Jeffrey Haspel

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Jeffrey Haspel

Associate Professor of Medicine

 https://orcid.org/0000-0001-5839-0265

    Willing to Mentor

    Available to Mentor:

    PhD/MSTP Students

    • 10442
      Citations
    1992 …2024

    Research activity per year

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    • 2024

      Diurnal rhythms in varicella vaccine effectiveness

      Danino, D., Kalron, Y., Haspel, J. A. & Hazan, G., Oct 22 2024, In: JCI Insight. 9, 20, e184452.

      Research output: Contribution to journal › Article › peer-review

      Open Access

    • Multi-organ phenotypes in mice lacking latent TGFβ binding protein 2 (LTBP2)

      Bodmer, N. K., Knutsen, R. H., Roth, R. A., Castile, R. M., Brodt, M. D., Gierasch, C. M., Broekelmann, T., Gibson, M. A., Haspel, J. A., Lake, S. P., Koenitzer, J. R., Brody, S. L., Silva, M. J., Mecham, R. & Ornitz, D. M., Feb 2024, In: Developmental Dynamics. 253, 2, p. 233-254 22 p.

      Research output: Contribution to journal › Article › peer-review

      Open Access
      5 Scopus citations

    • Nanoparticle targeting of neutrophil glycolysis prevents lung ischemia-reperfusion injury

      Liao, F., Scozzi, D., Zhou, D., Maksimos, M., Diedrich, C., Cano, M., Tague, L. K., Liu, Z., Haspel, J. A., Leonard, J. M., Li, W., Krupnick, A. S., Wong, B. W., Kreisel, D., Azab, A. K. & Gelman, A. E., Aug 2024, In: American Journal of Transplantation. 24, 8, p. 1382-1394 13 p.

      Research output: Contribution to journal › Article › peer-review

      2 Scopus citations
    • 2023

      Biological rhythms in COVID-19 vaccine effectiveness in an observational cohort study of 1.5 million patients

      Hazan, G., Duek, O. A., Alapi, H., Mok, H., Ganninger, A., Ostendorf, E., Gierasch, C., Chodick, G., Greenberg, D. & Haspel, J. A., Jun 1 2023, In: Journal of Clinical Investigation. 133, 11, e167339.

      Research output: Contribution to journal › Article › peer-review

      Open Access
      23 Scopus citations
    • 2022

      Age-dependent rebound in asthma exacerbations after COVID-19 lockdown

      Hazan, G., Fox, C., Mok, H. & Haspel, J., Nov 2022, In: Journal of Allergy and Clinical Immunology: Global. 1, 4, p. 314-318 5 p.

      Research output: Contribution to journal › Article › peer-review

      Open Access
      9 Scopus citations

    • Age-Dependent Reduction in Asthmatic Pathology through Reprogramming of Postviral Inflammatory Responses

      Hazan, G., Eubanks, A., Gierasch, C., Atkinson, J., Fox, C., Hernandez-Leyva, A., Rosen, A. L., Kau, A. L., Agapov, E., Alexander-Brett, J., Steinberg, D., Kelley, D., White, M., Byers, D., Wu, K., Keeler, S. P., Zhang, Y., Koenitzer, J. R., Eiden, E. & Anderson, N. & 2 others, Holtzman, M. J. & Haspel, J., Mar 15 2022, In: Journal of Immunology. 208, 6, p. 1467-1482 16 p.

      Research output: Contribution to journal › Article › peer-review

      Open Access
      9 Scopus citations

    • Effect of the COVID-19 Lockdown on Asthma Biological Rhythms

      Hazan, G., Fox, C., Eiden, E., Anderson, N., Friger, M. & Haspel, J., Apr 2022, In: Journal of Biological Rhythms. 37, 2, p. 152-163 12 p.

      Research output: Contribution to journal › Article › peer-review

      Open Access
      8 Scopus citations
    • 2019

      Diurnal Rhythms Spatially and Temporally Organize Autophagy

      Ryzhikov, M., Ehlers, A., Steinberg, D., Xie, W., Oberlander, E., Brown, S., Gilmore, P. E., Townsend, R. R., Lane, W. S., Dolinay, T., Nakahira, K., Choi, A. M. K. & Haspel, J. A., Feb 12 2019, In: Cell Reports. 26, 7, p. 1880-1892.e6

      Research output: Contribution to journal › Article › peer-review

      Open Access
      49 Scopus citations

    • Measuring diurnal rhythms in autophagic and proteasomal flux

      Ryzhikov, M., Eubanks, A. & Haspel, J. A., 2019, In: Journal of Visualized Experiments. 2019, 151, e60133.

      Research output: Contribution to journal › Article › peer-review

      4 Scopus citations
    • 2018

      BMAL1 links the circadian clock to viral airway pathology and asthma phenotypes

      Ehlers, A., Xie, W., Agapov, E., Brown, S., Steinberg, D., Tidwell, R., Sajol, G., Schutz, R., Weaver, R., Yu, H., Castro, M., Bacharier, L. B., Wang, X., Holtzman, M. J. & Haspel, J. A., Jan 1 2018, In: Mucosal Immunology. 11, 1, p. 97-111 15 p.

      Research output: Contribution to journal › Article › peer-review

      Open Access
      119 Scopus citations

    • Cell-Autonomous Regulation of Astrocyte Activation by the Circadian Clock Protein BMAL1

      Lananna, B. V., Nadarajah, C. J., Izumo, M., Cedeño, M. R., Xiong, D. D., Dimitry, J., Tso, C. F., McKee, C. A., Griffin, P., Sheehan, P. W., Haspel, J. A., Barres, B. A., Liddelow, S. A., Takahashi, J. S., Karatsoreos, I. N. & Musiek, E. S., Oct 2 2018, In: Cell Reports. 25, 1, p. 1-9.e5

      Research output: Contribution to journal › Article › peer-review

      Open Access
      108 Scopus citations

    • Establishment of the early cilia preassembly protein complex during motile ciliogenesis

      Horani, A., Ustione, A., Huang, T., Firth, A. L., Pan, J., Gunsten, S. P., Haspel, J. A., Piston, D. W. & Brody, S. L., Feb 6 2018, In: Proceedings of the National Academy of Sciences of the United States of America. 115, 6, p. E1221-E1228

      Research output: Contribution to journal › Article › peer-review

      Open Access
      54 Scopus citations
    • 2017

      Clocks stop sugar shock

      Haspel, J., Apr 5 2017, In: Science translational medicine. 9, 384, eaan2772.

