Research output per year
Research output per year
- 1 - 50 out of 98 results
Search results
-
2022
A benzodiazepine activator locks Kv7.1 channels open by electro-mechanical uncoupling
Schreiber, J. A., Möller, M., Zaydman, M., Zhao, L., Beller, Z., Becker, S., Ritter, N., Hou, P., Shi, J., Silva, J., Wrobel, E., Strutz-Seebohm, N., Decher, N., Schmitt, N., Meuth, S. G., Düfer, M., Wünsch, B., Cui, J. & Seebohm, G., Dec 2022, In: Communications Biology. 5, 1, 301.Research output: Contribution to journal › Article › peer-review
Open Access3 Scopus citations -
An allosteric modulator activates BK channels by perturbing coupling between Ca2+ binding and pore opening
Zhang, G., Xu, X., Jia, Z., Geng, Y., Liang, H., Shi, J., Marras, M., Abella, C., Magleby, K. L., Silva, J. R., Chen, J., Zou, X. & Cui, J., Dec 2022, In: Nature communications. 13, 1, 6784.Research output: Contribution to journal › Article › peer-review
Open Access1 Scopus citations -
Electro-mechanical coupling of KCNQ channels is a target of epilepsy-associated mutations and retigabine
Yang, N. D., Kanyo, R., Zhao, L., Li, J., Kang, P. W., Dou, A. K., White, K. M. F., Shi, J., Nerbonne, J. M., Kurata, H. T. & Cui, J., Jul 2022, In: Science Advances. 8, 29, eabo3625.Research output: Contribution to journal › Article › peer-review
1 Scopus citations -
Erratum: Author Correction: A PIP2 substitute mediates voltage sensor-pore coupling in KCNQ activation (Communications biology (2020) 3 1 (385))
Liu, Y., Xu, X., Gao, J., Naffaa, M. M., Liang, H., Shi, J., Wang, H. Z., Yang, N. D., Hou, P., Zhao, W., White, K. M. F., Kong, W., Dou, A., Cui, A., Zhang, G., Cohen, I. S., Zou, X. & Cui, J., Dec 21 2022, In: Communications Biology. 5, 1, p. 1396 1 p.Research output: Contribution to journal › Comment/debate
Open Access -
Neuronal mechanism of a BK channelopathy in absence epilepsy and dyskinesia
Dong, P., Zhang, Y., Hunanyan, A. S., Mikati, M. A., Cui, J. & Yang, H., Mar 22 2022, In: Proceedings of the National Academy of Sciences of the United States of America. 119, 12, e2200140119.Research output: Contribution to journal › Article › peer-review
Open Access1 Scopus citations -
2021
BK Channel Gating Mechanisms: Progresses Toward a Better Understanding of Variants Linked Neurological Diseases
Cui, J., Oct 21 2021, In: Frontiers in Physiology. 12, 762175.Research output: Contribution to journal › Review article › peer-review
Open Access4 Scopus citations -
Modulating the voltage sensor of a cardiac potassium channel shows antiarrhythmic effects
Lin, Y., Grinter, S. Z., Lu, Z., Xu, X., Wang, H. Z., Liang, H., Hou, P., Gao, J., Clausen, C., Shi, J., Zhao, W., Ma, Z., Liu, Y., Kelli McFarland White, M. W., Zhao, L., Kang, P. W., Zhang, G., Cohen, I. S., Zou, X. & Cui, J., May 18 2021, In: Proceedings of the National Academy of Sciences of the United States of America. 118, 20, e2024215118.Research output: Contribution to journal › Article › peer-review
Open Access4 Scopus citations -
Sonothermogenetics for noninvasive and cell-type specific deep brain neuromodulation
Yang, Y., Pacia, C. P., Ye, D., Zhu, L., Baek, H., Yue, Y., Yuan, J., Miller, M. J., Cui, J., Culver, J. P., Bruchas, M. R. & Chen, H., Jul 1 2021, In: Brain Stimulation. 14, 4, p. 790-800 11 p.Research output: Contribution to journal › Article › peer-review
Open Access19 Scopus citations -
2020
A Gain-of-Function Mutation in KCNMA1 Causes Dystonia Spells Controlled With Stimulant Therapy
