Research output per year
Research output per year
- 1 - 50 out of 116 results
Search results
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2024
Cardiometabolic characteristics of people with metabolically healthy and unhealthy obesity
Petersen, M. C., Smith, G. I., Palacios, H. H., Farabi, S. S., Yoshino, M., Yoshino, J., Cho, K., Davila-Roman, V. G., Shankaran, M., Barve, R. A., Yu, J., Stern, J. H., Patterson, B. W., Hellerstein, M. K., Shulman, G. I., Patti, G. J. & Klein, S., Apr 2 2024, In: Cell metabolism. 36, 4, p. 745-761.e5Research output: Contribution to journal › Article › peer-review
Open Access14 Scopus citations -
Circadian regulation of MGMT expression and promoter methylation underlies daily rhythms in TMZ sensitivity in glioblastoma
Gonzalez-Aponte, M. F., Damato, A. R., Trebucq, L. L., Simon, T., Cárdenas-García, S. P., Cho, K., Patti, G. J., Golombek, D. A., Chiesa, J. J., Rubin, J. B. & Herzog, E. D., Feb 2024, In: Journal of Neuro-Oncology. 166, 3, p. 419-430 12 p.Research output: Contribution to journal › Article › peer-review
4 Scopus citations -
DDR2-regulated arginase activity in ovarian cancer-associated fibroblasts promotes collagen production and tumor progression
Akinjiyan, F. A., Ibitoye, Z., Zhao, P., Shriver, L. P., Patti, G. J., Longmore, G. D. & Fuh, K. C., Jan 12 2024, In: Oncogene. 43, 3, p. 189-201 13 p.Research output: Contribution to journal › Article › peer-review
Open Access10 Scopus citations -
Discovery and Identification of Three Homocysteine Metabolites by Chemical Derivatization and Mass Spectrometry Fragmentation
Agongo, J., Grady, S. F., Cho, K., Patti, G. J., Bythell, B. J., Arnatt, C. K. & Edwards, J. L., Jul 23 2024, In: Analytical Chemistry. 96, 29, p. 11639-11643 5 p.Research output: Contribution to journal › Article › peer-review
1 Scopus citations -
HTRA1 disaggregates α-synuclein amyloid fibrils and converts them into non-toxic and seeding incompetent species
Chen, S., Puri, A., Bell, B., Fritsche, J., Palacios, H. H., Balch, M., Sprunger, M. L., Howard, M. K., Ryan, J. J., Haines, J. N., Patti, G. J., Davis, G. & Jackrel, M. E., Dec 2024, In: Nature communications. 15, 1, 2436.Research output: Contribution to journal › Article › peer-review
Open Access1 Scopus citations -
Inducing vulnerability to InhA inhibition restores isoniazid susceptibility in drug-resistant Mycobacterium tuberculosis
Harrison, G. A., Wang, E. R., Cho, K., Mreyoud, Y., Sarkar, S., Almqvist, F., Patti, G. J. & Stallings, C. L., Mar 2024, In: mBio. 15, 3Research output: Contribution to journal › Article › peer-review
Open Access -
Investigating post-traumatic syringomyelia and local fluid osmoregulation via a rat model
Pukale, D. D., Adkins-Travis, K., Aryal, S. R., Shriver, L. P., Patti, G. J. & Leipzig, N. D., Dec 2024, In: Fluids and barriers of the CNS. 21, 1, 19.Research output: Contribution to journal › Article › peer-review
Open Access -
Metabolite Study and Structural Authentication for the First-in-Human Use Sphingosine-1-phosphate Receptor 1 Radiotracer
Qiu, L., Jiang, H., Cho, K., Yu, Y., Jones, L. A., Huang, T., Perlmutter, J. S., Gropler, R. J., Brier, M. R., Patti, G. J., Benzinger, T. L. S. & Tu, Z., May 1 2024, In: ACS Chemical Neuroscience. 15, 9, p. 1882-1892 11 p.Research output: Contribution to journal › Article › peer-review
1 Scopus citations -
