States of America. 119, 20, e2123411119.

Research output: Contribution to journal › Article › peer-review

Open Access

18 Scopus citations

Erratum: Microbial liberation of N-methylserotonin from orange fiber in gnotobiotic mice and humans (Cell (2022) 185(14) (2495–2509.e11), (S0092867422007097), (10.1016/j.cell.2022.06.004))

Han, N. D., Cheng, J., Delannoy-Bruno, O., Webber, D., Terrapon, N., Henrissat, B., Rodionov, D. A., Arzamasov, A. A., Osterman, A. L., Hayashi, D. K., Meynier, A., Vinoy, S., Desai, C., Marion, S., Barratt, M. J., Heath, A. C. & Gordon, J. I., Aug 4 2022, In: Cell. 185, 16, p. 3056-3057 2 p.

Research output: Contribution to journal › Comment/debate

Open Access

11 Scopus citations

Microbial liberation of N-methylserotonin from orange fiber in gnotobiotic mice and humans

Han, N. D., Cheng, J., Delannoy-Bruno, O., Webber, D., Terrapon, N., Henrissat, B., Rodionov, D. A., Arzamasov, A. A., Osterman, A. L., Hayashi, D. K., Meynier, A., Vinoy, S., Desai, C., Marion, S., Barratt, M. J., Heath, A. C. & Gordon, J. I., Jul 7 2022, In: Cell. 185, 14, p. 2495-2509.e11

Research output: Contribution to journal › Article › peer-review

Open Access

39 Scopus citations

2021

Evaluating microbiome-directed fibre snacks in gnotobiotic mice and humans

Delannoy-Bruno, O., Desai, C., Raman, A. S., Chen, R. Y., Hibberd, M. C., Cheng, J., Han, N., Castillo, J. J., Couture, G., Lebrilla, C. B., Barve, R. A., Lombard, V., Henrissat, B., Leyn, S. A., Rodionov, D. A., Osterman, A. L., Hayashi, D. K., Meynier, A., Vinoy, S. & Kirbach, K. & 5 others, Wilmot, T., Heath, A. C., Klein, S., Barratt, M. J. & Gordon, J. I., Jul 1 2021, In: Nature. 595, 7865, p. 91-95 5 p.

Research output: Contribution to journal › Article › peer-review

78 Scopus citations

Gut microbiome contributions to altered metabolism in a pig model of undernutrition

Chang, H. W., McNulty, N. P., Hibberd, M. C., O’Donnell, D., Cheng, J., Lombard, V., Henrissat, B., Ilkayeva, O., Muehlbauer, M. J., Newgard, C. B., Barratt, M. J., Lin, X., Odle, J. & Gordon, J. I., May 25 2021, In: Proceedings of the National Academy of Sciences of the United States of America. 118, 21, e2024446118.

Research output: Contribution to journal › Article › peer-review

Open Access

17 Scopus citations

2020

Combined Prebiotic and Microbial Intervention Improves Oral Cholera Vaccination Responses in a Mouse Model of Childhood Undernutrition

Di Luccia, B., Ahern, P. P., Griffin, N. W., Cheng, J., Guruge, J. L., Byrne, A. E., Rodionov, D. A., Leyn, S. A., Osterman, A. L., Ahmed, T., Colonna, M., Barratt, M. J., Delahaye, N. F. & Gordon, J. I., Jun 10 2020, In: Cell Host and Microbe. 27, 6, p. 899-908.e5

Research output: Contribution to journal › Article › peer-review

Open Access

34 Scopus citations

Identifying determinants of bacterial fitness in a model of human gut microbial succession

Feng, L., Raman, A. S., Hibberd, M. C., Cheng, J., Griffin, N. W., Peng, Y., Leyn, S. A., Rodionov, D. A., Osterman, A. L. & Gordon, J. I., Feb 4 2020, In: Proceedings of the National Academy of Sciences of the United States of America. 117, 5, p. 2622-2633 12 p.