      Research output: Contribution to journal › Article › peer-review

    • Guidelines for Genome-Scale Analysis of Biological Rhythms

      Hughes, M. E., Abruzzi, K. C., Allada, R., Anafi, R., Arpat, A. B., Asher, G., Baldi, P., de Bekker, C., Bell-Pedersen, D., Blau, J., Brown, S., Ceriani, M. F., Chen, Z., Chiu, J. C., Cox, J., Crowell, A. M., DeBruyne, J. P., Dijk, D. J., DiTacchio, L. & Doyle, F. J. & 73 others, Duffield, G. E., Dunlap, J. C., Eckel-Mahan, K., Esser, K. A., FitzGerald, G. A., Forger, D. B., Francey, L. J., Fu, Y. H., Gachon, F., Gatfield, D., de Goede, P., Golden, S. S., Green, C., Harer, J., Harmer, S., Haspel, J., Hastings, M. H., Herzel, H., Herzog, E. D., Hoffmann, C., Hong, C., Hughey, J. J., Hurley, J. M., de la Iglesia, H. O., Johnson, C., Kay, S. A., Koike, N., Kornacker, K., Kramer, A., Lamia, K., Leise, T., Lewis, S. A., Li, J., Li, X., Liu, A. C., Loros, J. J., Martino, T. A., Menet, J. S., Merrow, M., Millar, A. J., Mockler, T., Naef, F., Nagoshi, E., Nitabach, M. N., Olmedo, M., Nusinow, D. A., Ptáček, L. J., Rand, D., Reddy, A. B., Robles, M. S., Roenneberg, T., Rosbash, M., Ruben, M. D., Rund, S. S. C., Sancar, A., Sassone-Corsi, P., Sehgal, A., Sherrill-Mix, S., Skene, D. J., Storch, K. F., Takahashi, J. S., Ueda, H. R., Wang, H., Weitz, C., Westermark, P. O., Wijnen, H., Xu, Y., Wu, G., Yoo, S. H., Young, M., Zhang, E. E., Zielinski, T. & Hogenesch, J. B., Oct 1 2017, In: Journal of Biological Rhythms. 32, 5, p. 380-393 14 p.

      Research output: Contribution to journal › Article › peer-review

      Open Access
      187 Scopus citations

    • Long noncoding RNA FOXD3-AS1 regulates oxidative stress-induced apoptosis via sponging microRNA-150

      Zhang, D., Lee, H., Haspel, J. A. & Jin, Y., Oct 2017, In: FASEB Journal. 31, 10, p. 4472-4481 10 p.

      Research output: Contribution to journal › Article › peer-review

      Open Access
      65 Scopus citations
    • 2016

      MicroRNA-15a/16 regulates apoptosis of lung epithelial cells after oxidative stress

      Cao, Y., Zhang, D., Moon, H. G., Lee, H., Haspel, J. A., Hu, K., Xie, L. & Jin, Y., 2016, In: Molecular Medicine. 22, p. 233-243 11 p.

      Research output: Contribution to journal › Article › peer-review

      Open Access
      16 Scopus citations
    • 2014

      Circadian rhythm reprogramming during lung inflammation

      Haspel, J. A., Chettimada, S., Shaik, R. S., Chu, J. H., Raby, B. A., Cernadas, M., Carey, V., Process, V., Hunninghake, G. M., Ifedigbo, E., Lederer, J. A., Englert, J., Pelton, A., Coronata, A., Fredenburgh, L. E. & Choi, A. M. K., Sep 11 2014, In: Nature communications. 5, 4753.

      Research output: Contribution to journal › Article › peer-review

      Open Access
      166 Scopus citations

    • Metabolomic derangements are associated with mortality in critically ill adult patients

      Rogers, A. J., McGeachie, M., Baron, R. M., Gazourian, L., Haspel, J. A., Nakahira, K., Fredenburgh, L. E., Hunninghake, G. M., Raby, B. A., Matthay, M. A., Otero, R. M., Fowler, V. G., Rivers, E. P., Woods, C. W., Kingsmore, S., Langley, R. J. & Choi, A. M. K., Jan 30 2014, In: PloS one. 9, 1, e87538.

      Research output: Contribution to journal › Article › peer-review

      Open Access
      121 Scopus citations
    • 2013

      Autophagic flux and oxidative capacity of skeletal muscles during acute starvation

      Mofarrahi, M., Guo, Y., Haspel, J. A., Choi, A. M. K., Davis, E. C., Gouspillou, G., Hepple, R. T., Godin, R., Burelle, Y. & Hussain, S. N. A., Oct 2013, In: Autophagy. 9, 10, p. 1604-1620 17 p.

      Research output: Contribution to journal › Article › peer-review

      Open Access
      63 Scopus citations

    • Histone deacetylase 6-mediated selective autophagy regulates copd-associated cilia dysfunction

      Lam, H. C., Cloonan, S. M., Bhashyam, A. R., Haspel, J. A., Singh, A., Sathirapongsasuti, J. F., Cervo, M., Yao, H., Chung, A. L., Mizumura, K., An, C. H., Shan, B., Franks, J. M., Haley, K. J., Owen, C. A., Tesfaigzi, Y., Washko, G. R., Quackenbush, J., Silverman, E. K. & Rahman, I. & 5 others, Kim, H. P., Mahmood, A., Biswal, S. S., Ryter, S. W. & Choi, A. M. K., Dec 2 2013, In: Journal of Clinical Investigation. 123, 12, p. 5212-5230 19 p.