Predicting Collision Cross-Section Values for Small Molecules through Chemical Class-Based Multimodal Graph Attention Network
Wang, C., Yuan, C., Wang, Y., Shi, Y., Zhang, T. & Patti, G. J., Aug 26 2024, In: Journal of Chemical Information and Modeling. 64, 16, p. 6305-6315 11 p.Research output: Contribution to journal › Article › peer-review
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2023
A metabolomic signature of the APOE2 allele
Sebastiani, P., Song, Z., Ellis, D., Tian, Q., Schwaiger-Haber, M., Stancliffe, E., Lustgarten, M. S., Funk, C. C., Baloni, P., Yao, C. H., Joshi, S., Marron, M. M., Gurinovich, A., Li, M., Leshchyk, A., Xiang, Q., Andersen, S. L., Feitosa, M. F., Ukraintseva, S. & Soerensen, M. & 10 others, , Feb 2023, In: GeroScience. 45, 1, p. 415-426 12 p.Research output: Contribution to journal › Article › peer-review
Open Access4 Scopus citations -
BAP1 promotes osteoclast function by metabolic reprogramming
Rohatgi, N., Zou, W., Li, Y., Cho, K., Collins, P. L., Tycksen, E., Pandey, G., DeSelm, C. J., Patti, G. J., Dey, A. & Teitelbaum, S. L., Dec 2023, In: Nature communications. 14, 1, 5923.Research output: Contribution to journal › Article › peer-review
Open Access6 Scopus citations -
Cytosolic and mitochondrial NADPH fluxes are independently regulated
Niu, X., Stancliffe, E., Gelman, S. J., Wang, L., Schwaiger-Haber, M., Rowles, J. L., Shriver, L. P. & Patti, G. J., Jul 2023, In: Nature Chemical Biology. 19, 7, p. 837-845 9 p.Research output: Contribution to journal › Article › peer-review
16 Scopus citations -
Effects of hepatic mitochondrial pyruvate carrier deficiency on de novo lipogenesis and gluconeogenesis in mice
Yiew, N. K. H., Deja, S., Ferguson, D., Cho, K., Jarasvaraparn, C., Jacome-Sosa, M., Lutkewitte, A. J., Mukherjee, S., Fu, X., Singer, J. M., Patti, G. J., Burgess, S. C. & Finck, B. N., Nov 17 2023, In: iScience. 26, 11, 108196.Research output: Contribution to journal › Article › peer-review
Open Access2 Scopus citations -
Hyperammonaemia disrupts daily rhythms reversibly by elevating glutamate in the central circadian pacemaker
Granados-Fuentes, D., Cho, K., Patti, G. J., Costa, R., Herzog, E. D. & Montagnese, S., Mar 2023, In: Liver International. 43, 3, p. 673-683 11 p.Research output: Contribution to journal › Article › peer-review
Open Access2 Scopus citations -
Mitochondrial pyruvate carrier inhibition initiates metabolic crosstalk to stimulate branched chain amino acid catabolism
Ferguson, D., Eichler, S. J., Yiew, N. K. H., Colca, J. R., Cho, K., Patti, G. J., Shew, T. M., Lutkewitte, A. J., Mukherjee, S., McCommis, K. S., Niemi, N. M. & Finck, B. N., Apr 2023, In: Molecular Metabolism. 70, 101694.Research output: Contribution to journal › Article › peer-review
Open Access20 Scopus citations -
Mitochondrial pyruvate metabolism and glutaminolysis toggle steady-state and emergency myelopoiesis
Pizzato, H. A., Wang, Y., Wolfgang, M. J., Finck, B. N., Patti, G. J. & Bhattacharya, D., Sep 4 2023, In: The Journal of experimental medicine. 220, 9Research output: Contribution to journal › Article › peer-review
Open Access2 Scopus citations -
MPI-VGAE: protein-metabolite enzymatic reaction link learning by variational graph autoencoders
Wang, C., Yuan, C., Wang, Y., Chen, R., Shi, Y., Zhang, T., Xue, F., Patti, G. J., Wei, L. & Hou, Q., Jul 1 2023, In: Briefings in Bioinformatics. 24, 4, bbad189.Research output: Contribution to journal › Article › peer-review
