Gregory Lanza

2011

Thrombin-inhibiting perfluorocarbon nanoparticles provide a novel strategy for the treatment and magnetic resonance imaging of acute thrombosis

Myerson, J., He, L., Lanza, G., Tollefsen, D. & Wickline, S. A., Jul 2011, In: Journal of Thrombosis and Haemostasis. 9, 7, p. 1292-1300 9 p.

Research output: Contribution to journal › Article › peer-review

Open Access

87 Scopus citations

Use of smoothing splines for analysis of backscattered ultrasonic waveforms: Application to monitoring of steroid treatment of dystrophic mice

Hughes, M. S., Marsh, J. N., Agyem, K. F., McCarthy, J. E., Maurizi, B. N., Wickerhauser, M. V., Wallace, K. D., Lanza, G. M. & Wickline, S. A., Nov 2011, In: IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control. 58, 11, p. 2361-2369 9 p., 6071054.

Research output: Contribution to journal › Article › peer-review

8 Scopus citations

Variable antibody-dependent activation of complement by functionalized phospholipid nanoparticle surfaces

Pham, C. T. N., Mitchell, L. M., Huang, J. L., Lubniewski, C. M., Schall, O. F., Killgore, J. K., Pan, D., Wickline, S. A., Lanza, G. M. & Hourcade, D. E., Jan 7 2011, In: Journal of Biological Chemistry. 286, 1, p. 123-130 8 p.

Research output: Contribution to journal › Article › peer-review

Open Access

61 Scopus citations

2010

A facile synthesis of novel self-assembled gold nanorods designed for near-infrared imaging

Pan, D., Pramanik, M., Senpan, A., Wickline, S. A., Wang, L. V. & Lanza, G. M., Dec 2010, In: Journal of Nanoscience and Nanotechnology. 10, 12, p. 8118-8123 6 p.

Research output: Contribution to journal › Article › peer-review

Open Access

48 Scopus citations

An application of smoothing splines for molecular imaging of tumors using an improved calculation of a limiting form of Renyi entropy

Hughes, M. S., Marsh, J. N., Wallace, K. D., Lanza, G. M., Wickline, S. A., McCarthy, J. E., Wickerhauser, M. V. & Maurizi, B. N., 2010, 2010 IEEE International Ultrasonics Symposium, IUS 2010. p. 45-48 4 p. 5935961. (Proceedings - IEEE Ultrasonics Symposium).

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › peer-review

Angiogenesis imaging with vascular-constrained particles: The why and how

Lanza, G. M., Caruthers, S. D., Winter, P. M., Hughes, M. S., Schmieder, A. H., Hu, G. & Wickline, S. A., Aug 2010, In: European Journal of Nuclear Medicine and Molecular Imaging. 37, SUPPL. 1, p. S114-S126

Research output: Contribution to journal › Review article › peer-review

19 Scopus citations

Application of a limiting form of the Ŕnyi entropy for molecular imaging of tumors using a clinically relevant protocol

Marsh, J. N., Wallace, K. D., Lanza, G. M., Wickline, S. A., Hughes, M. S., McCarthy, J. E. & Wickerhauser, M. V., 2010, 2010 IEEE International Ultrasonics Symposium, IUS 2010. p. 53-56 4 p. 5935829. (Proceedings - IEEE Ultrasonics Symposium).

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › peer-review

7 Scopus citations

Application of a real-time, calculable limiting form of the Renyi entropy for molecular imaging of tumors

Marsh, J. N., Wallace, K. D., McCarthy, J. E., Wickerhauser, M. V., Maurizi, B. N., Lanza, G. M., Wickline, S. A. & Hughes, M. S., Aug 2010, In: IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control. 57, 8, p. 1890-1895 6 p., 5529480.

Research output: Contribution to journal › Article › peer-review

Open Access

9 Scopus citations

Assessment of tumor angiogenesis: Dynamic contrast-enhanced MRI with paramagnetic nanoparticles compared with Gd-DTPA in a rabbit Vx-2 tumor model

Kassner, A., Thornhill, R. E., Liu, F., Winter, P. M., Caruthers, S. D., Wickline, S. A. & Lanza, G. M., May 2010, In: Contrast Media and Molecular Imaging. 5, 3, p. 155-161 7 p.

