Personal profile
Research interests
research primarily focuses on the regenerative medicine approaches to treat osteoarthritis, a painful and debilitating disease of the joints. His laboratory has used a multidisciplinary approach to investigate the role of biomechanical factors in the onset and progression of osteoarthritis, as a basis for the development of new pharmacologic and stem-cell therapies.
Mentoring
The Guilak Lab is dedicated to creating a nurturing, equitable, and inclusive environment. Dr. Guilak has won 5 university and international awards for his mentoring efforts.
Available to Mentor:
- PhD Students
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Collaborations and top research areas from the last five years
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Advances in RNA-based nanotherapies for arthritis
Pham, C. T. N. & Guilak, F., Feb 2026, In: Nature Reviews Rheumatology. 22, 2, p. 80-81 2 p.Research output: Contribution to journal › Review article › peer-review
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Associations of Sleep and Shift Work With Osteoarthritis Risk
Yanik, E. L., Bridgeman, A., Herzog, E. D., Pham, V., Evanoff, B. A. & Guilak, F., 2026, (Accepted/In press) In: Arthritis Care and Research.Research output: Contribution to journal › Article › peer-review
Open Access -
Osteoarthritis as a systemic disease
Collins, K. H., Haugen, I. K., Neogi, T. & Guilak, F., Feb 2026, In: Nature Reviews Rheumatology. 22, 2, p. 105-117 13 p.Research output: Contribution to journal › Review article › peer-review
3 Link opens in a new tab Scopus citations -
PIEZO mechanosensitivity in chondrocytes is differentially modulated by L-type and T-type voltage-sensitive ion channels
Savadipour, A., Marushack, G. K., Nims, R. J., Garcia-Castorena, J. M., Liedtke, W. & Guilak, F., Mar 2026, In: Osteoarthritis and Cartilage Open. 8, 1, 100710.Research output: Contribution to journal › Article › peer-review
Open Access1 Link opens in a new tab Scopus citations -
Reply to the Letter to the Editor: How Does Tendon Region, Donor, and the Presence of Disease Affect Protein Composition of the Achilles Tendon?
Zellers, J. A., Vaidya, R. S., Backus, J., McCormick, J., Lake, S. P., Tang, S. Y. & Guilak, F., Feb 2026, In: Clinical orthopaedics and related research. 484, 2, p. 406-407 2 p.Research output: Contribution to journal › Letter › peer-review