Open Access3 Scopus citations -
PeakDetective: A Semisupervised Deep Learning-Based Approach for Peak Curation in Untargeted Metabolomics
Stancliffe, E. & Patti, G. J., Jun 27 2023, In: Analytical Chemistry. 95, 25, p. 9397-9403 7 p.Research output: Contribution to journal › Article › peer-review
2 Scopus citations -
Stromal DDR2 Promotes Ovarian Cancer Metastasis through Regulation of Metabolism and Secretion of Extracellular Matrix Proteins
Schab, A. M., Greenwade, M. M., Stock, E., Lomonosova, E., Cho, K., Grither, W. R., Noia, H., Wilke, D., Mullen, M. M., Hagemann, A. R., Hagemann, I. S., Thaker, P. H., Kuroki, L. M., McCourt, C. K., Khabele, D., Powell, M. A., Mutch, D. G., Zhao, P., Shriver, L. P. & Patti, G. J. & 2 others, , 2023, In: Molecular Cancer Research. 21, 11, p. 1234-1248 15 p.Research output: Contribution to journal › Article › peer-review
5 Scopus citations -
Uridine-derived ribose fuels glucose-restricted pancreatic cancer
Nwosu, Z. C., Ward, M. H., Sajjakulnukit, P., Poudel, P., Ragulan, C., Kasperek, S., Radyk, M., Sutton, D., Menjivar, R. E., Andren, A., Apiz-Saab, J. J., Tolstyka, Z., Brown, K., Lee, H. J., Dzierozynski, L. N., He, X., Ps, H., Ugras, J., Nyamundanda, G. & Zhang, L. & 9 others, , Jun 1 2023, In: Nature. 618, 7963, p. 151-158 8 p.Research output: Contribution to journal › Article › peer-review
Open Access44 Scopus citations -
Using mass spectrometry imaging to map fluxes quantitatively in the tumor ecosystem
Schwaiger-Haber, M., Stancliffe, E., Anbukumar, D. S., Sells, B., Yi, J., Cho, K., Adkins-Travis, K., Chheda, M. G., Shriver, L. P. & Patti, G. J., Dec 2023, In: Nature communications. 14, 1, 2876.Research output: Contribution to journal › Article › peer-review
Open Access22 Scopus citations -
2022
A multidimensional metabolomics workflow to image biodistribution and evaluate pharmacodynamics in adult zebrafish
Jackstadt, M. M., Chamberlain, C. A., Doonan, S. R., Shriver, L. P. & Patti, G. J., Aug 2022, In: DMM Disease Models and Mechanisms. 15, 8, dmm049550.Research output: Contribution to journal › Article › peer-review
Open Access6 Scopus citations -
An Untargeted Metabolomics Workflow that Scales to Thousands of Samples for Population-Based Studies
Stancliffe, E., Schwaiger-Haber, M., Sindelar, M., Murphy, M. J., Soerensen, M. & Patti, G. J., Dec 20 2022, In: Analytical Chemistry. 94, 50, p. 17370-17378 9 p.Research output: Contribution to journal › Article › peer-review
Open Access12 Scopus citations -
Combining Isotopologue Workflows and Simultaneous Multidimensional Separations to Detect, Identify, and Validate Metabolites in Untargeted Analyses
Dodds, J. N., Wang, L., Patti, G. J. & Baker, E. S., Feb 8 2022, In: Analytical Chemistry. 94, 5, p. 2527-2535 9 p.Research output: Contribution to journal › Article › peer-review
6 Scopus citations -
GAS6-AXL Inhibition by AVB-500 Overcomes Resistance to Paclitaxel in Endometrial Cancer by Decreasing Tumor Cell Glycolysis
Bruce, S. F., Cho, K., Noia, H., Lomonosova, E., Stock, E. C., Oplt, A., Blachut, B., Mullen, M. M., Kuroki, L. M., Hagemann, A. R., McCourt, C. K., Thaker, P. H., Khabele, D., Powell, M. A., Mutch, D. G., Shriver, L. P., Patti, G. J. & Fuh, K., Aug 2022, In: Molecular Cancer Therapeutics. 21, 8, p. 1348-1359 12 p.Research output: Contribution to journal › Article › peer-review
