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Personal profile

Research interests

Influenza viruses are a major threat to human health causing annual epidemics and occasional pandemics. Our goal is to identify risk factors associated with severe disease. Specifically we are interested in discovering novel virus and host proteins that contribute to severe infections. This important information will be used to develop novel antiviral therapies targeting these proteins to prevent disease following influenza virus infection.

Keywords

  • COVID-19

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  • Defining the risk of SARS-CoV-2 variants on immune protection

    DeGrace, M. M., Ghedin, E., Frieman, M. B., Krammer, F., Grifoni, A., Alisoltani, A., Alter, G., Amara, R. R., Baric, R. S., Barouch, D. H., Bloom, J. D., Bloyet, L. M., Bonenfant, G., Boon, A. C. M., Boritz, E. A., Bratt, D. L., Bricker, T. L., Brown, L., Buchser, W. J., Carreño, J. M., & 110 othersCohen-Lavi, L., Darling, T. L., Davis-Gardner, M. E., Dearlove, B. L., Di, H., Dittmann, M., Doria-Rose, N. A., Douek, D. C., Drosten, C., Edara, V. V., Ellebedy, A., Fabrizio, T. P., Ferrari, G., Fischer, W. M., Florence, W. C., Fouchier, R. A. M., Franks, J., García-Sastre, A., Godzik, A., Gonzalez-Reiche, A. S., Gordon, A., Haagmans, B. L., Halfmann, P. J., Ho, D. D., Holbrook, M. R., Huang, Y., James, S. L., Jaroszewski, L., Jeevan, T., Johnson, R. M., Jones, T. C., Joshi, A., Kawaoka, Y., Kercher, L., Koopmans, M. P. G., Korber, B., Koren, E., Koup, R. A., LeGresley, E. B., Lemieux, J. E., Liebeskind, M. J., Liu, Z., Livingston, B., Logue, J. P., Luo, Y., McDermott, A. B., McElrath, M. J., Meliopoulos, V. A., Menachery, V. D., Montefiori, D. C., Mühlemann, B., Munster, V. J., Munt, J. E., Nair, M. S., Netzl, A., Niewiadomska, A. M., O’Dell, S., Pekosz, A., Perlman, S., Pontelli, M. C., Rockx, B., Rolland, M., Rothlauf, P. W., Sacharen, S., Scheuermann, R. H., Schmidt, S. D., Schotsaert, M., Schultz-Cherry, S., Seder, R. A., Sedova, M., Sette, A., Shabman, R. S., Shen, X., Shi, P. Y., Shukla, M., Simon, V., Stumpf, S., Sullivan, N. J., Thackray, L. B., Theiler, J., Thomas, P. G., Trifkovic, S., Türeli, S., Turner, S. A., Vakaki, M. A., van Bakel, H., VanBlargan, L. A., Vincent, L. R., Wallace, Z. S., Wang, L., Wang, M., Wang, P., Wang, W., Weaver, S. C., Webby, R. J., Weiss, C. D., Wentworth, D. E., Weston, S. M., Whelan, S. P. J., Whitener, B. M., Wilks, S. H., Xie, X., Ying, B., Yoon, H., Zhou, B., Hertz, T., Smith, D. J., Diamond, M. S., Post, D. J. & Suthar, M. S., May 26 2022, In: Nature. 605, 7911, p. 640-652 13 p.

    Research output: Contribution to journalReview articlepeer-review

    Open Access
    15 Scopus citations
  • Detection of Bourbon Virus-Specific Serum Neutralizing Antibodies in Human Serum in Missouri, USA

    Bamunuarachchi, G., Harastani, H., Rothlauf, P. W., Dai, Y. N., Ellebedy, A., Fremont, D., Whelan, S. P. J., Wang, D. & Boon, A. C. M., Jun 2022, In: mSphere. 7, 3

    Research output: Contribution to journalArticlepeer-review

    Open Access
  • Egg-Derived Anti-SARS-CoV-2 Immunoglobulin Y (IgY) With Broad Variant Activity as Intranasal Prophylaxis Against COVID-19

    Frumkin, L. R., Lucas, M., Scribner, C. L., Ortega-Heinly, N., Rogers, J., Yin, G., Hallam, T. J., Yam, A., Bedard, K., Begley, R., Cohen, C. A., Badger, C. V., Abbasi, S. A., Dye, J. M., McMillan, B., Wallach, M., Bricker, T. L., Joshi, A., Boon, A. C. M., Pokhrel, S., & 6 othersKraemer, B. R., Lee, L., Kargotich, S., Agochiya, M., John, T. S. & Mochly-Rosen, D., Jun 1 2022, In: Frontiers in immunology. 13, 899617.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    1 Scopus citations
  • Open Access
    2 Scopus citations
  • JIB-04 Has Broad-Spectrum Antiviral Activity and Inhibits SARS-CoV-2 Replication and Coronavirus Pathogenesis

    Son, J., Huang, S., Zeng, Q., Bricker, T. L., Case, J. B., Zhou, J., Zang, R., Liu, Z., Chang, X., Darling, T. L., Xu, J., Harastani, H. H., Chen, L., Castro, M. F. G., Zhao, Y., Kohio, H. P., Hou, G., Fan, B., Niu, B., Guo, R., & 11 othersRothlauf, P. W., Bailey, A. L., Wang, X., Shi, P. Y., Martinez, E. D., Brody, S. L., Whelan, S. P. J., Diamond, M. S., Boon, A. C. M., Li, B. & Ding, S., Feb 1 2022, In: mBio. 13, 1, e03377.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    2 Scopus citations