Research output per year
Research output per year
- 38 results
Search results
-
2024
Disruption of polyunsaturated fatty acid biosynthesis drives STING-dependent acute myeloid leukemia cell maturation and death
Kanefsky, J., Basse, M., Sokei, J., di Martino, O., Valin, L., Jaspers, Y., Martinez, E., Huhn, J., Di Marcantonio, D., Magee, J. A., Goldman, A. R., Tang, H. Y., Ferraro, F., Kemp, S., Wiest, D. L. & Sykes, S. M., May 2024, In: Journal of Biological Chemistry. 300, 5, 107214.Research output: Contribution to journal › Article › peer-review
Open Access4 Scopus citations -
Kmt2c restricts G-CSF-driven HSC mobilization and granulocyte production in a methyltransferase-independent manner
Wang, H. C., Chen, R., Yang, W., Li, Y., Muthukumar, R., Patel, R. M., Casey, E. B., Denby, E. & Magee, J. A., Aug 27 2024, In: Cell Reports. 43, 8, 114542.Research output: Contribution to journal › Article › peer-review
Open Access -
LIN28B promotes differentiation of fully transformed AML cells but is dispensable for fetal leukemia suppression
Li, Y., Mendoza-Castrejon, J., Patel, R. M., Casey, E. B., Denby, E., Bryder, D. & Magee, J. A., Mar 2024, In: Leukemia. 38, 3, p. 648-651 4 p.Research output: Contribution to journal › Letter › peer-review
1 Scopus citations -
2023
A fetal tumor suppressor axis abrogates MLL-fusion-driven acute myeloid leukemia
Eldeeb, M., Yuan, O., Guzzi, N., Thi Ngoc, P. C., Konturek-Ciesla, A., Kristiansen, T. A., Muthukumar, S., Magee, J., Bellodi, C., Yuan, J. & Bryder, D., Feb 28 2023, In: Cell Reports. 42, 2, 112099.Research output: Contribution to journal › Article › peer-review
Open Access7 Scopus citations -
Basal type I interferon signaling has only modest effects on neonatal and juvenile hematopoiesis
Li, Y., Yang, W., Wang, H. C., Patel, R. M., Casey, E. B., Denby, E. & Magee, J. A., Jun 13 2023, In: Blood Advances. 7, 11, p. 2609-2621 13 p.Research output: Contribution to journal › Article › peer-review
Open Access4 Scopus citations -
FLT3ITD drives context-specific changes in cell identity and variable interferon dependence during AML initiation
Li, Y., Yang, W., Patel, R. M., Casey, E. B., Denby, E., Mendoza-Castrejon, J., Rodriguez-Lopez, P. & Magee, J. A., Mar 23 2023, In: Blood. 141, 12, p. 1442-1456 15 p.Research output: Contribution to journal › Article › peer-review
Open Access8 Scopus citations -
Integration of Genomic Sequencing Drives Therapeutic Targeting of PDGFRA in T-Cell Acute Lymphoblastic Leukemia/Lymphoblastic Lymphoma
Paolino, J., Dimitrov, B., Winger, B. A., Sandoval-Perez, A., Rangarajan, A. V., Ocasio-Martinez, N., Tsai, H. K., Li, Y., Robichaud, A. L., Khalid, D., Hatton, C., Gillani, R., Polonen, P., Dilig, A., Gotti, G., Kavanagh, J., Adhav, A. A., Gow, S., Tsai, J. & Li, Y. D. & 20 others, , 2023, In: Clinical Cancer Research. 29, 22, p. 4613-4626 14 p.Research output: Contribution to journal › Article › peer-review
Open Access3 Scopus citations -
Layered immunity and layered leukemogenicity: Developmentally restricted mechanisms of pediatric leukemia initiation
Mendoza-Castrejon, J. & Magee, J. A., May 2023, In: Immunological Reviews. 315, 1, p. 197-215 19 p.Research output: Contribution to journal › Review article › peer-review
4 Scopus citations -
2022
A somatic mutation in moesin drives progression into acute myeloid leukemia
