Jae-Sung Kim

2024

Tenovin-1, a Selective SIRT1/2 Inhibitor, Attenuates High-fat Diet-induced Hepatic Fibrosis via Inhibition of HSC Activation in ZDF Rats

Sharma, S., Gali, S., Kundu, A., Park, J. H., Kim, J. S. & Kim, H. S., 2024, In: International Journal of Biological Sciences. 20, 9, p. 3334-3352 19 p.

Research output: Contribution to journal › Article › peer-review

Open Access

2 Scopus citations

2023

Normothermic Machine Perfusion for Declined Livers: A Strategy to Rescue Marginal Livers for Transplantation

RESTORE Investigators Group, Apr 1 2023, In: Journal of the American College of Surgeons. 236, 4, p. 614-625 12 p.

Research output: Contribution to journal › Article › peer-review

19 Scopus citations

Protective effect of dendropanoxide against cadmium-induced hepatotoxicity via anti-inflammatory activities in Sprague-Dawley rats

Gali, S., Sharma, S., Kundu, A., Lee, E., Han, J. H., Shin, J. K., Choi, J. S., Kyung, S. Y., Kim, J. S. & Kim, H. S., 2023, In: Toxicology Mechanisms and Methods. 33, 6, p. 437-451 15 p.

Research output: Contribution to journal › Article › peer-review

4 Scopus citations

2021

A novel multidrug combination mitigates rat liver steatosis through activating ampk pathway during normothermic machine perfusion

Xu, M., Zhou, F., Ahmed, O., Upadhya, G. A., Jia, J., Lee, C., Xing, J., Ye, L., Hee Shim, S., Zhang, Z., Byrnes, K., Wong, B., Kim, J. S., Lin, Y. & Chapman, W. C., Nov 1 2021, In: Transplantation. 105, 11, p. E215-E225

Research output: Contribution to journal › Article › peer-review

Open Access

12 Scopus citations

Critical roles of calpastatin in ischemia/reperfusion injury in aged livers

Flores-Toro, J., Chun, S. K., Shin, J. K., Campbell, J., Lichtenberger, M., Chapman, W., Zendejas, I., Behrns, K., Leeuwenburgh, C. & Kim, J. S., Aug 2021, In: Cells. 10, 8, 1863.

Research output: Contribution to journal › Article › peer-review

Open Access

10 Scopus citations

Cytoprotection of rat hepatocytes by desipramine in a model of simulated ischemia/reperfusion

Shin, J. K. & Kim, J. S., Sep 2021, In: Biochemistry and Biophysics Reports. 27, 101075.

Research output: Contribution to journal › Article › peer-review

Open Access

3 Scopus citations

Dual Lactate Clearance in the Viability Assessment of Livers Donated After Circulatory Death With Ex Situ Normothermic Machine Perfusion

Xu, M., Zhou, F., Ahmed, O., Randle, L. V., Shin, J. K., Zhu, Y., Upadhya, G. A., Byrnes, K., Wong, B., Kim, J. S., Lin, Y. & Chapman, W. C., Nov 17 2021, In: Transplantation Direct. 7, 12, p. E789

Research output: Contribution to journal › Article › peer-review

Open Access

5 Scopus citations

Sesquiterpene Alcohol Cedrol Chemosensitizes Human Cancer Cells and Suppresses Cell Proliferation by Destabilizing Plasma Membrane Lipid Rafts

Mishra, S. K., Bae, Y. S., Lee, Y. M., Kim, J. S., Oh, S. H. & Kim, H. M., Jan 21 2021, In: Frontiers in Cell and Developmental Biology. 8, 571676.

Research output: Contribution to journal › Article › peer-review

Open Access

25 Scopus citations

2018

Carbon Monoxide Inhibits Islet Apoptosis via Induction of Autophagy

Kim, D. S., Song, L., Wang, J., Wu, H., Gou, W., Cui, W., Kim, J. S. & Wang, H., May 10 2018, In: Antioxidants and Redox Signaling. 28, 14, p. 1309-1322 14 p.

