Research output per year
Research output per year
Personal profile
Research interests
My research focuses on the identification of tumor specific mutant antigens recognized by the immune system as foreign that serve as the target of a T-cell response against tumors. We take advantage of cancer genomics and bioinformatics techniques to detect tumor-specific mutations that accumulate during transformation and use this information to predict which mutations are potentially antigenic.
Areas of Clinical Interest
Cancer/tumor immunotherapy
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Research output
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cDC1 prime and are licensed by CD4+ T cells to induce anti-tumour immunity
Ferris, S. T., Durai, V., Wu, R., Theisen, D. J., Ward, J. P., Bern, M. D., Davidson, J. T., Bagadia, P., Liu, T., Briseño, C. G., Li, L., Gillanders, W. E., Wu, G. F., Yokoyama, W. M., Murphy, T. L., Schreiber, R. D. & Murphy, K. M., Aug 27 2020, In: Nature. 584, 7822, p. 624-629 6 p.Research output: Contribution to journal › Article › peer-review
7 Scopus citations -
Key Parameters of Tumor Epitope Immunogenicity Revealed Through a Consortium Approach Improve Neoantigen Prediction
The Tumor Neoantigen Selection Alliance, Oct 29 2020, In: Cell. 183, 3, p. 818-834.e13Research output: Contribution to journal › Article › peer-review
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Circulating tumor DNA profiling in small-cell lung cancer identifies potentially targetable alterations
Devarakonda, S., Sankararaman, S., Herzog, B. H., Gold, K. A., Waqar, S. N., Ward, J. P., Raymond, V. M., Lanman, R. B., Chaudhuri, A. A., Owonikoko, T. K., Li, B. T., Poirier, J. T., Rudin, C. M., Govindan, R. & Morgensztern, D., Oct 15 2019, In: Clinical Cancer Research. 25, 20, p. 6119-6126 8 p.Research output: Contribution to journal › Article › peer-review
4 Scopus citations -
MHC-II neoantigens shape tumour immunity and response to immunotherapy
Alspach, E., Lussier, D. M., Miceli, A. P., Kizhvatov, I., DuPage, M., Luoma, A. M., Meng, W., Lichti, C. F., Esaulova, E., Vomund, A. N., Runci, D., Ward, J. P., Gubin, M. M., Medrano, R. F. V., Arthur, C. D., White, J. M., Sheehan, K. C. F., Chen, A., Wucherpfennig, K. W., Jacks, T. & 3 others, , Oct 31 2019, In: Nature. 574, 7780, p. 696-701 6 p.Research output: Contribution to journal › Article › peer-review
83 Scopus citations -
Erratum: High-Dimensional Analysis Delineates Myeloid and Lymphoid Compartment Remodeling during Successful Immune-Checkpoint Cancer Therapy (Cell (2018) 175(4) (1014–1030.e19), (S009286741831242X) (10.1016/j.cell.2018.09.030))
Gubin, M. M., Esaulova, E., Ward, J. P., Malkova, O. N., Runci, D., Wong, P., Noguchi, T., Arthur, C. D., Meng, W., Alspach, E., Medrano, R. F. V., Fronick, C., Fehlings, M., Newell, E. W., Fulton, R., Sheehan, K., Oh, S., Schreiber, R. & Artomov, M., Nov 15 2018, In: Cell. 175, 5, p. 1443 1 p.Research output: Contribution to journal › Comment/debate
13 Scopus citations