Research output: Contribution to journal › Article › peer-review

9 Scopus citations

CION v2.0: A better way to T1 enhancement with iron oxides

Caruthers, S. D., Senpan, A., Pan, D., Hu, G., Wickline, S. A. & Lanza, G. M., 2010, In: Journal of Cardiovascular Magnetic Resonance. 12, SUPPL. 1, O57.

Research output: Contribution to journal › Article › peer-review

Open Access

Computed tomography in color: Nanok-enhanced spectral CT molecular imaging

Pan, D., Roessl, E., Schlomka, J. P., Caruthers, S. D., Senpan, A., Scott, M. J., Allen, J. S., Zhang, H., Hu, G., Gaffney, P. J., Choi, E. T., Rasche, V., Wickline, S. A., Proksa, R. & Lanza, G. M., Dec 10 2010, In: Angewandte Chemie - International Edition. 49, 50, p. 9635-9639 5 p.

Research output: Contribution to journal › Article › peer-review

Open Access

151 Scopus citations

Imaging atherosclerosis and vulnerable plaque

Sadeghi, M. M., Glover, D. K., Lanza, G. M., Fayad, Z. A. & Johnson, L. L., 2010, In: Journal of Nuclear Medicine. 51, SUPPL.1, p. 51S-65S

Research output: Contribution to journal › Review article › peer-review

Open Access

79 Scopus citations

Lipid membrane editing with peptide cargo linkers in cells and synthetic nanostructures

Pan, H., Myerson, J. W., Ivashyna, O., Soman, N. R., Marsh, J. N., Hood, J. L., Lanza, G. M., Schlesinger, P. H. & Wickline, S. A., Aug 2010, In: FASEB Journal. 24, 8, p. 2928-2937 10 p.

Research output: Contribution to journal › Article › peer-review

Open Access

30 Scopus citations

Mechanisms of nucleotide trafficking during siRNA delivery to endothelial cells using perfluorocarbon nanoemulsions

Kaneda, M. M., Sasaki, Y., Lanza, G. M., Milbrandt, J. & Wickline, S. A., Apr 2010, In: Biomaterials. 31, 11, p. 3079-3086 8 p.

Research output: Contribution to journal › Article › peer-review

Open Access

54 Scopus citations

MO‐D‐BRA‐01: Nano ‐ Cancer and Radiation Therapy

Khan, M., Lanza, G. & Miften, M., Jun 2010, In: Medical physics. 37, 6, p. 3338-3339 2 p.

Research output: Contribution to journal › Article › peer-review

MO‐D‐BRA‐02: Image‐Guided Drug Delivery Developments in Cancer

Lanza, G., Jun 2010, In: Medical physics. 37, 6, p. 3339 1 p.

Research output: Contribution to journal › Article › peer-review

Molecular imaging of angiogenic therapy in peripheral vascular disease with α_vβ₃-integrin-targeted nanoparticles

Winter, P. M., Caruthers, S. D., Allen, J. S., Cai, K., Williams, T. A., Lanza, G. M. & Wickline, S. A., Aug 2010, In: Magnetic resonance in medicine. 64, 2, p. 369-376 8 p.

Research output: Contribution to journal › Article › peer-review

Open Access

48 Scopus citations

MR angiogenesis imaging with Robo4- vs. α_Vβ ₃-targeted nanoparticles in a B16/F10 mouse melanoma model

Boles, K. S., Schmieder, A. H., Koch, A. W., Carano, R. A. D., Wu, Y., Caruthers, S. D., Tong, R. K., Stawicki, S., Hu, G., Scott, M. J., Zhang, H., Reynolds, B. A., Wickline, S. A. & Lanza, G. M., Nov 2010, In: FASEB Journal. 24, 11, p. 4262-4270 9 p.

Research output: Contribution to journal › Article › peer-review

32 Scopus citations

MR molecular imaging of angiogenesis using targeted perfluorocarbon nanoparticles

Caruthers, S. D., Winter, P. M., Wickline, S. A., Lanza, G. M. & Keupp, J., 2010, In: MedicaMundi. 54, 2, p. 5-13 9 p.

Research output: Contribution to journal › Article › peer-review

4 Scopus citations

MR molecular imaging of aortic angiogenesis

Cai, K., Caruthers, S. D., Huang, W., Williams, T. A., Zhang, H., Wickline, S. A., Lanza, G. M. & Winter, P. M., Aug 2010, In: JACC: Cardiovascular Imaging. 3, 8, p. 824-832 9 p.

