Guy Genin

2021

Torsional and translational vibrations of a eukaryotic nucleus, and the prospect of vibrational mechanotransduction and therapy

Liu, S., Yang, H., Wang, M., Tian, J., Hong, Y., Li, Y., Genin, G. M., Lu, T. J. & Xu, F., Oct 2021, In: Journal of the Mechanics and Physics of Solids. 155, 104572.

Research output: Contribution to journal › Article › peer-review

4 Scopus citations

Toughening mechanisms for the attachment of architectured materials: The mechanics of the tendon enthesis

Golman, M., Abraham, A. C., Kurtaliaj, I., Marshall, B. P., Hu, Y. J., Schwartz, A. G., Edward Guo, X., Birman, V., Thurner, P. J., Genin, G. M. & Thomopoulos, S., Nov 2021, In: Science Advances. 7, 48, eabi5584.

Research output: Contribution to journal › Article › peer-review

Open Access

29 Scopus citations

2020

Characterizing poroelasticity of biological tissues by spherical indentation: An improved theory for large relaxation

Wang, M., Liu, S., Xu, Z., Qu, K., Li, M., Chen, X., Xue, Q., Genin, G. M., Lu, T. J. & Xu, F., May 2020, In: Journal of the Mechanics and Physics of Solids. 138, 103920.

Research output: Contribution to journal › Article › peer-review

Open Access

23 Scopus citations

Correction of bias in the estimation of cell volume fraction from histology sections

Liu, Y., Schwartz, A. G., Hong, Y., Peng, X., Xu, F., Thomopoulos, S. & Genin, G. M., May 7 2020, In: Journal of Biomechanics. 104, 109705.

Research output: Contribution to journal › Article › peer-review

Open Access

4 Scopus citations

Direct estimation of surface strain fields from a stereo vision system

Boyle, J. J., Pless, R. B., Thomopoulos, S. & Genin, G. M., Jul 2020, In: Journal of Biomechanical Engineering. 142, 7, 074503-1.

Research output: Contribution to journal › Article › peer-review

Open Access

1 Scopus citations

Fluorescence Correlation Spectroscopy and Photon Counting Histograms in Finite, Bounded Domains

Jiang, Y., Xu, B., Melnykov, A., Genin, G. M. & Elson, E. L., Jul 21 2020, In: Biophysical Journal. 119, 2, p. 265-273 9 p.

Research output: Contribution to journal › Article › peer-review

Open Access

5 Scopus citations

Mechanics tuning of liquid inclusions via bio-coating

Chen, X., Li, M., Liu, S., He, W., Ti, F., Dong, Y., Genin, G. M., Xu, F. & Lu, T. J., Nov 2020, In: Extreme Mechanics Letters. 41, 101049.

Research output: Contribution to journal › Article › peer-review

10 Scopus citations

Modeling the mechanics, kinetics, and network evolution of photopolymerized hydrogels

Zhu, H., Yang, X., Genin, G. M., Lu, T. J., Xu, F. & Lin, M., Sep 2020, In: Journal of the Mechanics and Physics of Solids. 142, 104041.

Research output: Contribution to journal › Article › peer-review

13 Scopus citations

Nanoscale integrin cluster dynamics controls cellular mechanosensing via FAKY397 phosphorylation

Cheng, B., Wan, W., Huang, G., Li, Y., Genin, G. M., Mofrad, M. R. K., Lu, T. J., Xu, F. & Lin, M., 2020, In: Science Advances. 6, 10, eaax1909.

Research output: Contribution to journal › Article › peer-review

Open Access

93 Scopus citations

Standing surface acoustic waves, and the mechanics of acoustic tweezer manipulation of eukaryotic cells

Peng, X., He, W., Xin, F., Genin, G. M. & Lu, T. J., Dec 2020, In: Journal of the Mechanics and Physics of Solids. 145, 104134.

Research output: Contribution to journal › Article › peer-review

15 Scopus citations

The acoustic radiation force of a focused ultrasound beam on a suspended eukaryotic cell

Peng, X., He, W., Xin, F., Genin, G. M. & Lu, T. J., Dec 2020, In: Ultrasonics. 108, 106205.

