Greg Bowman

Associate Professor of Biochemistry and Molecular Biophysics, Adjunct Assistant Professor of Chemistry, Associate Director of the CSELS

    • 4422 Citations
    20052020

    Research output per year

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    Personal profile

    Research interests

    The Bowman lab is interested in combining computer simulations and experiments to reveal cryptic pockets that are not easily identified by conventional structural techniques and then exploiting them to combat antibiotic resistant infections.

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    Research Output

    Antagonism between substitutions in β-lactamase explains a path not taken in the evolution of bacterial drug resistance

    Brown, C. A., Hu, L., Sun, Z., Patel, M. P., Singh, S., Porter, J. R., Sankaran, B., Venkataram Prasad, B. V., Bowman, G. R. & Palzkill, T., May 22 2020, In : Journal of Biological Chemistry. 295, 21, p. 7376-7390 15 p.

    Research output: Contribution to journalArticle

  • Computing and optimizing over all fixed-points of discrete systems on large networks

    Riehl, J. R., Zimmerman, M. I., Singh, M. F., Bowman, G. R. & Ching, S. N., Sep 1 2020, In : Journal of the Royal Society, Interface. 17, 170, p. 20200126 1 p.

    Research output: Contribution to journalArticle

  • Conformational distributions of isolated myosin motor domains encode their mechanochemical properties

    Porter, J. R., Meller, A., Zimmerman, M. I., Greenberg, M. J. & Bowman, G. R., May 2020, In : eLife. 9, e55132.

    Research output: Contribution to journalArticle

    Open Access
  • Investigating Cryptic Binding Sites by Molecular Dynamics Simulations

    Kuzmanic, A., Bowman, G. R., Juarez-Jimenez, J., Michel, J. & Gervasio, F. L., 2020, (Accepted/In press) In : ACS Applied Materials and Interfaces.

    Research output: Contribution to journalArticle

  • 3 Scopus citations

    Spatial and temporal alterations in protein structure by EGF regulate cryptic cysteine oxidation

    Behring, J. B., van der Post, S., Mooradian, A. D., Egan, M. J., Zimmerman, M. I., Clements, J. L., Bowman, G. R. & Held, J. M., Jan 21 2020, In : Science signaling. 13, 615, eaay7315.

    Research output: Contribution to journalArticle

  • 4 Scopus citations