Jason Hassenstab

Associate Professor of Neurology, Associate Professor of Psychological & Brain Sciences

    • 2905 Citations

    Research output per year

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    Personal profile

    Research interests

    Jason Hassenstab, PhD, is an Associate Professor of Neurology and of Psychological and Brain Sciences and the director of the Cognitive Technology Research Laboratory (CTRLab) at Washington University in St. Louis. He also leads the Cognition Cores for the Dominantly-Inherited Alzheimer Network-Trials Unit (DIAN-TU) and the DIAN observational study and the Charles F. and Joanne Knight Alzheimer’s Disease Research Center. The CTRLab’s focus in on using technology to improve cognitive assessments in Alzheimer’s disease and other disorders. We use measurement burst designs, based on principles from ecological momentary assessment, to measure cognition rapidly and frequently on smartphones in normal and clinical populations. We also develop web-based cognitive assessments designed to be sensitive to the very earliest stages of neurodegenerative disease. Dr. Hassenstab has been continuously funded by the NIH since 2007 and also receives funding from foundations. His most recent projects include development of the Ambulatory Research in Cognition (ARC) smartphone application for the DIAN observational study, the DIAN-TU Phase III clinical trials, and the Healthy Aging and Senile Dementia program project grant at the Knight ADRC. Prior to pursuing academics, Dr. Hassenstab toured internationally as a professional jazz saxophonist, often sporting a purple pinstriped zoot suit, and made hundreds of dollars. He completed a bachelor’s degree in Jazz and Contemporary Music Performance at New York University and a PhD in psychology under mentorship of Dr. Antonio Convit at New York University and Fordham University. He then completed a Fellowship at Brown University and joined the faculty at Washington University in St. Louis in 2010.

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    Research Output

    • 2905 Citations
    • 74 Article
    • 3 Review article
    • 2 Chapter

    Amyloid and Tau Pathology Associations With Personality Traits, Neuropsychiatric Symptoms, and Cognitive Lifestyle in the Preclinical Phases of Sporadic and Autosomal Dominant Alzheimer's Disease

    Dominantly Inherited Alzheimer Network (DIAN) & PREVENT-AD Research Group, 2020, (Accepted/In press) In : Biological Psychiatry.

    Research output: Contribution to journalArticle

  • 1 Scopus citations

    A soluble phosphorylated tau signature links tau, amyloid and the evolution of stages of dominantly inherited Alzheimer’s disease

    the Dominantly Inherited Alzheimer Network, Mar 1 2020, In : Nature medicine. 26, 3, p. 398-407 10 p.

    Research output: Contribution to journalArticle

  • 18 Scopus citations

    Awareness of genetic risk in the Dominantly Inherited Alzheimer Network (DIAN)

    Dominantly Inherited Alzheimer Network, Jan 1 2020, In : Alzheimer's and Dementia. 16, 1, p. 219-228 10 p.

    Research output: Contribution to journalArticle

    Open Access
  • Cognitive trajectory in mild cognitive impairment due to primary age-related tauopathy

    Teylan, M., Mock, C., Gauthreaux, K., Chen, Y. C., Chan, K. C. G., Hassenstab, J., Besser, L. M., Kukull, W. A. & Crary, J. F., Jan 1 2020, In : Brain. 143, 2, p. 611-621 11 p.

    Research output: Contribution to journalArticle

  • 1 Scopus citations

    Enabling Technologies for Personalized and Precision Medicine

    Ho, D., Quake, S. R., McCabe, E. R. B., Chng, W. J., Chow, E. K., Ding, X., Gelb, B. D., Ginsburg, G. S., Hassenstab, J., Ho, C. M., Mobley, W. C., Nolan, G. P., Rosen, S. T., Tan, P., Yen, Y. & Zarrinpar, A., May 2020, In : Trends in Biotechnology. 38, 5, p. 497-518 22 p.

    Research output: Contribution to journalReview article

  • 3 Scopus citations