Igor Dmitriev

2024

Correction to: Mucosal vaccine-induced cross-reactive CD8+ T cells protect against SARS-CoV-2 XBB.1.5 respiratory tract infection (Nature Immunology, (2024), 25, 3, (537-551), 10.1038/s41590-024-01743-x)

Ying, B., Darling, T. L., Desai, P., Liang, C. Y., Dmitriev, I. P., Soudani, N., Bricker, T., Kashentseva, E. A., Harastani, H., Raju, S., Liu, M., Schmidt, A. G., Curiel, D. T., Boon, A. C. M. & Diamond, M. S., Mar 2024, In: Nature immunology. 25, 3, p. 578 1 p.

Research output: Contribution to journal › Comment/debate

Open Access

1 Scopus citations

Mucosal adenovirus vaccine boosting elicits IgA and durably prevents XBB.1.16 infection in nonhuman primates

Gagne, M., Flynn, B. J., Andrew, S. F., Marquez, J., Flebbe, D. R., Mychalowych, A., Lamb, E., Davis-Gardner, M. E., Burnett, M. R., Serebryannyy, L. A., Lin, B. C., Ziff, Z. E., Maule, E., Carroll, R., Naisan, M., Jethmalani, Y., Pessaint, L., Todd, J. P. M., Doria-Rose, N. A. & Case, J. B. & 28 others, Dmitriev, I. P., Kashentseva, E. A., Ying, B., Dodson, A., Kouneski, K., O’Dell, S., Wali, B., Ellis, M., Godbole, S., Laboune, F., Henry, A. R., Teng, I. T., Wang, D., Wang, L., Zhou, Q., Zouantchangadou, S., Van Ry, A., Lewis, M. G., Andersen, H., Kwong, P. D., Curiel, D. T., Roederer, M., Nason, M. C., Foulds, K. E., Suthar, M. S., Diamond, M. S., Douek, D. C. & Seder, R. A., Oct 2024, In: Nature immunology. 25, 10, p. 1913-1927 15 p.

Research output: Contribution to journal › Article › peer-review

Open Access

11 Scopus citations

Mucosal vaccine-induced cross-reactive CD8⁺ T cells protect against SARS-CoV-2 XBB.1.5 respiratory tract infection

Ying, B., Darling, T. L., Desai, P., Liang, C. Y., Dmitriev, I. P., Soudani, N., Bricker, T., Kashentseva, E. A., Harastani, H., Raju, S., Liu, M., Schmidt, A. G., Curiel, D. T., Boon, A. C. M. & Diamond, M. S., Mar 2024, In: Nature immunology. 25, 3, p. 537-551 15 p.

Research output: Contribution to journal › Article › peer-review

Open Access

17 Scopus citations

Nonreciprocity in CHIKV and MAYV Vaccine-Elicited Protection

Weber, W. C., Andoh, T. F., Kreklywich, C. N., Streblow, Z. J., Denton, M., Streblow, M. M., Powers, J. M., Sulgey, G., Medica, S., Dmitriev, I., Curiel, D. T., Haese, N. N. & Streblow, D. N., Sep 2024, In: Vaccines. 12, 9, 970.

Research output: Contribution to journal › Article › peer-review

Open Access

1 Scopus citations

Retraction Notice to: Inhibition of Multiple Protective Signaling Pathways and Ad.5/3 Delivery Enhances mda-7/IL-24 Therapy of Malignant Glioma (Molecular Therapy (2010) 18(6) (1130–1142), (S1525001616310528), (10.1038/mt.2010.29))

Hamed, H. A., Yacoub, A., Park, M. A., Eulitt, P. J., Dash, R., Sarkar, D., Dmitriev, I. P., Lesniak, M. S., Shah, K., Grant, S., Curiel, D. T., Fisher, P. B. & Dent, P., Dec 4 2024, In: Molecular Therapy. 32, 12, p. 4524 1 p.

Research output: Contribution to journal › Comment/debate

2023

Adenoviral vectors infect B lymphocytes in vivo

Rice-Boucher, P. J., Mendonça, S. A., Alvarez, A. B., Sturtz, A. J., Lorincz, R., Dmitriev, I. P., Kashentseva, E. A., Lu, Z. H., Romano, R., Selby, M., Pingale, K. & Curiel, D., Sep 6 2023, In: Molecular Therapy. 31, 9, p. 2600-2611 12 p.