      Research output: Contribution to journal › Article › peer-review

      Open Access
      256 Scopus citations

    • Syndecan-2 exerts antifibrotic effects by promoting caveolin-1-mediated transforming growth factor-b receptor i internalization and inhibiting transforming growth factor-b1 signaling

      Shi, Y., Gochuico, B. R., Yu, G., Tang, X., Osorio, J. C., Fernandez, I. E., Risquez, C. F., Patel, A. S., Shi, Y., Wathelet, M. G., Goodwin, A. J., Haspel, J. A., Ryter, S. W., Billings, E. M., Kaminski, N., Morse, D. & Rosas, I. O., Oct 1 2013, In: American journal of respiratory and critical care medicine. 188, 7, p. 831-841 11 p.

      Research output: Contribution to journal › Article › peer-review

      Open Access
      51 Scopus citations
    • 2012

      Autophagy in idiopathic pulmonary fibrosis

      Patel, A. S., Lin, L., Geyer, A., Haspel, J. A., An, C. H., Cao, J., Rosas, I. O. & Morse, D., Jul 18 2012, In: PloS one. 7, 7, e41394.

      Research output: Contribution to journal › Article › peer-review

      Open Access
      323 Scopus citations

    • Autophagy in pulmonary diseases

      Ryter, S. W., Nakahira, K., Haspel, J. A. & Choi, A. M. K., 2012, In: Annual review of physiology. 74, p. 377-401 25 p.