Research output: Contribution to journal › Article › peer-review

Open Access

23 Scopus citations

Multi-resolution simultaneous 19F/1H 3D radial imaging for self-navigated respiratory motion-corrected and quantitative imaging

Caruthers, S. D., Keupp, J., Rahmer, J., Lanza, G. M. & Wickline, S. A., 2010, In: Journal of Cardiovascular Magnetic Resonance. 12, SUPPL. 1, O56.

Research output: Contribution to journal › Article › peer-review

Open Access

5 Scopus citations

Nanomedicine strategies for molecular targets with MRI and optical imaging

Pan, D., Caruthers, S. D., Chen, J., Winter, P. M., Senpan, A., Schmieder, A. H., Wickline, S. A. & Lanza, G. M., Mar 2010, In: Future medicinal chemistry. 2, 3, p. 471-490 20 p.

Research output: Contribution to journal › Review article › peer-review

Open Access

82 Scopus citations

Near infrared photoacoustic detection of sentinel lymph nodes with gold nanobeacons

Pan, D., Pramanik, M., Senpan, A., Ghosh, S., Wickline, S. A., Wang, L. V. & Lanza, G. M., May 2010, In: Biomaterials. 31, 14, p. 4088-4093 6 p.

Research output: Contribution to journal › Article › peer-review

Open Access

153 Scopus citations

Quantitative cardiovascular magnetic resonance for molecular imaging

Winter, P. M., Caruthers, S. D., Lanza, G. M. & Wickline, S. A., 2010, In: Journal of Cardiovascular Magnetic Resonance. 12, 1, 62.

Research output: Contribution to journal › Review article › peer-review

Open Access

17 Scopus citations

Quantitative magnetic resonance fluorine imaging: Today and tomorrow

Chen, J., Lanza, G. M. & Wickline, S. A., Jul 2010, In: Wiley Interdisciplinary Reviews: Nanomedicine and Nanobiotechnology. 2, 4, p. 431-440 10 p.

Research output: Contribution to journal › Review article › peer-review

Open Access

90 Scopus citations

Rationale for a nanomedicine approach to thrombolytic therapy.

Lanza, G. M., Marsh, J. N., Hu, G., Scott, M. J., Schmieder, A. H., Caruthers, S. D., Pan, D. & Wickline, S. A., Oct 2010, In: Stroke; a journal of cerebral circulation. 41, 10 Suppl, p. S42-44

Research output: Contribution to journal › Review article › peer-review

Open Access

28 Scopus citations

Synergistic effect of antiangiogenic nanotherapy combined with methotrexate in the treatment of experimental inflammatory arthritis

Zhou, H. F., Hu, G., Wickline, S. A., Lanza, G. M. & Pham, C. T., Sep 2010, In: Nanomedicine. 5, 7, p. 1065-1074 10 p.

Research output: Contribution to journal › Article › peer-review

Open Access

33 Scopus citations

Targeting of α _νβ ₃-integrins expressed on tumor tissue and neovasculature using fluorescent small molecules and nanoparticles

Akers, W. J., Zhang, Z., Berezin, M., Ye, Y., Agee, A., Guo, K., Fuhrhop, R. W., Wickline, S. A., Lanza, G. M. & Achilefu, S., Jul 2010, In: Nanomedicine. 5, 5, p. 715-726 12 p.

Research output: Contribution to journal › Article › peer-review

Open Access

36 Scopus citations

Theragnostics for tumor and plaque angiogenesis with perfluorocarbon nanoemulsions

Lanza, G. M., Winter, P. M., Caruthers, S. D., Hughes, M. S., Hu, G., Schmieder, A. H. & Wickline, S. A., Jun 2010, In: Angiogenesis. 13, 2, p. 189-202 14 p.

Research output: Contribution to journal › Review article › peer-review

Open Access

83 Scopus citations

TU‐C‐201C‐03: Next Generation of Imaging Platforms: Clinical Validation of Nanomedicine

Lanza, G., Jun 2010, In: Medical physics. 37, 6, p. 3387-3388 2 p.

Research output: Contribution to journal › Article › peer-review

2009

Anti-angiogenic perfluorocarbon nanoparticles for diagnosis and treatment of atherosclerosis

Caruthers, S. D., Cyrus, T., Winter, P. M., Wickline, S. A. & Lanza, G. M., Dec 1 2009, In: Wiley Interdisciplinary Reviews: Nanomedicine and Nanobiotechnology. 1, 3, p. 311-323 13 p.