Research output: Contribution to journal › Article › peer-review

Open Access

27 Scopus citations

Gα12 overexpression induced by miR16 dysregulation contributes to liver fibrosis by promoting autophagy in hepatic stellate cells

Kim, K. M., Han, C. Y., Kim, J. Y., Cho, S. S., Kim, Y. S., Koo, J. H., Lee, J. M., Lim, S. C., Kang, K. W., Kim, J. S., Hwang, S. J., Ki, S. H. & Kim, S. G., Mar 2018, In: Journal of Hepatology. 68, 3, p. 493-504 12 p.

Research output: Contribution to journal › Article › peer-review

88 Scopus citations

Loss of sirtuin 1 and mitofusin 2 contributes to enhanced ischemia/reperfusion injury in aged livers

Chun, S. K., Lee, S., Flores-Toro, J., Rebecca Y., U., Yang, M. J., Go, K. L., Biel, T. G., Miney, C. E., Pierre Louis, S., Law, B. K., Law, M. E., Thomas, E. M., Behrns, K. E., Leeuwenburgh, C. & Kim, J. S., Aug 2018, In: Aging Cell. 17, 4, e12761.

Research output: Contribution to journal › Article › peer-review

Open Access

60 Scopus citations

2017

Exercise-induced autophagy in fatty liver disease

Chun, S. K., Lee, S., Yang, M. J., Leeuwenburgh, C. & Kim, J. S., Jul 1 2017, In: Exercise and Sport Sciences Reviews. 45, 3, p. 181-186 6 p.

Research output: Contribution to journal › Article › peer-review

26 Scopus citations

Magnetic Targeting of Stem Cell Derivatives Enhances Hepatic Engraftment into Structurally Normal Liver

Fagg, W. S., Liu, N., Yang, M. J., Cheng, K., Chung, E., Kim, J. S., Wu, G. & Fair, J., Dec 1 2017, In: Cell Transplantation. 26, 12, p. 1868-1877 10 p.

Research output: Contribution to journal › Article › peer-review

Open Access

8 Scopus citations

Mitochondrial ATP transporter depletion protects mice against liver steatosis and insulin resistance

Cho, J., Zhang, Y., Park, S. Y., Joseph, A. M., Han, C., Park, H. J., Kalavalapalli, S., Chun, S. K., Morgan, D., Kim, J. S., Someya, S., Mathews, C. E., Lee, Y. J., Wohlgemuth, S. E., Sunny, N. E., Lee, H. Y., Choi, C. S., Shiratsuchi, T., Oh, S. P. & Terada, N., Feb 16 2017, In: Nature communications. 8, 14477.

Research output: Contribution to journal › Article › peer-review

Open Access

49 Scopus citations

2016

Autophagy in ischemic livers: A critical role of sirtuin 1/mitofusin 2 axis in autophagy induction

Chun, S. K., Go, K., Yang, M. J., Zendejas, I., Behrns, K. E. & Kim, J. S., 2016, In: Toxicological Research. 32, 1, p. 35-46 12 p.

Research output: Contribution to journal › Article › peer-review

Open Access

18 Scopus citations

CUB domain-containing protein 1 and the epidermal growth factor receptor cooperate to induce cell detachment

Law, M. E., Ferreira, R. B., Davis, B. J., Higgins, P. J., Kim, J. S., Castellano, R. K., Chen, S., Luesch, H. & Law, B. K., Aug 5 2016, In: Breast Cancer Research. 18, 1, 80.

Research output: Contribution to journal › Article › peer-review

Open Access

22 Scopus citations

Sirtuin 1 suppresses mitochondrial dysfunction of ischemic mouse livers in a mitofusin 2-dependent manner

Biel, T. G., Lee, S., Flores-Toro, J. A., Dean, J. W., Go, K. L., Lee, M. H., Law, B. K., Law, M. E., Dunn, W. A., Zendejas, I., Behrns, K. E. & Kim, J. S., Feb 1 2016, In: Cell Death and Differentiation. 23, 2, p. 279-290 12 p.

