• 274 Citations

Research output per year

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Personal profile

Research interests

My clinical laboratory research interests lie in two broad areas: quantitative methods for low abundance molecules and approaches to precision medicine. As a biochemist turned clinical chemist, I am very interested in developing new assays for proteins and peptides: this includes immunoassay approaches as well as liquid-chromatography mass spectrometry methods (LC-MS/MS). As part of the Department of Endocrinology, Metabolism, and Lipid Research, I am also carrying out projects in diabetes research. We have added glycated albumin as CLIA-approved analyte to our testing menu and are seeking to fully understand its clinical utility. Additionally, we are currently enrolling women with diabetes during pregnancy to examine alternate biomarkers for predicting adverse neonatal events. These markers include glycated albumin and beta-hydroxybutyrate. As Director of the Core Laboratory for Clinical Studies, I would be happy to work with faculty who need particular assays developed for quantitation of analytes in blood or urine specimens.

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Research Output

  • 274 Citations
  • 11 Article
  • 1 Comment/debate

Elecsys® Total-Tau and Phospho-Tau (181P) CSF assays: Analytical performance of the novel, fully automated immunoassays for quantification of tau proteins in human cerebrospinal fluid

Lifke, V., Kollmorgen, G., Manuilova, E., Oelschlaegel, T., Hillringhaus, L., Widmann, M., von Arnim, C. A. F., Otto, M., Christenson, R. H., Powers, J. L., Shaw, L. M., Hansson, O., Doecke, J. D., Li, Q. X., Teunissen, C., Tumani, H. & Blennow, K., Oct 2019, In : Clinical Biochemistry. 72, p. 30-38 9 p.

Research output: Contribution to journalArticle

Open Access
  • 4 Scopus citations

    Up in smoke: Uncovering a lack of evidence for proton pump inhibitors as a source of tetrahydrocannabinol immunoassay false positives

    Powers, J. L., Rasmussen, N. N., Hurst, D. & Strathmann, F. G., Jan 1 2018, In : Pain Medicine (United States). 19, 11, p. 2196-2200 5 p.

    Research output: Contribution to journalArticle

  • 1 Scopus citations

    Thyroglobulin Antibody Screen Prior to Mass Spectrometry Provides Measurable Cost Savings and Optimal Laboratory Utilization

    Powers, J. L., Strathmann, F. G. & Straseski, J. A., Mar 1 2017, In : American journal of clinical pathology. 147, 3, p. 309-314 6 p.

    Research output: Contribution to journalArticle

    Open Access
  • 2 Scopus citations

    Multigene and Drug Interaction Approach for Tamoxifen Metabolite Patterns Reveals Possible Involvement of CYP2C9, CYP2C19, and ABCB1

    Powers, J. L., Buys, S. S., Fletcher, D., Melis, R., Johnson-Davis, K. L., Lyon, E., Malmberg, E. M. & McMillin, G. A., Jan 1 2016, In : Journal of clinical pharmacology. 56, 12, p. 1570-1581 12 p.

    Research output: Contribution to journalArticle

  • 13 Scopus citations