Research output: Contribution to journal › Article › peer-review

Open Access

4 Scopus citations

Engineering a Novel Modular Adenoviral mRNA Delivery Platform Based on Tag/Catcher Bioconjugation

Geng, K., Rice-Boucher, P. J., Kashentseva, E. A., Dmitriev, I. P., Lu, Z. H., Goedegebuure, S. P., Gillanders, W. E. & Curiel, D. T., Nov 2023, In: Viruses. 15, 11, 2277.

Research output: Contribution to journal › Article › peer-review

Open Access

1 Scopus citations

Retraction Notice to: Insulin-like Growth Factor-binding Protein-7 (IGFBP7): A Promising Gene Therapeutic for Hepatocellular Carcinoma (HCC) (Molecular Therapy (2013) 21(4) (758–766), (S1525001616306499), (10.1038/mt.2012.282))

Chen, D., Siddiq, A., Emdad, L., Rajasekaran, D., Gredler, R., Shen, X. N., Santhekadur, P. K., Srivastava, J., Robertson, C. L., Dmitriev, I., Kashentseva, E. A., Curiel, D. T., Fisher, P. B. & Sarkar, D., Feb 1 2023, In: Molecular Therapy. 31, 2, p. 599 1 p.

Research output: Contribution to journal › Comment/debate

Open Access

2022

Efficient Genome Editing Achieved via Plug-and-Play Adenovirus Piggyback Transport of Cas9/gRNA Complex on Viral Capsid Surface

Lu, Z. H., Li, J., Dmitriev, I. P., Kashentseva, E. A. & Curiel, D. T., Jul 26 2022, In: ACS nano. 16, 7, p. 10443-10455 13 p.

Research output: Contribution to journal › Article › peer-review

Open Access

8 Scopus citations

2021

Advanced genetic engineering to achieve in vivo targeting of adenovirus utilizing camelid single domain antibody

Lee, M., Lu, Z. H., Shoemaker, C. B., Tremblay, J. M., St. Croix, B., Seaman, S., Gonzalez-Pastor, R., Kashentseva, E. A., Dmitriev, I. P. & Curiel, D. T., Jun 10 2021, In: Journal of Controlled Release. 334, p. 106-113 8 p.

Research output: Contribution to journal › Article › peer-review

Open Access

6 Scopus citations

An intranasal vaccine durably protects against SARS-CoV-2 variants in mice

Hassan, A. O., Shrihari, S., Gorman, M. J., Ying, B., Yaun, D., Raju, S., Chen, R. E., Dmitriev, I. P., Kashentseva, E., Adams, L. J., Mann, C., Davis-Gardner, M. E., Suthar, M. S., Shi, P. Y., Saphire, E. O., Fremont, D. H., Curiel, D. T., Alter, G. & Diamond, M. S., Jul 27 2021, In: Cell Reports. 36, 4, 109452.

Research output: Contribution to journal › Article › peer-review

Open Access

98 Scopus citations

Evaluation of tumor immunity after administration of conditionally replicative adenoviral vector in canine osteosarcoma patients

Agarwal, P., Gammon, E. A., Sandey, M., Lindley, S. S., Koehler, J. W., Matz, B. M., Smith, A. N., Kashentseva, E. A., Dmitriev, I. P., Curiel, D. T. & Smith, B. F., Feb 2021, In: Heliyon. 7, 2, e06210.

Research output: Contribution to journal › Article › peer-review

Open Access

5 Scopus citations

2020

A new gorilla adenoviral vector with natural lung tropism avoids liver toxicity and is amenable to capsid engineering and vector retargeting

Lu, Z. H., Dmitriev, I. P., Brough, D. E., Kashentseva, E. A., Li, J. & Curiel, D. T., May 1 2020, In: Journal of virology. 94, 10, e00265-20.