Research output: Contribution to journal › Article › peer-review

Open Access

23 Scopus citations

The Balance between Actomyosin Contractility and Microtubule Polymerization Regulates Hierarchical Protrusions That Govern Efficient Fibroblast-Collagen Interactions

Shakiba, D., Alisafaei, F., Savadipour, A., Rowe, R. A., Liu, Z., Pryse, K. M., Shenoy, V. B., Elson, E. L. & Genin, G. M., Jul 28 2020, In: ACS nano. 14, 7, p. 7868-7879 12 p.

Research output: Contribution to journal › Article › peer-review

40 Scopus citations

2019

Adhesive-based tendon-to-bone repair: Failure modelling and materials selection

Avgoulas, E. I., Sutcliffe, M. P. F., Linderman, S. W., Birman, V., Thomopoulos, S. & Genin, G. M., Apr 3 2019, In: Journal of the Royal Society Interface. 16, 153, 20180838.

Research output: Contribution to journal › Article › peer-review

Open Access

9 Scopus citations

A preliminary study of the local biomechanical environment of liver tumors in vivo

Ma, S., Zhu, M., Xia, X., Guo, L., Genin, G. M., Sacks, M. S., Gao, M., Mutic, S., Hu, Y., Hu, C. H. & Feng, Y., Apr 2019, In: Medical physics. 46, 4, p. 1728-1739 12 p.

Research output: Contribution to journal › Article › peer-review

2 Scopus citations

Atomic force microscopy of phase separation on ruptured, giant unilamellar vesicles, and a mechanical pathway for the co-existence of lipid gel phases

Jiang, Y., Pryse, K. M., Singamaneni, S., Genin, G. M. & Elson, E. L., Jul 1 2019, In: Journal of Biomechanical Engineering. 141, 7, 071003.

Research output: Contribution to journal › Article › peer-review

1 Scopus citations

Cryoprotectant enables structural control of porous scaffolds for exploration of cellular mechano-responsiveness in 3D

Jiang, S., Lyu, C., Zhao, P., Li, W., Kong, W., Huang, C., Genin, G. M. & Du, Y., Dec 1 2019, In: Nature communications. 10, 1, 3491.

Research output: Contribution to journal › Article › peer-review

Open Access

145 Scopus citations

Electrostatic switching of nuclear basket conformations provides a potential mechanism for nuclear mechanotransduction

Liu, S., Yang, H., Lu, T. J., Genin, G. M. & Xu, F., Dec 2019, In: Journal of the Mechanics and Physics of Solids. 133, 103705.

Research output: Contribution to journal › Article › peer-review

Open Access

7 Scopus citations

Programmable and robust static topological solitons in mechanical metamaterials

Zhang, Y., Li, B., Zheng, Q. S., Genin, G. M. & Chen, C. Q., Dec 1 2019, In: Nature communications. 10, 1, 5605.

Research output: Contribution to journal › Article › peer-review

Open Access

87 Scopus citations

Regularization-Free Strain Mapping in Three Dimensions, with Application to Cardiac Ultrasound

Boyle, J. J., Soepriatna, A., Damen, F., Rowe, R. A., Pless, R. B., Kovacs, A., Goergen, C. J., Thomopoulos, S. & Genin, G. M., Jan 1 2019, In: Journal of Biomechanical Engineering. 141, 1, 0110101.

Research output: Contribution to journal › Article › peer-review

Open Access

18 Scopus citations

Regulation of cell behavior by hydrostatic pressure

Liu, S., Tao, R., Wang, M., Tian, J., Genin, G. M., Lu, T. J. & Xu, F., Jul 2019, In: Applied Mechanics Reviews. 71, 4, 040803.

Research output: Contribution to journal › Article › peer-review

37 Scopus citations

The multiscale structural and mechanical effects of mouse supraspinatus muscle unloading on the mature enthesis

Deymier, A. C., Schwartz, A. G., Cai, Z., Daulton, T. L., Pasteris, J. D., Genin, G. M. & Thomopoulos, S., Jan 1 2019, In: Acta Biomaterialia. 83, p. 302-313 12 p.

