Gregory Lanza

2003

Molecular imaging of angiogenesis in nascent Vx-2 rabbit tumors using a novel α_vβ₃-targeted nanoparticle and 1.5 Tesla magnetic resonance imaging

Winter, P. M., Caruthers, S. D., Kassner, A., Harris, T. D., Chinen, L. K., Allen, J. S., Lacy, E. K., Zhang, H., Robertson, J. D., Wickline, S. A. & Lanza, G. M., Sep 15 2003, In: Cancer research. 63, 18, p. 5838-5843 6 p.

Research output: Contribution to journal › Article › peer-review

393 Scopus citations

Targeted ultrasonic contrast agents for molecular imaging and therapy.

Lanza, G. M. & Wickline, S. A., Dec 2003, In: Current problems in cardiology. 28, 12, p. 625-653 29 p.

Research output: Contribution to journal › Article › peer-review

105 Scopus citations

2004

Clinical Utility of Rapid Prescreening Magnetic Resonance Angiography of Peripheral Vascular Disease Prior to Cardiac Catheterization

Rogers, J. H., Caruthers, S. D., Williams, T., Lin, S. J. R., Meyers, D., Lanza, G. M., Kovacs, S., Lasala, J. M. & Wickline, S. A., 2004, In: Journal of Cardiovascular Magnetic Resonance. 6, 1, p. 25-31 7 p.

Research output: Contribution to journal › Article › peer-review

3 Scopus citations

Magnetic resonance molecular imaging with nanoparticles

Lanza, G. M., Winter, P. M., Caruthers, S. D., Morawski, A. M., Schmieder, A. H., Crowder, K. C. & Wickline, S. A., 2004, In: Journal of Nuclear Cardiology. 11, 6, p. 733-743 11 p.

Research output: Contribution to journal › Article › peer-review

135 Scopus citations

Quantification of stenotic mitral valve area with magnetic resonance imaging and comparison with Doppler ultrasound

Lin, S. J., Brown, P. A., Watkins, M. P., Williams, T. A., Lehr, K. A., Liu, W., Lanza, G. M., Wickline, S. A. & Caruthers, S. D., Jul 7 2004, In: Journal of the American College of Cardiology. 44, 1, p. 133-137 5 p.

Research output: Contribution to journal › Article › peer-review

Open Access

61 Scopus citations

Quantitative "magnetic resonance immunohistochemistry" with ligand-targeted ¹⁹F nanoparticles

Morawski, A. M., Winter, P. M., Yu, X., Fuhrhop, R. W., Scott, M. J., Hockett, F., Robertson, J. D., Gaffney, P. J., Lanza, G. M. & Wickline, S. A., Dec 2004, In: Magnetic resonance in medicine. 52, 6, p. 1255-1262 8 p.

Research output: Contribution to journal › Article › peer-review

Open Access

187 Scopus citations

Targeted Nanoparticles for Quantitative Imaging of Sparse Molecular Epitopes with MRI

Morawski, A. M., Winter, P. M., Crowder, K. C., Caruthers, S. D., Fuhrhop, R. W., Scott, M. J., Robertson, J. D., Abendschein, D. R., Lanza, G. M. & Wickline, S. A., Mar 2004, In: Magnetic resonance in medicine. 51, 3, p. 480-486 7 p.

Research output: Contribution to journal › Article › peer-review

Open Access

243 Scopus citations

Ultrasonic delineation of aortic microstructure: The relative contribution of elastin and collagen to aortic elasticity

Marsh, J. N., Takiuchi, S., Lin, S. J., Lanza, G. M. & Wickline, S. A., May 2004, In: Journal of the Acoustical Society of America. 115, 5 I, p. 2032-2040 9 p.

