At the Weber Lab, we conduct cutting-edge research in cancer biology. Our team of undergraduate students, PhD graduate students, postdocs, technicians, staff scientists, and junior faculty members is dedicated to advancing the understanding of cancer through innovative research and discovery. With backgrounds in molecular biology, biochemistry, cell biology, genetics, oncology, and biomedical engineering, our team is committed to pursuing innovative solutions to the most pressing challenges in cancer biology. Our state-of-the-art facilities are equipped with the latest technologies and instrumentation to support cutting-edge research in cancer biology. Several ongoing projects in the lab include:

1. The collaboration of the ARF and p53 tumor suppressors in preventing triple-negative breast cancer
2. Identifying drivers of triple-negative breast cancer in African American women
3. Design and fabrication of novel microfluidic devices to model lymphatics in breast cancer metastasis
4. Functional interaction of ADAR1 and MDM2 oncogenes in ferroptosis
5. Restoration of ARF tumor suppressor function through peptide mimics
6. Using high-throughput DNA-barcoded chemical libraries to screen for oncogene inhibitors
7. Studying the mechanism of dsRNA sensing and IFN pathway activation in cancer

• Lab Website

I have trained 16 PhD graduate students, 2 MSTP students, 12 postdoctoral researchers, and 49 undergraduate research students, 12 of which were underrepresented minorities in my 23 years at Washington University. I am also the head of the new American Cancer Society Diversity Internship in Cancer Research Program that provides summer research opportunities to underrepresented Washington University undergrads and the American Cancer Society Diversity Post-baccalaureate program.