      Research output: Contribution to journal › Article › peer-review

      92 Scopus citations

    • Guidelines for the use and interpretation of assays for monitoring autophagy

      Klionsky, D. J., Abdalla, F. C., Abeliovich, H., Abraham, R. T., Acevedo-Arozena, A., Adeli, K., Agholme, L., Agnello, M., Agostinis, P., Aguirre-Ghiso, J. A., Ahn, H. J., Ait-Mohamed, O., Ait-Si-Ali, S., Akematsu, T., Akira, S., Al-Younes, H. M., Al-Zeer, M. A., Albert, M. L., Albin, R. L. & Alegre-Abarrategui, J. & 1,249 others, Aleo, M. F., Alirezaei, M., Almasan, A., Almonte-Becerril, M., Amano, A., Amaravadi, R., Amarnath, S., Amer, A. O., Andrieu-Abadie, N., Anantharam, V., Ann, D. K., Anoopkumar-Dukie, S., Aoki, H., Apostolova, N., Arancia, G., Aris, J. P., Asanuma, K., Asare, N. Y. O., Ashida, H., Askanas, V., Askew, D. S., Auberger, P., Baba, M., Backues, S. K., Baehrecke, E. H., Bahr, B. A., Bai, X. Y., Bailly, Y., Baiocchi, R., Baldini, G., Balduini, W., Ballabio, A., Bamber, B. A., Bampton, E. T. W., Bánhegyi, G., Bartholomew, C. R., Bassham, D. C., Bast, R. C., Batoko, H., Bay, B. H., Beau, I., Béchet, D. M., Begley, T. J., Behl, C., Behrends, C., Bekri, S., Bellaire, B., Bendall, L. J., Benetti, L., Berliocchi, L., Bernardi, H., Bernassola, F., Besteiro, S., Bhatia-Kissova, I., Bi, X., Biard-Piechaczyk, M., Blum, J. S., Boise, L. H., Bonaldo, P., Boone, D. L., Bornhauser, B. C., Bortoluci, K. R., Bossis, I., Bost, F., Bourquin, J. P., Boya, P., Boyer-Guittaut, M., Bozhkov, P. V., Brady, N. R., Brancolini, C., Brech, A., Brenman, J. E., Brennand, A., Bresnick, E. H., Brest, P., Bridges, D., Bristol, M. L., Brookes, P. S., Brown, E. J., Brumell, J. H., Brunetti-Pierri, N., Brunk, U. T., Bulman, D. E., Bultman, S. J., Bultynck, G., Burbulla, L. F., Bursch, W., Butchar, J. P., Buzgariu, W., Bydlowski, S. P., Cadwell, K., Cahová, M., Cai, D., Cai, J., Cai, Q., Calabretta, B., Calvo-Garrido, J., Camougrand, N., Campanella, M., Campos-Salinas, J., Candi, E., Cao, L., Caplan, A. B., Carding, S. R., Cardoso, S. M., Carew, J. S., Carlin, C. R., Carmignac, V., Carneiro, L. A. M., Carra, S., Caruso, R. A., Casari, G., Casas, C., Castino, R., Cebollero, E., Cecconi, F., Celli, J., Chaachouay, H., Chae, H. J., Chai, C. Y., Chan, D. C., Chan, E. Y., Chang, R. C. C., Che, C. M., Chen, C. C., Chen, G. C., Chen, G. Q., Chen, M., Chen, Q., Chen, S. S. L., Chen, W. L., Chen, X., Chen, X., Chen, X., Chen, Y. G., Chen, Y., Chen, Y., Chen, Y. J., Chen, Z., Cheng, A., Cheng, C. H. K., Cheng, Y., Cheong, H., Cheong, J. H., Cherry, S., Chess-Williams, R., Cheung, Z. H., Chevet, E., Chiang, H. L., Chiarelli, R., Chiba, T., Chin, L. S., Chiou, S. H., Chisari, F. V., Cho, C. H., Cho, D. H., Choi, A. M. K., Choi, D. S., Choi, K. S., Choi, M. E., Chouaib, S., Choubey, D., Choubey, V., Chu, C. T., Chuang, T. H., Chueh, S. H., Chun, T., Chwae, Y. J., Chye, M. L., Ciarcia, R., Ciriolo, M. R., Clague, M. J., Clark, R. S. B., Clarke, P. G. H., Clarke, R., Codogno, P., Coller, H. A., Colombo, M. I., Comincini, S., Condello, M., Condorelli, F., Cookson, M. R., Coombs, G. H., Coppens, I., Corbalan, R., Cossart, P., Costelli, P., Costes, S., Coto-Montes, A., Couve, E., Coxon, F. P., Cregg, J. M., Crespo, J. L., Cronjé, M. J., Cuervo, A. M., Cullen, J. J., Czaja, M. J., D'Amelio, M., Darfeuille-Michaud, A., Davids, L. M., Davies, F. E., De Felici, M., De Groot, J. F., De Haan, C. A. M., De Martino, L., De Milito, A., De Tata, V., Debnath, J., Degterev, A., Dehay, B., Delbridge, L. M. D., Demarchi, F., Deng, Y. Z., Dengjel, J., Dent, P., Denton, D., Deretic, V., Desai, S. D., Devenish, R. J., Di Gioacchino, M., Di Paolo, G., Di Pietro, C., Díaz-Araya, G., Díaz-Laviada, I., Diaz-Meco, M. T., Diaz-Nido, J., Dikic, I., Dinesh-Kumar, S. P., Ding, W. X., Distelhorst, C. W., Diwan, A., Djavaheri-Mergny, M., Dokudovskaya, S., Dong, Z., Dorsey, F. C., Dosenko, V., Dowling, J. J., Doxsey, S., Dreux, M., Drew, M. E., Duan, Q., Duchosal, M. A., Duff, K., Dugail, I., Durbeej, M., Duszenko, M., Edelstein, C. L., Edinger, A. L., Egea, G., Eichinger, L., Eissa, N. T., Ekmekcioglu, S., El-Deiry, W. S., Elazar, Z., Elgendy, M., Ellerby, L. M., Er