Research output: Contribution to journal › Article › peer-review

13 Scopus citations

2005

Acoustic characterization in whole blood and plasma of site-targeted nanoparticle ultrasound contrast agent for molecular imaging

Hughes, M. S., Marsh, J. N., Hall, C. S., Fuhrhop, R. W., Lacy, E. K., Lanza, G. M. & Wickline, S. A., Feb 2005, In: Journal of the Acoustical Society of America. 117, 2, p. 964-972 9 p.

Research output: Contribution to journal › Article › peer-review

42 Scopus citations

Characterization and biodistribution of a novel MRI molecular imaging agent by neutron activation analysis

Robertson, J. D., Crane, S. B., Wickline, S. A. & Lanza, G. M., 2005, In: Journal of Radioanalytical and Nuclear Chemistry. 263, 2, p. 511-514 4 p.

Research output: Contribution to journal › Article › peer-review

2 Scopus citations

Characterization of digital waveforms using thermodynamic analogs: Applications to detection of materials defects

Hughes, M. S., Marsh, J. N., Hall, C. S., Savéry, D., Lanza, G. M. & Wickline, S. A., Sep 2005, In: IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control. 52, 9, p. 1555-1564 10 p.

Research output: Contribution to journal › Article › peer-review

21 Scopus citations

Improved paramagnetic chelate for molecular imaging with MRI

Winter, P., Athey, P., Kiefer, G., Gulyas, G., Frank, K., Fuhrhop, R., Robertson, D., Wickline, S. & Lanza, G., May 2005, In: Journal of Magnetism and Magnetic Materials. 293, 1, p. 540-545 6 p.

Research output: Contribution to journal › Article › peer-review

42 Scopus citations

Molecular imaging of human thrombus with computed tomography

Winter, P. M., Shukla, H. P., Caruthers, S. D., Scott, M. J., Fuhrhop, R. W., Robertson, J. D., Gaffney, P. J., Wickline, S. A. & Lanza, G. M., May 2005, In: Academic radiology. 12, 5 SUPPL. 1, p. S9-S13

Research output: Contribution to journal › Article › peer-review

52 Scopus citations

Molecular MR imaging of melanoma angiogenesis with α _νβ₃-targeted paramagnetic nanoparticles

Schmieder, A. H., Winter, P. M., Caruthers, S. D., Harris, T. D., Williams, T. A., Allen, J. S., Lacy, E. K., Zhang, H., Scott, M. J., Hu, G., Robertson, J. D., Wickline, S. A. & Lanza, G. M., Mar 2005, In: Magnetic resonance in medicine. 53, 3, p. 621-627 7 p.

Research output: Contribution to journal › Article › peer-review

Open Access

238 Scopus citations

Sonic activation of molecularly-targeted nanoparticles accelerates transmembrane lipid delivery to cancer cells through contact-mediated mechanisms: Implications for enhanced local drug delivery

Crowder, K. C., Hughes, M. S., Marsh, J. N., Barbieri, A. M., Fuhrhop, R. W., Lanza, G. M. & Wickline, S. A., Dec 2005, In: Ultrasound in Medicine and Biology. 31, 12, p. 1693-1700 8 p.

Research output: Contribution to journal › Article › peer-review

65 Scopus citations

WE‐C‐T‐6E‐04: Nanotechnology for Molecular Imaging

Lanza, G., Jun 2005, In: Medical physics. 32, 6, 1 p.

Research output: Contribution to journal › Article › peer-review

1 Scopus citations

2006

Acoustic activation of targeted liquid perfluorocarbon nanoparticles does not compromise endothelial integrity

Soman, N. R., Marsh, J. N., Hughes, M. S., Lanza, G. M. & Wickline, S. A., Jun 2006, In: IEEE Transactions on Nanobioscience. 5, 2, p. 69-75 7 p., 1637446.

Research output: Contribution to journal › Article › peer-review

15 Scopus citations

Characterization of digital waveforms using thermodynamic analogs: Detection of contrast-targeted tissue in vivo

Hughes, M. S., Marsh, J. N., Zhang, H., Woodson, A. K., Allen, J. S., Lacy, E. K., Carradine, C., Lanza, G. M. & Wickline, S. A., Sep 2006, In: IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control. 53, 9, p. 1609-1616 8 p., 1678189.

