Research output per year
Research output per year
Personal profile
Research interests
Jai Rudra's lab is interested in the development of nano-scale biomaterials such as nanofibers, nanoparticles, virus-like particles, and hydrogels for engaging the immune system to induce protective antibody and cell-mediated immune responses against diseases such as tuberculosis, melanoma and flavivirus infections (West Nile and Zika). His is also investigating the development of vaccines against drugs of addiction such as cocaine.
Biomaterials immunoengineering is a multidisciplinary field that lies at the intersection of materials science, chemistry, immunology and vaccinology. His lab collaborates with virologists, immunologists, and clinicians not only to develop synthetic vaccination platforms but also to understand how biomaterials interact with the immune system and continue to develop novel materials and creative tools to tackle multidisciplinary problems in vaccine development and immunotherapy.
Available to Mentor:
- PhD Students
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Collaborations and top research areas from the last five years
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Correction: Peptide nanofibers and PAMP agonist combinations enhance pulmonary CD4+T cell functionality of immune recall to vaccination (Journal of Nanobiotechnology, (2026), 24, 1, (414), 10.1186/s12951-026-04305-5)
Files, M. A., Das, A., Kim, D., Buck, J., Endsley, J. J. & Rudra, J. S., Dec 2026, In: Journal of Nanobiotechnology. 24, 1, 444.Research output: Contribution to journal › Comment/debate
Open Access -
Peptide nanofibers and PAMP agonist combinations enhance pulmonary CD4+T cell functionality of immune recall to vaccination
Files, M. A., Das, A., Kim, D., Buck, J., Endsley, J. J. & Rudra, J. S., Dec 2026, In: Journal of Nanobiotechnology. 24, 1, 414.Research output: Contribution to journal › Article › peer-review
Open Access -
Stereoselective Coassembly of Chiral Isomer Peptide Pairs
O’Neill, C. L., Fascetti, J. L., Clapacs, Z., Kaplita, L. K., Liu, C. Y., Kim, D., White, M. A. & Rudra, J. S., May 13 2026, In: ACS Materials Au. 6, 3, p. 529-538 10 p.Research output: Contribution to journal › Article › peer-review
Open Access1 Link opens in a new tab Scopus citations -
Substituent-Based Modulation of Self-Assembly and Immunogenicity of Amphipathic Peptides
Das, A., Pramanik, U., Brown, E. M., Liu, C. Y., Gong, H., Fascetti, J., Gibson, M., Stealey, S., Zustiak, S. P., Berkland, C., Sharma, P., Jackrel, M. E., White, M. A. & Rudra, J. S., Mar 27 2026, In: Advanced Science. 13, 18, e18567.Research output: Contribution to journal › Article › peer-review
Open Access3 Link opens in a new tab Scopus citations -
Histidine-rich enantiomeric peptide coacervates enhance antigen sequestration and presentation to T cells
Pramanik, U., Das, A., Brown, E. M., Struckman, H. L., Wang, H., Stealey, S., Sprunger, M. L., Wasim, A., Fascetti, J., Mondal, J., Silva, J. R., Zustiak, S. P., Jackrel, M. E. & Rudra, J. S., Mar 25 2025, In: Chemical Science. 16, 17, p. 7523-7536 14 p.Research output: Contribution to journal › Article › peer-review
Open Access9 Link opens in a new tab Scopus citations