Research output per year
Research output per year
Search results
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2025
Genetically Engineered Brain Organoids Recapitulate Spatial and Developmental States of Glioblastoma Progression
Ishahak, M., Han, R. H., Annamalai, D., Woodiwiss, T., McCornack, C., Cleary, R. T., DeSouza, P. A., Qu, X., Dahiya, S., Kim, A. H. & Millman, J. R., 2025, (Accepted/In press) In: Advanced Science.Research output: Contribution to journal › Article › peer-review
Open Access -
2024
Comparative and integrative single cell analysis reveals new insights into the transcriptional immaturity of stem cell-derived β cells
Schmidt, M. D., Ishahak, M., Augsornworawat, P. & Millman, J. R., Dec 2024, In: BMC genomics. 25, 1, 105.Research output: Contribution to journal › Article › peer-review
Open Access5 Scopus citations -
Hypoimmune induced pluripotent stem cells survive long term in fully immunocompetent, allogeneic rhesus macaques
Hu, X., White, K., Olroyd, A. G., DeJesus, R., Dominguez, A. A., Dowdle, W. E., Friera, A. M., Young, C., Wells, F., Chu, E. Y., Ito, C. E., Krishnapura, H., Jain, S., Ankala, R., McGill, T. J., Lin, A., Egenberger, K., Gagnon, A., Michael Rukstalis, J. & Hogrebe, N. J. & 9 others, , Mar 2024, In: Nature Biotechnology. 42, 3, p. 413-423 11 p.Research output: Contribution to journal › Article › peer-review
Open Access53 Scopus citations -
Identification of unique cell type responses in pancreatic islets to stress
Maestas, M. M., Ishahak, M., Augsornworawat, P., Veronese-Paniagua, D. A., Maxwell, K. G., Velazco-Cruz, L., Marquez, E., Sun, J., Shunkarova, M., Gale, S. E., Urano, F. & Millman, J. R., Dec 2024, In: Nature communications. 15, 1, 5567.Research output: Contribution to journal › Article › peer-review
Open Access5 Scopus citations -
2023
A Predictive Oxygen Durability Model to Analyze Oxygen Consumption of Insulin Producing Cells Encapsulated Within a Highly Oxygenated Hydrogel
Domingo-Lopez, D. A., Levey, R. E., Brennan, B., Carroll, O., Gale, S. E., Millman, J. R., McDonough, L., Kelly, H. M., Ronan, W. & Duffy, G. P., Jan 10 2023, In: Advanced Materials Technologies. 8, 1, 2200643.Research output: Contribution to journal › Article › peer-review
Open Access1 Scopus citations -
Human hypoimmune primary pancreatic islets avoid rejection and autoimmunity and alleviate diabetes in allogeneic humanized mice
Hu, X., Gattis, C., Olroyd, A. G., Friera, A. M., White, K., Young, C., Basco, R., Lamba, M., Wells, F., Ankala, R., Dowdle, W. E., Lin, A., Egenberger, K., Rukstalis, J. M., Millman, J. R., Connolly, A. J., Deuse, T. & Schrepfer, S., Apr 12 2023, In: Science translational medicine. 15, 691, eadg5794.Research output: Contribution to journal › Article › peer-review
36 Scopus citations -
Single-nucleus multi-omics of human stem cell-derived islets identifies deficiencies in lineage specification
Augsornworawat, P., Hogrebe, N. J., Ishahak, M., Schmidt, M. D., Marquez, E., Maestas, M. M., Veronese-Paniagua, D. A., Gale, S. E., Miller, J. R., Velazco-Cruz, L. & Millman, J. R., Jun 2023, In: Nature Cell Biology. 25, 6, p. 904-916 13 p.Research output: Contribution to journal › Article › peer-review
Open Access22 Scopus citations -
2022
Differential Function and Maturation of Human Stem Cell-Derived Islets after Transplantation
Maxwell, K. G., Kim, M. H., Gale, S. E. & Millman, J. R., Mar 2022, In: Stem Cells Translational Medicine. 11, 3, p. 322-331 10 p.Research output: Contribution to journal › Article › peer-review
