Research Output per year
Research Output per year
Personal profile
Research interests
Our laboratory focuses on understanding how Taspase1 and MLL regulate critical biological pathways with a special emphasis on cancer biology. Specifically, we’d like to utilize combined biochemical and genetic approaches to investigate how the evolutionarily conserved protease, Taspase1, and its substrates such as MLL coordinate essential cellular and developmental processes.
Areas of Clinical Interest
Kidney cancer, rare kidney cancer, targeted therapy, immunotherapy, precision medicine
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Research Output
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Elective Cytoreductive Nephrectomy After Checkpoint Inhibitor Immunotherapy in Patients With Initially Unresectable Metastatic Clear Cell Renal Cell Carcinoma
Reimers, M. A., Figenshau, R. S., Kim, E. H., Tucker, J., Kasten, N., Khan, A. S., Hanneken, J. M., Smith, Z. L. & Hsieh, J. J., Oct 2020, In: Clinical Genitourinary Cancer. 18, 5, p. 361-366 6 p.Research output: Contribution to journal › Article › peer-review
2 Scopus citations -
Erratum: Integrated Proteogenomic Characterization of Clear Cell Renal Cell Carcinoma (Cell (2019) 179(4) (964–983.e31), (S0092867419311237), (10.1016/j.cell.2019.10.007))
Clinical Proteomic Tumor Analysis Consortium, Jan 9 2020, In: Cell. 180, 1, p. 207 1 p.Research output: Contribution to journal › Comment/debate
Open Access3 Scopus citations -
Exploiting the circuit breaker cancer evolution model in human clear cell renal cell carcinoma
Hsieh, J. J. & Cheng, E. H., Aug 2020, In: Cell Stress. 4, 8, p. 191-198 8 p.Research output: Contribution to journal › Article › peer-review
Open Access -
Laparoscopic cytoreductive nephrectomy is associated with significantly improved survival compared with open cytoreductive nephrectomy or targeted therapy alone
Zhao, K., Kim, E. H., Vetter, J. M., Hsieh, J., Venkatesh, R., Bhayani, S. B. & Sherburne Figenshau, R., Dec 2020, In: Molecular and Clinical Oncology. 13, 6, p. 1-4 4 p., 71.Research output: Contribution to journal › Article › peer-review
Open Access -
Modeling biological and genetic diversity in upper tract urothelial carcinoma with patient derived xenografts
Kim, K., Hu, W., Audenet, F., Almassi, N., Hanrahan, A. J., Murray, K., Bagrodia, A., Wong, N., Clinton, T. N., Dason, S., Mohan, V., Jebiwott, S., Nagar, K., Gao, J., Penson, A., Hughes, C., Gordon, B., Chen, Z., Dong, Y., Watson, P. A. & 17 others, , Dec 1 2020, In: Nature communications. 11, 1, 1975.Research output: Contribution to journal › Article › peer-review
Open Access1 Scopus citations