Research output: Contribution to journal › Article › peer-review

Open Access

92 Scopus citations

2015

Mitochondrial ATP transporter Ant2 depletion impairs erythropoiesis and B lymphopoiesis

Cho, J., Seo, J., Lim, C. H., Yang, L., Shiratsuchi, T., Lee, M. H., Chowdhury, R. R., Kasahara, H., Kim, J. S., Oh, S. P., Lee, Y. J. & Terada, N., Sep 11 2015, In: Cell Death and Differentiation. 22, 9, p. 1437-1450 14 p.

Research output: Contribution to journal › Article › peer-review

Open Access

38 Scopus citations

Mitochondrial Dysfunction and Autophagy in Hepatic Ischemia/Reperfusion Injury

Go, K. L., Lee, S., Zendejas, I., Behrns, K. E. & Kim, J. S., 2015, In: BioMed Research International. 2015, 183469.

Research output: Contribution to journal › Article › peer-review

Open Access

106 Scopus citations

SLC39A14 Is Required for the Development of Hepatocellular Iron Overload in Murine Models of Hereditary Hemochromatosis

Jenkitkasemwong, S., Wang, C. Y., Coffey, R., Zhang, W., Chan, A., Biel, T., Kim, J. S., Hojyo, S., Fukada, T. & Knutson, M. D., Jul 7 2015, In: Cell metabolism. 22, 1, p. 138-150 13 p.

Research output: Contribution to journal › Article › peer-review

Open Access

196 Scopus citations

2014

A novel ATG4B antagonist inhibits autophagy and has a negative impact on osteosarcoma tumors

Akin, D., Wang, S. K., Habibzadegah-Tari, P., Law, B., Ostrov, D., Li, M., Yin, X. M., Kim, J. S., Horenstein, N. & Dunn, W. A., Nov 1 2014, In: Autophagy. 10, 11, p. 2021-2035 15 p.

Research output: Contribution to journal › Article › peer-review

Open Access

203 Scopus citations

Mitophagy: Therapeutic potentials for liver disease and beyond

Lee, S. & Kim, J. S., 2014, In: Toxicological Research. 30, 4, p. 243-250 8 p.

Research output: Contribution to journal › Article › peer-review

Open Access

23 Scopus citations

Role of autophagy in differential sensitivity of hepatocarcinoma cells to sorafenib

Fischer, T. D., Wang, J. H., Vlada, A., Kim, J. S. & Behrns, K. E., 2014, In: World Journal of Hepatology. 6, 10, p. 752-758 7 p.

Research output: Contribution to journal › Article › peer-review

Open Access

34 Scopus citations

2013

Carbamazepine suppresses calpain-mediated autophagy impairment after ischemia/reperfusion in mouse livers

Kim, J. S., Wang, J. H., Biel, T. G., Kim, D. S., Flores-Toro, J. A., Vijayvargiya, R., Zendejas, I. & Behrns, K. E., Dec 15 2013, In: Toxicology and Applied Pharmacology. 273, 3, p. 600-610 11 p.

Research output: Contribution to journal › Article › peer-review

Open Access

41 Scopus citations

Glucocorticoids and histone deacetylase inhibitors cooperate to block the invasiveness of basal-like breast cancer cells through novel mechanisms

Law, M. E., Corsino, P. E., Jahn, S. C., Davis, B. J., Chen, S., Patel, B., Pham, K., Lu, J., Sheppard, B., Nørgaard, P., Hong, J., Higgins, P., Kim, J. S., Luesch, H. & Law, B. K., Mar 7 2013, In: Oncogene. 32, 10, p. 1316-1329 14 p.

Research output: Contribution to journal › Article › peer-review

Open Access

68 Scopus citations

Neutral sphingomyelinase 2 modulates cytotoxic effects of protopanaxadiol on different human cancer cells

Park, B., Lee, Y. M., Kim, J. S., Her, Y., Kang, J. H., Oh, S. H. & Kim, H. M., Jul 27 2013, In: BMC Complementary and Alternative Medicine. 13, 194.