Open Access25 Scopus citations -
Multidimensional analysis and therapeutic development using patient iPSC–derived disease models of Wolfram syndrome
Kitamura, R. A., Maxwell, K. G., Ye, W., Kries, K., Brown, C. M., Augsornworawat, P., Hirsch, Y., Johansson, M. M., Weiden, T., Ekstein, J., Cohen, J., Klee, J., Leslie, K., Simeonov, A., Henderson, M. J., Millman, J. R. & Urano, F., Sep 22 2022, In: JCI Insight. 7, 18, e156549.Research output: Contribution to journal › Article › peer-review
Open Access15 Scopus citations -
2021
A nanofibrous encapsulation device for safe delivery of insulin-producing cells to treat type 1 diabetes
Wang, X., Maxwell, K. G., Wang, K., Bowers, D. T., Flanders, J. A., Liu, W., Wang, L. H., Liu, Q., Liu, C., Naji, A., Wang, Y., Wang, B., Chen, J., Ernst, A. U., Melero-Martin, J. M., Millman, J. R. & Ma, M., Jun 2 2021, In: Science translational medicine. 13, 596, eabb4601.Research output: Contribution to journal › Article › peer-review
Open Access89 Scopus citations -
Heterogeneity of Diabetes: β-Cells, Phenotypes, and Precision Medicine: Proceedings of an International Symposium of the Canadian Institutes of Health Research's Institute of Nutrition, Metabolism and Diabetes and the U.S. National Institutes of Health's National Institute of Diabetes and Digestive and Kidney Diseases
symposium planning committee, moderators, and speakers, Dec 2021, In: Canadian Journal of Diabetes. 45, 8, p. 697-713 17 p.Research output: Contribution to journal › Article › peer-review
Open Access2 Scopus citations -
Mouse Pluripotent Stem Cell Differentiation Under Physiological Oxygen Reduces Residual Teratomas
Millman, J. R., Tan, J. H. & Colton, C. K., Dec 2021, In: Cellular and Molecular Bioengineering. 14, 6, p. 555-567 13 p.Research output: Contribution to journal › Article › peer-review
5 Scopus citations -
2020
Single-Cell Transcriptome Profiling Reveals β Cell Maturation in Stem Cell-Derived Islets after Transplantation
Augsornworawat, P., Maxwell, K. G., Velazco-Cruz, L. & Millman, J. R., Aug 25 2020, In: Cell Reports. 32, 8, 108067.Research output: Contribution to journal › Article › peer-review
Open Access113 Scopus citations -
SIX2 Regulates Human β Cell Differentiation from Stem Cells and Functional Maturation In Vitro
Velazco-Cruz, L., Goedegebuure, M. M., Maxwell, K. G., Augsornworawat, P., Hogrebe, N. J. & Millman, J. R., May 26 2020, In: Cell Reports. 31, 8, 107687.Research output: Contribution to journal › Article › peer-review
Open Access33 Scopus citations -
Targeting the cytoskeleton to direct pancreatic differentiation of human pluripotent stem cells
Hogrebe, N. J., Augsornworawat, P., Maxwell, K. G., Velazco-Cruz, L. & Millman, J. R., Apr 1 2020, In: Nature Biotechnology. 38, 4, p. 460-470 11 p.Research output: Contribution to journal › Article › peer-review
Open Access235 Scopus citations -
2019
Acquisition of Dynamic Function in Human Stem Cell-Derived β Cells
Velazco-Cruz, L., Song, J., Maxwell, K. G., Goedegebuure, M. M., Augsornworawat, P., Hogrebe, N. J. & Millman, J. R., Feb 12 2019, In: Stem Cell Reports. 12, 2, p. 351-365 15 p.Research output: Contribution to journal › Article › peer-review
Open Access272 Scopus citations -
A hydrogel platform for in vitro three dimensional assembly of human stem cell-derived islet cells and endothelial cells