Research output: Contribution to journal › Article › peer-review

Open Access

9 Scopus citations

A Single-Dose Intranasal ChAd Vaccine Protects Upper and Lower Respiratory Tracts against SARS-CoV-2

Hassan, A. O., Kafai, N. M., Dmitriev, I. P., Fox, J. M., Smith, B. K., Harvey, I. B., Chen, R. E., Winkler, E. S., Wessel, A. W., Case, J. B., Kashentseva, E., McCune, B. T., Bailey, A. L., Zhao, H., VanBlargan, L. A., Dai, Y. N., Ma, M., Adams, L. J., Shrihari, S. & Danis, J. E. & 11 others, Gralinski, L. E., Hou, Y. J., Schäfer, A., Kim, A. S., Keeler, S. P., Weiskopf, D., Baric, R. S., Holtzman, M. J., Fremont, D. H., Curiel, D. T. & Diamond, M. S., Oct 1 2020, In: Cell. 183, 1, p. 169-184.e13

Research output: Contribution to journal › Article › peer-review

Open Access

446 Scopus citations

Targeting tumor neoangiogenesis via targeted adenoviral vector to achieve effective cancer gene therapy for disseminated neoplastic disease

Lee, M., Lu, Z. H., Li, J., Kashentseva, E. A., Dmitriev, I. P., Mendonca, S. A. & Curiel, D. T., Mar 2020, In: Molecular Cancer Therapeutics. 19, 3, p. 966-971 6 p.

Research output: Contribution to journal › Article › peer-review

Open Access

6 Scopus citations

2019

A Gorilla Adenovirus-Based Vaccine against Zika Virus Induces Durable Immunity and Confers Protection in Pregnancy

Hassan, A. O., Dmitriev, I. P., Kashentseva, E. A., Zhao, H., Brough, D. E., Fremont, D. H., Curiel, D. T. & Diamond, M. S., Sep 3 2019, In: Cell Reports. 28, 10, p. 2634-2646.e4

Research output: Contribution to journal › Article › peer-review

Open Access

20 Scopus citations

Defining a murine ovarian cancer model for the evaluation of conditionally-replicative adenovirus (CRAd) virotherapy agents

González-Pastor, R., Ashshi, A. M., El-Shemi, A. G., Dmitriev, I. P., Kashentseva, E. A., Lu, Z. H., Goedegebuure, S. P., Podhajcer, O. L. & Curiel, D. T., Feb 15 2019, In: Journal of Ovarian Research. 12, 1, 18.

Research output: Contribution to journal › Article › peer-review

Open Access

8 Scopus citations

Vaccine-induced skewing of t cell responses protects against chikungunya virus disease

Broeckel, R. M., Haese, N., Ando, T., Dmitriev, I., Kreklywich, C. N., Powers, J., Denton, M., Smith, P., Morrison, T. E., Heise, M., Defilippis, V., Messaoudi, I., Curiel, D. T. & Streblow, D. N., 2019, In: Frontiers in immunology. 10, OCT, 2563.

Research output: Contribution to journal › Article › peer-review

Open Access

18 Scopus citations

2018

Development of an adenovirus vector vaccine platform for targeting dendritic cells

Sharma, P. K., Dmitriev, I. P., Kashentseva, E. A., Raes, G., Li, L., Kim, S. W., Lu, Z. H., Arbeit, J. M., Fleming, T. P., Kaliberov, S. A., Goedegebuure, S. P., Curiel, D. T. & Gillanders, W. E., Feb 1 2018, In: Cancer gene therapy. 25, 1-2, p. 27-38 12 p.

Research output: Contribution to journal › Article › peer-review

Open Access

30 Scopus citations

Improved induction of anti-melanoma T cells by adenovirus-5/3 fiber modification to target human DCs

Chondronasiou, D., Eisden, T. J. T. H. D., Stam, A. G. M., Matthews, Q. L., Icyuz, M., Hooijberg, E., Dmitriev, I., Curiel, D. T., de Gruijl, T. D. & van de Ven, R., Sep 2018, In: Vaccines. 6, 3, 42.

Research output: Contribution to journal › Article › peer-review

Open Access

7 Scopus citations

Inclusion of the murine IgGκ signal peptide increases the cellular immunogenicity of a simian adenoviral vectored Plasmodium vivax multistage vaccine

Fonseca, J. A., McCaffery, J. N., Caceres, J., Kashentseva, E., Singh, B., Dmitriev, I. P., Curiel, D. T. & Moreno, A., May 11 2018, In: Vaccine. 36, 20, p. 2799-2808 10 p.

