Jacco Boon

Associate Professor of Medicine, Associate Professor of Molecular Microbiology, Associate Professor of Pathology and Immunology

    • 2515 Citations

    Research output per year

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    Personal profile

    Research interests

    Influenza viruses are a major threat to human health causing annual epidemics and occasional pandemics. Our goal is to identify risk factors associated with severe disease. Specifically we are interested in discovering novel virus and host proteins that contribute to severe infections. This important information will be used to develop novel antiviral therapies targeting these proteins to prevent disease following influenza virus infection.


    • COVID-19

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    Research Output

    • 2515 Citations
    • 49 Article
    • 3 Review article
    • 1 Chapter
    • 1 Comment/debate

    Influenza virus repurposes the antiviral protein IFIT2 to promote translation of viral mRNAs

    Tran, V., Ledwith, M. P., Thamamongood, T., Higgins, C. A., Tripathi, S., Chang, M. W., Benner, C., García-Sastre, A., Schwemmle, M., Boon, A. C. M., Diamond, M. S. & Mehle, A., 2020, (Accepted/In press) In : Nature microbiology.

    Research output: Contribution to journalArticle

  • Disruption of Type III interferon (IFN) genes Ifnl2 and Ifnl3 recapitulates loss of the Type III IFN receptor in the mucosal antiviral response

    Peterson, S. T., Kennedy, E. A., Brigleb, P. H., Taylor, G. M., Urbanek, K., Bricker, T. L., Lee, S., Shin, H., Dermody, T. S., Boon, A. C. M. & Baldridge, M. T., Nov 1 2019, In : Journal of virology. 93, 22, e01073-19.

    Research output: Contribution to journalArticle

  • 4 Scopus citations

    Influenza pathogenesis: The effect of host factors on severity of disease

    Gounder, A. P. & Boon, A. C. M., Jan 15 2019, In : Journal of Immunology. 202, 2, p. 341-350 10 p.

    Research output: Contribution to journalReview article

  • 9 Scopus citations

    RNA Sequence Features Are at the Core of Influenza A Virus Genome Packaging

    Shafiuddin, M. & Boon, A. C. M., Oct 4 2019, In : Journal of Molecular Biology. 431, 21, p. 4217-4228 12 p.

    Research output: Contribution to journalReview article

  • 2 Scopus citations

    Therapeutic efficacy of favipiravir against bourbon virus in mice

    Bricker, T. L., Shafiuddin, M., Gounder, A. P., Janowski, A. B., Zhao, G., Williams, G. D., Jagger, B. W., Diamondid, M. S., Bailey, T., Kwon, J. H., Wangid, D. & Boon, A. C. M., Jun 2019, In : PLoS pathogens. 15, 6, e1007790.

    Research output: Contribution to journalArticle

    Open Access
  • 4 Scopus citations