Zhang, G., Gibson, R. A., McDonald, M., Liang, P., Kang, P. W., Shi, J., Yang, H., Cui, J. & Mikati, M. A., Oct 1 2020, In: Movement Disorders. 35, 10, p. 1868-1873 6 p.Research output: Contribution to journal › Article › peer-review
Open Access11 Scopus citations -
A PIP2 substitute mediates voltage sensor-pore coupling in KCNQ activation
Liu, Y., Xu, X., Gao, J., Naffaa, M. M., Liang, H., Shi, J., Wang, H. Z., Yang, N. D., Hou, P., Zhao, W., White, K. M. F., Kong, W., Dou, A., Cui, A., Zhang, G., Cohen, I. S., Zou, X. & Cui, J., Dec 1 2020, In: Communications Biology. 3, 1, 385.Research output: Contribution to journal › Article › peer-review
Open Access14 Scopus citations -
Aromatic interactions with membrane modulate human BK channel activation
Yazdani, M., Zhang, G., Jia, Z., Shi, J., Cui, J. & Chen, J., Jun 2020, In: eLife. 9, p. 1-52 52 p., e55571.Research output: Contribution to journal › Article › peer-review
Open Access1 Scopus citations -
Calmodulin acts as a state-dependent switch to control a cardiac potassium channel opening
Kang, P. W., Westerlund, A. M., Shi, J., White, K. M. F., Dou, A. K., Cui, A. H., Silva, J. R., Delemotte, L. & Cui, J., Dec 11 2020, In: Science Advances. 6, 50, eabd6798.Research output: Contribution to journal › Article › peer-review
Open Access21 Scopus citations -
Correction to: Pro-arrhythmogenic Effects of the V141M KCNQ1 Mutation in Short QT Syndrome and Its Potential Therapeutic Targets: Insights from Modeling (Journal of Medical and Biological Engineering, (2017), 37, 5, (780-789), 10.1007/s40846-017-0257-x)
Lee, H. C., Rudy, Y., Liang, H., Chen, C. C., Luo, C. H., Sheu, S. H. & Cui, J., Jun 1 2020, In: Journal of Medical and Biological Engineering. 40, 3, p. 472 1 p.Research output: Contribution to journal › Comment/debate
Open Access -
Coupling of Ca2+and voltage activation in BK channels through the aB helix/voltage sensor interface
Geng, Y., Deng, Z., Zhang, G., Budelli, G., Butler, A., Yuan, P., Cui, J., Salkoff, L. & Magleby, K. L., Jun 23 2020, In: Proceedings of the National Academy of Sciences of the United States of America. 117, 25, p. 14512-14521 10 p.Research output: Contribution to journal › Article › peer-review
Open Access8 Scopus citations -
Publisher Correction: Hydrophobic gating in BK channels (Nature Communications, (2018), 9, 1, (3408), 10.1038/s41467-018-05970-3)
Jia, Z., Yazdani, M., Zhang, G., Cui, J. & Chen, J., Dec 1 2020, In: Nature communications. 11, 1, 4497.Research output: Contribution to journal › Comment/debate
Open Access -
Structure and physiological function of the human KCNQ1 channel voltage sensor intermediate state
Taylor, K. C., Kang, P. W., Hou, P., Yang, N. D., Kuenze, G., Smith, J. A., Shi, J., Huang, H., White, K. M., Peng, D., George, A. L., Meiler, J., McFeeters, R. L., Cui, J. & Sanders, C. R., Feb 2020, In: eLife. 9, e53901.Research output: Contribution to journal › Article › peer-review
Open Access21 Scopus citations -
The action of a BK channel opener
Cui, J., Jun 2020, In: Journal of General Physiology. 152, 6, e202012571.Research output: Contribution to journal › Comment/debate
Open Access4 Scopus citations -
TMEM16A-inhibitor loaded pH-responsive nanoparticles: A novel dual-targeting antitumor therapy for lung adenocarcinoma
Guo, S., Qiu, L., Chen, Y., Wang, X., Ma, B., Qu, C., Cui, J., Zhang, H., Xing, C., Zhan, Y. & An, H., Aug 2020, In: Biochemical Pharmacology. 178, 114062.Research output: Contribution to journal › Article › peer-review
11 Scopus citations -
Two-stage electro–mechanical coupling of a KV channel in voltage-dependent activation