Research output: Contribution to journal › Article › peer-review

46 Scopus citations

Endothelial α_νβ₃ integrin-targeted fumagillin nanoparticles inhibit angiogenesis in atherosclerosis

Winter, P. M., Neubauer, A. M., Caruthers, S. D., Harris, T. D., Robertson, J. D., Williams, T. A., Schmieder, A. H., Hu, G., Allen, J. S., Lacy, E. K., Zhang, H., Wickline, S. A. & Lanza, G. M., Sep 2006, In: Arteriosclerosis, thrombosis, and vascular biology. 26, 9, p. 2103-2109 7 p.

Research output: Contribution to journal › Article › peer-review

351 Scopus citations

In vitro demonstration using 19F magnetic resonance to augment molecular imaging with paramagnetic perfluorocarbon nanoparticles at 1.5 tesla

Caruthers, S. D., Neubauer, A. M., Hockett, F. D., Lamerichs, R., Winter, P. M., Scott, M. J., Gaffney, P. J., Wickline, S. A. & Lanza, G. M., Mar 2006, In: Investigative Radiology. 41, 3, p. 305-312 8 p.

Research output: Contribution to journal › Article › peer-review

95 Scopus citations

MR three-dimensional molecular imaging of intramural biomarkers with targeted nanoparticles.

Cyrus, T., Abendschein, D. R., Caruthers, S. D., Harris, T. D., Glattauer, V., Werkmeister, J. A., Ramshaw, J. A. M., Wickline, S. A. & Lanza, G. M., 2006, In: Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance. 8, 3, p. 535-541 7 p.

Research output: Contribution to journal › Article › peer-review

36 Scopus citations

Targeted PARACEST nanoparticle contrast agent for the detection of fibrin

Winter, P. M., Cai, K., Chen, J., Adair, C. R., Kiefer, G. E., Athey, P. S., Gaffney, P. J., Buff, C. E., Robertson, J. D., Caruthers, S. D., Wickline, S. A. & Lanza, G. M., Dec 2006, In: Magnetic resonance in medicine. 56, 6, p. 1384-1388 5 p.

Research output: Contribution to journal › Article › peer-review

Open Access

84 Scopus citations

2007

¹⁹F magnetic resonance imaging for stem/progenitor cell tracking with multiple unique perfluorocarbon nanobeacons

Partlow, K. C., Chen, J., Brant, J. A., Neubauer, A. M., Meyerrose, T. E., Creer, M. H., Nolta, J. A., Caruthers, S. D., Lanza, G. M. & Wickline, S. A., Jun 2007, In: FASEB Journal. 21, 8, p. 1647-1654 8 p.

Research output: Contribution to journal › Article › peer-review

286 Scopus citations

Fibrin-targeted perfluorocarbon nanoparticles for targeted thrombolysis

Marsh, J. N., Senpan, A., Hu, G., Scott, M. J., Gaffney, P. J., Wickline, S. A. & Lanza, G. M., Aug 2007, In: Nanomedicine. 2, 4, p. 533-543 11 p.

Research output: Contribution to journal › Article › peer-review

105 Scopus citations

Fluorine cardiovascular magnetic resonance angiography in vivo at 1.5 T with perfluorocarbon nanoparticle contrast agents

Neubauer, A. M., Caruthers, S. D., Hockett, F. D., Cyrus, T., Robertson, J. D., Allen, J. S., Williams, T. D., Fuhrhop, R. W., Lanza, G. M. & Wickline, S. A., May 2007, In: Journal of Cardiovascular Magnetic Resonance. 9, 3, p. 565-573 9 p.