Yuan, O., Ugale, A., de Marchi, T., Anthonydhason, V., Konturek-Ciesla, A., Wan, H., Eldeeb, M., Drabe, C., Jassinskaja, M., Hansson, J., Hidalgo, I., Velasco-Hernandez, T., Cammenga, J., Magee, J. A., Niméus, E. & Bryder, D., Apr 2022, In: Science Advances. 8, 16, eabm9987.Research output: Contribution to journal › Article › peer-review
Open Access2 Scopus citations -
Macrophage NOX2 NADPH oxidase maintains alveolar homeostasis in mice
Bhattacharya, S., Idol, R. A., Yang, W., Rojas Márquez, J. D., Li, Y., Huang, G., Beatty, W. L., Atkinson, J. J., Brumell, J. H., Bagaitkar, J., Magee, J. A. & Dinauer, M. C., May 12 2022, In: Blood. 139, 19, p. 2855-2870 16 p.Research output: Contribution to journal › Article › peer-review
Open Access16 Scopus citations -
Single-cell RNA transcriptome analysis of CNS immune cells reveals CXCL16/CXCR6 as maintenance factors for tissue-resident T cells that drive synapse elimination
Rosen, S. F., Soung, A. L., Yang, W., Ai, S., Kanmogne, M., Davé, V. A., Artyomov, M., Magee, J. A. & Klein, R. S., Dec 2022, In: Genome medicine. 14, 1, 108.Research output: Contribution to journal › Article › peer-review
Open Access35 Scopus citations -
2021
Developmental Stage-Specific Changes in Protein Synthesis Differentially Sensitize Hematopoietic Stem Cells and Erythroid Progenitors to Impaired Ribosome Biogenesis
Magee, J. A. & Signer, R. A. J., Jan 12 2021, In: Stem Cell Reports. 16, 1, p. 20-28 9 p.Research output: Contribution to journal › Article › peer-review
Open Access24 Scopus citations -
Kmt2c mutations enhance HSC self-renewal capacity and convey a selective advantage after chemotherapy
Chen, R., Okeyo-Owuor, T., Patel, R. M., Casey, E. B., Cluster, A. S., Yang, W. & Magee, J. A., Feb 16 2021, In: Cell Reports. 34, 7, 108751.Research output: Contribution to journal › Article › peer-review
Open Access17 Scopus citations -
Matched targeted therapy for pediatric patients with relapsed, refractory, or high-risk leukemias: A report from the leap consortium
Pikman, Y., Tasian, S. K., Sulis, M. L., Stevenson, K., Blonquist, T. M., Apsel Winger, B., Cooper, T. M., Pauly, M., Maloney, K. W., Burke, M. J., Brown, P. A., Gossai, N., McNeer, J. L., Shukla, N. N., Cole, P. D., Kahn, J. M., Chen, J., Barth, M. J., Magee, J. A. & Gennarini, L. & 33 others, , 2021, In: Cancer discovery. 11, 6, p. 1424-1439 16 p.Research output: Contribution to journal › Article › peer-review
Open Access28 Scopus citations -
Pediatric hodgkin lymphoma, version 3.2021
Flerlage, J. E., Hiniker, S. M., Armenian, S., Benya, E. C., Bobbey, A. J., Chang, V., Cooper, S., Coulter, D. W., Cuglievan, B., Hoppe, B. S., Isenalumhe, L., Kelly, K., Kersun, L., Lamble, A. J., Larrier, N. A., Magee, J., Oduro, K., Pacheco, M., Price, A. P. & Roberts, K. B. & 7 others, , Jun 2021, In: JNCCN Journal of the National Comprehensive Cancer Network. 19, 6, p. 733-754 22 p.Research output: Contribution to journal › Review article › peer-review
Open Access24 Scopus citations -
Transcriptional reprogramming in neonatal hematopoietic stem and progenitor cells
Li, Y. & Magee, J. A., Sep 2021, In: Experimental Hematology. 101-102, p. 25-33 9 p.Research output: Contribution to journal › Review article › peer-review
Open Access7 Scopus citations -
2020
Single-Cell Analysis of Neonatal HSC Ontogeny Reveals Gradual and Uncoordinated Transcriptional Reprogramming that Begins before Birth
Li, Y., Kong, W., Yang, W., Patel, R. M., Casey, E. B., Okeyo-Owuor, T., White, J. M., Porter, S. N., Morris, S. A. & Magee, J. A., Nov 5 2020, In: Cell Stem Cell. 27, 5, p. 732-747.e7Research output: Contribution to journal › Article › peer-review