Research output: Contribution to journal › Article › peer-review

Open Access

27 Scopus citations

2019

Bioremediation of a Common Product of Food Processing by a Human Gut Bacterium

Wolf, A. R., Wesener, D. A., Cheng, J., Houston-Ludlam, A. N., Beller, Z. W., Hibberd, M. C., Giannone, R. J., Peters, S. L., Hettich, R. L., Leyn, S. A., Rodionov, D. A., Osterman, A. L. & Gordon, J. I., Oct 9 2019, In: Cell Host and Microbe. 26, 4, p. 463-477.e8

Research output: Contribution to journal › Article › peer-review

Open Access

40 Scopus citations

Effects of microbiota-directed foods in gnotobiotic animals and undernourished children

Gehrig, J. L., Venkatesh, S., Chang, H. W., Hibberd, M. C., Kung, V. L., Cheng, J., Chen, R. Y., Subramanian, S., Cowardin, C. A., Meier, M. F., O’Donnell, D., Talcott, M., Spears, L. D., Semenkovich, C. F., Henrissat, B., Giannone, R. J., Hettich, R. L., Ilkayeva, O., Muehlbauer, M. & Newgard, C. B. & 17 others, Sawyer, C., Head, R. D., Rodionov, D. A., Arzamasov, A. A., Leyn, S. A., Osterman, A. L., Hossain, M. I., Islam, M., Choudhury, N., Sarker, S. A., Huq, S., Mahmud, I., Mostafa, I., Mahfuz, M., Barratt, M. J., Ahmed, T. & Gordon, J. I., 2019, In: Science. 365, 6449, Y.

Research output: Contribution to journal › Article › peer-review

Open Access

291 Scopus citations

Interspecies Competition Impacts Targeted Manipulation of Human Gut Bacteria by Fiber-Derived Glycans

Patnode, M. L., Beller, Z. W., Han, N. D., Cheng, J., Peters, S. L., Terrapon, N., Henrissat, B., Le Gall, S., Saulnier, L., Hayashi, D. K., Meynier, A., Vinoy, S., Giannone, R. J., Hettich, R. L. & Gordon, J. I., Sep 19 2019, In: Cell. 179, 1, p. 59-73.e13

Research output: Contribution to journal › Article › peer-review

Open Access

217 Scopus citations

Long-Term Culture Captures Injury-Repair Cycles of Colonic Stem Cells

Wang, Y., Chiang, I. L., Ohara, T. E., Fujii, S., Cheng, J., Muegge, B. D., Ver Heul, A., Han, N. D., Lu, Q., Xiong, S., Chen, F., Lai, C. W., Janova, H., Wu, R., Whitehurst, C. E., VanDussen, K. L., Liu, T. C., Gordon, J. I., Sibley, L. D. & Stappenbeck, T. S., Nov 14 2019, In: Cell. 179, 5, p. 1144-1159.e15

Research output: Contribution to journal › Article › peer-review

Open Access

129 Scopus citations

Mechanisms by which sialylated milk oligosaccharides impact bone biology in a gnotobiotic mouse model of infant undernutrition

Cowardin, C. A., Ahern, P. P., Kung, V. L., Hibberd, M. C., Cheng, J., Guruge, J. L., Sundaresan, V., Head, R. D., Barile, D., Mills, D. A., Barratt, M. J., Huq, S., Ahmed, T. & Gordon, J. I., Jun 11 2019, In: Proceedings of the National Academy of Sciences of the United States of America. 116, 24, p. 11988-11996 9 p.

Research output: Contribution to journal › Article › peer-review

Open Access

59 Scopus citations

2017

Causal genetic variation underlying metabolome differences

Swain-Lenz, D., Nikolskiy, I., Cheng, J., Sudarsanam, P., Nayler, D., Staller, M. V. & Cohen, B. A., 2017, In: Genetics. 206, 4, p. 2199-2206 8 p.