Eng, K., Engelbrecht, A. M., Engelender, S., Erenpreisa, J., Escalante, R., Esclatine, A., Eskelinen, E. L., Espert, L., Espina, V., Fan, H., Fan, J., Fan, Q. W., Fan, Z., Fang, S., Fang, Y., Fanto, M., Fanzani, A., Farkas, T., Farré, J. C., Faure, M., Fechheimer, M., Feng, C. G., Feng, J., Feng, Q., Feng, Y., Fésüs, L., Feuer, R., Figueiredo-Pereira, M. E., Fimia, G. M., Fingar, D. C., Finkbeiner, S., Finkel, T., Finley, K. D., Fiorito, F., Fisher, E. A., Fisher, P. B., Flajolet, M., Florez-McClure, M. L., Florio, S., Fon, E. A., Fornai, F., Fortunato, F., Fotedar, R., Fowler, D. H., Fox, H. S., Franco, R., Frankel, L. B., Fransen, M., Fuentes, J. M., Fueyo, J., Fujii, J., Fujisaki, K., Fujita, E., Fukuda, M., Furukawa, R. H., Gaestel, M., Gailly, P., Gajewska, M., Galliot, B., Galy, V., Ganesh, S., Ganetzky, B., Ganley, I. G., Gao, F. B., Gao, G. F., Gao, J., Garcia, L., Garcia-Manero, G., Garcia-Marcos, M., Garmyn, M., Gartel, A. L., Gatti, E., Gautel, M., Gawriluk, T. R., Gegg, M. E., Geng, J., Germain, M., Gestwicki, J. E., Gewirtz, D. A., Ghavami, S., Ghosh, P., Giammarioli, A. M., Giatromanolaki, A. N., Gibson, S. B., Gilkerson, R. W., Ginger, M. L., Ginsberg, H. N., Golab, J., Goligorsky, M. S., Golstein, P., Gomez-Manzano, C., Goncu, E., Gongora, C., Gonzalez, C. D., Gonzalez, R., González-Estévez, C., González-Polo, R. A., Gonzalez-Rey, E., Gorbunov, N. V., Gorski, S., Goruppi, S., Gottlieb, R. A., Gozuacik, D., Granato, G. E., Grant, G. D., Green, K. N., Gregorc, A., Gros, F., Grose, C., Grunt, T. W., Gual, P., Guan, J. L., Guan, K. L., Guichard, S. M., Gukovskaya, A. S., Gukovsky, I., Gunst, J., Gustafsson, A. B., Halayko, A. J., Hale, A. N., Halonen, S. K., Hamasaki, M., Han, F., Han, T., Hancock, M. K., Hansen, M., Harada, H., Harada, M., Hardt, S. E., Harper, J. W., Harris, A. L., Harris, J., Harris, S. D., Hashimoto, M., Haspel, J. A., Hayashi, S. I., Hazelhurst, L. A., He, C., He, Y. W., Hébert, M. J., Heidenreich, K. A., Helfrich, M. H., Helgason, G. V., Henske, E. P., Herman, B., Herman, P. K., Hetz, C., Hilfiker, S., Hill, J. A., Hocking, L. J., Hofman, P., Hofmann, T. G., Höhfeld, J., Holyoake, T. L., Hong, M. H., Hood, D. A., Hotamisligil, G. S., Houwerzijl, E. J., Høyer-Hansen, M., Hu, B., Hu, C. A. A., Hu, H. M., Hua, Y., Huang, C., Huang, J., Huang, S., Huang, W. P., Huber, T. B., Huh, W. K., Hung, T. H., Hupp, T. R., Hur, G. M., Hurley, J. B., Hussain, S. N. A., Hussey, P. J., Hwang, J. J., Hwang, S., Ichihara, A., Ilkhanizadeh, S., Inoki, K., Into, T., Iovane, V., Iovanna, J. L., Ip, N. Y., Isaka, Y., Ishida, H., Isidoro, C., Isobe, K. I., Iwasaki, A., Izquierdo, M., Izumi, Y., Jaakkola, P. M., Jäättelä, M., Jackson, G. R., Jackson, W. T., Janji, B., Jendrach, M., Jeon, J. H., Jeung, E. B., Jiang, H., Jiang, H., Jiang, J. X., Jiang, M., Jiang, Q., Jiang, X., Jiménez, A., Jin, M., Jin, S., Joe, C. O., Johansen, T., Johnson, D. E., Johnson, G. V. W., Jones, N. L., Joseph, B., Joseph, S. K., Joubert, A. M., Juhász, G., Juillerat-Jeanneret, L., Jung, C. H., Jung, Y. K., Kaarniranta, K., Kaasik, A., Kabuta, T., Kadowaki, M., Kagedal, K., Kamada, Y., Kaminskyy, V. O., Kampinga, H. H., Kanamori, H., Kang, C., Kang, K. B., Il Kang, K., Kang, R., Kang, Y. A., Kanki, T., Kanneganti, T. D., Kanno, H., Kanthasamy, A. G., Kanthasamy, A., Karantza, V., Kaushal, G. P., Kaushik, S., Kawazoe, Y., Ke, P. Y., Kehrl, J. H., Kelekar, A., Kerkhoff, C., Kessel, D. H., Khalil, H., Kiel, J. A. K. W., Kiger, A. A., Kihara, A., Kim, D. R., Kim, D. H., Kim, D. H., Kim, E. K., Kim, H. R., Kim, J. S., Kim, J. H., Kim, J. C., Kim, J. K., Kim, P. K., Kim, S. W., Kim, Y. S., Kim, Y., Kimchi, A., Kimmelman, A. C., King, J. S., Kinsella, T. J., Kirkin, V., Kirshenbaum, L. A., Kitamoto, K., Kitazato, K., Klein, L., Klimecki, W. T., Klucken, J., Knecht, E., Ko, B. C. B., Koch, J. C., Koga, H., Koh, J. Y., Koh, Y. H., Koike, M., Komatsu, M., Kominami, E., Kong, H. J., Kong, W. J., Korolchuk, V. I., Kotake, Y., Koukourakis, M. I., Kouri Flores, J. B., Kovács, A. L., Kraft, C., Krainc, D., Krämer, H., Kretz-Remy, C., Krichevsky, A. M., Kroemer, G., Krüger, R., Krut, O., Ktistakis, N. T., Kuan, C. Y., Kucharczyk, R., Kumar, A., Kumar, R., Kumar, S., Kundu, M., Kung, H. J., Kurz, T., Kwon, H. J., La Spada, A. R., Lafont, F., Lamark, T., Landry, J., Lane, J. D., Lapaquette, P., Laporte, J. F., László, L., Lavandero, S., Lavoie, J. N., Layfield, R., Lazo, P. A., Le, W., Le