Open Access60 Scopus citations -
TLR2/6 signaling promotes the expansion of premalignant hematopoietic stem and progenitor cells in the NUP98–HOXD13 mouse model of MDS
Monlish, D. A., Greenberg, Z. J., Bhatt, S. T., Leonard, K. M., Romine, M. P., Dong, Q., Bendesky, L., Duncavage, E. J., Magee, J. A. & Schuettpelz, L. G., Aug 2020, In: Experimental Hematology. 88, p. 42-55 14 p.Research output: Contribution to journal › Article › peer-review
Open Access9 Scopus citations -
2019
The efficiency of murine MLL-ENL-driven leukemia initiation changes with age and peaks during neonatal development
Okeyo-Owuor, T., Li, Y., Patel, R. M., Yang, W., Casey, E. B., Cluster, A. S., Porter, S. N., Bryder, D. & Magee, J. A., 2019, In: Blood Advances. 3, 15, p. 2388-2399 12 p.Research output: Contribution to journal › Article › peer-review
Open Access19 Scopus citations -
2017
Comment on: Genomics of primary chemoresistance and remission induction failure in paediatric and adult acute myeloid leukaemia
Magee, J. A., Jan 1 2017, In: British Journal of Haematology. 176, 1, p. 5-6 2 p.Research output: Contribution to journal › Editorial
Open Access1 Scopus citations -
PRKCH regulates hematopoietic stem cell function and predicts poor prognosis in acute myeloid leukemia
Porter, S. N. & Magee, J. A., Sep 2017, In: Experimental Hematology. 53, p. 43-47 5 p.Research output: Contribution to journal › Article › peer-review
Open Access14 Scopus citations -
Sleepwalking stem cells
Magee, J. A., Apr 6 2017, In: Blood. 129, 14, p. 1887-1888 2 p.Research output: Contribution to journal › Comment/debate
Open Access -
2016
Fetal and neonatal hematopoietic progenitors are functionally and transcriptionally resistant to Flt3-ITD mutations
Porter, S. N., Cluster, A. S., Yang, W., Busken, K. A., Patel, R. M., Ryoo, J. & Magee, J. A., Nov 23 2016, In: eLife. 5, NOVEMBER2016, e18882.Research output: Contribution to journal › Article › peer-review
Open Access28 Scopus citations -
Pten cell autonomously modulates the hematopoietic stem cell response to inflammatory cytokines
Porter, S. N., Cluster, A. S., Signer, R. A. J., Voigtmann, J., Monlish, D. A., Schuettpelz, L. G. & Magee, J. A., Jun 14 2016, In: Stem Cell Reports. 6, 6, p. 806-814 9 p.Research output: Contribution to journal › Article › peer-review
Open Access22 Scopus citations -
2015
Protein kinase N3 deficiency impedes PI3-kinase pathway-driven leukemogenesis without affecting normal hematopoiesis
Kraus, M., Dolinski, B., Rosahl, T. W. & Magee, J. A., Jan 10 2015, In: Leukemia. 29, 1, p. 255-258 4 p.Research output: Contribution to journal › Letter › peer-review
3 Scopus citations -
2014
Haematopoietic stem cells require a highly regulated protein synthesis rate
Signer, R. A. J., Magee, J. A., Salic, A. & Morrison, S. J., 2014, In: Nature. 508, 7498, p. 49-54 6 p.Research output: Contribution to journal › Article › peer-review
Open Access495 Scopus citations -
2013
Expression of BCR/ABL p210 from a Knockin Allele Enhances Bone Marrow Engraftment without Inducing Neoplasia
Foley, S. B., Hildenbrand, Z. L., Soyombo, A. A., Magee, J. A., Wu, Y., Oravecz-Wilson, K. I. & Ross, T. S., Oct 17 2013, In: Cell Reports. 5, 1, p. 51-60 10 p.Research output: Contribution to journal › Article › peer-review
Open Access34 Scopus citations -
Oncogenic Nras has bimodal effects on stem cells that sustainably increase competitiveness