Research output: Contribution to journal › Article › peer-review

Open Access

21 Scopus citations

Upregulated autophagy protects cardiomyocytes from oxidative stress-induced toxicity

Dutta, D., Xu, J., Kim, J. S., Dunn, W. A. & Leeuwenburgh, C., Mar 2013, In: Autophagy. 9, 3, p. 328-344 17 p.

Research output: Contribution to journal › Article › peer-review

Open Access

126 Scopus citations

2012

Guidelines for the use and interpretation of assays for monitoring autophagy

Klionsky, D. J., Abdalla, F. C., Abeliovich, H., Abraham, R. T., Acevedo-Arozena, A., Adeli, K., Agholme, L., Agnello, M., Agostinis, P., Aguirre-Ghiso, J. A., Ahn, H. J., Ait-Mohamed, O., Ait-Si-Ali, S., Akematsu, T., Akira, S., Al-Younes, H. M., Al-Zeer, M. A., Albert, M. L., Albin, R. L. & Alegre-Abarrategui, J. & 1,249 others, Aleo, M. F., Alirezaei, M., Almasan, A., Almonte-Becerril, M., Amano, A., Amaravadi, R., Amarnath, S., Amer, A. O., Andrieu-Abadie, N., Anantharam, V., Ann, D. K., Anoopkumar-Dukie, S., Aoki, H., Apostolova, N., Arancia, G., Aris, J. P., Asanuma, K., Asare, N. Y. O., Ashida, H., Askanas, V., Askew, D. S., Auberger, P., Baba, M., Backues, S. K., Baehrecke, E. H., Bahr, B. A., Bai, X. Y., Bailly, Y., Baiocchi, R., Baldini, G., Balduini, W., Ballabio, A., Bamber, B. A., Bampton, E. T. W., Bánhegyi, G., Bartholomew, C. R., Bassham, D. C., Bast, R. C., Batoko, H., Bay, B. H., Beau, I., Béchet, D. M., Begley, T. J., Behl, C., Behrends, C., Bekri, S., Bellaire, B., Bendall, L. J., Benetti, L., Berliocchi, L., Bernardi, H., Bernassola, F., Besteiro, S., Bhatia-Kissova, I., Bi, X., Biard-Piechaczyk, M., Blum, J. S., Boise, L. H., Bonaldo, P., Boone, D. L., Bornhauser, B. C., Bortoluci, K. R., Bossis, I., Bost, F., Bourquin, J. P., Boya, P., Boyer-Guittaut, M., Bozhkov, P. V., Brady, N. R., Brancolini, C., Brech, A., Brenman, J. E., Brennand, A., Bresnick, E. H., Brest, P., Bridges, D., Bristol, M. L., Brookes, P. S., Brown, E. J., Brumell, J. H., Brunetti-Pierri, N., Brunk, U. T., Bulman, D. E., Bultman, S. J., Bultynck, G., Burbulla, L. F., Bursch, W., Butchar, J. P., Buzgariu, W., Bydlowski, S. P., Cadwell, K., Cahová, M., Cai, D., Cai, J., Cai, Q., Calabretta, B., Calvo-Garrido, J., Camougrand, N., Campanella, M., Campos-Salinas, J., Candi, E., Cao, L., Caplan, A. B., Carding, S. R., Cardoso, S. M., Carew, J. S., Carlin, C. R., Carmignac, V., Carneiro, L. A. M., Carra, S., Caruso, R. A., Casari, G., Casas, C., Castino, R., Cebollero, E., Cecconi, F., Celli, J., Chaachouay, H., Chae, H. J., Chai, C. Y., Chan, D. C., Chan, E. Y., Chang, R. C