Research output: Contribution to journal › Article › peer-review

40 Scopus citations

Imaging of Vx-2 rabbit tumors with α_vβ₃- integrin-targeted ¹¹¹In nanoparticles

Hu, G., Lijowski, M., Zhang, H., Partlow, K. C., Caruthers, S. D., Kiefer, G., Gulyas, G., Athey, P., Scott, M. J., Wickline, S. A. & Lanza, G. M., May 1 2007, In: International Journal of Cancer. 120, 9, p. 1951-1957 7 p.

Research output: Contribution to journal › Article › peer-review

117 Scopus citations

Molecular imaging by cardiovascular MR

Cyrus, T., Lanza, G. M. & Wickline, S. A., Nov 2007, In: Journal of Cardiovascular Magnetic Resonance. 9, 6, p. 827-843 17 p.

Research output: Contribution to journal › Article › peer-review

22 Scopus citations

Molecular Imaging With Targeted Perfluorocarbon Nanoparticles: Quantification of the Concentration Dependence of Contrast Enhancement for Binding to Sparse Cellular Epitopes

Marsh, J. N., Partlow, K. C., Abendschein, D. R., Scott, M. J., Lanza, G. M. & Wickline, S. A., Jun 2007, In: Ultrasound in Medicine and Biology. 33, 6, p. 950-958 9 p.

Research output: Contribution to journal › Article › peer-review

54 Scopus citations

Properties of an entropy-based signal receiver with an application to ultrasonic molecular imaging

Hughes, M. S., McCarthy, J. E., Marsh, J. N., Arbeit, J. M., Neumann, R. G., Fuhrhop, R. W., Wallace, K. D., Znidersic, D. R., Maurizi, B. N., Baldwin, S. L., Lanza, G. M. & Wickline, S. A., 2007, In: Journal of the Acoustical Society of America. 121, 6, p. 3542-3557 16 p.

Research output: Contribution to journal › Article › peer-review

48 Scopus citations

Sensitive ultrasonic delineation of steroid treatment in living dystrophic mice with energy-based and entropy-based radio frequency signal processing

Wallace, K. D., Marsh, J. N., Baldwin, S. L., Connolly, A. M., Keeling, R., Lanza, G. M., Wickline, S. A. & Hughes, M. S., Nov 2007, In: IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control. 54, 11, p. 2291-2299 9 p.

Research output: Contribution to journal › Article › peer-review

23 Scopus citations

Sensitive Ultrasonic Detection of Dystrophic Skeletal Muscle in Patients with Duchenne Muscular Dystrophy Using an Entropy-Based Signal Receiver

Hughes, M. S., Marsh, J. N., Wallace, K. D., Donahue, T. A., Connolly, A. M., Lanza, G. M. & Wickline, S. A., Aug 2007, In: Ultrasound in Medicine and Biology. 33, 8, p. 1236-1243 8 p.

Research output: Contribution to journal › Article › peer-review

29 Scopus citations

Spectral properties of a bifunctional PARACEST europium chelate: An intermediate for targeted imaging applications

Adair, C., Woods, M., Zhao, P., Pasha, A., Winter, P. M., Lanza, G. M., Athey, P., Sherry, A. D. & Kiefer, G. E., 2007, In: Contrast Media and Molecular Imaging. 2, 1, p. 55-58 4 p.

Research output: Contribution to journal › Article › peer-review

Open Access

27 Scopus citations

2008

Antiangiogenic Synergism of Integrin-Targeted Fumagillin Nanoparticles and Atorvastatin in Atherosclerosis

Winter, P. M., Caruthers, S. D., Zhang, H., Williams, T. A., Wickline, S. A. & Lanza, G. M., Sep 2008, In: JACC: Cardiovascular Imaging. 1, 5, p. 624-634 11 p.

Research output: Contribution to journal › Article › peer-review

Open Access

145 Scopus citations

Detection and quantification of angiogenesis in experimental valve disease with integrin-targeted nanoparticles and 19-fluorine MRI/MRS

Waters, E. A., Chen, J., Allen, J. S., Zhang, H., Lanza, G. M. & Wickline, S. A., 2008, In: Journal of Cardiovascular Magnetic Resonance. 10, 1, 43.