Research output: Contribution to journal › Article › peer-review

48 Scopus citations

Application of renyi entropy for ultrasonic molecular imaging

Hughes, M. S., Marsh, J. N., Arbeit, J. M., Neumann, R. G., Fuhrhop, R. W., Wallace, K. D., Thomas, L., Smith, J., Agyem, K., Lanza, G. M., Wickline, S. A. & McCarthy, J. E., 2009, In: Journal of the Acoustical Society of America. 125, 5, p. 3141-3145 5 p.

Research output: Contribution to journal › Article › peer-review

Open Access

30 Scopus citations

Conquering the dark side: Colloidal iron oxide nanoparticles

Senpan, A., Caruthers, S. D., Rhee, I., Mauro, N. A., Pan, D., Hu, G., Scott, M. J., Fuhrhop, R. W., Gaffney, P. J., Wickline, S. A. & Lanza, G. M., Dec 22 2009, In: ACS nano. 3, 12, p. 3917-3926 10 p.

Research output: Contribution to journal › Article › peer-review

Open Access

83 Scopus citations

Detecting vascular biosignatures with a colloidal, radio-opaque polymeric nanoparticle

Pan, D., Williams, T. A., Senpan, A., Allen, J. S., Scott, M. J., Gaffney, P. J., Wickline, S. A. & Lanza, G. M., Oct 28 2009, In: Journal of the American Chemical Society. 131, 42, p. 15522-15527 6 p.

Research output: Contribution to journal › Article › peer-review

Open Access

80 Scopus citations

High sensitivity: High-resolution SPECT-CT/MR molecular imaging of angiogenesis in the Vx2 model

Lijowski, M., Caruthers, S., Hu, G., Zhang, H., Scott, M. J., Williams, T., Erpelding, T., Schmieder, A. H., Kiefer, G., Gulyas, G., Athey, P. S., Gaffney, P. J., Wickline, S. A. & Lanza, G. M., Jan 2009, In: Investigative Radiology. 44, 1, p. 15-22 8 p.

Research output: Contribution to journal › Article › peer-review

76 Scopus citations

Magnetic nanoparticles for early detection of cancer by magnetic resonance imaging

Lin, W., Hyeon, T., Lanza, G. M., Zhang, M. & Meade, T. J., Jun 2009, In: MRS Bulletin. 34, 6, p. 441-448 8 p.

Research output: Contribution to journal › Article › peer-review

59 Scopus citations

Molecularly targeted nanocarriers deliver the cytolytic peptide melittin specifically to tumor cells in mice, reducing tumor growth

Soman, N. R., Baldwin, S. L., Hu, G., Marsh, J. N., Lanza, G. M., Heuser, J. E., Arbeit, J. M., Wickline, S. A. & Schlesinger, P. H., Sep 1 2009, In: Journal of Clinical Investigation. 119, 9, p. 2830-2842 13 p.

Research output: Contribution to journal › Article › peer-review

Open Access

261 Scopus citations

Molecular photoacoustic tomography with colloidal nanobeacons

Pan, D., Pramanik, M., Senpan, A., Yang, X., Song, K. H., Scott, M. J., Zhang, H., Gaffney, P. J., Wickline, S. A., Wang, L. V. & Lanza, G. M., May 25 2009, In: Angewandte Chemie - International Edition. 48, 23, p. 4170-4173 4 p.

Research output: Contribution to journal › Article › peer-review

Open Access

91 Scopus citations

Nanomedicine: Perspective and promises with ligand-directed molecular imaging

Pan, D., Lanza, G. M., Wickline, S. A. & Caruthers, S. D., May 2009, In: European Journal of Radiology. 70, 2, p. 274-285 12 p.

Research output: Contribution to journal › Article › peer-review

98 Scopus citations

Paracrine induction of endothelium by tumor exosomes

Hood, J. L., Pan, H., Lanza, G. M. & Wickline, S. A., Nov 2009, In: Laboratory Investigation. 89, 11, p. 1317-1328 12 p.

Research output: Contribution to journal › Article › peer-review

Open Access

240 Scopus citations

Perfluorocarbon Nanoemulsions for quantitative molecular imaging and targeted therapeutics

Kaneda, M. M., Caruthers, S., Lanza, G. M. & Wickline, S. A., Oct 2009, In: Annals of biomedical engineering. 37, 10, p. 1922-1933 12 p.