Cam, L., Ledbetter, D. J., Lee, A. J. X., Lee, B. W., Lee, G. M., Lee, J., Lee, J. H., Lee, M., Lee, M. S., Lee, S. H., Leeuwenburgh, C., Legembre, P., Legouis, R., Lehmann, M., Lei, H. Y., Lei, Q. Y., Leib, D. A., Leiro, J., Lemasters, J. J., Lemoine, A., Lesniak, M. S., Lev, D., Levenson, V. V., Levine, B., Levy, E., Li, F., Li, J. L., Li, L., Li, S., Li, W., Li, X. J., Li, Y. B., Li, Y. P., Liang, C., Liang, Q., Liao, Y. F., Liberski, P. P., Lieberman, A., Lim, H. J., Lim, K. L., Lim, K., Lin, C. F., Lin, F. C., Lin, J., Lin, J. D., Lin, K., Lin, W. W., Lin, W. C., Lin, Y. L., Linden, R., Lingor, P., Lippincott-Schwartz, J., Lisanti, M. P., Liton, P. B., Liu, B., Liu, C. F., Liu, K., Liu, L., Liu, Q. A., Liu, W., Liu, Y. C., Liu, Y., Lockshin, R. A., Lok, C. N., Lonial, S., Loos, B., Lopez-Berestein, G., López-Otín, C., Lossi, L., Lotze, M. T., Lõw, P., Lu, B., Lu, B., Lu, B., Lu, Z., Luciano, F., Lukacs, N. W., Lund, A. H., Lynch-Day, M. A., Ma, Y., Macian, F., MacKeigan, J. P., Macleod, K. F., Madeo, F., Maiuri, L., Maiuri, M. C., Malagoli, D., Malicdan, M. C. V., Malorni, W., Man, N., Mandelkow, E. M., Manon, S., Manov, I., Mao, K., Mao, X., Mao, Z., Marambaud, P., Marazziti, D., Marcel, Y. L., Marchbank, K., Marchetti, P., Marciniak, S. J., Marcondes, M., Mardi, M., Marfe, G., Mariño, G., Markaki, M., Marten, M. R., Martin, S. J., Martinand-Mari, C., Martinet, W., Martinez-Vicente, M., Masini, M., Matarrese, P., Matsuo, S., Matteoni, R., Mayer, A., Mazure, N. M., McConkey, D. J., McConnell, M. J., McDermott, C., McDonald, C., McInerney, G. M., McKenna, S. L., McLaughlin, B. A., McLean, P. J., McMaster, C. R., McQuibban, G. A., Meijer, A. J., Meisler, M. H., Meléndez, A., Melia, T. J., Melino, G., Mena, M. A., Menendez, J. A., Menna-Barreto, R. F. S., Menon, M. B., Menzies, F. M., Mercer, C. A., Merighi, A., Merry, D. E., Meschini, S., Meyer, C. G., Meyer, T. F., Miao, C. Y., Miao, J. Y., Michels, P. A. M., Michiels, C., Mijaljica, D., Milojkovic, A., Minucci, S., Miracco, C., Miranti, C. K., Mitroulis, I., Miyazawa, K., Mizushima, N., Mograbi, B., Mohseni, S., Molero, X., Mollereau, B., Mollinedo, F., Momoi, T., Monastyrska, I., Monick, M. M., Monteiro, M. J., Moore, M. N., Mora, R., Moreau, K., Moreira, P. I., Moriyasu, Y., Moscat, J., Mostowy, S., Mottram, J. C., Motyl, T., Moussa, C. E. H., Müller, S., Muller, S., Münger, K., Münz, C., Murphy, L. O., Murphy, M. E., Musarò, A., Mysorekar, I., Nagata, E., Nagata, K., Nahimana, A., Nair, U., Nakagawa, T., Nakahira, K., Nakano, H., Nakatogawa, H., Nanjundan, M., Naqvi, N. I., Narendra, D. P., Narita, M., Navarro, M., Nawrocki, S. T., Nazarko, T. Y., Nemchenko, A., Netea, M. G., Neufeld, T. P., Ney, P. A., Nezis, I. P., Nguyen, H. P., Nie, D., Nishino, I., Nislow, C., Nixon, R. A., Noda, T., Noegel, A. A., Nogalska, A., Noguchi, S., Notterpek, L., Novak, I., Nozaki, T., Nukina, N., Nürnberger, T., Nyfeler, B., Obara, K., Oberley, T. D., Oddo, S., Ogawa, M., Ohashi, T., Okamoto, K., Oleinick, N. L., Oliver, F. J., Olsen, L. J., Olsson, S., Opota, O., Osborne, T. F., Ostrander, G. K., Otsu, K., Ou, J. H. J., Ouimet, M., Overholtzer, M., Ozpolat, B., Paganetti, P., Pagnini, U., Pallet, N., Palmer, G. E., Palumbo, C., Pan, T., Panaretakis, T., Pandey, U. B., Papackova, Z., Papassideri, I., Paris, I., Park, J., Park, O. K., Parys, J. B., Parzych, K. R., Patschan, S., Patterson, C., Pattingre, S., Pawelek, J. M., Peng, J., Perlmutter, D. H., Perrotta, I., Perry, G., Pervaiz, S., Peter, M., Peters, G. J., Petersen, M., Petrovski, G., Phang, J. M., Piacentini, M., Pierre, P., Pierrefite-Carle, V., Pierron, G., Pinkas-Kramarski, R., Piras, A., Piri, N., Platanias, L. C., Pöggeler, S., Poirot, M., Poletti, A., Poüs, C., Pozuelo-Rubio, M., Prætorius-Ibba, M., Prasad, A., Prescott, M., Priault, M., Produit-Zengaffinen, N., Progulske-Fox, A., Proikas-Cezanne, T., Przedborski, S., Przyklenk, K., Puertollano, R., Puyal, J., Qian, S. B., Qin, L., Qin, Z. H., Quaggin, S. E., Raben, N., Rabinowich, H., Rabkin, S. W., Rahman, I., Rami, A., Ramm, G., Randall, G., Randow, F., Rao, V. A., Rathmell, J. C., Ravikumar, B., Ray, S. K., Reed, B. H., Reed, J. C., Reggiori, F., Régnier-Vigouroux, A., Reichert, A. S., Reiners, J. J., Reiter, R. J., Ren, J., Revuelta, J. L., Rhodes, C. J., Ritis, K., Rizzo, E., Robbins, J., Roberge, M., Roca, H., Roccheri, M. C., Rocchi, S., Rodemann, H. P., De