Research output: Contribution to journal › Article › peer-review

Open Access

17 Scopus citations

2017

Adenovirus platform enhances transduction efficiency of human mesenchymal stem cells: An opportunity for cellular carriers of targeted TRAIL-based TR3 biologics in ovarian cancer

Kuroki, L. M., Jin, X., Dmitriev, I. P., Kashentseva, E. A., Powell, M. A., Mutch, D. G., Dietz, A. B., Curiel, D. T., Hawkins, W. G. & Spitzer, D., Dec 2017, In: PloS one. 12, 12, e0190125.

Research output: Contribution to journal › Article › peer-review

Open Access

16 Scopus citations

A prime-boost immunization regimen based on a simian adenovirus 36 vectored multi-stage malaria vaccine induces protective immunity in mice

Fonseca, J. A., McCaffery, J. N., Kashentseva, E., Singh, B., Dmitriev, I. P., Curiel, D. T. & Moreno, A., May 31 2017, In: Vaccine. 35, 24, p. 3239-3248 10 p.

Research output: Contribution to journal › Article › peer-review

Open Access

9 Scopus citations

Correction: Apogossypol derivative BI-97C1 (Sabutoclax) targeting Mcl-1 sensitizes prostate cancer cells to mda-7/IL-24-mediated toxicity (Proceedings of the National Academy of Sciences of the United States of America (2011) 108 (8785-8790) DOI: 10.1073/pnas.1100769108)

Dash, R., Azab, B., Quinn, B. A., Shen, X., Wang, X. Y., Das, S. K., Rahmani, M., Wei, J., Hedvat, M., Dent, P., Dmitriev, I. P., Curiel, D. T., Grant, S., Wu, B., Stebbins, J. L., Pellecchia, M., Reed, J. C., Sarkar, D. & Fisher, P. B., May 30 2017, In: Proceedings of the National Academy of Sciences of the United States of America. 114, 22, p. E4522-E4523

Research output: Contribution to journal › Comment/debate

Open Access

2016

Adenoviral Expression of a Bispecific VHH-Based Neutralizing Agent That Targets Protective Antigen Provides Prophylactic Protection from Anthrax in Mice

Moayeri, M., Tremblay, J. M., Debatis, M., Dmitriev, I. P., Kashentseva, E. A., Yeh, A. J., Cheung, G. Y. C., Curiel, D. T., Leppla, S. & Shoemaker, C. B., Mar 2016, In: Clinical and Vaccine Immunology. 23, 3, p. 213-218 6 p.

Research output: Contribution to journal › Article › peer-review

Open Access

19 Scopus citations

A plasmodium promiscuous T cell epitope delivered within the Ad5 hexon protein enhances the protective efficacy of a protein based malaria vaccine

Fonseca, J. A., Cabrera-Mora, M., Kashentseva, E. A., Villegas, J. P., Fernandez, A., Van Pelt, A., Dmitriev, I. P., Curiel, D. T. & Moreno, A., Apr 2016, In: PloS one. 11, 4, e0154819.

Research output: Contribution to journal › Article › peer-review

Open Access

10 Scopus citations

A recombinant chimeric Ad5/3 vector expressing a multistage plasmodium antigen induces protective immunity in mice using heterologous prime-boost immunization regimens

Cabrera-Mora, M., Fonseca, J. A., Singh, B., Zhao, C., Makarova, N., Dmitriev, I., Curiel, D. T., Blackwell, J. & Moreno, A., Oct 1 2016, In: Journal of Immunology. 197, 7, p. 2748-2761 14 p.

Research output: Contribution to journal › Article › peer-review

Open Access

10 Scopus citations

A tetraspecific VHH-based neutralizing antibody modifies disease outcome in three animal models of clostridium difficile infection

Schmidt, D. J., Beamer, G., Tremblay, J. M., Steele, J. A., Kim, H. B., Wang, Y., Debatis, M., Sun, X., Kashentseva, E. A., Dmitriev, I. P., Curiel, D. T., Shoemaker, C. B. & Tzipori, S., Sep 2016, In: Clinical and Vaccine Immunology. 23, 9, p. 774-784 11 p.

Research output: Contribution to journal › Article › peer-review

Open Access

37 Scopus citations

Combinatorial strategies based on CRAd-IL24 and CRAd-ING4 virotherapy with anti-angiogenesis treatment for ovarian cancer

Ashshi, A. M., El-Shemi, A. G., Dmitriev, I. P., Kashentseva, E. A. & Curiel, D. T., Jun 27 2016, In: Journal of Ovarian Research. 9, 1, 38.

