Personal profile
Research interests
Understanding the cellular and molecular mechanisms underlying B cell responses to vaccination and infection. Of particular interest is understanding durability of protective immunity and studying mechanisms of induction of broadly protective responses to rapidly evolving pathogens, such as influenza viruses.
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Collaborations and top research areas from the last five years
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Germinal center–mediated broadening of B cell responses to SARS-CoV-2 booster immunization
Malladi, S. K., Jaiswal, D., Ying, B., Alsoussi, W. B., Darling, T. L., Dadonaite, B., Civljak, A., Horvath, S. C., Zhou, J. Q., Kim, W., Turner, J. S., Schmitz, A. J., Han, F., Scheaffer, S. M., Farnsworth, C. W., Nachbagauer, R., Nestorova, B., Chalkias, S., Klebert, M. K. & Edwards, D. K. & 10 others, , Oct 2025, In: Science immunology. 10, 112, eadu4107.Research output: Contribution to journal › Article › peer-review
Open Access1 Link opens in a new tab Scopus citations -
Identification of a seasonal influenza vaccine-induced broadly protective neuraminidase antibody
Madsen, A., Okba, N. M. A., Pholcharee, T., Matz, H. C., Lv, H., Ibanez Trullen, M., Zhou, J. Q., Turner, J. S., Schmitz, A. J., Han, F., Horvath, S. C., Malladi, S. K., Krammer, F., Wu, N. C. & Ellebedy, A. H., Jun 2 2025, In: The Journal of experimental medicine. 222, 6Research output: Contribution to journal › Article › peer-review
Open Access5 Link opens in a new tab Scopus citations -
Monoclonal antibodies targeting the FimH adhesin protect against uropathogenic E. coli UTI
Lopatto, E. D. B., Santiago-Borges, J. M., Sanick, D. A., Malladi, S. K., Azimzadeh, P. N., Timm, M. W., Fox, I. F., Schmitz, A. J., Turner, J. S., Sayed Ahmed, S. M., Ortinau, L., Gualberto, N. C., Pinkner, J. S., Dodson, K. W., Ellebedy, A. H., Kau, A. L. & Hultgren, S. J., Jun 20 2025, In: Science Advances. 11, 25, eadw0698.Research output: Contribution to journal › Article › peer-review
Open Access10 Link opens in a new tab Scopus citations -
CD4+ T cells exhibit distinct transcriptional phenotypes in the lymph nodes and blood following mRNA vaccination in humans
Borcherding, N., Kim, W., Quinn, M., Han, F., Zhou, J. Q., Sturtz, A. J., Schmitz, A. J., Lei, T., Schattgen, S. A., Klebert, M. K., Suessen, T., Middleton, W. D., Goss, C. W., Liu, C., Crawford, J. C., Thomas, P. G., Teefey, S. A., Presti, R. M., O’Halloran, J. A. & Turner, J. S. & 2 others, , Sep 2024, In: Nature immunology. 25, 9, p. 1731-1741 11 p.Research output: Contribution to journal › Article › peer-review
Open Access17 Link opens in a new tab Scopus citations -
Immunoglobulin replacement products protect against SARS-CoV-2 infection in vivo despite poor neutralizing activity
Zimmerman, O., Altman Doss, A. M., Ying, B., Liang, C. Y., Mackin, S. R., Davis-Adams, H. G., Adams, L. J., VanBlargan, L. A., Chen, R. E., Scheaffer, S. M., Desai, P., Raju, S., Mantia, T. L., O’Shaughnessy, C. C., Monroy, J. M., James Wedner, H., Rigell, C. J., Kau, A. L., Dy, T. B. & Ren, Z. & 7 others, , Feb 8 2024, In: JCI Insight. 9, 3, e176359.Research output: Contribution to journal › Article › peer-review
Open Access7 Link opens in a new tab Scopus citations