Research output per year
Research output per year
- 24 results
Search results
-
2018
Transient PP2A inhibition alleviates normal tissue stem cell susceptibility to cell death during radiotherapy
Fabbrizi, M. R., Meyer, B., Misri, S., Raj, S., Zobel, C. L., Hallahan, D. E. & Sharma, G. G., Jan 1 2018, In: Cell Death and Disease. 9, 5, 492.Research output: Contribution to journal › Article › peer-review
Open Access10 Scopus citations -
2016
Histone H3 Lysine 9 Acetylation Obstructs ATM Activation and Promotes Ionizing Radiation Sensitivity in Normal Stem Cells
Meyer, B., Fabbrizi, M. R., Raj, S., Zobel, C. L., Hallahan, D. E. & Sharma, G. G., Dec 13 2016, In: Stem Cell Reports. 7, 6, p. 1013-1022 10 p.Research output: Contribution to journal › Article › peer-review
Open Access32 Scopus citations -
Unique epigenetic influence of H2AX phosphorylation and H3K56 acetylation on normal stem cell radioresponses
Jacobs, K. M., Misri, S., Meyer, B., Raj, S., Zobel, C. L., Sleckman, B. P., Hallahan, D. E. & Sharma, G. G., Apr 15 2016, In: Molecular biology of the cell. 27, 8, p. 1332-1345 14 p.Research output: Contribution to journal › Article › peer-review
Open Access24 Scopus citations -
2013
Genome-wide distribution of histone H4 Lysine 16 acetylation sites and their relationship to gene expression
Horikoshi, N., Kumar, P., Sharma, G. G., Chen, M., Hunt, C. R., Westover, K., Chowdhury, S. & Pandita, T. K., Apr 12 2013, In: Genome Integrity. 4, 1, 3.Research output: Contribution to journal › Article › peer-review
Open Access44 Scopus citations -
2011
H2AX prevents CtIP-mediated DNA end resection and aberrant repair in G1-phase lymphocytes
Helmink, B. A., Tubbs, A. T., Dorsett, Y., Bednarski, J. J., Walker, L. M., Feng, Z., Sharma, G. G., McKinnon, P. J., Zhang, J., Bassing, C. H. & Sleckman, B. P., Jan 13 2011, In: Nature. 469, 7329, p. 245-250 6 p.Research output: Contribution to journal › Article › peer-review
Open Access124 Scopus citations -
Rad52 inactivation is synthetically lethal with BRCA2 deficiency
Feng, Z., Scott, S. P., Bussen, W., Sharma, G. G., Guo, G., Pandita, T. K. & Powell, S. N., Jan 11 2011, In: Proceedings of the National Academy of Sciences of the United States of America. 108, 2, p. 686-691 6 p.Research output: Contribution to journal › Article › peer-review
Open Access280 Scopus citations -
2010
MOF and histone H4 acetylation at lysine 16 are critical for DNA damage response and double-strand break repair
Sharma, G. G., So, S., Gupta, A., Kumar, R., Cayrou, C., Avvakumov, N., Bhadra, U., Pandita, R. K., Porteus, M. H., Chen, D. J., Cote, J. & Pandita, T. K., Jul 2010, In: Molecular and cellular biology. 30, 14, p. 3582-3595 14 p.Research output: Contribution to journal › Article › peer-review
Open Access269 Scopus citations -
2009
MRN complex function in the repair of chromosomal Rag-mediated DNA double-strand breaks
Helmink, B. A., Bredemeyer, A. L., Lee, B. S., Huang, C. Y., Sharma, G. G., Walker, L. M., Bednarski, J. J., Lee, W. L., Pandita, T. K., Bassing, C. H. & Sleckman, B. P., Mar 16 2009, In: Journal of Experimental Medicine. 206, 3, p. 669-679 11 p.Research output: Contribution to journal › Article › peer-review
Open Access75 Scopus citations -
2008