Research output: Contribution to journal › Article › peer-review

Open Access

56 Scopus citations

Detection of targeted perfluorocarbon nanoparticle binding using ¹⁹F diffusion weighted MR spectroscopy

Waters, E. A., Chen, J., Yang, X., Zhang, H., Neumann, R., Santeford, A., Arbeit, J., Lanza, G. M. & Wickline, S. A., Nov 2008, In: Magnetic resonance in medicine. 60, 5, p. 1232-1236 5 p.

Research output: Contribution to journal › Article › peer-review

Open Access

39 Scopus citations

Exploiting lipid raft transport with membrane targeted nanoparticles: A strategy for cytosolic drug delivery

Partlow, K. C., Lanza, G. M. & Wickline, S. A., Aug 2008, In: Biomaterials. 29, 23, p. 3367-3375 9 p.

Research output: Contribution to journal › Article › peer-review

99 Scopus citations

Gadolinium-modulated ¹⁹F signals from perfluorocarbon nanoparticles as a new strategy for molecular imaging

Neubauer, A. M., Myerson, J., Caruthers, S. D., Hockett, F. D., Winter, P. M., Chen, J., Gaffney, P. J., Robertson, J. D., Lanza, G. M. & Wickline, S. A., Nov 2008, In: Magnetic resonance in medicine. 60, 5, p. 1066-1072 7 p.

Research output: Contribution to journal › Article › peer-review

83 Scopus citations

Intramural delivery of rapamycin with αvβ3-targeted paramagnetic nanoparticles inhibits stenosis after balloon injury

Cyrus, T., Zhang, H., Allen, J. S., Williams, T. A., Hu, G., Caruthers, S. D., Wickline, S. A. & Lanza, G. M., May 2008, In: Arteriosclerosis, thrombosis, and vascular biology. 28, 5, p. 820-826 7 p.

Research output: Contribution to journal › Article › peer-review

83 Scopus citations

In vivo "hot spot" MR imaging of neural stem cells using fluorinated nanoparticles

Ruiz-Cabello, J., Walczak, P., Kedziorek, D. A., Chacko, V. P., Schmieder, A. H., Wickline, S. A., Lanza, G. M. & Bulte, J. W. M., Dec 2008, In: Magnetic resonance in medicine. 60, 6, p. 1506-1511 6 p.

Research output: Contribution to journal › Article › peer-review

141 Scopus citations

Ligand-directed nanobialys as theranostic agent for drug delivery and manganese-based magnetic resonance imaging of vascular targets

Pan, D., Caruthers, S. D., Hu, G., Senpan, A., Scott, M. J., Gaffney, P. J., Wickline, S. A. & Lanza, G. M., Jul 23 2008, In: Journal of the American Chemical Society. 130, 29, p. 9186-9187 2 p.

Research output: Contribution to journal › Article › peer-review

171 Scopus citations

Minute dosages of α_vβ₃-targeted fumagillin nanoparticles impair Vx-2 tumor angiogenesis and development in rabbits

Winter, P. M., Schmieder, A. H., Caruthers, S. D., Keene, J. L., Zhang, H., Wickline, S. A. & Lanza, G. M., Aug 2008, In: FASEB Journal. 22, 8, p. 2758-2767 10 p.

Research output: Contribution to journal › Article › peer-review

94 Scopus citations

Nanoparticle pharmacokinetic profiling in vivo using magnetic resonance imaging

Neubauer, A. M., Sim, H., Winter, P. M., Caruthers, S. D., Williams, T. A., Robertson, J. D., Sept, D., Lanza, G. M. & Wickline, S. A., Dec 2008, In: Magnetic resonance in medicine. 60, 6, p. 1353-1361 9 p.