Open Access6 Scopus citations -
Mitochondrial pyruvate carrier inhibitors improve metabolic parameters in diet-induced obese mice
Hodges, W. T., Jarasvaraparn, C., Ferguson, D., Griffett, K., Gill, L. E., Chen, Y., Ilagan, M. X. G., Hegazy, L., Elgendy, B., Cho, K., Patti, G. J., McCommis, K. & Finck, B. N., Feb 1 2022, In: Journal of Biological Chemistry. 298, 2, 101554.Research output: Contribution to journal › Article › peer-review
Open Access20 Scopus citations -
Monounsaturated and Diunsaturated Fatty Acids Sensitize Cervical Cancer to Radiation Therapy
Muhammad, N., Ruiz, F., Stanley, J., Rashmi, R., Cho, K., Jayachandran, K., Zahner, M. C., Huang, Y., Zhang, J., Markovina, S., Patti, G. J. & Schwarz, J. K., Dec 1 2022, In: Cancer research. 82, 24, p. 4515-4527 13 p.Research output: Contribution to journal › Article › peer-review
Open Access13 Scopus citations -
MYC sensitises cells to apoptosis by driving energetic demand
Edwards-Hicks, J., Su, H., Mangolini, M., Yoneten, K. K., Wills, J., Rodriguez-Blanco, G., Young, C., Cho, K., Barker, H., Muir, M., Guerrieri, A. N., Li, X. F., White, R., Manasterski, P., Mandrou, E., Wills, K., Chen, J., Abraham, E., Sateri, K. & Qian, B. Z. & 13 others, , Dec 2022, In: Nature communications. 13, 1, 4674.Research output: Contribution to journal › Article › peer-review
Open Access17 Scopus citations -
Saturation of the mitochondrial NADH shuttles drives aerobic glycolysis in proliferating cells
Wang, Y., Stancliffe, E., Fowle-Grider, R., Wang, R., Wang, C., Schwaiger-Haber, M., Shriver, L. P. & Patti, G. J., Sep 1 2022, In: Molecular cell. 82, 17, p. 3270-3283.e9Research output: Contribution to journal › Article › peer-review
Open Access82 Scopus citations -
Sex differences in brain tumor glutamine metabolism reveal sex-specific vulnerabilities to treatment
Sponagel, J., Jones, J. K., Frankfater, C., Zhang, S., Tung, O., Cho, K., Tinkum, K. L., Gass, H., Nunez, E., Spitz, D. R., Chinnaiyan, P., Schaefer, J., Patti, G. J., Graham, M. S., Mauguen, A., Grkovski, M., Dunphy, M. P., Krebs, S., Luo, J. & Rubin, J. & 1 others, , Nov 11 2022, In: Med. 3, 11, p. 792-811.e12Research output: Contribution to journal › Article › peer-review
Open Access14 Scopus citations -
Silencing alanine transaminase 2 in diabetic liver attenuates hyperglycemia by reducing gluconeogenesis from amino acids
Martino, M. R., Gutiérrez-Aguilar, M., Yiew, N. K. H., Lutkewitte, A. J., Singer, J. M., McCommis, K., Ferguson, D., Liss, K. H. H., Yoshino, J., Renkemeyer, M. K., Smith, G. I., Cho, K., Fletcher, J. A., Klein, S., Patti, G. J., Burgess, S. C. & Finck, B. N., Apr 26 2022, In: Cell Reports. 39, 4, 110733.Research output: Contribution to journal › Article › peer-review
Open Access23 Scopus citations -
Targeting fatty acid β-oxidation impairs monocyte differentiation and prolongs heart allograft survival
Zhu, Y., Dun, H., Ye, L., Terada, Y., Shriver, L. P., Patti, G. J., Kreisel, D., Gelman, A. E. & Wong, B. W., Apr 8 2022, In: JCI Insight. 7, 7, e151596.Research output: Contribution to journal › Article › peer-review
Open Access10 Scopus citations -
The feel of inclusivity
Patti, K. M. & Patti, G. J., Aug 2022, In: Science Advances. 8, 33, eade0023.Research output: Contribution to journal › Article › peer-review