Research output: Contribution to journal › Article › peer-review

Open Access

160 Scopus citations

Real-time calculation of a limiting form of the Renyi entropy applied to detection of subtle changes in scattering architecture

Hughes, M. S., McCarthy, J. E., Wickerhauser, M. V., Marsh, J. N., Arbeit, J. M., Fuhrhop, R. W., Wallace, K. D., Thomas, T., Smith, J., Agyem, K., Lanza, G. M. & Wickline, S. A., 2009, In: Journal of the Acoustical Society of America. 126, 5, p. 2350-2358 9 p.

Research output: Contribution to journal › Article › peer-review

Open Access

14 Scopus citations

Real-time calculation of a limiting form of the renyi entropy for detection of subtle changes in scattering architecture

Hughes, M. S., Marsh, J. N., Arbeit, J. M., Fuhrhop, R. W., Wallace, K. D., Thomas, T., Smith, J., Agyem, K., Lanza, G. M., Wickline, S. A., McCarthy, J. E. & Wickerhauser, M. V., Dec 1 2009, 2009 IEEE International Ultrasonics Symposium and Short Courses, IUS 2009. 5441843. (Proceedings - IEEE Ultrasonics Symposium).

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › peer-review

Renal vascular inflammation induced by Western diet in ApoE-null mice quantified by ¹⁹F NMR of VCAM-1 targeted nanobeacons

Southworth, R., Kaneda, M., Chen, J., Zhang, L., Zhang, H., Yang, X., Razavi, R., Lanza, G. & Wickline, S. A., Sep 2009, In: Nanomedicine: Nanotechnology, Biology, and Medicine. 5, 3, p. 359-367 9 p.

Research output: Contribution to journal › Article › peer-review

Open Access

56 Scopus citations

Sensitive and efficient detection of thrombus with fibrin-specific manganese nanocolloids

Pan, D., Senpan, A., Caruthers, S. D., Williams, T. A., Scott, M. J., Gaffney, P. J., Wickline, S. A. & Lanza, G. M., 2009, In: Chemical Communications. 22, p. 3234-3236 3 p.

Research output: Contribution to journal › Article › peer-review

Open Access

46 Scopus citations

Shannon entropy: A specular echo-insensitive imaging metric showing myocardial anisotropy

Cheng, Y. J., Marsh, J. N., Wallace, K. D., Zhang, L., Lanza, G. M., Wickline, S. A. & Hughes, M. S., 2009, 2009 IEEE International Ultrasonics Symposium and Short Courses, IUS 2009. 5441837. (Proceedings - IEEE Ultrasonics Symposium).

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › peer-review

Ultrasonic characterization of backscatter from human cancellous bone with a Renyi entopy metric: Correlation with X-ray bone mineral density

Wallace, K. D., Hoffmeister, B. K., Thomas, L., Kaste, S. C., Lanza, G. M. & Wickline, S. A., 2009, 2009 IEEE International Ultrasonics Symposium and Short Courses, IUS 2009. Institute of Electrical and Electronics Engineers Inc., p. 542-545 4 p. 5441607. (Proceedings - IEEE Ultrasonics Symposium).

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › peer-review

3 Scopus citations

α_vβ₃-Targeted nanotherapy suppresses inflammatory arthritis in mice

Zhou, H. F., Chan, H. W., Wickline, S. A., Lanza, G. M. & Pham, C. T. N., Sep 2009, In: FASEB Journal. 23, 9, p. 2978-2985 8 p.

Research output: Contribution to journal › Article › peer-review

Open Access

78 Scopus citations

2008

Antiangiogenic Synergism of Integrin-Targeted Fumagillin Nanoparticles and Atorvastatin in Atherosclerosis

Winter, P. M., Caruthers, S. D., Zhang, H., Williams, T. A., Wickline, S. A. & Lanza, G. M., Sep 2008, In: JACC: Cardiovascular Imaging. 1, 5, p. 624-634 11 p.

Research output: Contribution to journal › Article › peer-review

Open Access

149 Scopus citations

Detection and quantification of angiogenesis in experimental valve disease with integrin-targeted nanoparticles and 19-fluorine MRI/MRS

Waters, E. A., Chen, J., Allen, J. S., Zhang, H., Lanza, G. M. & Wickline, S. A., 2008, In: Journal of Cardiovascular Magnetic Resonance. 10, 1, 43.

Research output: Contribution to journal › Article › peer-review

Open Access

57 Scopus citations

Gregory Lanza

Research output

Search results