Research output: Contribution to journal › Article › peer-review

Open Access

51 Scopus citations

New mechanisms for non-porative ultrasound stimulation of cargo delivery to cell cytosol with targeted perfluorocarbon nanoparticles

Soman, N. R., Marsh, J. N., Lanza, G. M. & Wickline, S. A., May 7 2008, In: Nanotechnology. 19, 18, 185102.

Research output: Contribution to journal › Article › peer-review

22 Scopus citations

Perfluorocarbon nanoparticles for molecular imaging and targeted therapeutics

Hughes, M., Caruthers, S., Tran, T., Marsh, J., Wallace, K., Cyrus, T., Partlow, K., Scott, M., Lijowski, M., Neubauer, A., Winter, P., Hu, G., Zhang, H., McCarthy, J., Maurizi, B., Allen, J., Caradine, C., Neumann, R., Arbeit, J., Lanza, G., & 1 othersWickline, S., Mar 2008, In: Proceedings of the IEEE. 96, 3, p. 397-415 19 p., 4446657.

Research output: Contribution to journal › Article › peer-review

16 Scopus citations

Synthesis and characterization of stable fluorocarbon nanostructures as drug delivery vehicles for cytolytic peptides

Soman, N. R., Lanza, G. M., Heuser, J. M., Schlesinger, P. H. & Wickline, S. A., Apr 2008, In: Nano Letters. 8, 4, p. 1131-1136 6 p.

Research output: Contribution to journal › Article › peer-review

124 Scopus citations

Three-dimensional MR mapping of angiogenesis with α₅β ₁(α_νβ₃)-targeted theranostic nanoparticles in the MDA-MB-435 xenograft mouse model

Schmieder, A. H., Caruthers, S. D., Zhang, H., Williams, T. A., Robertson, J. D., Wickline, S. A. & Lanza, G. M., Dec 2008, In: FASEB Journal. 22, 12, p. 4179-4189 11 p.

Research output: Contribution to journal › Article › peer-review

117 Scopus citations

2009

Anti-angiogenic perfluorocarbon nanoparticles for diagnosis and treatment of atherosclerosis

Caruthers, S. D., Cyrus, T., Winter, P. M., Wickline, S. A. & Lanza, G. M., Dec 1 2009, In: Wiley Interdisciplinary Reviews: Nanomedicine and Nanobiotechnology. 1, 3, p. 311-323 13 p.

Research output: Contribution to journal › Article › peer-review

48 Scopus citations

Application of renyi entropy for ultrasonic molecular imaging

Hughes, M. S., Marsh, J. N., Arbeit, J. M., Neumann, R. G., Fuhrhop, R. W., Wallace, K. D., Thomas, L., Smith, J., Agyem, K., Lanza, G. M., Wickline, S. A. & McCarthy, J. E., 2009, In: Journal of the Acoustical Society of America. 125, 5, p. 3141-3145 5 p.

Research output: Contribution to journal › Article › peer-review

30 Scopus citations

Conquering the dark side: Colloidal iron oxide nanoparticles

Senpan, A., Caruthers, S. D., Rhee, I., Mauro, N. A., Pan, D., Hu, G., Scott, M. J., Fuhrhop, R. W., Gaffney, P. J., Wickline, S. A. & Lanza, G. M., Dec 22 2009, In: ACS nano. 3, 12, p. 3917-3926 10 p.

Research output: Contribution to journal › Article › peer-review

81 Scopus citations

Detecting vascular biosignatures with a colloidal, radio-opaque polymeric nanoparticle

Pan, D., Williams, T. A., Senpan, A., Allen, J. S., Scott, M. J., Gaffney, P. J., Wickline, S. A. & Lanza, G. M., Oct 28 2009, In: Journal of the American Chemical Society. 131, 42, p. 15522-15527 6 p.

Research output: Contribution to journal › Article › peer-review

79 Scopus citations

Gregory Lanza

Research output

Search results