Li, Q., Bohin, N., Wen, T., Ng, V., Magee, J., Chen, S. C., Shannon, K. & Morrison, S. J., 2013, In: Nature. 504, 7478, p. 143-147 5 p.Research output: Contribution to journal › Article › peer-review
Open Access104 Scopus citations -
2012
Cancer Stem Cells: Impact, Heterogeneity, and Uncertainty
Magee, J. A., Piskounova, E. & Morrison, S. J., Mar 20 2012, In: Cancer Cell. 21, 3, p. 283-296 14 p.Research output: Contribution to journal › Review article › peer-review
Open Access981 Scopus citations -
Temporal changes in PTEN and mTORC2 regulation of hematopoietic stem cell self-renewal and leukemia suppression
Magee, J. A., Ikenoue, T., Nakada, D., Lee, J. Y., Guan, K. L. & Morrison, S. J., Sep 7 2012, In: Cell Stem Cell. 11, 3, p. 415-428 14 p.Research output: Contribution to journal › Article › peer-review
Open Access173 Scopus citations -
2006
A systematic model to predict transcriptional regulatory mechanisms based on overrepresentation of transcription factor binding profiles
Chang, L. W., Nagarajan, R., Magee, J. A., Milbrandt, J. & Stormo, G. D., Mar 2006, In: Genome research. 16, 3, p. 405-413 9 p.Research output: Contribution to journal › Article › peer-review
Open Access61 Scopus citations -
Direct, androgen receptor-mediated regulation of the FKBP5 gene via a distal enhancer element
Magee, J. A., Chang, L. W., Stormo, G. D. & Milbrandt, J., Jan 2006, In: Endocrinology. 147, 1, p. 590-598 9 p.Research output: Contribution to journal › Article › peer-review
Open Access145 Scopus citations -
2003
Haploinsufficiency at the Nkx3.1 locus: A paradigm for stochastic, dosage-sensitive gene regulation during tumor initiation
Magee, J. A., Abdulkadir, S. A. & Milbrandt, J., Mar 2003, In: Cancer Cell. 3, 3, p. 273-283 11 p.Research output: Contribution to journal › Article › peer-review
Open Access123 Scopus citations -
2002
Conditional loss of Nkx3.1 in adult mice induces prostatic intraepithelial neoplasia
Abdulkadir, S. A., Magee, J. A., Peters, T. J., Kaleem, Z., Naughton, C. K., Humphrey, P. A. & Milbrandt, J., 2002, In: Molecular and cellular biology. 22, 5, p. 1495-1503 9 p.Research output: Contribution to journal › Article › peer-review
Open Access200 Scopus citations -
2001
Bringing the human genome and the revolution in bioinformatics to the medical school classroom: A case report from Washington University School of Medicine
Magee, J., Gordon, J. I. & Whelan, A., 2001, In: Academic Medicine. 76, 8, p. 852-855 4 p.Research output: Contribution to journal › Review article › peer-review
Open Access16 Scopus citations -
Expression profiling reveals hepsin overexpression in prostate cancer
Magee, J. A., Araki, T., Patil, S., Ehrig, T., Humphrey, P. A., Watson, M. A., Milbrandt, J., Catalona, W. J. & True, L., Aug 1 2001, In: Cancer research. 61, 15, p. 5692-5696 5 p.Research output: Contribution to journal › Article › peer-review
358 Scopus citations -
1997
Intercompartmental signaling and the regulation of vestigial expression at the dorsoventral boundary of the developing Drosophila wing
Kim, J., Magee, J. & Carroll, S. B., Dec 1 1997, In: Cold Spring Harbor symposia on quantitative biology. 62, p. 283-291 9 p.Research output: Contribution to journal › Article › peer-review
11 Scopus citations -
1996
Integration of positional signals and regulation of wing formation and identity by Drosophila vestigial gene
Kim, J., Sebring, A., Esch, J. J., Kraus, M. E., Vorwerk, K., Magee, J. & Carroll, S. B., Jul 11 1996, In: Nature. 382, 6587, p. 133-138 6 p.Research output: Contribution to journal › Article › peer-review
412 Scopus citations