• 7361 Citations
1991 …2020

Research output per year

If you made any changes in Pure these will be visible here soon.

Personal profile

Research interests

My clinical research interests center around diseases leading to liver transplantation and their recurrence in the transplanted liver. Thus, I am involved in clinical trials of antiviral agents used for the treatment of chronic hepatitis C. Interferon alfa and its long-acting pegylated form, in combination with ribavirin, now allow us to cure patients of a disease that is currently the leading indication for liver transplantation in the United States. Unfortunately, many patients progress to end-stage liver disease and its complications. Furthermore, infection of the transplanted liver is nearly universal, though antiviral agents are poorly tolerated and less efficacious in the transplant population. I am working, along with investigators at other centers, on studies to minimize the amount of post-transplant liver injury secondary to the hepatitis C virus. I am also studying a small group of our patients with liver allograft dysfunction following treatment with pegylated interferon and ribavirin. My other area of interest is the function of the cirrhotic liver, previously something that has been difficult to quantify. I am studying the clearance of indocyanine green as a measure of hepatocellular function in patients following placement of a transjugular intrahepatic portosystemic shunt.

Areas of Clinical Interest

Liver transplant, acute/chronic liver disease, hepatitis, cirrhosis, liver transplantation

Fingerprint Dive into the research topics where Jeffrey Crippin is active. These topic labels come from the works of this person. Together they form a unique fingerprint.

  • 11 Similar Profiles

Network Recent external collaboration on country level. Dive into details by clicking on the dots.

Research Output

  • 3 Scopus citations

    Serum alpha-fetoprotein level per total tumor volume as a predictor of recurrence of hepatocellular carcinoma after resection

    Sharma, Y., Weaver, M. J., Ludwig, D. R., Fowler, K., Vachharajani, N., Chapman, W. C. & Crippin, J. S., May 2018, In : Surgery (United States). 163, 5, p. 1002-1007 6 p.

    Research output: Contribution to journalArticle

  • 2 Scopus citations

    HBV-Associated Acute Liver Failure After Immunosuppression and Risk of Death

    Karvellas, C. J., Cardoso, F. S., Gottfried, M., Reddy, K. R., Hanje, A. J., Ganger, D., Lee, W. M., Lee, W. M., Larson, A. M., Liou, I., Fix, O., Schilsky, M., McCashland, T., Hay, J. E., Murray, N., Shaikh, A. O. S., Blei, A., Ganger, D., Zaman, A., Han, S. H. B. & 18 others, Fontana, R., McGuire, B., Chung, R. T., Smith, A., Brown, R., Crippin, J., Harrison, E., Reuben, A., Munoz, S., Reddy, R., Stravitz, R. T., Rossaro, L., Satyanarayana, R., Hassanein, T., Karvellas, C. J., Olson, J., Subramanian, R. & Hanje, J., Jan 1 2017, In : Clinical Gastroenterology and Hepatology. 15, 1, p. 113-122 10 p.

    Research output: Contribution to journalArticle

  • 12 Scopus citations

    Acute liver injury and acute liver failure from mushroom poisoning in North America

    the United States Acute Liver Failure Study Group, Jul 1 2016, In : Liver International. 36, 7, p. 1043-1050 8 p.

    Research output: Contribution to journalArticle

  • 31 Scopus citations

    Association Between Plasma Level of Galectin-9 and Survival of Patients With Drug-Induced Acute Liver Failure

    Acute Liver Failure Study Group, Apr 1 2016, In : Clinical Gastroenterology and Hepatology. 14, 4, p. 606-612.e3

    Research output: Contribution to journalArticle

  • 8 Scopus citations