Hou, P., Kang, P. W., Kongmeneck, A. D., Yang, N. D., Liu, Y., Shi, J., Xu, X., White, K. M. F., Zaydman, M. A., Kasimova, M. A., Seebohm, G., Zhong, L., Zou, X., Tarek, M. & Cui, J., Dec 1 2020, In: Nature communications. 11, 1, 676.Research output: Contribution to journal › Article › peer-review
Open Access26 Scopus citations -
2019
ML277 specifically enhances the fully activated open state of KCNQ1 by modulating VSD-pore coupling
Hou, P., Shi, J., White, K. M. F., Gao, Y. & Cui, J., Jul 2019, In: eLife. 8, e48576.Research output: Contribution to journal › Article › peer-review
Open Access20 Scopus citations -
Molecular game theory for a toxin-dominant food chain model
Li, B., Silva, J. R., Lu, X., Luo, L., Wang, Y., Xu, L., Aierken, A., Shynykul, Z., Kamau, P. M., Luo, A., Yang, J., Su, D., Yang, F., Cui, J., Yang, S. & Lai, R., Nov 1 2019, In: National Science Review. 6, 6, p. 1191-1200 10 p.Research output: Contribution to journal › Article › peer-review
Open Access4 Scopus citations -
2018
Centipedes subdue giant prey by blocking KCNQ channels
Luo, L., Li, B., Wang, S., Wu, F., Wang, X., Liang, P., Ombati, R., Chen, J., Lu, X., Cui, J., Lu, Q., Zhang, L., Zhou, M., Tian, C., Yang, S. & Lai, R., Feb 13 2018, In: Proceedings of the National Academy of Sciences of the United States of America. 115, 7, p. 1646-1651 6 p.Research output: Contribution to journal › Article › peer-review
Open Access38 Scopus citations -
Hydrophobic gating in BK channels
Jia, Z., Yazdani, M., Zhang, G., Cui, J. & Chen, J., Dec 1 2018, In: Nature communications. 9, 1, 3408.Research output: Contribution to journal › Article › peer-review
Open Access43 Scopus citations -
Patch-clamp and perfusion techniques to study ion channels expressed in xenopus oocytes
Zhang, G. & Cui, J., Apr 2018, In: Cold Spring Harbor Protocols. 2018, 4, p. 258-267 10 p.Research output: Contribution to journal › Article › peer-review
5 Scopus citations -
2017
A clinical and mechanistic study of topical borneol-induced analgesia
Wang, S., Zhang, D., Hu, J., Jia, Q., Xu, W., Su, D., Song, H., Xu, Z., Cui, J., Zhou, M., Yang, J. & Xiao, J., Jun 2017, In: EMBO Molecular Medicine. 9, 6, p. 802-815 14 p.Research output: Contribution to journal › Article › peer-review
Open Access52 Scopus citations -
Deletion of cytosolic gating ring decreases gate and voltage sensor coupling in BK channels
Zhang, G., Geng, Y., Jin, Y., Shi, J., McFarland, K., Magleby, K. L., Salkoff, L. & Cui, J., Mar 6 2017, In: The Journal of general physiology. 149, 3, p. 373-387 15 p.Research output: Contribution to journal › Article › peer-review
Open Access16 Scopus citations -
Inactivation of KCNQ1 potassium channels reveals dynamic coupling between voltage sensing and pore opening
Hou, P., Eldstrom, J., Shi, J., Zhong, L., McFarland, K., Gao, Y., Fedida, D. & Cui, J., Dec 1 2017, In: Nature communications. 8, 1, 1730.Research output: Contribution to journal › Article › peer-review
Open Access39 Scopus citations -
Pro-arrhythmogenic Effects of the V141M KCNQ1 Mutation in Short QT Syndrome and Its Potential Therapeutic Targets: Insights from Modeling
Lee, H. C., Rudy, Y., Liang, H., Chen, C. C., Luo, C. H., Sheu, S. H. & Cui, J., Oct 1 2017, In: Journal of Medical and Biological Engineering. 37, 5, p. 780-789 10 p.Research output: Contribution to journal › Article › peer-review
Open Access7 Scopus citations -
Thiazolidine reacts with thioreactive biomolecules
Su, D., Nian, Y., Zhang, F., Hu, J., Cui, J., Zhou, M., Yang, J. & Wang, S., Mar 1 2017, In: Free Radical Biology and Medicine. 104, p. 272-279 8 p.Research output: Contribution to journal › Article › peer-review