Open Access1 Scopus citations -
Worksite-based intensive lifestyle therapy has profound cardiometabolic benefits in people with obesity and type 2 diabetes
Yoshino, M., Yoshino, J., Smith, G. I., Stein, R. I., Bittel, A. J., Bittel, D. C., Reeds, D. N., Sinacore, D. R., Cade, T., Patterson, B. W., Cho, K., Patti, G. J., Mittendorfer, B. & Klein, S., Oct 4 2022, In: Cell metabolism. 34, 10, p. 1431-1441.e5Research output: Contribution to journal › Article › peer-review
Open Access11 Scopus citations -
2021
A Workflow to Perform Targeted Metabolomics at the Untargeted Scale on a Triple Quadrupole Mass Spectrometer
Schwaiger-Haber, M., Stancliffe, E., Arends, V., Thyagarajan, B., Sindelar, M. & Patti, G. J., Aug 18 2021, In: ACS Measurement Science Au. 1, 1, p. 35-45 11 p.Research output: Contribution to journal › Article › peer-review
Open Access27 Scopus citations -
DecoID improves identification rates in metabolomics through database-assisted MS/MS deconvolution
Stancliffe, E., Schwaiger-Haber, M., Sindelar, M. & Patti, G. J., Jul 2021, In: Nature Methods. 18, 7, p. 779-787 9 p.Research output: Contribution to journal › Article › peer-review
Open Access42 Scopus citations -
Deletion of Glut1 in early postnatal cartilage reprograms chondrocytes toward enhanced glutamine oxidation
Wang, C., Ying, J., Niu, X., Li, X., Patti, G. J., Shen, J. & O’Keefe, R. J., Dec 2021, In: Bone Research. 9, 1, 38.Research output: Contribution to journal › Article › peer-review
Open Access18 Scopus citations -
HERMES: a molecular-formula-oriented method to target the metabolome
Giné, R., Capellades, J., Badia, J. M., Vughs, D., Schwaiger-Haber, M., Alexandrov, T., Vinaixa, M., Brunner, A. M., Patti, G. J. & Yanes, O., Nov 2021, In: Nature Methods. 18, 11, p. 1370-1376 7 p.Research output: Contribution to journal › Article › peer-review
18 Scopus citations -
Hif1α is required for nk cell metabolic adaptation during virus infection
Victorino, F., Bigley, T. M., Park, E., Yao, C. H., Benoit, J., Yang, L. P., Piersma, S. J., Lauron, E. J., Davidson, R. M., Patti, G. J. & Yokoyama, W. M., Aug 2021, In: eLife. 10, e68484.Research output: Contribution to journal › Article › peer-review
Open Access15 Scopus citations -
Isotope tracing in adult zebrafish reveals alanine cycling between melanoma and liver
Naser, F. J., Jackstadt, M. M., Fowle-Grider, R., Spalding, J. L., Cho, K., Stancliffe, E., Doonan, S. R., Kramer, E. T., Yao, L., Krasnick, B., Ding, L., Fields, R. C., Kaufman, C. K., Shriver, L. P., Johnson, S. L. & Patti, G. J., Jul 6 2021, In: Cell metabolism. 33, 7, p. 1493-1504.e5Research output: Contribution to journal › Article › peer-review
Open Access28 Scopus citations -
Longitudinal metabolomics of human plasma reveals prognostic markers of COVID-19 disease severity
Sindelar, M., Stancliffe, E., Schwaiger-Haber, M., Anbukumar, D. S., Adkins-Travis, K., Goss, C. W., O'Halloran, J. A., Mudd, P. A., Liu, W. C., Albrecht, R. A., García-Sastre, A., Shriver, L. P. & Patti, G. J., Aug 17 2021, In: Cell Reports Medicine. 2, 8, 100369.Research output: Contribution to journal › Article › peer-review
Open Access62 Scopus citations -
Loss of SNORA73 reprograms cellular metabolism and protects against steatohepatitis
