• 1087 Citations
19992020

Research output per year

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Personal profile

Research interests

We are working on developing Big Data and Machine Learning methods devoted transform data into knowledge, and knowledge into person-centered actionable knowledge. This methods are able to agnostic ally deal with knowledge bases of complex diseases in highly uncertain, vague, and co-morbid environments. We applied our methods to genetics, images, personality traits and real-time clinical signals from ICU environments.

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Research Output

Uncovering the complex genetics of human character

Zwir, I., Arnedo, J., Del-Val, C., Pulkki-Råback, L., Konte, B., Yang, S. S., Romero-Zaliz, R., Hintsanen, M., Cloninger, K. M., Garcia, D., Svrakic, D. M., Rozsa, S., Martinez, M., Lyytikäinen, L. P., Giegling, I., Kähönen, M., Hernandez-Cuervo, H., Seppälä, I., Raitoharju, E., de Erausquin, G. A. & 7 others, Raitakari, O., Rujescu, D., Postolache, T. T., Sung, J., Keltikangas-Järvinen, L., Lehtimäki, T. & Cloninger, C. R., Oct 1 2020, In : Molecular Psychiatry. 25, 10, p. 2295-2312 18 p.

Research output: Contribution to journalArticle

Open Access
  • 20 Scopus citations

    Uncovering the complex genetics of human personality: response from authors on the PGMRA Model

    Zwir, I., Mishra, P., Del-Val, C., Gu, C. C., de Erausquin, G. A., Lehtimäki, T. & Cloninger, C. R., Oct 1 2020, In : Molecular Psychiatry. 25, 10, p. 2210-2213 4 p.

    Research output: Contribution to journalLetter

    Open Access
    3 Scopus citations

    Uncovering the complex genetics of human temperament

    Zwir, I., Arnedo, J., Del-Val, C., Pulkki-Råback, L., Konte, B., Yang, S. S., Romero-Zaliz, R., Hintsanen, M., Cloninger, K. M., Garcia, D., Svrakic, D. M., Rozsa, S., Martinez, M., Lyytikäinen, L. P., Giegling, I., Kähönen, M., Hernandez-Cuervo, H., Seppälä, I., Raitoharju, E., de Erausquin, G. A. & 7 others, Raitakari, O., Rujescu, D., Postolache, T. T., Sung, J., Keltikangas-Järvinen, L., Lehtimäki, T. & Cloninger, C. R., Oct 1 2020, In : Molecular Psychiatry. 25, 10, p. 2275-2294 20 p.

    Research output: Contribution to journalArticle

    Open Access
  • 15 Scopus citations

    Uncovering tumour heterogeneity through PKR and nc886 analysis in metastatic colon cancer patients treated with 5-FU-based chemotherapy

    Ortega-García, M. B., Mesa, A., Moya, E. L. J., Rueda, B., Lopez-Ordoño, G., García, J. Á., Conde, V., Redondo-Cerezo, E., Lopez-Hidalgo, J. L., Jiménez, G., Peran, M., Martínez-González, L. J., Val, C. D., Zwir, I., Marchal, J. A. & García, M. Á., Feb 2020, In : Cancers. 12, 2, 379.

    Research output: Contribution to journalArticle

    Open Access
  • 4 Scopus citations

    The complex genetics and biology of human temperament: a review of traditional concepts in relation to new molecular findings

    Cloninger, C. R., Cloninger, K. M., Zwir, I. & Keltikangas-Järvinen, L., Dec 1 2019, In : Translational psychiatry. 9, 1, 290.

    Research output: Contribution to journalReview article

    Open Access
  • 5 Scopus citations