Research output: Contribution to journal › Article › peer-review

Open Access

12 Scopus citations

Erratum: Membrane-proximal TRAIL species are incapable of inducing short circuit apoptosis signaling: Implications for drug development and basic cytokine biology

Tatzel, K., Kuroki, L., Dmitriev, I., Kashentseva, E., Curiel, D. T., Goedegebuure, S. P., Powell, M. A., Mutch, D. G., Hawkins, W. G. & Spitzer, D., May 4 2016, In: Scientific reports. 6, 25217.

Research output: Contribution to journal › Comment/debate

Open Access

2 Scopus citations

Membrane-proximal TRAIL species are incapable of inducing short circuit apoptosis signaling: Implications for drug development and basic cytokine biology

Tatzel, K., Kuroki, L., Dmitriev, I., Kashentseva, E., Curiel, D. T., Goedegebuure, S. P., Powell, M. A., Mutch, D. G., Hawkins, W. G. & Spitzer, D., Mar 3 2016, In: Scientific reports. 6, 22661.

Research output: Contribution to journal › Article › peer-review

Open Access

4 Scopus citations

Targeted Adenoviral Vectors I: Transductional Targeting

Dmitriev, I. P. & Kaliberov, S. A., Apr 6 2016, Adenoviral Vectors for Gene Therapy: Second Edition. Elsevier Inc., p. 231-257 27 p.

Research output: Chapter in Book/Report/Conference proceeding › Chapter › peer-review

4 Scopus citations

2015

Adenovirus vector expressing Stx1/Stx2-neutralizing agent protects piglets infected with Escherichia coli O157: H7 against fatal systemic intoxication

Sheoran, A. S., Dmitriev, I. P., Kashentseva, E. A., Cohen, O., Mukherjee, J., Debatis, M., Shearer, J., Tremblay, J. M., Beamer, G., Curiel, D. T., Shoemaker, C. B. & Tzipori, S., 2015, In: Infection and immunity. 83, 1, p. 286-291 6 p.

Research output: Contribution to journal › Article › peer-review

Open Access

20 Scopus citations

Erratum: Insulin-like growth factor-binding protein-7 (IGFBP7): A promising gene therapeutic for Hepatocellular Carcinoma (HCC) (Molecular Therapy (2013) 21 (758-766) DOI: 10.1038/mt.2012.282)

Chen, D., Siddiq, A., Emdad, L., Rajasekaran, D., Gredler, R., Shen, X. N., Santhekadur, P. K., Srivastava, J., Robertson, C. L., Dmitriev, I., Kashentseva, E. A., Curiel, D. T., Fisher, P. B. & Sarkar, D., Jul 1 2015, In: Molecular Therapy. 23, 7, p. 1278 1 p.

Research output: Contribution to journal › Comment/debate

Open Access

The N-Terminal Domain of SIRT1 Is a Positive Regulator of Endogenous SIRT1-Dependent Deacetylation and Transcriptional Outputs

Ghisays, F., Brace, C. S., Yackly, S. M., Kwon, H. J., Mills, K. F., Kashentseva, E., Dmitriev, I. P., Curiel, D. T., Imai, S. I. & Ellenberger, T., Mar 17 2015, In: Cell Reports. 10, 10, p. 1665-1673 9 p.

Research output: Contribution to journal › Article › peer-review

Open Access

61 Scopus citations

2014

Enhanced Prostate Cancer Gene Transfer and Therapy Using a Novel Serotype Chimera Cancer Terminator Virus (Ad.5/3-CTV)

Azab, B. M., Dash, R., Das, S. K., Bhutia, S. K., Sarkar, S., Shen, X. N., Quinn, B. A., Dent, P., Dmitriev, I. P., Wang, X. Y., Curiel, D. T., Pellecchia, M., Reed, J. C., Sarkar, D. & Fisher, P. B., Jan 1 2014, In: Journal of Cellular Physiology. 229, 1, p. 34-43 10 p.