Research output: Contribution to journal › Article › peer-review

Open Access

4 Scopus citations

Prior Dietary Practices and Connections to a Human Gut Microbial Metacommunity Alter Responses to Diet Interventions

Griffin, N. W., Ahern, P. P., Cheng, J., Heath, A. C., Ilkayeva, O., Newgard, C. B., Fontana, L. & Gordon, J. I., Jan 11 2017, In: Cell Host and Microbe. 21, 1, p. 84-96 13 p.

Research output: Contribution to journal › Article › peer-review

Open Access

132 Scopus citations

The effects of micronutrient deficiencies on bacterial species from the human gut microbiota

Hibberd, M. C., Wu, M., Rodionov, D. A., Li, X., Cheng, J., Griffin, N., Barratt, M. J., Giannone, R. J., Hettich, R. L., Osterman, A. L. & Gordon, J. I., May 17 2017, In: Science translational medicine. 9, 390, 4069.

Research output: Contribution to journal › Article › peer-review

Open Access

168 Scopus citations

2016

Effects of a gut pathobiont in a gnotobiotic mouse model of childhood undernutrition

Wagner, V. E., Dey, N., Guruge, J., Hsiao, A., Ahern, P. P., Semenkovich, N. P., Blanton, L. V., Cheng, J., Griffin, N., Stappenbeck, T., Ilkayeva, O., Newgard, C. B., Petri, W., Haque, R., Ahmed, T. & Gordon, J. I., Nov 23 2016, In: Science translational medicine. 8, 366, 4669.

Research output: Contribution to journal › Article › peer-review

Open Access

45 Scopus citations

Sialylated Milk Oligosaccharides Promote Microbiota-Dependent Growth in Models of Infant Undernutrition

Charbonneau, M. R., O'Donnell, D., Blanton, L. V., Totten, S. M., Davis, J. C. C., Barratt, M. J., Cheng, J., Guruge, J., Talcott, M., Bain, J. R., Muehlbauer, M. J., Ilkayeva, O., Wu, C., Struckmeyer, T., Barile, D., Mangani, C., Jorgensen, J., Fan, Y. M., Maleta, K. & Dewey, K. G. & 5 others, Ashorn, P., Newgard, C. B., Lebrilla, C., Mills, D. A. & Gordon, J. I., Feb 25 2016, In: Cell. 164, 5, p. 859-871 13 p.

Research output: Contribution to journal › Article › peer-review

Open Access

474 Scopus citations

2015

Erratum: Regulators of Gut Motility Revealed by a Gnotobiotic Model of Diet-Microbiome Interactions Related to Travel (Cell (2015) 163 (95-107))

Dey, N., Wagner, V. E., Blanton, L. V., Cheng, J., Fontana, L., Haque, R., Ahmed, T. & Gordon, J. I., Nov 5 2015, In: Cell. 163, 4, p. 1037 1 p.

Research output: Contribution to journal › Comment/debate

Open Access

1 Scopus citations

Genetic determinants of in vivo fitness and diet responsiveness in multiple human gut Bacteroides

Wu, M., McNulty, N. P., Rodionov, D. A., Khoroshkin, M. S., Griffin, N. W., Cheng, J., Latreille, P., Kerstetter, R. A., Terrapon, N., Henrissat, B., Osterman, A. L. & Gordon, J. I., Oct 2 2015, In: Science. 350, 6256, aac5992.

Research output: Contribution to journal › Article › peer-review

Open Access

191 Scopus citations

Regulators of Gut Motility Revealed by a Gnotobiotic Model of Diet-Microbiome Interactions Related to Travel

Dey, N., Wagner, V. E., Blanton, L. V., Cheng, J., Fontana, L., Haque, R., Ahmed, T. & Gordon, J. I., Sep 24 2015, In: Cell. 163, 1, p. 95-107 13 p.

Research output: Contribution to journal › Article › peer-review

Open Access

166 Scopus citations

2014

Bacteria from diverse habitats colonize and compete in the mouse gut

Seedorf, H., Griffin, N. W., Ridaura, V. K., Reyes, A., Cheng, J., Rey, F. E., Smith, M. I., Simon, G. M., Scheffrahn, R. H., Woebken, D., Spormann, A. M., Van Treuren, W., Ursell, L. K., Pirrung, M., Robbins-Pianka, A., Cantarel, B. L., Lombard, V., Henrissat, B., Knight, R. & Gordon, J. I., Oct 9 2014, In: Cell. 159, 2, p. 253-266 14 p.

