Jeffrey Henderson

Associate Professor of Medicine, Associate Professor of Molecular Microbiology

    • Source: Scopus
    19992020

    Research output per year

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    Research interests

    The Henderson laboratory uses interdisciplinary approaches to better understand infection pathogenesis and to identify new diagnostic and therapeutic strategies. To do this, we combine patient-oriented studies with new biochemical approaches to identify how virulence-associated bacterial pathogens cause disease. Guided by these results, we seek a mechanistic understanding of infection physiology. Of particular interest are the multifunctional roles of small molecules associated with iron scavenging – called siderophores. New properties and host interactions have been identified for bacterial siderophores using a combination of biochemical and pathophysiologic approaches including mass spectrometry-based metabolomics, bacterial genetics, protein chemistry, and infection models.

    Areas of Clinical Interest

    Infectious diseases

    Keywords

    • COVID-19

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