1 Scopus citations -
Threading the biophysics of mammalian Slo1 channels onto structures of an invertebrate Slo1 channel
Zhou, Y., Yang, H., Cui, J. & Lingle, C. J., Nov 1 2017, In: Journal of General Physiology. 149, 11, p. 985-1007 23 p.Research output: Contribution to journal › Review article › peer-review
Open Access21 Scopus citations -
2016
Extrapolating microdomain Ca2+ dynamics using BK channels as a Ca2+ sensor
Hou, P., Xiao, F., Liu, H., Yuchi, M., Zhang, G., Wu, Y., Wang, W., Zeng, W., Ding, M., Cui, J., Wu, Z., Wang, L. Y. & Ding, J., Jan 18 2016, In: Scientific reports. 6, 17343.Research output: Contribution to journal › Article › peer-review
Open Access7 Scopus citations -
LRP6 acts as a scaffold protein in cardiac gap junction assembly
Li, J., Li, C., Liang, D., Lv, F., Yuan, T., The, E., Ma, X., Wu, Y., Zhen, L., Xie, D., Wang, S., Liu, Y., Huang, J., Shi, J., Liu, Y., Shi, D., Xu, L., Lin, L., Peng, L., Cui, J., & 2 others, Jun 2 2016, In: Nature communications. 7, 11775.Research output: Contribution to journal › Article › peer-review
Open Access28 Scopus citations -
TRPA1 and TRPV1 contribute to iodine antiseptics-associated pain and allergy
Su, D., Zhao, H., Hu, J., Tang, D., Cui, J., Zhou, M., Yang, J. & Wang, S., Oct 1 2016, In: EMBO Reports. 17, 10, p. 1422-1430 9 p.Research output: Contribution to journal › Article › peer-review
6 Scopus citations -
Ultrasound modulates ion channel currents
Kubanek, J., Shi, J., Marsh, J., Chen, D., Deng, C. & Cui, J., Apr 26 2016, In: Scientific reports. 6, 24170.Research output: Contribution to journal › Article › peer-review
Open Access160 Scopus citations -
Voltage-Dependent Gating: Novel Insights from KCNQ1 Channels
Cui, J., Jan 5 2016, In: Biophysical Journal. 110, 1, p. 14-25 12 p.Research output: Contribution to journal › Review article › peer-review
Open Access44 Scopus citations -
2015
BK channels
Yang, H. & Cui, J., Jan 1 2015, Handbook of Ion Channels. CRC Press, p. 227-239 13 p.Research output: Chapter in Book/Report/Conference proceeding › Chapter › peer-review
10 Scopus citations -
BK channels: Multiple sensors, one activation gate
Yang, H., Zhang, G. & Cui, J., 2015, In: Frontiers in Physiology. 6, FEB, 00029.Research output: Contribution to journal › Review article › peer-review
Open Access76 Scopus citations -
Direct Measurement of Cardiac Na+ Channel Conformations Reveals Molecular Pathologies of Inherited Mutations
Varga, Z., Zhu, W., Schubert, A. R., Pardieck, J. L., Krumholz, A., Hsu, E. J., Zaydman, M. A., Cui, J. & Silva, J. R., Oct 1 2015, In: Circulation: Arrhythmia and Electrophysiology. 8, 5, p. 1228-1239 12 p.Research output: Contribution to journal › Article › peer-review
Open Access26 Scopus citations -
PIP2-dependent coupling is prominent in Kv7.1 due to weakened interactions between S4-S5 and S6
Kasimova, M. A., Zaydman, M. A., Cui, J. & Tarek, M., Jan 6 2015, In: Scientific reports. 5, 7474.Research output: Contribution to journal › Article › peer-review
Open Access37 Scopus citations -
2014
A charged residue in S4 regulates coupling among the activation gate, voltage, and Ca2+ sensors in BK channels
Zhang, G., Yang, H., Liang, H., Yang, J., Shi, J., McFarland, K., Chen, Y. & Cui, J., Sep 10 2014, In: Journal of Neuroscience. 34, 37, p. 12280-12288 9 p.Research output: Contribution to journal › Article › peer-review
Open Access15 Scopus citations -
Conopeptide Vt3.1 preferentially inhibits BK potassium channels containing β4 subunits via electrostatic interactions
