• 702 Citations

Research output per year

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Personal profile

Research interests

Proteostasis and cell signaling in neurodevelopmental disorders including Angelman syndrome and autism spectrum disorders.

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Research Output

The autism-linked UBE3A T485A mutant E3 ubiquitin ligase activates the Wnt/β-catenin pathway by inhibiting the proteasome

Yi, J. J., Paranjape, S. R., Walker, M. P., Choudhury, R., Wolter, J. M., Fragola, G., Emanuele, M. J., Major, M. B. & Zylka, M. J., Jul 21 2017, In : Journal of Biological Chemistry. 292, 30, p. 12503-12515 13 p.

Research output: Contribution to journalArticle

Open Access
  • 26 Scopus citations

    Biosensors of small GTPase proteins for use in living cells and animals

    O'Shaughnessy, E. C., Yi, J. J. & Hahn, K. M., Apr 19 2016, Optical Probes in Biology. CRC Press, p. 137-166 30 p.

    Research output: Chapter in Book/Report/Conference proceedingChapter

    1 Scopus citations

    An Autism-Linked Mutation Disables Phosphorylation Control of UBE3A

    Yi, J. J., Berrios, J., Newbern, J. M., Snider, W. D., Philpot, B. D., Hahn, K. M. & Zylka, M. J., Aug 17 2015, In : Cell. 162, 4, p. 795-807 13 p., 8292.

    Research output: Contribution to journalArticle

    Open Access
  • 76 Scopus citations

    Deletion of ENTPD3 does not impair nucleotide hydrolysis in primary somatosensory neurons or spinal cord

    Zylka, M., McCoy, E., Street, S., Taylor-Blake, B., Yi, J., Edwards, M. & Wightman, M., Sep 19 2014, In : F1000Research. 3, 4563.2.

    Research output: Contribution to journalArticle

    Open Access
  • 2 Scopus citations

    Dissecting motility signaling through activation of specific Src-effector complexes

    Karginov, A. V., Tsygankov, D., Berginski, M., Chu, P. H., Trudeau, E. D., Yi, J. J., Gomez, S., Elston, T. C. & Hahn, K. M., Apr 2014, In : Nature Chemical Biology. 10, 4, p. 286-290 5 p.

    Research output: Contribution to journalArticle

  • 31 Scopus citations