Sletten, A. C., Davidson, J. W., Yagabasan, B., Moores, S., Schwaiger-Haber, M., Fujiwara, H., Gale, S., Jiang, X., Sidhu, R., Gelman, S., Zhao, S., Patti, G., Ory, D. & Schaffer, J., Dec 1 2021, In: Nature communications. 12, 1, 5214.Research output: Contribution to journal › Article › peer-review
Open Access19 Scopus citations -
Nicotinamide mononucleotide increases muscle insulin sensitivity in prediabetic women
Yoshino, M., Yoshino, J., Kayser, B. D., Patti, G. J., Franczyk, M. P., Mills, K. F., Sindelar, M., Pietka, T., Patterson, B. W., Imai, S. I. & Klein, S., Jun 11 2021, In: Science. 372, 6547, p. 1224-1229 6 p.Research output: Contribution to journal › Article › peer-review
Open Access229 Scopus citations -
Quantitative rotational-echo double resonance for Carbon-13 spin clusters
Matsuoka, S., Sindelar, M., Bansal, S., Patti, G. J. & Schaefer, J., Sep 2021, In: Journal of Magnetic Resonance. 330, 107043.Research output: Contribution to journal › Article › peer-review
Open Access -
Targeting unique biological signals on the fly to improve MS/MS coverage and identification efficiency in metabolomics
Cho, K., Schwaiger-Haber, M., Naser, F. J., Stancliffe, E., Sindelar, M. & Patti, G. J., Mar 8 2021, In: Analytica Chimica Acta. 1149, 338210.Research output: Contribution to journal › Article › peer-review
Open Access22 Scopus citations -
2020
Alteration of Cellular Reduction Potential Will Change 64Cu-ATSM Signal With or Without Hypoxia
Floberg, J. M., Wang, L., Bandara, N., Rashmi, R., Mpoy, C., Garbow, J. R., Rogers, B. E., Patti, G. J. & Schwarz, J. K., Mar 1 2020, In: Journal of Nuclear Medicine. 61, 3, p. 427-432 6 p.Research output: Contribution to journal › Article › peer-review
Open Access14 Scopus citations -
Dietary serine-microbiota interaction enhances chemotherapeutic toxicity without altering drug conversion
Ke, W., Saba, J. A., Yao, C. H., Hilzendeger, M. A., Drangowska-Way, A., Joshi, C., Mony, V. K., Benjamin, S. B., Zhang, S., Locasale, J., Patti, G. J., Lewis, N. & O’Rourke, E. J., Dec 1 2020, In: Nature communications. 11, 1, 2587.Research output: Contribution to journal › Article › peer-review
Open Access32 Scopus citations -
Dose-Response Metabolomics to Understand Biochemical Mechanisms and Off-Target Drug Effects with the TOXcms Software
Yao, C. H., Wang, L., Stancliffe, E., Sindelar, M., Cho, K., Yin, W., Wang, Y. & Patti, G. J., Jan 21 2020, In: Analytical Chemistry. 92, 2, p. 1856-1864 9 p.Research output: Contribution to journal › Article › peer-review
26 Scopus citations -
Glutaminase inhibitors induce thiol-mediated oxidative stress and radiosensitization in treatment-resistant cervical cancers
Rashmi, R., Jayachandran, K., Zhang, J., Menon, V., Muhammad, N., Zahner, M., Ruiz, F., Zhang, S., Cho, K., Wang, Y., Huang, X., Huang, Y., McCormick, M. L., Rogers, B. E., Spitz, D. R., Patti, G. J. & Schwarz, J. K., Dec 1 2020, In: Molecular Cancer Therapeutics. 19, 12, p. 2465-2475 11 p.Research output: Contribution to journal › Article › peer-review
Open Access30 Scopus citations -
2019
Exogenous Monounsaturated Fatty Acids Promote a Ferroptosis-Resistant Cell State
Magtanong, L., Ko, P. J., To, M., Cao, J. Y., Forcina, G. C., Tarangelo, A., Ward, C. C., Cho, K., Patti, G. J., Nomura, D. K., Olzmann, J. A. & Dixon, S. J., Mar 21 2019, In: Cell Chemical Biology. 26, 3, p. 420-432.e9Research output: Contribution to journal › Article › peer-review
Open Access662 Scopus citations