Li, M., Chang, S., Yang, L., Shi, J., McFarland, K., Yang, X., Moller, A., Wang, C., Zou, X., Chi, C. & Cui, J., Feb 21 2014, In: Journal of Biological Chemistry. 289, 8, p. 4735-4742 8 p.Research output: Contribution to journal › Article › peer-review
Open Access14 Scopus citations -
Domain-domain interactions determine the gating, permeation, pharmacology, and subunit modulation of the IKs ion channel
Zaydman, M. A., Kasimova, M. A., McFarland, K., Beller, Z., Hou, P., Kinser, H. E., Liang, H., Zhang, G., Shi, J., Tarek, M. & Cui, J., 2014, In: eLife. 3, p. e03606 e03606.Research output: Contribution to journal › Article › peer-review
Open Access60 Scopus citations -
Ion Channels in the Cell Membrane: Structure, Function, and Modeling
Wu, D. & Cui, J., Jul 25 2014, Physical Medicine and Rehabilitation. Elsevier, Vol. 10. p. 71-81 11 p.Research output: Chapter in Book/Report/Conference proceeding › Chapter › peer-review
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PIP2 regulation of KCNQ channels: Biophysical and molecular mechanisms for lipid modulation of voltage-dependent gating
Zaydman, M. A. & Cui, J., 2014, In: Frontiers in Physiology. 5 MAY, 00195.Research output: Contribution to journal › Review article › peer-review
Open Access84 Scopus citations -
2013
Errata to FMRP Regulates Neurotransmitter Release and Synaptic Information Transmission by Modulating Action Potential Duration via BK Channels [Neuron 77, (2013) 696-711]
Deng, P. Y., Rotman, Z., Blundon, J. A., Cho, Y., Cui, J., Cavalli, V., Zakharenko, S. S. & Klyachko, V. A., Apr 10 2013, In: Neuron. 78, 1, p. 205 1 p.Research output: Contribution to journal › Comment/debate
Open Access7 Scopus citations -
FMRP Regulates Neurotransmitter Release and Synaptic Information Transmission by Modulating Action Potential Duration via BK Channels
Deng, P. Y., Rotman, Z., Blundon, J. A., Cho, Y., Cui, J., Cavalli, V., Zakharenko, S. S. & Klyachko, V. A., Feb 20 2013, In: Neuron. 77, 4, p. 696-711 16 p.Research output: Contribution to journal › Article › peer-review
Open Access252 Scopus citations -
Interaction between residues in the Mg2+-binding site regulates BK channel activation
Yang, J., Yang, H., Sun, X., Delaloye, K., Yang, X., Moller, A., Shi, J. & Cui, J., Feb 2013, In: Journal of General Physiology. 141, 2, p. 217-228 12 p.Research output: Contribution to journal › Article › peer-review
Open Access13 Scopus citations -
Intracellular ATP binding is required to activate the slowly activating K+ channel IKs
Li, Y., Gao, J., Lu, Z., McFarland, K., Shi, J., Bock, K., Cohen, I. S. & Cui, J., Nov 19 2013, In: Proceedings of the National Academy of Sciences of the United States of America. 110, 47, p. 18922-18927 6 p.Research output: Contribution to journal › Article › peer-review
31 Scopus citations -
Kv7.1 ion channels require a lipid to couple voltage sensing to pore opening
Zaydman, M. A., Silva, J. R., Delaloye, K., Li, Y., Liang, H., Larsson, H. P., Shi, J. & Cui, J., Aug 6 2013, In: Proceedings of the National Academy of Sciences of the United States of America. 110, 32, p. 13180-13185 6 p.Research output: Contribution to journal › Article › peer-review
Open Access132 Scopus citations -
Modulation of KCNQ1 alternative splicing regulates cardiac IKs and action potential repolarization
Lee, H. C., Rudy, Y., Po-Yuan, P., Sheu, S. H., Chang, J. G. & Cui, J., Aug 2013, In: Heart rhythm. 10, 8, p. 1220-1228 9 p.Research output: Contribution to journal › Article › peer-review
1 Scopus citations