Córdoba, S. R., Rohrer, B., Roninson, I. B., Rosen, K., Rost-Roszkowska, M. M., Rouis, M., Rouschop, K. M. A., Rovetta, F., Rubin, B. P., Rubinsztein, D. C., Ruckdeschel, K., Rucker, E. B., Rudich, A., Rudolf, E., Ruiz-Opazo, N., Russo, R., Rusten, T. E., Ryan, K. M., Ryter, S. W., Sabatini, D. M., Sadoshima, J., Saha, T., Saitoh, T., Sakagami, H., Sakai, Y., Salekdeh, G. H., Salomoni, P., Salvaterra, P. M., Salvesen, G., Salvioli, R., Sanchez, A. M. J., Sánchez-Alcázar, J. A., Sánchez-Prieto, R., Sandri, M., Sankar, U., Sansanwal, P., Santambrogio, L., Saran, S., Sarkar, S., Sarwal, M., Sasakawa, C., Sasnauskiene, A., Sass, M., Sato, K., Sato, M., Schapira, A. H. V., Scharl, M., Schätzl, H. M., Scheper, W., Schiaffino, S., Schneider, C., Schneider, M. E., Schneider-Stock, R., Schoenlein, P. V., Schorderet, D. F., Schüller, C., Schwartz, G. K., Scorrano, L., Sealy, L., Seglen, P. O., Segura-Aguilar, J., Seiliez, I., Seleverstov, O., Sell, C., Seo, J. B., Separovic, D., Setaluri, V., Setoguchi, T., Settembre, C., Shacka, J. J., Shanmugam, M., Shapiro, I. M., Shaulian, E., Shaw, R. J., Shelhamer, J. H., Shen, H. M., Shen, W. C., Sheng, Z. H., Shi, Y., Shibuya, K., Shidoji, Y., Shieh, J. J., Shih, C. M., Shimada, Y., Shimizu, S., Shintani, T., Shirihai, O. S., Shore, G. C., Sibirny, A. A., Sidhu, S. B., Sikorska, B., Silva-Zacarin, E. C. M., Simmons, A., Simon, A. K., Simon, H. U., Simone, C., Simonsen, A., Sinclair, D. A., Singh, R., Sinha, D., Sinicrope, F. A., Sirko, A., Siu, P. M., Sivridis, E., Skop, V., Skulachev, V. P., Slack, R. S., Smaili, S. S., Smith, D. R., Soengas, M. S., Soldati, T., Song, X., Sood, A. K., Soong, T. W., Sotgia, F., Spector, S. A., Spies, C. D., Springer, W., Srinivasula, S. M., Stefanis, L., Steffan, J. S., Stendel, R., Stenmark, H., Stephanou, A., Stern, S. T., Sternberg, C., Stork, B., Strålfors, P., Subauste, C. S., Sui, X., Sulzer, D., Sun, J., Sun, S. Y., Sun, Z. J., Sung, J. J. Y., Suzuki, K., Suzuki, T., Swanson, M. S., Swanton, C., Sweeney, S. T., Sy, L. K., Szabadkai, G., Tabas, I., Taegtmeyer, H., Tafani, M., Takács-Vellai, K., Takano, Y., Takegawa, K., Takemura, G., Takeshita, F., Talbot, N. J., Tan, K. S. W., Tanaka, K., Tanaka, K., Tang, D., Tang, D., Tanida, I., Tannous, B. A., Tavernarakis, N., Taylor, G. S., Taylor, G. A., Taylor, J. P., Terada, A. S., Terman, A., Tettamanti, G., Thevissen, K., Thompson, C. B., Thorburn, A., Thumm, M., Tian, F. F., Tian, Y., Tocchini-Valentini, G., Tolkovsky, A. M., Tomino, Y., Tönges, L., Tooze, S. A., Tournier, C., Tower, J., Towns, R., Trajkovic, V., Travassos, L. H., Tsai, T. F., Tschan, M. P., Tsubata, T., Tsung, A., Turk, B., Turner, L. S., Tyagi, S. C., Uchiyama, Y., Ueno, T., Umekawa, M., Umemiya-Shirafuji, R., Unni, V. K., Vaccaro, M. I., Valente, E. M., Van Den Berghe, G., Van Der Klei, I. J., Van Doorn, W. G., Van Dyk, L. F., Van Egmond, M., Van Grunsven, L. A., Vandenabeele, P., Vandenberghe, W. P., Vanhorebeek, I., Vaquero, E. C., Velasco, G., Vellai, T., Vicencio, J. M., Vierstra, R. D., Vila, M., Vindis, C., Viola, G., Viscomi, M. T., Voitsekhovskaja, O. V., Von Haefen, C., Votruba, M., Wada, K., Wade-Martins, R., Walker, C. L., Walsh, C. M., Walter, J., Wan, X. B., Wang, A., Wang, C., Wang, D., Wang, F., Wang, F., Wang, G., Wang, H., Wang, H. G., Wang, H. D., Wang, J., Wang, K., Wang, M., Wang, R. C., Wang, X., Wang, X., Wang, Y. J., Wang, Y., Wang, Z., Wang, Z. C., Wang, Z., Wansink, D. G., Ward, D. M., Watada, H., Waters, S. L., Webster, P., Wei, L., Weihl, C. C., Weiss, W. A., Welford, S. M., Wen, L. P., Whitehouse, C. A., Whitton, J. L., Whitworth, A. J., Wileman, T., Wiley, J. W., Wilkinson, S., Willbold, D., Williams, R. L., Williamson, P. R., Wouters, B. G., Wu, C., Wu, D. C., Wu, W. K. K., Wyttenbach, A., Xavier, R. J., Xi, Z., Xia, P., Xiao, G., Xie, Z., Xie, Z., Xu, D. Z., Xu, J., Xu, L., Xu, X., Yamamoto, A., Yamamoto, A., Yamashina, S., Yamashita, M., Yan, X., Yanagida, M., Yang, D. S., Yang, E., Yang, J. M., Yang, S. Y., Yang, W., Yang, W. Y., Yang, Z., Yao, M. C., Yao, T. P., Yeganeh, B., Yen, W. L., Yin, J. J., Yin, X. M., Yoo, O. J., Yoon, G., Yoon, S. Y., Yorimitsu, T., Yoshikawa, Y., Yoshimori, T., Yoshimoto, K., You, H. J., Youle, R. J., Younes, A., Yu, L., Yu, L., Yu, S. W., Yu, W. H., Yuan, Z. M., Yue, Z., Yun, C. H., Yuzaki, M., Zabirnyk, O., Silva-Zacarin, E., David Zacks, E., Zacksenhaus, L., Zaffaroni, N., Zakeri, Z., Zeh, H. J., Zeitlin, S. O., Zhang, H., Zhang, H. L., Zhang, J., Zhang, J. P., Zhang, L., Zhang, L., Zhang, M. Y., Zhang, X. D., Zhao, M., Zhao, Y. F., Zhao, Y., Zhao, Z. J., Zheng, X., Zhivotovsky, B., Zhong, Q., Zhou, C. Z., Zhu, C., Zhu, W. G., Zhu, X. F., Zhu, X., Zhu, Y., Zoladek, T., Zong, W. X., Zorzano, A., Zschocke, J. & Zuckerbraun, B., Apr 1 2012, In: Autophagy. 8, 4, p. 445-544 100 p.

