Research output per year
Research output per year
Personal profile
Research interests
The Bowman lab is interested in combining computer simulations and experiments to reveal cryptic pockets that are not easily identified by conventional structural techniques and then exploiting them to combat antibiotic resistant infections.
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Dive into the research topics where Greg Bowman is active. These topic labels come from the works of this person. Together they form a unique fingerprint.
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A cryptic pocket in Ebola VP35 allosterically controls RNA binding
Cruz, M. A., Frederick, T. E., Mallimadugula, U. L., Singh, S., Vithani, N., Zimmerman, M. I., Porter, J. R., Moeder, K. E., Amarasinghe, G. K. & Bowman, G. R., Dec 2022, In: Nature communications. 13, 1, 2269.Research output: Contribution to journal › Article › peer-review
Open Access -
Deep learning the structural determinants of protein biochemical properties by comparing structural ensembles with DiffNets
Ward, M. D., Zimmerman, M. I., Meller, A., Chung, M., Swamidass, S. J. & Bowman, G. R., Dec 2021, In: Nature communications. 12, 1, 3023.Research output: Contribution to journal › Article › peer-review
Open Access11 Scopus citations -
Editorial: Experiments and Simulations: A Pas de Deux to Unravel Biological Function
Topf, M., Rosta, E., Bowman, G. R. & Bonomi, M., Nov 29 2021, In: Frontiers in Molecular Biosciences. 8, 799406.Research output: Contribution to journal › Editorial
Open Access -
Naturally Occurring Genetic Variants in the Oxytocin Receptor Alter Receptor Signaling Profiles
Malik, M., Ward, M. D., Fang, Y., Porter, J. R., Zimmerman, M. I., Koelblen, T., Roh, M., Frolova, A. I., Burris, T. P., Bowman, G. R., Imoukhuede, P. I. & England, S. K., Oct 8 2021, In: ACS Pharmacology and Translational Science. 4, 5, p. 1543-1555 13 p.Research output: Contribution to journal › Article › peer-review
Open Access -
Opening of a cryptic pocket in β-lactamase increases penicillinase activity
Knoverek, C. R., Mallimadugula, U. L., Singh, S., Rennella, E., Frederick, T. E., Yuwen, T., Raavicharla, S., Kay, L. E. & Bowman, G. R., Nov 23 2021, In: Proceedings of the National Academy of Sciences of the United States of America. 118, 47, e2106473118.Research output: Contribution to journal › Article › peer-review
Open Access