HP1 -β is required for development of the cerebral neocortex and neuromuscular junctions
Aucott, R., Bullwinkel, J., Yu, Y., Shi, W., Billur, M., Brown, J. P., Menzel, U., Kioussis, D., Wang, G., Reisert, I., Weimer, J., Pandita, R. K., Sharma, G. G., Pandita, T. K., Fundele, R. & Singh, P. B., Nov 17 2008, In: Journal of Cell Biology. 183, 4, p. 597-606 10 p.Research output: Contribution to journal › Article › peer-review
Open Access90 Scopus citations -
Single-stranded DNA-binding protein hSSB1 is critical for genomic stability
Richard, D. J., Bolderson, E., Cubeddu, L., Wadsworth, R. I. M., Savage, K., Sharma, G. G., Nicolette, M. L., Tsvetanov, S., McIlwraith, M. J., Pandita, R. K., Takeda, S., Hay, R. T., Gautier, J., West, S. C., Paull, T. T., Pandita, T. K., White, M. F. & Khanna, K. K., May 29 2008, In: Nature. 453, 7195, p. 677-681 5 p.Research output: Contribution to journal › Article › peer-review
216 Scopus citations -
The mammalian ortholog of Drosophila MOF that acetylates histone H4 lysine 16 is essential for embryogenesis and oncogenesis
Gupta, A., Guerin-Peyrou, T. G., Sharma, G. G., Park, C., Agarwal, M., Ganju, R. K., Pandita, S., Choi, K., Sukumar, S., Pandita, R. K., Ludwig, T. & Pandita, T. K., Jan 2008, In: Molecular and cellular biology. 28, 1, p. 397-409 13 p.Research output: Contribution to journal › Article › peer-review
Open Access192 Scopus citations -
2007
A role for the HOXB7 homeodomain protein in DNA repair
Rubin, E., Wu, X., Zhu, T., Cheung, J. C. Y., Chen, H., Lorincz, A., Pandita, R. K., Sharma, G. G., Hyo, C. H., Gasson, J., Hanakahi, L. A., Pandita, T. K. & Sukumar, S., Feb 15 2007, In: Cancer research. 67, 4, p. 1527-1535 9 p.Research output: Contribution to journal › Article › peer-review
77 Scopus citations -
Defects in coding joint formation in vivo in developing ATM-deficient B and T lymphocytes
Huang, C. Y., Sharma, G. G., Walker, L. M., Bassing, C. H., Pandita, T. K. & Sleckman, B. P., Jun 11 2007, In: Journal of Experimental Medicine. 204, 6, p. 1371-1381 11 p.Research output: Contribution to journal › Article › peer-review
Open Access45 Scopus citations -
2006
ATM stabilizes DNA double-strand-break complexes during V(D)J recombination
Bredemeyer, A. L., Sharma, G. G., Huang, C. Y., Helmink, B. A., Walker, L. M., Khor, K. C., Nuskey, B., Sullivan, K. E., Pandita, T. K., Bassing, C. H. & Sleckman, B. P., Jul 27 2006, In: Nature. 442, 7101, p. 466-470 5 p.Research output: Contribution to journal › Article › peer-review
333 Scopus citations -
Mammalian Rad9 plays a role in telomere stability, S- and G 2-phase-specific cell survival, and homologous recombinational repair
Pandita, R. K., Sharma, G. G., Laszlo, A., Hopkins, K. M., Davey, S., Chakhparonian, M., Gupta, A., Wellinger, R. J., Zhang, J., Powell, S. N., Roti Roti, J. L., Lieberman, H. B. & Pandita, T. K., Mar 2006, In: Molecular and cellular biology. 26, 5, p. 1850-1864 15 p.Research output: Contribution to journal › Article › peer-review
120 Scopus citations -
2005
Cdt1 transgenic mice develop lymphoblastic lymphoma in the absence of p53
Seo, J., Chung, Y. S., Sharma, G. G., Moon, E., Burack, W. R., Pandita, T. K. & Choi, K., Dec 8 2005, In: Oncogene. 24, 55, p. 8176-8186 11 p.Research output: Contribution to journal › Article › peer-review