      Research output: Contribution to journal › Article › peer-review

      2944 Scopus citations

    • Inflammasome-regulated cytokines are critical mediators of acute lung injury

      Dolinay, T., Kim, Y. S., Howrylak, J., Hunninghake, G. M., An, C. H., Fredenburgh, L., Massaro, A. F., Rogers, A., Gazourian, L., Nakahira, K., Haspel, J. A., Landazury, R., Eppanapally, S., Christie, J. D., Meyer, N. J., Ware, L. B., Christiani, D. C., Ryter, S. W., Baron, R. M. & Choi, A. M. K., Jun 1 2012, In: American journal of respiratory and critical care medicine. 185, 11, p. 1225-1234 10 p.

      Research output: Contribution to journal › Article › peer-review

      Open Access
      474 Scopus citations

    • The emerging importance of autophagy in pulmonary diseases

      Mizumura, K., Cloonan, S. M., Haspel, J. A. & Choi, A. M. K., Nov 2012, In: CHEST. 142, 5, p. 1289-1299 11 p.

      Research output: Contribution to journal › Article › peer-review

      110 Scopus citations
    • 2011

      Autophagy proteins regulate innate immune responses by inhibiting the release of mitochondrial DNA mediated by the NALP3 inflammasome

      Nakahira, K., Haspel, J. A., Rathinam, V. A. K., Lee, S. J., Dolinay, T., Lam, H. C., Englert, J. A., Rabinovitch, M., Cernadas, M., Kim, H. P., Fitzgerald, K. A., Ryter, S. W. & Choi, A. M. K., Mar 2011, In: Nature immunology. 12, 3, p. 222-230 9 p.

      Research output: Contribution to journal › Article › peer-review

      Open Access
      2533 Scopus citations

    • Characterization of macroautophagic flux in vivo using a leupeptin-based assay

      Haspel, J., Shaik, R. S., Ifedigbo, E., Nakahira, K., Dolinay, T., Englert, J. A. & Choi, A. M. K., Jun 2011, In: Autophagy. 7, 6, p. 629-642 14 p.

      Research output: Contribution to journal › Article › peer-review

      Open Access
      125 Scopus citations
    • 2009

      Long-term anticoagulant therapy for idiopathic pulmonary embolism in the elderly: A decision analysis

      Haspel, J., Bauer, K., Goehler, A. & Roberts, D. H., May 1 2009, In: CHEST. 135, 5, p. 1243-1251 9 p.

      Research output: Contribution to journal › Article › peer-review

      5 Scopus citations
    • 2002

      L1 mediated homophilic binding and neurite outgrowth are modulated by alternative splicing of exon 2

      Jacob, J., Haspel, J., Kane-Goldsmith, N. & Grumet, M., 2002, In: Journal of Neurobiology. 51, 3, p. 177-189 13 p.

      Research output: Contribution to journal › Article › peer-review

      39 Scopus citations
    • 2001

      Cell adhesion molecule L1 in folded (horseshoe) and extended conformations

      Schürmann, G., Haspel, J., Grumet, M. & Erickson, H. P., 2001, In: Molecular biology of the cell. 12, 6, p. 1765-1773 9 p.

      Research output: Contribution to journal › Article › peer-review

      Open Access
      71 Scopus citations

    • Disulfide-mediated dimerization of L1 Ig domains

      Haspel, J., Schrmann, G., Jacob, J., Erickson, H. P. & Grumet, M., Nov 1 2001, In: Journal of Neuroscience Research. 66, 3, p. 347-355 9 p.

      Research output: Contribution to journal › Article › peer-review

      4 Scopus citations

    • System for cleavable Fc fusion proteins using tobacco etch virus (TEV) protease

      Haspel, J., Blanco, C., Jacob, J. & Grumet, M., 2001, In: BioTechniques. 30, 1, p. 60-66 7 p.

      Research output: Contribution to journal › Article › peer-review

      Open Access
      16 Scopus citations
    • 2000

      Fast track - Critical and optimal ig domains for promotion of neurite outgrowth by L1/Ng-CAM

      Haspel, J., Friedlander, D. R., Ivgy-May, N., Chickramane, S., Roonprapunt, C., Chen, S., Schachner, M. & Grumet, M., Feb 15 2000, In: Journal of Neurobiology. 42, 3, p. 287-302 16 p.

      Research output: Contribution to journal › Article › peer-review

      57 Scopus citations

    • Selective expression of Cre recombinase in skeletal muscle fibers

      Bothe, G. W. M., Haspel, J. A., Smith, C. L., Wiener, H. H. & Burden, S. J., Feb 2000, In: Genesis. 26, 2, p. 165-166 2 p.

      Research output: Contribution to journal › Article › peer-review

      Open Access
      126 Scopus citations
    • 1995

      raf-induced kinases may be necessary but are not sufficient for ras-p21-protein induction of oocyte maturation

      Haspel, J., Dent, P., Haystead, T., Brandt-Rauf, P. W., Chung, D., Weinstein, I. B., Nishimura, S., Yamaizumi, Z. & Pincus, M. R., 1995, In: Medical Science Research. 23, 7, p. 455-457 3 p.

      Research output: Contribution to journal › Article › peer-review

      6 Scopus citations
    • 1993

      A nickel-binding serpin, pNiXa, induces maturation of Xenopus oocytes and shows synergism with oncogenic ras-p21 protein

      Haspel, J., Sunderman, F. W., Hofper, S. M., Henjum, D. C., Brandt-Rauf, P. W., Weinstein, I. B., Nishimura, S., Yamaizumi, Z. & Pincus, M. R., 1993, In: Research Communications in Chemical Pathology and Pharmacology. 79, 2, p. 131-140 10 p.

      Research output: Contribution to journal › Article › peer-review

      22 Scopus citations
    • 1992

      A 43 kDa protein (p43) that interacts with the ras-oncogene-encoded p21 protein strongly induces maturation of oocytes

      Baskin, L., Haspel, J., O'Driscoll, K., Ronai, Z., Friedman, F. K., Brandt-Rauf, P. W., Chung, D., Weinstein, I. B., Nishimura, S., Yamaizumi, Y., Singh, G., Dykes, D. C., Murphy, R. B. & Pincus, M. R., 1992, In: Medical Science Research. 20, 22, p. 813-815 3 p.

      Research output: Contribution to journal › Article › peer-review

      4 Scopus citations

    • Inhibition of ras-oncogene-encoded p21 protein-induced maturation of oocytes by p21 peptide sequences predicted to be effector domain sites by molecular modelling

      Haspel, J., Dykes, D. C., Friedman, F. K., Robinson, R., Chung, D., Ronai, Z., Brandt-Rauf, P. W., Baskin, L., Weinstein, I. B., Nishimura, S., Yamaizumi, Y., Singh, G., Murphy, R. B. & Pincus, M. R., 1992, In: Medical Science Research. 20, 22, p. 809-811 3 p.

      Research output: Contribution to journal › Article › peer-review

      13 Scopus citations