Research output per year
Research output per year
Personal profile
Research interests
The epigenetic regulation of hematopoietic stem cell function and the impact of mutations in the epigenetic machinery in hematopoietic disease
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Dive into the research topics where Grant Challen is active. These topic labels come from the works of this person. Together they form a unique fingerprint.
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Research output
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Clonal hematopoiesis: mechanisms driving dominance of stem cell clones
Challen, G. A. & Goodell, M. A., Oct 1 2020, In: Blood. 136, 14, p. 1590-1598 9 p.Research output: Contribution to journal › Review article › peer-review
Open Access3 Scopus citations -
Divergent Effects of Dnmt3a and Tet2 Mutations on Hematopoietic Progenitor Cell Fitness
Ostrander, E. L., Kramer, A. C., Mallaney, C., Celik, H., Koh, W. K., Fairchild, J., Haussler, E., Zhang, C. R. C. & Challen, G. A., Apr 14 2020, In: Stem Cell Reports. 14, 4, p. 551-560 10 p.Research output: Contribution to journal › Article › peer-review
Open Access12 Scopus citations -
Interferon regulatory factor 4 as a therapeutic target in adult T-cell leukemia lymphoma
Rauch, D. A., Olson, S. L., Harding, J. C., Sundaramoorthi, H., Kim, Y., Zhou, T., MacLeod, A. R., Challen, G. & Ratner, L., Aug 28 2020, In: Retrovirology. 17, 1, 27.Research output: Contribution to journal › Article › peer-review
Open Access1 Scopus citations -
Radiation induces iatrogenic immunosuppression by indirectly affecting hematopoiesis in bone marrow
Kapoor, V., Collins, A., Griffith, K., Ghosh, S., Wong, N., Wang, X., Challen, G. A., Krambs, J., Link, D., Hallahan, D. E. & Thotala, D., May 12 2020, In: Oncotarget. 11, 19, p. 1681-1690 10 p.Research output: Contribution to journal › Article › peer-review
Open Access -
TGFβR-SMAD3 Signaling Induces Resistance to PARP Inhibitors in the Bone Marrow Microenvironment
Le, B. V., Podszywalow-Bartnicka, P., Maifrede, S., Sullivan-Reed, K., Nieborowska-Skorska, M., Golovine, K., Yao, J. C., Nejati, R., Cai, K. Q., Caruso, L. B., Swatler, J., Dabrowski, M., Lian, Z., Valent, P., Paietta, E. M., Levine, R. L., Fernandez, H. F., Tallman, M. S., Litzow, M. R., Huang, J. & 6 others, , Oct 6 2020, In: Cell Reports. 33, 1, 108221.Research output: Contribution to journal › Article › peer-review
Open Access1 Scopus citations