Research output: Contribution to journal › Article › peer-review

Open Access

55 Scopus citations

Translation of a coated rigid spherical inclusion in an elastic matrix: Exact solution, and implications for mechanobiology

Chen, X., Li, M., Liu, S., Liu, F., Genin, G. M., Xu, F. & Lu, T. J., May 1 2019, In: Journal of Applied Mechanics, Transactions ASME. 86, 5, 051002.

Research output: Contribution to journal › Article › peer-review

Open Access

6 Scopus citations

Volumetric response of an ellipsoidal liquid inclusion: implications for cell mechanobiology

Chen, X., He, W., Liu, S., Li, M., Genin, G. M., Xu, F. & Lu, T. J., Apr 3 2019, In: Acta Mechanica Sinica/Lixue Xuebao. 35, 2, p. 338-342 5 p.

Research output: Contribution to journal › Article › peer-review

9 Scopus citations

2018

Energy dissipation in mammalian collagen fibrils: Cyclic strain-induced damping, toughening, and strengthening

Liu, J., Das, D., Yang, F., Schwartz, A. G., Genin, G. M., Thomopoulos, S. & Chasiotis, I., Oct 15 2018, In: Acta Biomaterialia. 80, p. 217-227 11 p.

Research output: Contribution to journal › Article › peer-review

Open Access

41 Scopus citations

Energy dissipation in quasi-linear viscoelastic tissues, cells, and extracellular matrix

Babaei, B., Velasquez-Mao, A. J., Pryse, K. M., McConnaughey, W. B., Elson, E. L. & Genin, G. M., Aug 2018, In: Journal of the Mechanical Behavior of Biomedical Materials. 84, p. 198-207 10 p.

Research output: Contribution to journal › Article › peer-review

Open Access

14 Scopus citations

Enhanced tendon-to-bone repair through adhesive films

Linderman, S. W., Golman, M., Gardner, T. R., Birman, V., Levine, W. N., Genin, G. M. & Thomopoulos, S., Apr 1 2018, In: Acta Biomaterialia. 70, p. 165-176 12 p.

Research output: Contribution to journal › Article › peer-review

Open Access

27 Scopus citations

Non-contact tensile viscoelastic characterization of microscale biological materials

Li, Y., Hong, Y., Xu, G. K., Liu, S., Shi, Q., Tang, D., Yang, H., Genin, G. M., Lu, T. J. & Xu, F., Jun 1 2018, In: Acta Mechanica Sinica/Lixue Xuebao. 34, 3, p. 589-599 11 p.

Research output: Contribution to journal › Article › peer-review

13 Scopus citations

Reduced graphene oxide functionalized nanofibrous silk fibroin matrices for engineering excitable tissues

Zhao, G., Qing, H., Huang, G., Genin, G. M., Lu, T. J., Luo, Z., Xu, F. & Zhang, X., Oct 1 2018, In: NPG Asia Materials. 10, 10, p. 982-994 13 p.

Research output: Contribution to journal › Article › peer-review

Open Access

107 Scopus citations

The elastic fields of a compressible liquid inclusion

Chen, X., Li, M., Yang, M., Liu, S., Genin, G. M., Xu, F. & Lu, T. J., Jul 2018, In: Extreme Mechanics Letters. 22, p. 122-130 9 p.

Research output: Contribution to journal › Article › peer-review

47 Scopus citations

The relationship between thiol-acrylate photopolymerization kinetics and hydrogel mechanics: An improved model incorporating photobleaching and thiol-Michael addition

Zhu, H., Yang, X., Genin, G. M., Lu, T. J., Xu, F. & Lin, M., Dec 2018, In: Journal of the Mechanical Behavior of Biomedical Materials. 88, p. 160-169 10 p.

Research output: Contribution to journal › Article › peer-review

Open Access

16 Scopus citations

2017

Arabidopsis Leaf Trichomes as Acoustic Antennae

Liu, S., Jiao, J., Lu, T. J., Xu, F., Pickard, B. G. & Genin, G. M., Nov 7 2017, In: Biophysical Journal. 113, 9, p. 2068-2076 9 p.