Research output: Contribution to journal › Article › peer-review

Open Access

288 Scopus citations

Identifying gut microbe-host phenotype relationships using combinatorial communities in gnotobiotic mice

Faith, J. J., Ahern, P. P., Ridaura, V. K., Cheng, J. & Gordon, J. I., Jan 22 2014, In: Science translational medicine. 6, 220, 220ra11.

Research output: Contribution to journal › Article › peer-review

Open Access

295 Scopus citations

2013

Gut microbiomes of Malawian twin pairs discordant for kwashiorkor

Smith, M. I., Yatsunenko, T., Manary, M. J., Trehan, I., Mkakosya, R., Cheng, J., Kau, A. L., Rich, S. S., Concannon, P., Mychaleckyj, J. C., Liu, J., Houpt, E., Li, J. V., Holmes, E., Nicholson, J., Knights, D., Ursell, L. K., Knight, R. & Gordon, J. I., Feb 1 2013, In: Science. 339, 6119, p. 548-554 7 p.

Research output: Contribution to journal › Article › peer-review

Open Access

925 Scopus citations

Gut microbiota from twins discordant for obesity modulate metabolism in mice

Ridaura, V. K., Faith, J. J., Rey, F. E., Cheng, J., Duncan, A. E., Kau, A. L., Griffin, N. W., Lombard, V., Henrissat, B., Bain, J. R., Muehlbauer, M. J., Ilkayeva, O., Semenkovich, C. F., Funai, K., Hayashi, D. K., Lyle, B. J., Martini, M. C., Ursell, L. K., Clemente, J. C. & Van Treuren, W. & 5 others, Walters, W. A., Knight, R., Newgard, C. B., Heath, A. C. & Gordon, J. I., 2013, In: Science. 341, 6150, 1241214.

Research output: Contribution to journal › Article › peer-review

Open Access

2883 Scopus citations

Metabolic niche of a prominent sulfate-reducing human gut bacterium

Rey, F. E., Gonzalez, M. D., Cheng, J., Wu, M., Ahern, P. P. & Gordon, J. I., Aug 13 2013, In: Proceedings of the National Academy of Sciences of the United States of America. 110, 33, p. 13582-13587 6 p.

Research output: Contribution to journal › Article › peer-review

Open Access

301 Scopus citations

2012

Quantitative assessment of the impact of the gut microbiota on lysine ε-acetylation of host proteins using gnotobiotic mice

Simon, G. M., Cheng, J. & Gordon, J. I., Jul 10 2012, In: Proceedings of the National Academy of Sciences of the United States of America. 109, 28, p. 11133-11138 6 p.

Research output: Contribution to journal › Article › peer-review

Open Access

43 Scopus citations

The coronatine toxin of pseudomonas syringae is a multifunctional suppressor of arabidopsis defense^{W OA}

Geng, X., Cheng, J., Gangadharan, A. & Mackey, D., Nov 2012, In: Plant Cell. 24, 11, p. 4763-4774 12 p.

Research output: Contribution to journal › Article › peer-review

90 Scopus citations

2011

Potential defense-related prenylated isoflavones in lactofen-induced soybean

Cheng, J., Yuan, C. & Graham, T. L., Jun 2011, In: Phytochemistry. 72, 9, p. 875-881 7 p.

Research output: Contribution to journal › Article › peer-review

31 Scopus citations

2006

Metabonomic study of aristolochic acid-induced nephrotoxicity in rats

Chen, M., Su, M., Zhao, L., Jiang, J., Liu, P., Cheng, J., Lai, Y., Liu, Y. & Jia, W., Apr 2006, In: Journal of Proteome Research. 5, 4, p. 995-1002 8 p.

Research output: Contribution to journal › Article › peer-review

111 Scopus citations

Jiye Cheng

Research output

Search results