Research output: Contribution to journal › Article › peer-review

Open Access

25 Scopus citations

Monitoring of biodistribution and persistence of conditionally replicative adenovirus in a murine model of ovarian cancer using capsid-incorporated mCherry and expression of human somatostatin receptor subtype 2 gene

Dmitriev, I. P., Kashentseva, E. A., Kim, K. H., Matthews, Q. L., Krieger, S. S., Parry, J. J., Nguyen, K. N., Akers, W. J., Achilefu, S., Rogers, B. E., Alvarez, R. D. & Curiel, D. T., Oct 1 2014, In: Molecular Imaging. 13, 8

Research output: Contribution to journal › Article › peer-review

6 Scopus citations

Prolonged prophylactic protection from botulism with a single adenovirus treatment promoting serum expression of a VHH-based antitoxin protein

Mukherjee, J., Dmitriev, I., Debatis, M., Tremblay, J. M., Beamer, G., Kashentseva, E. A., Curiel, D. T. & Shoemaker, C. B., Aug 29 2014, In: PloS one. 9, 8, e106422.

Research output: Contribution to journal › Article › peer-review

Open Access

30 Scopus citations

2013

A phase i clinical trial of Ad5/3-Δ24, a novel serotype-chimeric, infectivity-enhanced, conditionally-replicative adenovirus (CRAd), in patients with recurrent ovarian cancer

Kim, K. H., Dmitriev, I. P., Saddekni, S., Kashentseva, E. A., Harris, R. D., Aurigemma, R., Bae, S., Singh, K. P., Siegal, G. P., Curiel, D. T. & Alvarez, R. D., Sep 2013, In: Gynecologic oncology. 130, 3, p. 518-524 7 p.

Research output: Contribution to journal › Article › peer-review

Open Access

79 Scopus citations

Insulin-like growth factor-binding protein-7 (IGFBP7): A promising gene therapeutic for hepatocellular carcinoma (HCC)

Chen, D., Siddiq, A., Emdad, L., Rajasekaran, D., Gredler, R., Shen, X. N., Santhekadur, P. K., Srivastava, J., Robertson, C. L., Dmitriev, I., Kashentseva, E. A., Curiel, D. T., Fisher, P. B. & Sarkar, D., Apr 2013, In: Molecular Therapy. 21, 4, p. 758-766 9 p.

Research output: Contribution to journal › Article › peer-review

Open Access

45 Scopus citations

2012

A phase I clinical trial of Ad5.SSTR/TK.RGD, a novel infectivity-enhanced bicistronic adenovirus, in patients with recurrent gynecologic cancer

Kim, K. H., Dmitriev, I., O'Malley, J. P., Wang, M., Saddekni, S., You, Z., Preuss, M. A., Harris, R. D., Aurigemma, R., Siegal, G. P., Zinn, K. R., Curiel, D. T. & Alvarez, R. D., Jun 15 2012, In: Clinical Cancer Research. 18, 12, p. 3440-3451 12 p.

Research output: Contribution to journal › Article › peer-review

Open Access

51 Scopus citations

CryoEM Visualization of an Adenovirus Capsid-Incorporated HIV Antigen

Flatt, J. W., Fox, T. L., Makarova, N., Blackwell, J. L., Dmitriev, I. P., Kashentseva, E. A., Curiel, D. T. & Stewart, P. L., Nov 14 2012, In: PloS one. 7, 11, e49607.

Research output: Contribution to journal › Article › peer-review

Open Access

4 Scopus citations

Enhanced delivery of mda-7/IL-24 using a serotype chimeric adenovirus (Ad.5/3) in combination with the apogossypol derivative BI-97C1 (Sabutoclax) improves therapeutic efficacy in low CAR colorectal cancer cells

Azab, B., Dash, R., Das, S. K., Bhutia, S. K., Shen, X. N., Quinn, B. A., Sarkar, S., Wang, X. Y., Hedvat, M., Dmitriev, I. P., Curiel, D. T., Grant, S., Dent, P., Reed, J. C., Pellecchia, M., Sarkar, D. & Fisher, P. B., May 2012, In: Journal of Cellular Physiology. 227, 5, p. 2145-2153 9 p.

Research output: Contribution to journal › Article › peer-review

Open Access

47 Scopus citations

2011

Apogossypol derivative BI-97C1 (Sabutoclax) targeting Mcl-1 sensitizes prostate cancer cells to mda-7/IL-24-mediated toxicity

Dash, R., Azab, B., Quinn, B. A., Shen, X., Wang, X. Y., Das, S. K., Rahmani, M., Wei, J., Hedvat, M., Dent, P., Dmitriev, I. P., Curiel, D. T., Grant, S., Wu, B., Stebbins, J. L., Pellecchia, M., Reed, J. C., Sarkar, D. & Fisher, P. B., May 24 2011, In: Proceedings of the National Academy of Sciences of the United States of America. 108, 21, p. 8785-8790 6 p.

Research output: Contribution to journal › Article › peer-review

Open Access

114 Scopus citations

A serotype 5/3 adenovirus expressing MDA-7/IL-24 infects renal carcinoma cells and promotes toxicity of agents that increase ros and ceramide levels

Park, M. A., Hamed, H. A., Mitchell, C., Cruickshanks, N., Dash, R., Allegood, J., Dmitriev, I. P., Tye, G., Ogretmen, B., Spiegel, S., Yacoub, A., Grant, S., Curiel, D. T., Fisher, P. B. & Dent, P., Mar 2011, In: Molecular pharmacology. 79, 3, p. 368-380 13 p.

Research output: Contribution to journal › Article › peer-review

24 Scopus citations

Developing an effective gene therapy for prostate cancer: New technologies with potential to translate from the laboratory into the clinic.

Dash, R., Azab, B., Shen, X. N., Sokhi, U. K., Sarkar, S., Su, Z. Z., Wang, X. Y., Claudio, P. P., Dent, P., Dmitriev, I. P., Curiel, D. T., Grant, S., Sarkar, D. & Fisher, P. B., Jan 2011, In: Discovery medicine. 11, 56, p. 46-56 11 p.

Research output: Contribution to journal › Review article › peer-review

33 Scopus citations

Targeting Mcl-1 for the therapy of cancer

Quinn, B. A., Dash, R., Azab, B., Sarkar, S., Das, S. K., Kumar, S., Oyesanya, R. A., Dasgupta, S., Dent, P., Grant, S., Rahmani, M., Curiel, D. T., Dmitriev, I., Hedvat, M., Wei, J., Wu, B., Stebbins, J. L., Reed, J. C., Pellecchia, M. & Sarkar, D. & 1 others, Fisher, P. B., Oct 2011, In: Expert Opinion on Investigational Drugs. 20, 10, p. 1397-1411 15 p.

Research output: Contribution to journal › Review article › peer-review

Open Access

170 Scopus citations

2010

Cisplatin enhances protein kinase R-like endoplasmic reticulum kinase- and CD95-dependent melanoma differentiation-associated gene-7/interleukin-24-induced killing in ovarian carcinoma cells

Yacoub, A., Liu, R., Park, M. A., Hamed, H. A., Dash, R., Schramm, D. N., Sarkar, D., Dmitriev, I., Bell, J. K., Grant, S., Farrell, N. P., Curiel, D. T., Fisher, P. B. & Dent, P., Feb 2010, In: Molecular pharmacology. 77, 2, p. 298-310 13 p.

Research output: Contribution to journal › Article › peer-review

Open Access

34 Scopus citations

Enhanced delivery of mda-7/IL-24 using a serotype chimeric adenovirus (Ad.5/3) improves therapeutic efficacy in low CAR prostate cancer cells

Dash, R., Dmitriev, I., Su, Z. Z., Bhutia, S. K., Azab, B., Vozhilla, N., Yacoub, A., Dent, P., Curiel, D. T., Sarkar, D. & Fisher, P. B., Jul 2010, In: Cancer gene therapy. 17, 7, p. 447-456 10 p.

Research output: Contribution to journal › Article › peer-review

47 Scopus citations

Enhancing mda-7/IL-24 therapy in renal carcinoma cells by inhibiting multiple protective signaling pathways using sorafenib and by Ad.5/3 gene delivery

Eulitt, P. J., Park, M. A., Hamed, H. A., Cruikshanks, N., Yang, C., Dmitriev, I. P., Yacoub, A., Curiel, D. T., Fisher, P. B. & Dent, P., Dec 15 2010, In: Cancer Biology and Therapy. 10, 12, p. 1290-1305 16 p.

Research output: Contribution to journal › Article › peer-review

Open Access

27 Scopus citations

Igor Dmitriev

Research output

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