Augsornworawat, P., Velazco-Cruz, L., Song, J. & Millman, J. R., Oct 1 2019, In: Acta Biomaterialia. 97, p. 272-280 9 p.Research output: Contribution to journal › Article › peer-review
42 Scopus citations -
Measurement of energy metabolism in explanted retinal tissue using extracellular flux analysis
Millman, J. R., Doggett, T., Thebeau, C., Zhang, S., Semenkovich, C. F. & Rajagopal, R., Jan 2019, In: Journal of Visualized Experiments. 2019, 143, e58626.Research output: Contribution to journal › Article › peer-review
Open Access15 Scopus citations -
2017
Economic 3D-printing approach for transplantation of human stem cell-derived β-like cells
Song, J. & Millman, J. R., Mar 2017, In: Biofabrication. 9, 1, 015002.Research output: Contribution to journal › Article › peer-review
Open Access67 Scopus citations -
2016
Generation of stem cell-derived β-cells from patients with type 1 diabetes
Millman, J. R., Xie, C., Van Dervort, A., Gürtler, M., Pagliuca, F. W. & Melton, D. A., May 10 2016, In: Nature communications. 7, 11463.Research output: Contribution to journal › Article › peer-review
Open Access321 Scopus citations -
Long-term glycemic control using polymer-encapsulated human stem cell-derived beta cells in immune-competent mice
Vegas, A. J., Veiseh, O., Gürtler, M., Millman, J. R., Pagliuca, F. W., Bader, A. R., Doloff, J. C., Li, J., Chen, M., Olejnik, K., Tam, H. H., Jhunjhunwala, S., Langan, E., Aresta-Dasilva, S., Gandham, S., McGarrigle, J. J., Bochenek, M. A., Hollister-Lock, J., Oberholzer, J. & Greiner, D. L. & 4 others, , Mar 1 2016, In: Nature medicine. 22, 3, p. 306-311 6 p.Research output: Contribution to journal › Article › peer-review
Open Access560 Scopus citations -
2014
Differentiated human stem cells resemble fetal, not adult, β cells
Hrvatin, S., O'Donnell, C. W., Deng, F., Millman, J. R., Pagliuca, F. W., DiIorio, P., Rezania, A., Gifford, D. K. & Melton, D. A., Feb 25 2014, In: Proceedings of the National Academy of Sciences of the United States of America. 111, 8, p. 3038-3043 6 p.Research output: Contribution to journal › Article › peer-review
Open Access244 Scopus citations -
Generation of functional human pancreatic β cells in vitro
Pagliuca, F. W., Millman, J. R., Gürtler, M., Segel, M., Van Dervort, A., Ryu, J. H., Peterson, Q. P., Greiner, D. & Melton, D. A., Oct 9 2014, In: Cell. 159, 2, p. 428-439 12 p.Research output: Contribution to journal › Article › peer-review
Open Access1604 Scopus citations -
2010
Accurate control of oxygen level in cells during culture on silicone rubber membranes with application to stem cell differentiation
Powers, D. E., Millman, J. R., Bonner-Weir, S., Rappel, M. J. & Colton, C. K., May 2010, In: Biotechnology Progress. 26, 3, p. 805-818 14 p.Research output: Contribution to journal › Article › peer-review
19 Scopus citations -
2008
Effects of oxygen on mouse embryonic stem cell growth, phenotype retention, and cellular energetics
Powers, D. E., Millman, J. R., Huang, R. B. & Colton, C. K., Oct 1 2008, In: Biotechnology and Bioengineering. 101, 2, p. 241-254 14 p.Research output: Contribution to journal › Article › peer-review
Open Access55 Scopus citations -
2004
Fabrication and Study of Simple and Robust Microfluidic Devices
Hill, R., Millman, J. & Velev, O. D., Mar 2004, In: Pharmaceutical Engineering. 24, 2, p. 98-110 13 p.Research output: Contribution to journal › Article › peer-review
5 Scopus citations