Research output: Contribution to journal › Article › peer-review

Open Access

41 Scopus citations

Collective Wetting of a Natural Fibrous System and Its Application in Pump-Free Droplet Transfer

Han, Y. L., Li, M., Yang, Q., Huang, G., Liu, H., Qin, Y., Genin, G. M., Li, F., Lu, T. J. & Xu, F., Jun 13 2017, In: Advanced Functional Materials. 27, 22, 1606607.

Research output: Contribution to journal › Article › peer-review

23 Scopus citations

Discrete quasi-linear viscoelastic damping analysis of connective tissues, and the biomechanics of stretching

Babaei, B., Velasquez-Mao, A. J., Thomopoulos, S., Elson, E. L., Abramowitch, S. D. & Genin, G. M., May 1 2017, In: Journal of the Mechanical Behavior of Biomedical Materials. 69, p. 193-202 10 p.

Research output: Contribution to journal › Article › peer-review

Open Access

26 Scopus citations

Fibroblasts Slow Conduction Velocity in a Reconstituted Tissue Model of Fibrotic Cardiomyopathy

Spencer, T. M., Blumenstein, R. F., Pryse, K. M., Lee, S. L., Glaubke, D. A., Carlson, B. E., Elson, E. L. & Genin, G. M., Nov 13 2017, In: ACS Biomaterials Science and Engineering. 3, 11, p. 3022-3028 7 p.

Research output: Contribution to journal › Article › peer-review

Open Access

16 Scopus citations

Investigation of Nanoscopic Phase Separations in Lipid Membranes Using Inverse FCS

Jiang, Y., Pryse, K. M., Melnykov, A., Genin, G. M. & Elson, E. L., Jun 6 2017, In: Biophysical Journal. 112, 11, p. 2367-2376 10 p.

Research output: Contribution to journal › Article › peer-review

Open Access

12 Scopus citations

Melting Away Pain: Decay of Thermal Nociceptor Transduction during Heat-Induced Irreversible Desensitization of Ion Channels

Lin, M., Liu, S. B., Genin, G. M., Zhu, Y., Shi, M., Ji, C., Li, A., Lu, T. J. & Xu, F., Nov 13 2017, In: ACS Biomaterials Science and Engineering. 3, 11, p. 3029-3035 7 p.

Research output: Contribution to journal › Article › peer-review

4 Scopus citations

Micro-mechanical properties of the tendon-to-bone attachment

Deymier, A. C., An, Y., Boyle, J. J., Schwartz, A. G., Birman, V., Genin, G. M., Thomopoulos, S. & Barber, A. H., Jul 1 2017, In: Acta Biomaterialia. 56, p. 25-35 11 p.

Research output: Contribution to journal › Article › peer-review

Open Access

67 Scopus citations

Protein-free formation of bone-like apatite: New insights into the key role of carbonation

Deymier, A. C., Nair, A. K., Depalle, B., Qin, Z., Arcot, K., Drouet, C., Yoder, C. H., Buehler, M. J., Thomopoulos, S., Genin, G. M. & Pasteris, J. D., May 1 2017, In: Biomaterials. 127, p. 75-88 14 p.

Research output: Contribution to journal › Article › peer-review

Open Access

78 Scopus citations

The Arabidopsis trichome is an active mechanosensory switch

Zhou, L. H., Liu, S. B., Wang, P. F., Lu, T. J., Xu, F., Genin, G. M. & Pickard, B. G., May 1 2017, In: Plant, Cell & Environment. 40, 5, p. 611-621 11 p.

Research output: Contribution to journal › Article › peer-review

Open Access

61 Scopus citations

Toughening of fibrous scaffolds by mobile mineral deposits

Lipner, J., Boyle, J. J., Xia, Y., Birman, V., Genin, G. M. & Thomopoulos, S., Aug 2017, In: Acta Biomaterialia. 58, p. 492-501 10 p.