. C., Che, C. M., Chen, C. C., Chen, G. C., Chen, G. Q., Chen, M., Chen, Q., Chen, S. S. L., Chen, W. L., Chen, X., Chen, X., Chen, X., Chen, Y. G., Chen, Y., Chen, Y., Chen, Y. J., Chen, Z., Cheng, A., Cheng, C. H. K., Cheng, Y., Cheong, H., Cheong, J. H., Cherry, S., Chess-Williams, R., Cheung, Z. H., Chevet, E., Chiang, H. L., Chiarelli, R., Chiba, T., Chin, L. S., Chiou, S. H., Chisari, F. V., Cho, C. H., Cho, D. H., Choi, A. M. K., Choi, D. S., Choi, K. S., Choi, M. E., Chouaib, S., Choubey, D., Choubey, V., Chu, C. T., Chuang, T. H., Chueh, S. H., Chun, T., Chwae, Y. J., Chye, M. L., Ciarcia, R., Ciriolo, M. R., Clague, M. J., Clark, R. S. B., Clarke, P. G. H., Clarke, R., Codogno, P., Coller, H. A., Colombo, M. I., Comincini, S., Condello, M., Condorelli, F., Cookson, M. R., Coombs, G. H., Coppens, I., Corbalan, R., Cossart, P., Costelli, P., Costes, S., Coto-Montes, A., Couve, E., Coxon, F. P., Cregg, J. M., Crespo, J. L., Cronjé, M. J., Cuervo, A. M., Cullen, J. J., Czaja, M. J., D'Amelio, M., Darfeuille-Michaud, A., Davids, L. M., Davies, F. E., De Felici, M., De Groot, J. F., De Haan, C. A. M., De Martino, L., De Milito, A., De Tata, V., Debnath, J., Degterev, A., Dehay, B., Delbridge, L. M. D., Demarchi, F., Deng, Y. Z., Dengjel, J., Dent, P., Denton, D., Deretic, V., Desai, S. D., Devenish, R. J., Di Gioacchino, M., Di Paolo, G., Di Pietro, C., Díaz-Araya, G., Díaz-Laviada, I., Diaz-Meco, M. T., Diaz-Nido, J., Dikic, I., Dinesh-Kumar, S. P., Ding, W. X., Distelhorst, C. W., Diwan, A., Djavaheri-Mergny, M., Dokudovskaya, S., Dong, Z., Dorsey, F. C., Dosenko, V., Dowling, J. J., Doxsey, S., Dreux, M., Drew, M. E., Duan, Q., Duchosal, M. A., Duff, K., Dugail, I., Durbeej, M., Duszenko, M., Edelstein, C. L., Edinger, A. L., Egea, G., Eichinger, L., Eissa, N. T., Ekmekcioglu, S., El-Deiry, W. S., Elazar, Z., Elgendy, M., Ellerby, L. M., Er Eng, K., Engelbrecht, A. M., Engelender, S., Erenpreisa, J., Escalante, R., Esclatine, A., Eskelinen, E. L., Espert, L., Espina, V., Fan, H., Fan, J., Fan, Q. W., Fan, Z., Fang, S., Fang, Y., Fanto, M., Fanzani, A., Farkas, T., Farré, J. C., Faure, M., Fechheimer, M., Feng, C. G., Feng, J., Feng, Q., Feng, Y., Fésüs, L., Feuer, R., Figueiredo-Pereira, M. E., Fimia, G. M., Fingar, D. C., Finkbeiner, S., Finkel, T., Finley, K. D., Fiorito, F., Fisher, E. A., Fisher, P. B., Flajolet, M., Florez-McClure, M. L., Florio, S., Fon, E. A., Fornai, F., Fortunato, F., Fotedar, R., Fowler, D. H., Fox, H. S., Franco, R., Frankel, L. B., Fransen, M., Fuentes, J. M., Fueyo, J., Fujii, J., Fujisaki, K., Fujita, E., Fukuda, M., Furukawa, R. H., Gaestel, M., Gailly, P., Gajewska, M., Galliot, B., Galy, V., Ganesh, S., Ganetzky, B., Ganley, I. G., Gao, F. B., Gao, G. F., Gao, J., Garcia, L., Garcia-Manero, G., Garcia-Marcos, M., Garmyn, M., Gartel, A. L., Gatti, E., Gautel, M., Gawriluk, T. R., Gegg, M. E., Geng, J., Germain, M., Gestwicki, J. E., Gewirtz, D. A., Ghavami, S., Ghosh, P., Giammarioli, A. M., Giatromanolaki, A. N., Gibson, S. B., Gilkerson, R. W., Ginger, M. L., Ginsberg, H. N., Golab, J., Goligorsky, M. S., Golstein, P., Gomez-Manzano, C., Goncu, E., Gongora, C., Gonzalez, C. D., Gonzalez, R., González-Estévez, C., González-Polo, R. A., Gonzalez-Rey, E., Gorbunov, N. V., Gorski, S., Goruppi, S., Gottlieb, R. A., Gozuacik, D., Granato, G. E., Grant, G. D., Green, K. N., Gregorc, A., Gros, F., Grose, C., Grunt, T. W., Gual, P., Guan, J. L., Guan, K. L., Guichard, S. M., Gukovskaya, A. S., Gukovsky, I., Gunst, J., Gustafsson, A. B., Halayko, A. J., Hale, A. N., Halonen, S. K., Hamasaki, M., Han, F., Han, T., Hancock, M. K., Hansen, M., Harada, H., Harada, M., Hardt, S. E., Harper, J. W., Harris, A. L., Harris, J., Harris, S. D., Hashimoto, M., Haspel, J. A., Hayashi, S. I., Hazelhurst, L. A., He, C., He, Y. W., Hébert, M. J., Heidenreich, K. A., Helfrich, M. H., Helgason, G. V., Henske, E. P., Herman, B., Herman, P. K., Hetz, C., Hilfiker, S., Hill, J. A., Hocking, L. J., Hofman, P., Hofmann, T. G., Höhfeld, J., Holyoake, T. L., Hong, M. H., Hood, D. A., Hotamisligil, G. S., Houwerzijl, E. J., Høyer-Hansen, M., Hu, B., Hu, C. A. A., Hu, H. M., Hua, Y., Huang, C., Huang, J., Huang, S., Huang, W. P., Huber, T. B., Huh, W. K., Hung, T. H., Hupp, T. R., Hur, G. M., Hurley, J. B., Hussain, S. N. A., Hussey, P. J., Hwang, J. J., Hwang, S., Ichihara, A., Ilkhanizadeh, S., Inoki, K., Into, T., Iovane, V., Iovanna, J. L., Ip, N. Y., Isaka, Y., Ishida, H., Isidoro, C., Isobe, K. I., Iwasaki, A., Izquierdo, M., Izumi, Y., Jaakkola, P. M., Jäättelä, M., Jackson, G. R., Jackson, W. T., Janji, B., Jendrach, M., Jeon, J. H., Jeung, E. B., Jiang, H., Jiang, H., Jiang, J. X., Jiang, M., Jiang, Q., Jiang, X., Jiménez, A., Jin, M., Jin, S., Joe, C. O., Johansen, T., Johnson, D. E., Johnson, G. V. W., Jones, N. L., Joseph, B., Joseph, S. K., Joubert, A. M., Juhász, G., Juillerat-Jeanneret, L., Jung, C. H., Jung, Y. K., Kaarniranta, K., Kaasik, A., Kabuta, T., Kadowaki, M., Kagedal, K., Kamada, Y., Kaminskyy, V. O., Kampinga, H. H., Kanamori, H., Kang, C., Kang, K. B., Il