71 Scopus citations -
Impaired genomic stability and increased oxidative stress exacerbate different features of Ataxia-telangiectasia
Ziv, S., Brenner, O., Amariglio, N., Smorodinsky, N. I., Galron, R., Carrion, D. V., Zhang, W., Sharma, G. G., Pandita, R. K., Agarwal, M., Elkon, R., Katzin, N., Bar-Am, I., Pandita, T. K., Kucherlapati, R., Rechavi, G., Shiloh, Y. & Barzilai, A., Oct 2005, In: Human molecular genetics. 14, 19, p. 2929-2943 15 p.Research output: Contribution to journal › Article › peer-review
Open Access26 Scopus citations -
Involvement of human MOF in ATM function
Gupta, A., Sharma, G. G., Young, C. S. H., Agarwal, M., Smith, E. R., Paull, T. T., Lucchesi, J. C., Khanna, K. K., Ludwig, T. & Pandita, T. K., Jun 2005, In: Molecular and cellular biology. 25, 12, p. 5292-5305 14 p.Research output: Contribution to journal › Article › peer-review
Open Access194 Scopus citations -
2004
Genomic Instability and Enhanced Radiosensitivity in Hsp70.1-and Hsp70.3 -Deficient Mice
Hunt, C. R., Dix, D. J., Sharma, G. G., Pandita, R. K., Gupta, A., Funk, M. & Pandita, T. K., Jan 2004, In: Molecular and cellular biology. 24, 2, p. 899-911 13 p.Research output: Contribution to journal › Article › peer-review
207 Scopus citations -
2003
hTERT associates with human telomeres and enhances genomic stability and DNA repair
Sharma, G. G., Gupta, A., Wang, H., Scherthan, H., Dhar, S., Gandhi, V., Iliakis, G., Shay, J. W., Young, C. S. H. & Pandita, T. K., Jan 9 2003, In: Oncogene. 22, 1, p. 131-146 16 p.Research output: Contribution to journal › Article › peer-review
227 Scopus citations -
Human Heterochromatin Protein 1 Isoforms HP1Hsα and HP1Hsβ Interfere with hTERT-Telomere Interactions and Correlate with Changes in Cell Growth and Response to Ionizing Radiation
Sharma, G. G., Hwang, K. K., Pandita, R. K., Gupta, A., Dhar, S., Parenteau, J., Agarwal, M., Worman, H. J., Wellinger, R. J. & Pandita, T. K., Nov 2003, In: Molecular and cellular biology. 23, 22, p. 8363-8376 14 p.Research output: Contribution to journal › Article › peer-review
Open Access84 Scopus citations -
Telomere stability correlates with longevity of human beings exposed to ionizing radiations.
Sharma, G. G., Hall, E. J., Dhar, S., Gupta, A., Rao, P. H. & Pandita, T. K., 2003, In: Oncology reports. 10, 6, p. 1733-1736 4 p.Research output: Contribution to journal › Article › peer-review
27 Scopus citations -
2001
Spontaneously immortalized cell lines obtained from adult Atm null mice retain sensitivity to ionizing radiation and exhibit a mutational pattern suggestive of oxidative stress
Gage, B. M., Alroy, D., Shin, C. Y., Ponomareva, O. N., Dhar, S., Sharma, G. G., Pandita, T. K., Thayer, M. J. & Turker, M. S., Jul 19 2001, In: Oncogene. 20, 32, p. 4291-4297 7 p.Research output: Contribution to journal › Article › peer-review
Open Access21 Scopus citations -
1998
Unusual chromosomal organization of telomeric sequences and expeditious karyotypic differentiation in the recently evolved Mus terricolor complex
Sharma, G. G. & Sharma, T., 1998, In: Cytogenetics and cell genetics. 80, 1-4, p. 204-208 5 p.Research output: Contribution to journal › Article › peer-review
12 Scopus citations