Research output: Contribution to journal › Article › peer-review

Open Access

14 Scopus citations

2016

An approach to quantifying 3D responses of cells to extreme strain

Li, Y., Huang, G., Li, M., Wang, L., Elson, E. L., Jian Lu, T., Genin, G. M. & Xu, F., Feb 18 2016, In: Scientific reports. 6, 19550.

Research output: Contribution to journal › Article › peer-review

Open Access

40 Scopus citations

An Integrated Stochastic Model of Matrix-Stiffness-Dependent Filopodial Dynamics

Cheng, B., Lin, M., Li, Y., Huang, G., Yang, H., Genin, G. M., Deshpande, V. S., Lu, T. J. & Xu, F., Nov 1 2016, In: Biophysical Journal. 111, 9, p. 2051-2061 11 p.

Research output: Contribution to journal › Article › peer-review

Open Access

30 Scopus citations

Efficient and optimized identification of generalized Maxwell viscoelastic relaxation spectra

Babaei, B., Davarian, A., Pryse, K. M., Elson, E. L. & Genin, G. M., Mar 2016, In: Journal of the Mechanical Behavior of Biomedical Materials. 55, p. 32-41 10 p.

Research output: Contribution to journal › Article › peer-review

Open Access

71 Scopus citations

Integrated multiscale biomaterials experiment and modelling: A perspective

Buehler, M. J. & Genin, G. M., Feb 6 2016, In: Interface Focus. 6, 1, p. 1-5 5 p., 20150098.

Research output: Contribution to journal › Article › peer-review

Open Access

6 Scopus citations

Magnetically actuated cell-laden microscale hydrogels for probing strain-induced cell responses in three dimensions

Li, Y., Huang, G., Gao, B., Li, M., Genin, G. M., Lu, T. J. & Xu, F., 2016, In: NPG Asia Materials. 8, 1, e238.

Research output: Contribution to journal › Article › peer-review

Open Access

59 Scopus citations

Multi-scale Modeling in Clinical Oncology: Opportunities and Barriers to Success

Yankeelov, T. E., An, G., Saut, O., Luebeck, E. G., Popel, A. S., Ribba, B., Vicini, P., Zhou, X., Weis, J. A., Ye, K. & Genin, G. M., Sep 1 2016, In: Annals of biomedical engineering. 44, 9, p. 2626-2641 16 p.

Research output: Contribution to journal › Article › peer-review

Open Access

62 Scopus citations

On the accuracy and fitting of transversely isotropic material models

Feng, Y., Okamoto, R. J., Genin, G. M. & Bayly, P. V., Aug 1 2016, In: Journal of the Mechanical Behavior of Biomedical Materials. 61, p. 554-566 13 p.

Research output: Contribution to journal › Article › peer-review

Open Access

39 Scopus citations

Remodeling by fibroblasts alters the rate-dependent mechanical properties of collagen

Babaei, B., Davarian, A., Lee, S. L., Pryse, K. M., McConnaughey, W. B., Elson, E. L. & Genin, G. M., Jun 1 2016, In: Acta Biomaterialia. 37, p. 28-37 10 p.

Research output: Contribution to journal › Article › peer-review

Open Access

34 Scopus citations

The concentration of stress at the rotator cuff tendon-to-bone attachment site is conserved across species

Saadat, F., Deymier, A. C., Birman, V., Thomopoulos, S. & Genin, G. M., Sep 1 2016, In: Journal of the Mechanical Behavior of Biomedical Materials. 62, p. 24-32 9 p.

Research output: Contribution to journal › Article › peer-review

Open Access

27 Scopus citations

Tunability of collagen matrix mechanical properties via multiple modes of mineralization

Smith, L. J., Deymier, A. C., Boyle, J. J., Li, Z., Linderman, S. W., Pasteris, J. D., Xia, Y., Genin, G. M. & Thomopoulos, S., Feb 6 2016, In: Interface Focus. 6, 1, 20150070.

Research output: Contribution to journal › Article › peer-review

Open Access

28 Scopus citations

Guy Genin

Research output

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