Kang, K., Kang, R., Kang, Y. A., Kanki, T., Kanneganti, T. D., Kanno, H., Kanthasamy, A. G., Kanthasamy, A., Karantza, V., Kaushal, G. P., Kaushik, S., Kawazoe, Y., Ke, P. Y., Kehrl, J. H., Kelekar, A., Kerkhoff, C., Kessel, D. H., Khalil, H., Kiel, J. A. K. W., Kiger, A. A., Kihara, A., Kim, D. R., Kim, D. H., Kim, D. H., Kim, E. K., Kim, H. R., Kim, J. S., Kim, J. H., Kim, J. C., Kim, J. K., Kim, P. K., Kim, S. W., Kim, Y. S., Kim, Y., Kimchi, A., Kimmelman, A. C., King, J. S., Kinsella, T. J., Kirkin, V., Kirshenbaum, L. A., Kitamoto, K., Kitazato, K., Klein, L., Klimecki, W. T., Klucken, J., Knecht, E., Ko, B. C. B., Koch, J. C., Koga, H., Koh, J. Y., Koh, Y. H., Koike, M., Komatsu, M., Kominami, E., Kong, H. J., Kong, W. J., Korolchuk, V. I., Kotake, Y., Koukourakis, M. I., Kouri Flores, J. B., Kovács, A. L., Kraft, C., Krainc, D., Krämer, H., Kretz-Remy, C., Krichevsky, A. M., Kroemer, G., Krüger, R., Krut, O., Ktistakis, N. T., Kuan, C. Y., Kucharczyk, R., Kumar, A., Kumar, R., Kumar, S., Kundu, M., Kung, H. J., Kurz, T., Kwon, H. J., La Spada, A. R., Lafont, F., Lamark, T., Landry, J., Lane, J. D., Lapaquette, P., Laporte, J. F., László, L., Lavandero, S., Lavoie, J. N., Layfield, R., Lazo, P. A., Le, W., Le Cam, L., Ledbetter, D. J., Lee, A. J. X., Lee, B. W., Lee, G. M., Lee, J., Lee, J. H., Lee, M., Lee, M. S., Lee, S. H., Leeuwenburgh, C., Legembre, P., Legouis, R., Lehmann, M., Lei, H. Y., Lei, Q. Y., Leib, D. A., Leiro, J., Lemasters, J. J., Lemoine, A., Lesniak, M. S., Lev, D., Levenson, V. V., Levine, B., Levy, E., Li, F., Li, J. L., Li, L., Li, S., Li, W., Li, X. J., Li, Y. B., Li, Y. P., Liang, C., Liang, Q., Liao, Y. F., Liberski, P. P., Lieberman, A., Lim, H. J., Lim, K. L., Lim, K., Lin, C. F., Lin, F. C., Lin, J., Lin, J. D., Lin, K., Lin, W. W., Lin, W. C., Lin, Y. L., Linden, R., Lingor, P., Lippincott-Schwartz, J., Lisanti, M. P., Liton, P. B., Liu, B., Liu, C. F., Liu, K., Liu, L., Liu, Q. A., Liu, W., Liu, Y. C., Liu, Y., Lockshin, R. A., Lok, C. N., Lonial, S., Loos, B., Lopez-Berestein, G., López-Otín, C., Lossi, L., Lotze, M. T., Lõw, P., Lu, B., Lu, B., Lu, B., Lu, Z., Luciano, F., Lukacs, N. W., Lund, A. H., Lynch-Day, M. A., Ma, Y., Macian, F., MacKeigan, J. P., Macleod, K. F., Madeo, F., Maiuri, L., Maiuri, M. C., Malagoli, D., Malicdan, M. C. V., Malorni, W., Man, N., Mandelkow, E. M., Manon, S., Manov, I., Mao, K., Mao, X., Mao, Z., Marambaud, P., Marazziti, D., Marcel, Y. L., Marchbank, K., Marchetti, P., Marciniak, S. 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X., Zorzano, A., Zschocke, J. & Zuckerbraun, B., Apr 1 2012, In: Autophagy. 8, 4, p. 445-544 100 p.

Research output: Contribution to journal › Article › peer-review

2949 Scopus citations

Mitochondrial permeability transition in rat hepatocytes after anoxia/reoxygenation: Role of Ca ²⁺-dependent mitochondrial formation of reactive oxygen species

Kim, J. S., Wang, J. H. & Lemasters, J. J., Apr 1 2012, In: American Journal of Physiology - Gastrointestinal and Liver Physiology. 302, 7, p. G723-G731

Research output: Contribution to journal › Article › peer-review

Open Access

75 Scopus citations

2011

Autophagy suppresses age-dependent ischemia and reperfusion injury in livers of mice

Wang, J., Ahn, I., Fischer, T. D., Byeon, J., Dunn, W. A., Behrns, K. E., Leeuwenburgh, C. & Kim, J., Dec 2011, In: Gastroenterology. 141, 6, p. 2188-2199.e6

Research output: Contribution to journal › Article › peer-review

Open Access

129 Scopus citations

2010

Inhibition of the mitochondrial permeability transition by protein kinase A in rat liver mitochondria and hepatocytes

Pediaditakis, P., Kim, J. S., He, L., Zhang, X., Graves, L. M. & Lemasters, J. J., Nov 1 2010, In: Biochemical Journal. 431, 3, p. 411-421 11 p.

Research output: Contribution to journal › Article › peer-review

26 Scopus citations

Lysosomal Iron mobilization and induction of the mitochondrial permeability transition in acetaminophen-induced toxicity to mouse hepatocytes

Kon, K., Kim, J. S., Uchiyama, A., Jaeschke, H. & Lemasters, J. J., Jun 27 2010, In: Toxicological Sciences. 117, 1, p. 101-108 8 p.

Research output: Contribution to journal › Article › peer-review

Open Access

92 Scopus citations

The emerging role of iron dyshomeostasis in the mitochondrial decay of aging

Xu, J., Marzetti, E., Seo, A. Y., Kim, J. S., Prolla, T. A. & Leeuwenburgh, C., Jul 2010, In: Mechanisms of Ageing and Development. 131, 7-8, p. 487-493 7 p.

Research output: Contribution to journal › Article › peer-review

Open Access

66 Scopus citations

2009

Heat shock protein 90 inhibition abrogates hepatocellular cancer growth through cdc2-mediated G₂/M cell cycle arrest and apoptosis

Watanabe, G., Behrns, K. E., Kim, J. S. & Kim, R. D., Jul 2009, In: Cancer Chemotherapy and Pharmacology. 64, 3, p. 433-443 11 p.

Research output: Contribution to journal › Article › peer-review

Open Access

27 Scopus citations

2008

Impaired autophagy: A mechanism of mitochondrial dysfunction in anoxic rat hepatocytes

Kim, J. S., Nitta, T., Mohuczy, D., O'Malley, K. A., Moldawer, L. L., Dunn, W. A. & Behrns, K. E., May 2008, In: Hepatology. 47, 5, p. 1725-1736 12 p.

Research output: Contribution to journal › Article › peer-review

177 Scopus citations

Murine cirrhosis induces hepatocyte epithelial mesenchymal transition and alterations in survival signaling pathways

Nitta, T., Kim, J. S., Mohuczy, D. & Behrns, K. E., Sep 2008, In: Hepatology. 48, 3, p. 909-919 11 p.

Research output: Contribution to journal › Article › peer-review

Open Access

147 Scopus citations

Translocation of iron from lysosomes into mitochondria is a key event during oxidative stress-induced hepatocellular injury

Uchiyama, A., Kim, J. S., Kon, K., Jaeschke, H., Ikejima, K., Watanabe, S. & Lemasters, J. J., Nov 2008, In: Hepatology. 48, 5, p. 1644-1654 11 p.

Research output: Contribution to journal › Article › peer-review

136 Scopus citations

2007

Transforming growth factor beta mediates hepatocyte apoptosis through Smad3 generation of reactive oxygen species

Black, D., Lyman, S., Qian, T., Lemasters, J. J., Rippe, R. A., Nitta, T., Kim, J. S. & Behrns, K. E., Dec 2007, In: Biochimie. 89, 12, p. 1464-1473 10 p.

Research output: Contribution to journal › Article › peer-review

Open Access

47 Scopus citations

2006

Basal reactive oxygen species determine the susceptibility to apoptosis in cirrhotic hepatocytes

Raval, J., Lyman, S., Nitta, T., Mohuczy, D., Lemasters, J. J., Kim, J. S. & Behrns, K. E., Dec 1 2006, In: Free Radical Biology and Medicine. 41, 11, p. 1645-1654 10 p.

Research output: Contribution to journal › Article › peer-review

Open Access